| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Alexander Neumeister, Anastasios Konstantinidis, Juergen Stastny, Markus J Schwarz, Oliver Vitouch, Matthaus Willeit, Nicole Praschak-Rieder, Johanna Zach, Martina de Zwaan, Brigitta Bondy, Manfred Ackenheil, Siegfried Kaspe. Association between serotonin transporter gene promoter polymorphism (5HTTLPR) and behavioral responses to tryptophan depletion in healthy women with and without family history of depression. Archives of general psychiatry. vol 59. issue 7. 2002-08-06. PMID:12090814. |
evidence suggests that serotonin transporter gene promoter polymorphism (5httlpr)-dependent low transcriptional activity of the human serotonin transporter gene may be a genetic susceptibility factor for depression. |
2002-08-06 |
2023-08-12 |
human |
| Raúl de la Fuente-Fernández, A Jon Stoess. The placebo effect in Parkinson's disease. Trends in neurosciences. vol 25. issue 6. 2002-07-30. PMID:12086748. |
opioids in pain disorders, serotonin in depression). |
2002-07-30 |
2023-08-12 |
Not clear |
| Yoshihisa Kitamura, Hiroaki Araki, Yutaka Gomit. [Interaction of 5-HT and HPA axis in depression and treatment-resistant depression]. Nihon yakurigaku zasshi. Folia pharmacologica Japonica. vol 119. issue 6. 2002-07-26. PMID:12089903. |
[interaction of 5-ht and hpa axis in depression and treatment-resistant depression]. |
2002-07-26 |
2023-08-12 |
rat |
| Yoshihisa Kitamura, Hiroaki Araki, Yutaka Gomit. [Interaction of 5-HT and HPA axis in depression and treatment-resistant depression]. Nihon yakurigaku zasshi. Folia pharmacologica Japonica. vol 119. issue 6. 2002-07-26. PMID:12089903. |
we believe that behavioral pharmacological and molecular biological research into the interaction between the 5-ht and hpa axis will elucidate the pathogenesis of depression or antidepressant-treatment-resistant depression and the mechanism of antidepressants action. |
2002-07-26 |
2023-08-12 |
rat |
| C Nocjar, B L Roth, E A Pehe. Localization of 5-HT(2A) receptors on dopamine cells in subnuclei of the midbrain A10 cell group. Neuroscience. vol 111. issue 1. 2002-07-18. PMID:11955720. |
considerable evidence suggests that a dysfunction of the dopamine and serotonin (5-hydroxytryptamine or 5-ht) neurotransmitter systems contributes to a diverse range of pathological conditions including schizophrenia, depression and drug abuse. |
2002-07-18 |
2023-08-12 |
rat |
| E Hilger, N Praschak-Rieder, M Willeit, J Stastny, A Konstandinidis, A Neumeister, S Kaspe. [Pharmacotherapy of seasonal depression]. Der Nervenarzt. vol 73. issue 1. 2002-07-18. PMID:11975060. |
so far, selective serotonin reuptake inhibitors and possibly compounds with a distinct noradrenergic mechanism of action seem to be the treatment of choice for seasonal depression. |
2002-07-18 |
2023-08-12 |
Not clear |
| H Dhaene. Imaging the serotonergic system in depression. European archives of psychiatry and clinical neuroscience. vol 251 Suppl 2. 2002-07-17. PMID:11824843. |
the serotonin transporter availability seems to be reduced in depression. |
2002-07-17 |
2023-08-12 |
Not clear |
| Michelle F Anderson, Maria A I Aberg, Michael Nilsson, Peter S Eriksso. Insulin-like growth factor-I and neurogenesis in the adult mammalian brain. Brain research. Developmental brain research. vol 134. issue 1-2. 2002-07-16. PMID:11947942. |
similarly, stress and depression also inhibit neurogenesis, possibly via the associated reductions in serotonin or increases in circulating glucocorticoids. |
2002-07-16 |
2023-08-12 |
rat |
| M L López-Rodríguez, D Ayala, B Benhamú, M J Morcillo, A Vis. Arylpiperazine derivatives acting at 5-HT(1A) receptors. Current medicinal chemistry. vol 9. issue 4. 2002-07-15. PMID:11945120. |
among 5-htrs, the 5-ht(1a) subtype is the best studied and it is generally accepted that it is involved in psychiatric disorders such as anxiety and depression. |
2002-07-15 |
2023-08-12 |
Not clear |
| Wanda Foltyn, Ewa Nowakowska-Zajdel, Aleksander Danikiewicz, Andrzej Brodzia. [Hypothalamic-pituitary-thyroid axis in depression]. Psychiatria polska. vol 36. issue 2. 2002-07-09. PMID:12043045. |
this theory seems to be compatible with the serotonin deficiency hypothesis of depression. |
2002-07-09 |
2023-08-12 |
Not clear |
| Wanda Foltyn, Ewa Nowakowska-Zajdel, Aleksander Danikiewicz, Andrzej Brodzia. [Hypothalamic-pituitary-thyroid axis in depression]. Psychiatria polska. vol 36. issue 2. 2002-07-09. PMID:12043045. |
trh remains under a constant inhibition by serotonin and reduced intracerebral serotonin concentration seen in depression will lead to increased trh concentration in brain tissue. |
2002-07-09 |
2023-08-12 |
Not clear |
| E Sibille, R He. Combining genetic and genomic approaches to study mood disorders. European neuropsychopharmacology : the journal of the European College of Neuropsychopharmacology. vol 11. issue 6. 2002-07-03. PMID:11704418. |
the serotonin system, and the serotonin(1a) (5-ht(1a)) receptor in particular, have been under intense investigation, mostly due to the fact that serotonergic drugs that directly or indirectly affect the 5-ht(1a) receptor, are effective therapeutic agents in treating patients with various neuropsychiatric disorders, including anxiety and depression. |
2002-07-03 |
2023-08-12 |
mouse |
| E Weimer, D F Braus, I Cavus, J Thom. [Augmentation of selective serotonin reuptake inhibitors (SSRI) with atypical antipsychotics in the treatment of depression]. Fortschritte der Neurologie-Psychiatrie. vol 70. issue 4. 2002-06-20. PMID:11948436. |
[augmentation of selective serotonin reuptake inhibitors (ssri) with atypical antipsychotics in the treatment of depression]. |
2002-06-20 |
2023-08-12 |
Not clear |
| Luca Ferraro, Kjell Fuxe, Sergio Tanganelli, Maria Cristina Tomasini, Francis A Rambert, Tiziana Antonell. Differential enhancement of dialysate serotonin levels in distinct brain regions of the awake rat by modafinil: possible relevance for wakefulness and depression. Journal of neuroscience research. vol 68. issue 1. 2002-06-18. PMID:11933055. |
differential enhancement of dialysate serotonin levels in distinct brain regions of the awake rat by modafinil: possible relevance for wakefulness and depression. |
2002-06-18 |
2023-08-12 |
rat |
| Rolf Kaiser, Bruno Müller-Oerlinghausen, Diana Filler, Pierre-Benoit Tremblay, Anne Berghöfer, Ivar Roots, Jürgen Brockmölle. Correlation between serotonin uptake in human blood platelets with the 44-bp polymorphism and the 17-bp variable number of tandem repeat of the serotonin transporter. American journal of medical genetics. vol 114. issue 3. 2002-06-17. PMID:11920857. |
dysfunctions of the central serotonin (5-hydroxytryptamine, 5-ht) system seem to be associated with psychiatric disorders such as schizophrenia or depression. |
2002-06-17 |
2023-08-12 |
human |
| A Zangen, R Nakash, I Roth-Deri, D H Overstreet, G Yadi. Impaired release of beta-endorphin in response to serotonin in a rat model of depression. Neuroscience. vol 110. issue 3. 2002-06-12. PMID:11906780. |
impaired release of beta-endorphin in response to serotonin in a rat model of depression. |
2002-06-12 |
2023-08-12 |
rat |
| A W Ravna, O Edvardse. A putative three-dimensional arrangement of the human serotonin transporter transmembrane helices: a tool to aid experimental studies. Journal of molecular graphics & modelling. vol 20. issue 2. 2002-06-10. PMID:11775000. |
the human serotonin transporter is the molecular target for selective serotonin reuptake inhibitor drugs which are being used for treatment of depression. |
2002-06-10 |
2023-08-12 |
human |
| Lut Tamam, Nurgul Ozpoyra. Selective serotonin reuptake inhibitor discontinuation syndrome: a review. Advances in therapy. vol 19. issue 1. 2002-06-06. PMID:12008858. |
selective serotonin reuptake inhibitors (ssris) are widely prescribed in the treatment of depression and anxiety, as well as obsessive-compulsive, eating, and impulse-control disorders. |
2002-06-06 |
2023-08-12 |
Not clear |
| Lauren B Marangell, Christopher R Johnson, Barbara Kertz, Holly A Zboyan, James M Martine. Olanzapine in the treatment of apathy in previously depressed participants maintained with selective serotonin reuptake inhibitors: an open-label, flexible-dose study. The Journal of clinical psychiatry. vol 63. issue 5. 2002-06-06. PMID:12019662. |
we report a clinical trial of olanzapine in the treatment of prominent apathy in the absence of depression in patients on long-term treatment with selective serotonin reuptake inhibitors (ssris) for nonpsychotic major depression. |
2002-06-06 |
2023-08-12 |
human |
| Stephen M Stah. Does depression hurt? The Journal of clinical psychiatry. vol 63. issue 4. 2002-05-31. PMID:12000200. |
ascending serotonergic and noradrenergic pathways may mediate the emotional and vegetative symptoms of depression and can potentially be targets of serotonin and norepinephrine reuptake inhibitors to obtain relief of these symptoms. |
2002-05-31 |
2023-08-12 |
Not clear |