| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| J Daléry, V Aubi. [Comparative study of paroxetine and mianserin in depression in elderly patients: efficacy, tolerance, serotonin dependence]. L'Encephale. vol 27. issue 1. 2001-06-07. PMID:11294041. |
[comparative study of paroxetine and mianserin in depression in elderly patients: efficacy, tolerance, serotonin dependence]. |
2001-06-07 |
2023-08-12 |
Not clear |
| J Daléry, V Aubi. [Comparative study of paroxetine and mianserin in depression in elderly patients: efficacy, tolerance, serotonin dependence]. L'Encephale. vol 27. issue 1. 2001-06-07. PMID:11294041. |
the tool used for this latter purpose was the aubin-jouvent-rating-scale (ajrs) which was designed to assess the deficit of serotonin: this is a scale with 10 items, some of them regrouped into a "general" factor (irritability, sudden mood change, impatience, aggressivity) or a "depression" factor (pain, anxiety, suicidal ideas) with additional items related to sleep disorders, abnormalities in eating behavior and inability to tolerate isolation. |
2001-06-07 |
2023-08-12 |
Not clear |
| S Kantor, M Graf, Z E Anheuer, G Bagd. Rapid desensitization of 5-HT(1A) receptors in Fawn-Hooded rats after chronic fluoxetine treatment. European neuropsychopharmacology : the journal of the European College of Neuropsychopharmacology. vol 11. issue 1. 2001-05-31. PMID:11226808. |
anxiety, platelet serotonin (5-ht) content and functions of the 5-ht(1a) receptor agonist 8-hydroxy-2-(di-n-propylamino)tetralin (8-oh-dpat) were measured in sprague--dawley (sd) and fawn-hooded (fh) rats, a strain with genetically impaired 5-ht storage and reuptake system and a putative model of depression and anxiety. |
2001-05-31 |
2023-08-12 |
rat |
| b' N Pivac, D M\\xc3\\xbcck-Seler, I Barisi\\xc4\\x87, M Jakovljevi\\xc4\\x87, Z Pureti\\xc4\\x8. Platelet serotonin concentration in dialysis patients with somatic symptoms of depression. Life sciences. vol 68. issue 21. 2001-05-24. PMID:11350013.' |
platelet serotonin concentration in dialysis patients with somatic symptoms of depression. |
2001-05-24 |
2023-08-12 |
human |
| b' N Pivac, D M\\xc3\\xbcck-Seler, I Barisi\\xc4\\x87, M Jakovljevi\\xc4\\x87, Z Pureti\\xc4\\x8. Platelet serotonin concentration in dialysis patients with somatic symptoms of depression. Life sciences. vol 68. issue 21. 2001-05-24. PMID:11350013.' |
platelet serotonin (5-ht) concentration was measured in 65 male and 45 female chronic renal patients on hemodialysis (hd) with different somatic symptoms of depression (crying spells, irritability, sleep disturbance, fatigability, loss of appetite, weight loss, somatic preoccupation and loss of libido), to find out the relationship between the severity of symptoms and platelet 5-ht concentration. |
2001-05-24 |
2023-08-12 |
human |
| D J Knapp, L J Sim-Selley, G R Breese, D H Overstree. Selective breeding of 5-HT(1A) receptor-mediated responses: application to emotion and receptor action. Pharmacology, biochemistry, and behavior. vol 67. issue 4. 2001-05-17. PMID:11166060. |
rat lines that were selectively bred for high (high dpat-sensitive, hds) or low (low dpat-sensitive, lds) hypothermic responses to the specific 5-ht(1a) receptor agonist, 8-hydroxy-di-n-propylaminotetralin (8-oh-dpat), differ in receptor binding and certain behaviors related to anxiety and depression. |
2001-05-17 |
2023-08-12 |
rat |
| R Stain-Malmgren, A E Khoury, A Aberg-Wistedt, A Tha. Serotonergic function in major depression and effect of sertraline and paroxetine treatment. International clinical psychopharmacology. vol 16. issue 2. 2001-05-17. PMID:11236074. |
we investigated platelet [14c]serotonin (5-ht) uptake and lysergic acid diethylamide [n-methyl-3h] ([3h]lsd)- and phenyl-6'-paroxetine ([3h]paroxetine) binding in 30 patients with major depression at baseline and after 6 months of treatment with either paroxetine or sertraline. |
2001-05-17 |
2023-08-12 |
human |
| A Weizman, R Weizma. Serotonin transporter polymorphism and response to SSRIs in major depression and relevance to anxiety disorders and substance abuse. Pharmacogenomics. vol 1. issue 3. 2001-04-26. PMID:11256582. |
serotonin transporter polymorphism and response to ssris in major depression and relevance to anxiety disorders and substance abuse. |
2001-04-26 |
2023-08-12 |
Not clear |
| A Weizman, R Weizma. Serotonin transporter polymorphism and response to SSRIs in major depression and relevance to anxiety disorders and substance abuse. Pharmacogenomics. vol 1. issue 3. 2001-04-26. PMID:11256582. |
the selective serotonin re-uptake inhibitors (ssris) which modulate serotonergic activity are effective in the treatment of serotonin-related mental disorders, such as depression and anxiety. |
2001-04-26 |
2023-08-12 |
Not clear |
| N Pitsika. Duloxetine Eli Lilly & Co. Current opinion in investigational drugs (London, England : 2000). vol 1. issue 1. 2001-04-19. PMID:11249587. |
duloxetine eli lilly & co. lilly is developing duloxetine, a 5-ht and norepinephrine uptake inhibitor as a potential treatment for depression and urinary incontinence. |
2001-04-19 |
2023-08-12 |
Not clear |
| C G Gottfries, I Karlsso. [Depression and anxiety in the elderly still underdiagnosed. SSRI preparations in conjunction with psychotherapy provide effective treatment]. Lakartidningen. vol 98. issue 8. 2001-04-19. PMID:11265567. |
selective serotonin reuptake inhibitors (ssris) are the drugs of choice in the treatment of elderly people with depression and anxiety disorders. |
2001-04-19 |
2023-08-12 |
Not clear |
| S Mace, D Taylo. Selective serotonin reuptake inhibitors: a review of efficacy and tolerability in depression. Expert opinion on pharmacotherapy. vol 1. issue 5. 2001-04-05. PMID:11249500. |
selective serotonin reuptake inhibitors: a review of efficacy and tolerability in depression. |
2001-04-05 |
2023-08-12 |
Not clear |
| S Mace, D Taylo. Selective serotonin reuptake inhibitors: a review of efficacy and tolerability in depression. Expert opinion on pharmacotherapy. vol 1. issue 5. 2001-04-05. PMID:11249500. |
selective serotonin reuptake inhibitors (ssris) are now generally regarded as effective and better tolerated alternatives to tricyclic antidepressants (tcas) for the treatment of depression. |
2001-04-05 |
2023-08-12 |
Not clear |
| C J Hunt, L M Shepherd, G Andrew. Do doctors know best? Comments on a failed trial. The Medical journal of Australia. vol 174. issue 3. 2001-03-29. PMID:11247619. |
a randomised controlled trial was planned to compare two different treatment strategies--structured problem solving and selective serotonin reuptake inhibitor (ssri) medication--for patients with mild to moderate major depression. |
2001-03-29 |
2023-08-12 |
Not clear |
| P J Panzarino, D B Nas. Cost-effective treatment of depression with selective serotonin reuptake inhibitors. The American journal of managed care. vol 7. issue 2. 2001-03-22. PMID:11216334. |
cost-effective treatment of depression with selective serotonin reuptake inhibitors. |
2001-03-22 |
2023-08-12 |
Not clear |
| P Blier, F V Abbot. Putative mechanisms of action of antidepressant drugs in affective and anxiety disorders and pain. Journal of psychiatry & neuroscience : JPN. vol 26. issue 1. 2001-03-15. PMID:11212592. |
an enhancement of neurotransmission of serotonin (5-ht), noradrenaline, or both, underlies the antidepressant response associated with most agents presently available to treat major depression. |
2001-03-15 |
2023-08-12 |
Not clear |
| P Blier, F V Abbot. Putative mechanisms of action of antidepressant drugs in affective and anxiety disorders and pain. Journal of psychiatry & neuroscience : JPN. vol 26. issue 1. 2001-03-15. PMID:11212592. |
the doses of medication and the durations of treatment necessary to obtain these alterations in 5-ht transmission in various brain structures of laboratory animals are fully consistent with the conditions in the clinic necessary to attenuate symptoms in depression and ocd. |
2001-03-15 |
2023-08-12 |
Not clear |
| D A Banaza. Minor depression in primary care. The Journal of the American Osteopathic Association. vol 100. issue 12. 2001-03-15. PMID:11213666. |
cognitive-behavioral modes of therapy and selective serotonin reuptake inhibitor antidepressants have demonstrated efficacy for primary care patients who have minor depression. |
2001-03-15 |
2023-08-12 |
Not clear |
| F Licata, G Li Volsi, M Di Mauro, G Fretto, L Ciranna, F Santangel. Serotonin modifies the neuronal inhibitory responses to gamma-aminobutyric acid in the red nucleus: a microiontophoretic study in the rat. Experimental neurology. vol 167. issue 1. 2001-03-08. PMID:11161597. |
in fact, 5-ht induced an enhancement of the gaba responses in neurons mostly located in the rostral rn and a depression in those in the caudal rn. |
2001-03-08 |
2023-08-12 |
rat |
| M B Kelle. Citalopram therapy for depression: a review of 10 years of European experience and data from U.S. clinical trials. The Journal of clinical psychiatry. vol 61. issue 12. 2001-03-01. PMID:11206593. |
this review summarizes and evaluates clinical experience with citalopram, the latest selective serotonin reuptake inhibitor (ssri) to be approved for the treatment of depression in the united states. |
2001-03-01 |
2023-08-12 |
Not clear |