| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Janna Leigh Morrison, Caly Chien, Kenneth Wayne Riggs, Nancy Gruber, Dan Rura. Effect of maternal fluoxetine administration on uterine blood flow, fetal blood gas status, and growth. Pediatric research. vol 51. issue 4. 2002-11-26. PMID:11919327. |
fluoxetine, a selective serotonin reuptake inhibitor, is often prescribed to treat depression due to its efficacy, high margin of safety, and mild side effects. |
2002-11-26 |
2023-08-12 |
Not clear |
| Tim F Oberlander, Ruth Eckstein Grunau, Colleen Fitzgerald, Ann-Louise Ellwood, Shaila Misri, Dan Rurak, Kenneth Wayne Rigg. Prolonged prenatal psychotropic medication exposure alters neonatal acute pain response. Pediatric research. vol 51. issue 4. 2002-11-26. PMID:11919328. |
selective serotonin reuptake inhibitors (ssris) and benzodiazepines are frequently used to treat maternal depression during pregnancy, however the effect of increased serotonin (5ht) and gamma-amino-butyric acid (gaba) agonists in the fetal human brain remains unknown. |
2002-11-26 |
2023-08-12 |
human |
| Kelly Shaw, Jane Turner, Christopher Del Ma. Are tryptophan and 5-hydroxytryptophan effective treatments for depression? A meta-analysis. The Australian and New Zealand journal of psychiatry. vol 36. issue 4. 2002-11-25. PMID:12169147. |
to review the literature regarding the effectiveness of 5-hydroxytryptophan (5-ht) and l-tryptophan in the treatment of unipolar depression. |
2002-11-25 |
2023-08-12 |
Not clear |
| Z Xu, F J Seidler, M M Cousins, W Slikker, T A Slotki. Adolescent nicotine administration alters serotonin receptors and cell signaling mediated through adenylyl cyclase. Brain research. vol 951. issue 2. 2002-11-25. PMID:12270507. |
the direction of change, emergence of defects after the cessation of nicotine administration, and sex-preference for effects in females, all support a relationship of impaired 5ht function to the higher incidence of depression seen in adolescent smokers. |
2002-11-25 |
2023-08-12 |
rat |
| Tai-Jui Chen, Y W-Y Yu, Ming-Chao Chen, Shih-Jen Tsai, Chen-Jee Hon. Association analysis for serotonin transporter promoter polymorphism and auditory evoked potentials for major depression. Neuropsychobiology. vol 46. issue 2. 2002-11-25. PMID:12378120. |
association analysis for serotonin transporter promoter polymorphism and auditory evoked potentials for major depression. |
2002-11-25 |
2023-08-12 |
Not clear |
| Pierre Baumann, Daniele F Zullino, Chin B Ea. Enantiomers' potential in psychopharmacology--a critical analysis with special emphasis on the antidepressant escitalopram. European neuropsychopharmacology : the journal of the European College of Neuropsychopharmacology. vol 12. issue 5. 2002-11-22. PMID:12208561. |
emphasis is given to the treatment of depression and how the potential of one pure enantiomer-escitalopram, the s-enantiomer of the selective serotonin reuptake inhibitor citalopram-appears to be fulfilling its preclinical promise in the clinic. |
2002-11-22 |
2023-08-12 |
Not clear |
| N Brunello, J Mendlewicz, S Kasper, B Leonard, S Montgomery, J Nelson, E Paykel, M Versiani, G Racagn. The role of noradrenaline and selective noradrenaline reuptake inhibition in depression. European neuropsychopharmacology : the journal of the European College of Neuropsychopharmacology. vol 12. issue 5. 2002-11-22. PMID:12208564. |
for the past 10 years, clinicians have focused on serotonin in their treatment of depression. |
2002-11-22 |
2023-08-12 |
Not clear |
| N Brunello, J Mendlewicz, S Kasper, B Leonard, S Montgomery, J Nelson, E Paykel, M Versiani, G Racagn. The role of noradrenaline and selective noradrenaline reuptake inhibition in depression. European neuropsychopharmacology : the journal of the European College of Neuropsychopharmacology. vol 12. issue 5. 2002-11-22. PMID:12208564. |
until recently, the role of noradrenaline in depression was predicted from clinical experience with noradrenergic tcas (desipramine, nortriptyline and protriptyline) and selective serotonin and noradrenaline reuptake inhibitors (venlafaxine, milnacipran). |
2002-11-22 |
2023-08-12 |
Not clear |
| A Gupta, K Pansari, H Shett. Post-stroke depression. International journal of clinical practice. vol 56. issue 7. 2002-11-22. PMID:12296616. |
depression following stroke can impede recovery and rehabilitation and is associated with higher mortality randomised trials show that antidepressants, especially selective serotonin uptake inhibitors, are effective in the treatment of this condition. |
2002-11-22 |
2023-08-12 |
Not clear |
| Ingrid Østby-Deglum, Alv A Dah. [How is an information program for depressed patients perceived?]. Tidsskrift for den Norske laegeforening : tidsskrift for praktisk medicin, ny raekke. vol 122. issue 19. 2002-11-08. PMID:12362709. |
"laere og støtte" (los) is the norwegian version of an information programme (rhythms) developed in the united states for patients with depression who are treated with selective serotonin reuptake inhibitors (ssri) in general practice. |
2002-11-08 |
2023-08-12 |
Not clear |
| A P Van Amerongen, G Ferrey, A Tournou. A randomised, double-blind comparison of milnacipran and imipramine in the treatment of depression. Journal of affective disorders. vol 72. issue 1. 2002-10-28. PMID:12204314. |
this multicentre, double-blind, randomised trial in 109 patients compared the efficacy and tolerance of the novel selective serotonin and noradrenaline reuptake inhibitor (snri) antidepressant milnacipran (50 mg twice daily, n=53) with the established tricyclic agent imipramine (75 mg twice daily, n=56) over a period of 6 weeks, in patients with major depression (montgomery-asberg depression rating score (madrs) > or =25). |
2002-10-28 |
2023-08-12 |
Not clear |
| J Vallejo, P Rosel, B Arranz, M Urretavizcaya, J M Menchón, F Contreras, M A Navarr. Loss of the circadian variation of platelet [3H]imipramine binding in delusional compared with non-delusional endogenously depressed patients. Journal of affective disorders. vol 72. issue 1. 2002-10-28. PMID:12204323. |
the circadian variations of the serotonin reuptake sites were studied in 16 patients meeting dsm-iv criteria for major depression with melancholia, either with (n=8) or without (n=8) psychotic symptomatology. |
2002-10-28 |
2023-08-12 |
Not clear |
| Cynthia L Harde. The co-morbidity of depression and epilepsy: epidemiology, etiology, and treatment. Neurology. vol 59. issue 6 Suppl 4. 2002-10-17. PMID:12270969. |
when antidepressants are necessary to treat depression in patients with epilepsy, selective serotonin reuptake inhibitors (ssris) and multireceptor antidepressants are considered first-line treatments. |
2002-10-17 |
2023-08-12 |
Not clear |
| Larry A Dent, Waylon C Brown, Jenny D Murne. Citalopram-induced priapism. Pharmacotherapy. vol 22. issue 4. 2002-10-11. PMID:11939691. |
citalopram is a relatively new selective serotonin reuptake inhibitor (ssri) that is becoming widely administered for the treatment of depression. |
2002-10-11 |
2023-08-12 |
Not clear |
| C Shen, H Li, E Melle. Repeated treatment with antidepressants differentially alters 5-HT1A agonist-stimulated [35S]GTP gamma S binding in rat brain regions. Neuropharmacology. vol 42. issue 8. 2002-10-11. PMID:12128004. |
electrophysiological studies have led to the proposal that the neurobiological mechanism(s) underlying drug therapy of anxiety and depression involve(s) regionally specific adaptations in 5-ht(1a) receptor sensitivity. |
2002-10-11 |
2023-08-12 |
rat |
| Rosa M Tordera, Antonio Monge, Joaquín Del Río, Berta Lashera. Antidepressant-like activity of VN2222, a serotonin reuptake inhibitor with high affinity at 5-HT1A receptors. European journal of pharmacology. vol 442. issue 1-2. 2002-10-08. PMID:12020683. |
consequently, vn2222 is a new compound with a dual effect on the serotonergic system, as 5-ht uptake blocker and 5-ht1a receptor partial agonist, and with a remarkable activity in an animal model of depression with high predictive validity. |
2002-10-08 |
2023-08-12 |
mouse |
| Vadim D Khait, Yung-Yu Huang, Kevin M Malone, Maria Oquendo, Beth Brodsky, Leo Sher, J John Man. Is there circannual variation of human platelet 5-HT(2A) binding in depression? Journal of affective disorders. vol 71. issue 1-3. 2002-10-08. PMID:12167525. |
is there circannual variation of human platelet 5-ht(2a) binding in depression? |
2002-10-08 |
2023-08-12 |
human |
| G J Wan, W H Crown, E R Berndt, S N Finkelstein, D Lin. Healthcare expenditure in patients treated with venlafaxine or selective serotonin reuptake inhibitors for depression and anxiety. International journal of clinical practice. vol 56. issue 6. 2002-09-27. PMID:12166541. |
healthcare expenditure in patients treated with venlafaxine or selective serotonin reuptake inhibitors for depression and anxiety. |
2002-09-27 |
2023-08-12 |
Not clear |
| Mauro Federici, Silvia Natoli, Giorgio Bernardi, Nicola B Mercur. Dopamine selectively reduces GABA(B) transmission onto dopaminergic neurones by an unconventional presynaptic action. The Journal of physiology. vol 540. issue Pt 1. 2002-09-23. PMID:11927674. |
the da-induced depression of the gaba(b) ipsp occluded the depression produced by serotonin and was not antagonized by serotonin antagonists. |
2002-09-23 |
2023-08-12 |
Not clear |
| Shigehiro Hirose, Charles R Ashb. An open pilot study combining risperidone and a selective serotonin reuptake inhibitor as initial antidepressant therapy. The Journal of clinical psychiatry. vol 63. issue 8. 2002-09-20. PMID:12197455. |
atypical antipsychotics such as risperidone or olanzapine have been reported to be effective when added to a selective serotonin reuptake inhibitor (ssri) in cases of depression in which treatment with an ssri alone is not effective. |
2002-09-20 |
2023-08-12 |
Not clear |