| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Clive Ballard, Mary Johnson, Margaret Piggott, Robert Perry, John O'Brien, Elise Rowan, Elaine Perry, Peter Lantos, Nigel Cairns, Clive Holme. A positive association between 5HT re-uptake binding sites and depression in dementia with Lewy bodies. Journal of affective disorders. vol 69. issue 1-3. 2003-02-24. PMID:12103469. |
a positive association between 5ht re-uptake binding sites and depression in dementia with lewy bodies. |
2003-02-24 |
2023-08-12 |
Not clear |
| Michelle Roche, Kathryn G Commons, Andrew Peoples, Rita J Valentin. Circuitry underlying regulation of the serotonergic system by swim stress. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 23. issue 3. 2003-02-21. PMID:12574426. |
the dorsal raphe nucleus (dr)-serotonin (5-ht) system has been implicated in depression and is dramatically affected by swim stress, an animal model with predictive value for antidepressants. |
2003-02-21 |
2023-08-12 |
Not clear |
| Richard Kinkead, Olivier Belzile, Roumiana Gulemetov. Serotonergic modulation of respiratory motor output during tadpole development. Journal of applied physiology (Bethesda, Md. : 1985). vol 93. issue 3. 2003-02-14. PMID:12183489. |
recording of motor output related to gill and lung ventilation showed that 5-ht elicits a dose-dependent depression of gill burst frequency in both groups. |
2003-02-14 |
2023-08-12 |
Not clear |
| Thomas J Spencer, Joseph Biederman, Timothy E Wilens, Stephen V Faraon. Novel treatments for attention-deficit/hyperactivity disorder in children. The Journal of clinical psychiatry. vol 63 Suppl 12. 2003-02-11. PMID:12562057. |
serotonin reuptake inhibitors have little or no effect in adhd but may improve comorbid depression. |
2003-02-11 |
2023-08-12 |
Not clear |
| K Ranga, R Krishna. Clinical experience with substance P receptor (NK1) antagonists in depression. The Journal of clinical psychiatry. vol 63 Suppl 11. 2003-02-11. PMID:12562140. |
in phase 2 trials, therapy with the spas aprepitant (mk-0869) and compound a resulted in improvements in depression and anxiety symptoms that were quantitatively comparable with those seen with selective serotonin reuptake inhibitors (ssris) and significantly greater than those seen with placebo. |
2003-02-11 |
2023-08-12 |
Not clear |
| Yolanda Zea-Ponce, Lawrence S Kegeles, Ningning Guo, Leonid Raskin, Venkatesalu Bakthavachalam, Marc Laruell. Pharmacokinetics and brain distribution in non human primate of R(-)[123I]DOI, A 5HT(2A/2C) serotonin agonist. Nuclear medicine and biology. vol 29. issue 5. 2003-02-10. PMID:12088728. |
the purpose was to evaluate this radiotracer as a potential tool in discerning the role of the agonist high affinity state of 5-ht(2) receptors in depression and other neurological disorders. |
2003-02-10 |
2023-08-12 |
human |
| Alain Braconnier, Remi Le Coent, David Cohe. Paroxetine versus clomipramine in adolescents with severe major depression: a double-blind, randomized, multicenter trial. Journal of the American Academy of Child and Adolescent Psychiatry. vol 42. issue 1. 2003-02-06. PMID:12500073. |
to date, two randomized, double-blind trials of serotonin reuptake inhibitors (sris) have shown that antidepressant drugs are effective in treating adolescent depression. |
2003-02-06 |
2023-08-12 |
Not clear |
| Diana Shye, Jonathan B Brown, John P Mullooly, Gregory A Nichol. Understanding changes in primary care clinicians' satisfaction from depression care activities during adoption of selective serotonin reuptake inhibitors. The American journal of managed care. vol 8. issue 11. 2003-02-05. PMID:12437311. |
understanding changes in primary care clinicians' satisfaction from depression care activities during adoption of selective serotonin reuptake inhibitors. |
2003-02-05 |
2023-08-12 |
Not clear |
| Diana Shye, Jonathan B Brown, John P Mullooly, Gregory A Nichol. Understanding changes in primary care clinicians' satisfaction from depression care activities during adoption of selective serotonin reuptake inhibitors. The American journal of managed care. vol 8. issue 11. 2003-02-05. PMID:12437311. |
to describe how primary care clinicians' perceptions about depression care as a clinical activity changed during the adoption of selective serotonin reuptake inhibitors (ssris) in their health maintenance organization (hmo). |
2003-02-05 |
2023-08-12 |
Not clear |
| G E Tafet, V P Idoyaga-Vargas, D P Abulafia, J M Calandria, S S Roffman, A Chiovetta, M Shinitzk. Correlation between cortisol level and serotonin uptake in patients with chronic stress and depression. Cognitive, affective & behavioral neuroscience. vol 1. issue 4. 2003-01-30. PMID:12467090. |
correlation between cortisol level and serotonin uptake in patients with chronic stress and depression. |
2003-01-30 |
2023-08-12 |
human |
| G E Tafet, V P Idoyaga-Vargas, D P Abulafia, J M Calandria, S S Roffman, A Chiovetta, M Shinitzk. Correlation between cortisol level and serotonin uptake in patients with chronic stress and depression. Cognitive, affective & behavioral neuroscience. vol 1. issue 4. 2003-01-30. PMID:12467090. |
a significant increase in serotonin uptake (+37% + 14, m + sd) was observed in the control group, whereas neither the generalized anxiety disorder nor the major depression group exhibited changes in serotonin uptake upon incubation with cortisol. |
2003-01-30 |
2023-08-12 |
human |
| G E Tafet, M Toister-Achituv, M Shinitzk. Enhancement of serotonin uptake by cortisol: a possible link between stress and depression. Cognitive, affective & behavioral neuroscience. vol 1. issue 1. 2003-01-30. PMID:12467107. |
enhancement of serotonin uptake by cortisol: a possible link between stress and depression. |
2003-01-30 |
2023-08-12 |
human |
| G E Tafet, M Toister-Achituv, M Shinitzk. Enhancement of serotonin uptake by cortisol: a possible link between stress and depression. Cognitive, affective & behavioral neuroscience. vol 1. issue 1. 2003-01-30. PMID:12467107. |
accordingly, the elevated cortisol induced by stress increases serotonin uptake, under both rest and nerve stimulation, which is overtly expressed in symptoms of depression. |
2003-01-30 |
2023-08-12 |
human |
| Jeffrey H Meyer, Shelley McMain, Sidney H Kennedy, Lorne Korman, Gregory M Brown, Jean N DaSilva, Alan A Wilson, Thomas Blak, Rahel Eynan-Harvey, Verdell S Goulding, Sylvain Houle, Paul Link. Dysfunctional attitudes and 5-HT2 receptors during depression and self-harm. The American journal of psychiatry. vol 160. issue 1. 2003-01-30. PMID:12505806. |
to investigate whether the converse, a low level of 5-ht agonism, could account for the higher levels of dysfunctional attitudes observed in patients with major depression or with self-injurious behavior, cortex 5-ht(2) receptor binding potential and dysfunctional attitudes were measured in patients with major depressive disorder, patients with a history of self-injurious behavior, and healthy comparison subjects (5-ht(2) receptor density increases during 5-ht depletion). |
2003-01-30 |
2023-08-12 |
human |
| Dorotea Mück-Seler, Nela Pivac, Marina Sagud, Miro Jakovljević, Alma Mihaljević-Pele. The effects of paroxetine and tianeptine on peripheral biochemical markers in major depression. Progress in neuro-psychopharmacology & biological psychiatry. vol 26. issue 7-8. 2003-01-27. PMID:12502009. |
depression is related to the alterations of the central serotonergic system and some antidepressants achieve their therapeutic effects through alteration of serotonin (5-ht) (re)uptake. |
2003-01-27 |
2023-08-12 |
Not clear |
| Dorotea Mück-Seler, Nela Pivac, Marina Sagud, Miro Jakovljević, Alma Mihaljević-Pele. The effects of paroxetine and tianeptine on peripheral biochemical markers in major depression. Progress in neuro-psychopharmacology & biological psychiatry. vol 26. issue 7-8. 2003-01-27. PMID:12502009. |
peripheral biochemical markers, platelet and serum 5-ht concentrations, platelet monoamine oxidase (mao) activity, plasma levels of cortisol and prolactin (prl), were investigated in patients with major depression before and after 4 weeks of treatment with paroxetine (an inhibitor of 5-ht uptake) or tianeptine (a stimulator of 5-ht uptake). |
2003-01-27 |
2023-08-12 |
Not clear |
| Patricia A Broderic. Interleukin 1alpha alters hippocampal serotonin and norepinephrine release during open-field behavior in Sprague-Dawley animals: differences from the Fawn-Hooded animal model of depression. Progress in neuro-psychopharmacology & biological psychiatry. vol 26. issue 7-8. 2003-01-27. PMID:12502025. |
interleukin 1alpha alters hippocampal serotonin and norepinephrine release during open-field behavior in sprague-dawley animals: differences from the fawn-hooded animal model of depression. |
2003-01-27 |
2023-08-12 |
human |
| Lynn Evans, Shahrokh Golshan, John Kelsoe, Mark Rapaport, Kathryn Resovsky, Laura Sutton, J Christian Gilli. Effects of rapid tryptophan depletion on sleep electroencephalogram and mood in subjects with partially remitted depression on bupropion. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology. vol 27. issue 6. 2003-01-24. PMID:12464458. |
other studies showed that the tfd increased rapid eye movement (rem) sleep in both normal males and in remitted depression patients on selective serotonin reuptake inhibitors (ssris) without affecting mood. |
2003-01-24 |
2023-08-12 |
human |
| Siegfried Kasper, Johannes Tauscher, Matthäus Willeit, Mara Stamenkovic, Alexander Neumeister, Bernd Küfferle, Christian Barnas, Jürgen Stastny, Nicole Praschak-Rieder, Lukas Pezawas, Martina de Zwaan, Sylvia Quiner, Walter Pirker, Susanne Asenbaum, Ivo Podreka, Thomas Brück. Receptor and transporter imaging studies in schizophrenia, depression, bulimia and Tourette's disorder--implications for psychopharmacology. The world journal of biological psychiatry : the official journal of the World Federation of Societies of Biological Psychiatry. vol 3. issue 3. 2003-01-23. PMID:12478878. |
striatal d2 and 5-ht1a receptors were studied in schizophrenia and 5-ht transporters (5-htt) in depression and bulimia. |
2003-01-23 |
2023-08-12 |
human |
| Siegfried Kasper, Johannes Tauscher, Matthäus Willeit, Mara Stamenkovic, Alexander Neumeister, Bernd Küfferle, Christian Barnas, Jürgen Stastny, Nicole Praschak-Rieder, Lukas Pezawas, Martina de Zwaan, Sylvia Quiner, Walter Pirker, Susanne Asenbaum, Ivo Podreka, Thomas Brück. Receptor and transporter imaging studies in schizophrenia, depression, bulimia and Tourette's disorder--implications for psychopharmacology. The world journal of biological psychiatry : the official journal of the World Federation of Societies of Biological Psychiatry. vol 3. issue 3. 2003-01-23. PMID:12478878. |
beta-cit as a ligand for measurement of 5-ht transporter densities (5-htt) revealed lower rates in depression compared to age- and sex-matching healthy controls, a measurement that has also been obtained for bulimia. |
2003-01-23 |
2023-08-12 |
human |