| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Ana Lúcia S Rodrigues, Gisele L da Silva, Andreza S Mateussi, Elizabeth S Fernandes, Obdulio G Miguel, Rosendo A Yunes, João B Calixto, Adair R S Santo. Involvement of monoaminergic system in the antidepressant-like effect of the hydroalcoholic extract of Siphocampylus verticillatus. Life sciences. vol 70. issue 12. 2002-03-22. PMID:11885577. |
the antidepressant-like effect of the hydroalcoholic extract obtained from aerial parts of siphocampylus verticillatus, a brazilian medicinal plant, was investigated in two models of depression in mice and against synaptosomal uptake of serotonin, noradrenaline and dopamine. |
2002-03-22 |
2023-08-12 |
mouse |
| Derek N Middlemiss, Gary W Price, Jeannette M Watso. Serotonergic targets in depression. Current opinion in pharmacology. vol 2. issue 1. 2002-03-20. PMID:11786304. |
serotonin reuptake inhibitors have proved to be a very effective treatment for depression and have strengthened the hypothesis that impaired 5-hydroxytryptamine (5-ht) neurotransmission may contribute to the underlying cause of depressive disorders. |
2002-03-20 |
2023-08-12 |
Not clear |
| Inmaculada Bellido, Zaida Díaz-Cabiale, Patricia A Jiménez-Vasquez, Beth Andbjer, Aleksander A Mathé, Kjell Fux. Increased density of galanin binding sites in the dorsal raphe in a genetic rat model of depression. Neuroscience letters. vol 317. issue 2. 2002-03-19. PMID:11755250. |
the results indicate that enhancement of galanin receptor function in the dorsal raphe rich in 5-ht neurons could be a mechanism involved in the production of depressive-like activity in this animal model of depression. |
2002-03-19 |
2023-08-12 |
rat |
| P J Cowe. Cortisol, serotonin and depression: all stressed out? The British journal of psychiatry : the journal of mental science. vol 180. 2002-03-19. PMID:11823315. |
cortisol, serotonin and depression: all stressed out? |
2002-03-19 |
2023-08-12 |
Not clear |
| S Aznar, G M Knudse. Serotonin induces a decrease of 5-HT(1A) immunoreactivity in organotypic hippocampal cultures. Neuroreport. vol 12. issue 18. 2002-03-18. PMID:11742209. |
serotonin reuptake inhibitors used for the treatment of depression act by increasing serotonin levels at the synaptic cleft and thereby activating 5-ht(1a) serotonin receptors. |
2002-03-18 |
2023-08-12 |
Not clear |
| Sunil Verma, Rollin M Gallaghe. The psychopharmacologic treatment of depression and anxiety in the context of chronic pain. Current pain and headache reports. vol 6. issue 1. 2002-03-07. PMID:11749875. |
selective serotonin reuptake inhibitors, tricyclics, and newer antidepressants effectively treat both depression and selected anxiety disorders. |
2002-03-07 |
2023-08-12 |
Not clear |
| B Arias, C Gastó, R Catalán, B Gutiérrez, L Pintor, L Fañaná. The 5-HT(2A) receptor gene 102T/C polymorphism is associated with suicidal behavior in depressed patients. American journal of medical genetics. vol 105. issue 8. 2002-03-05. PMID:11803534. |
the aim of this study was to investigate whether the proposed association between 5-ht(2a)-102t/c polymorphism and suicidality could be replicated in a larger and independent sample of spanish patients with major depression. |
2002-03-05 |
2023-08-12 |
human |
| B Arias, C Gastó, R Catalán, B Gutiérrez, L Pintor, L Fañaná. The 5-HT(2A) receptor gene 102T/C polymorphism is associated with suicidal behavior in depressed patients. American journal of medical genetics. vol 105. issue 8. 2002-03-05. PMID:11803534. |
the 102t/c polymorphism of the 5-ht(2a) receptor gene was analyzed in 159 patients with major depression (dsm-iv criteria) and 164 unrelated and healthy controls using a case control design. |
2002-03-05 |
2023-08-12 |
human |
| B Arias, C Gastó, R Catalán, B Gutiérrez, L Pintor, L Fañaná. The 5-HT(2A) receptor gene 102T/C polymorphism is associated with suicidal behavior in depressed patients. American journal of medical genetics. vol 105. issue 8. 2002-03-05. PMID:11803534. |
our results replicate the proposed association between 5ht(2a)-c allele and suicidality in major depression. |
2002-03-05 |
2023-08-12 |
human |
| B Arias, C Gastó, R Catalán, B Gutiérrez, L Pintor, L Fañaná. The 5-HT(2A) receptor gene 102T/C polymorphism is associated with suicidal behavior in depressed patients. American journal of medical genetics. vol 105. issue 8. 2002-03-05. PMID:11803534. |
moreover, no overall associations are detected when patients with major depression and controls are compared for 102t/c frequencies, suggesting that the increased risk for suicidality conferred by 5-ht(2a)-c allele is primarily associated with suicidal behavior and not with the diagnosis of major depression itself. |
2002-03-05 |
2023-08-12 |
human |
| B Lack, S Daya, T Nyokon. Interaction of serotonin and melatonin with sodium, potassium, calcium, lithium and aluminium. Journal of pineal research. vol 31. issue 2. 2002-03-04. PMID:11555164. |
the binding of serotonin to lithium could provide an explanation for the therapeutic effects of lithium in depression treatment, whereas the binding of aluminium by melatonin could provide insight into the role of this element in the aetiology of alzheimer's disease. |
2002-03-04 |
2023-08-12 |
Not clear |
| Sandra M Sanabria-Bohórquez, Francoise Biver, Philippe Damhaut, David Wikler, Claude Veraart, Serge Goldma. Quantification of 5-HT(1A) receptors in human brain using p-MPPF kinetic modelling and PET. European journal of nuclear medicine and molecular imaging. vol 29. issue 1. 2002-02-28. PMID:11807610. |
serotonin-1a (5-ht(1a)) receptors are implicated in neurochemical mechanisms underlying anxiety and depression and their treatment. |
2002-02-28 |
2023-08-12 |
human |
| W D Steers, K S Le. Depression and incontinence. World journal of urology. vol 19. issue 5. 2002-02-27. PMID:11760784. |
lowering monoamines such as serotonin and noradrenaline in the central nervous system (cns) leads to depression and urinary frequency and a hyperactive bladder in experimental animals. |
2002-02-27 |
2023-08-12 |
Not clear |
| E Wauban. [Therapeutic indications for managing symptoms: fatigue]. Revue neurologique. vol 157. issue 8-9 Pt 2. 2002-02-27. PMID:11787338. |
inhibitors of serotonin re-uptake are used pragmatically because of the relationship between fatigue and depression. |
2002-02-27 |
2023-08-12 |
Not clear |
| Alban Laurent, Jean-Marc Goaillard, Olivier Cases, Cecile Lebrand, Patricia Gaspar, Nicole Roper. Activity-dependent presynaptic effect of serotonin 1B receptors on the somatosensory thalamocortical transmission in neonatal mice. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 22. issue 3. 2002-02-27. PMID:11826118. |
in tc slices of postnatal day 5 (p5)-p9 neonate mice, we show that 5-ht reduces monosynaptic tc epscs evoked by low-frequency internal capsule stimulation and relieves the short-term depression of the epsc evoked by high-frequency stimulation. |
2002-02-27 |
2023-08-12 |
mouse |
| Alban Laurent, Jean-Marc Goaillard, Olivier Cases, Cecile Lebrand, Patricia Gaspar, Nicole Roper. Activity-dependent presynaptic effect of serotonin 1B receptors on the somatosensory thalamocortical transmission in neonatal mice. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 22. issue 3. 2002-02-27. PMID:11826118. |
we provide evidence that 5-ht decreases the presynaptic release of glutamate: 5-ht reduces similarly the ampa-kainate and nmda components and the paired pulse depression of tc epscs. |
2002-02-27 |
2023-08-12 |
mouse |
| A J Dunn, A H Swiergie. The reductions in sweetened milk intake induced by interleukin-1 and endotoxin are not prevented by chronic antidepressant treatment. Neuroimmunomodulation. vol 9. issue 3. 2002-02-21. PMID:11752890. |
il-1 and lps are known to affect cerebral neurotransmission involving norepinephrine and serotonin, both of which have been implicated in feeding behavior and in the pharmacotherapy of depression in man. |
2002-02-21 |
2023-08-12 |
mouse |
| Zubin Bhagwagar, Richard Whale, Philip J Cowe. State and trait abnormalities in serotonin function in major depression. The British journal of psychiatry : the journal of mental science. vol 180. 2002-02-21. PMID:11772847. |
state and trait abnormalities in serotonin function in major depression. |
2002-02-21 |
2023-08-12 |
Not clear |
| Zubin Bhagwagar, Richard Whale, Philip J Cowe. State and trait abnormalities in serotonin function in major depression. The British journal of psychiatry : the journal of mental science. vol 180. 2002-02-21. PMID:11772847. |
neuroendocrine studies of brain serotonin (5-ht) function in depression generally show evidence of impaired 5-ht function but it is disputed whether or not this impairment resolves with clinical recovery. |
2002-02-21 |
2023-08-12 |
Not clear |
| B H Mulsant, B G Pollock, R Nebes, M D Miller, R A Sweet, J Stack, P R Houck, S Bensasi, S Mazumdar, C F Reynold. A twelve-week, double-blind, randomized comparison of nortriptyline and paroxetine in older depressed inpatients and outpatients. The American journal of geriatric psychiatry : official journal of the American Association for Geriatric Psychiatry. vol 9. issue 4. 2002-02-14. PMID:11739067. |
selective serotonin reuptake inhibitors may be less efficacious than tricyclic antidepressants in the treatment of severe depression in older patients. |
2002-02-14 |
2023-08-12 |
Not clear |