| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Ana Salomé Correia, Nuno Val. Tryptophan Metabolism in Depression: A Narrative Review with a Focus on Serotonin and Kynurenine Pathways. International journal of molecular sciences. vol 23. issue 15. 2022-08-12. PMID:35955633. |
this amino acid can be metabolized in two important pathways in the context of depression: the serotonin and kynurenine pathways. |
2022-08-12 |
2023-08-14 |
human |
| Nina K Popova, Anton S Tsybko, Vladimir S Naumenk. The Implication of 5-HT Receptor Family Members in Aggression, Depression and Suicide: Similarity and Difference. International journal of molecular sciences. vol 23. issue 15. 2022-08-12. PMID:35955946. |
being different multifactorial forms of psychopathology, aggression, depression and suicidal behavior, which is considered to be violent aggression directed against the self, have principal neurobiological links: preclinical and clinical evidence associates depression, aggression and suicidal behavior with dysregulation in central serotonergic (5-ht) neurotransmission. |
2022-08-12 |
2023-08-14 |
Not clear |
| Nina K Popova, Anton S Tsybko, Vladimir S Naumenk. The Implication of 5-HT Receptor Family Members in Aggression, Depression and Suicide: Similarity and Difference. International journal of molecular sciences. vol 23. issue 15. 2022-08-12. PMID:35955946. |
the implication of different types of 5-ht receptors in the genetic and epigenetic mechanisms of aggression, depression and suicidality has been well recognized. |
2022-08-12 |
2023-08-14 |
Not clear |
| Feng Zhao, Hao Zhang, Peng Wang, Wenjie Cui, Kaiyong Xu, Dan Chen, Minghui Hu, Zifa Li, Xiwen Geng, Sheng We. Oxytocin and serotonin in the modulation of neural function: Neurobiological underpinnings of autism-related behavior. Frontiers in neuroscience. vol 16. 2022-08-08. PMID:35937893. |
the change of serotonin level also been reported affecting the development of brain and causes asd-like behavioral abnormalities, such as anxiety, depression like behavior, stereotyped behavior. |
2022-08-08 |
2023-08-14 |
Not clear |
| Xianjing Han, Yanchun Zhao, Chunhui Sun, Kunlun Li, Baoxiang Zhao, Junying Miao, Le S. Safrole oxide induced 5-HT neuron-like cell differentiation of bone marrow mesenchymal stem cells by elevating G9a. In vitro cellular & developmental biology. Animal. 2022-08-01. PMID:35913528. |
our findings provide a new clue for further investigating the gene control of bmsc differentiation into 5-ht neuron-like cells and provide a putative strategy for depression diseases therapies. |
2022-08-01 |
2023-08-14 |
Not clear |
| Jacqui Wis. "No convincing evidence" that depression is caused by low serotonin levels, say study authors. BMJ (Clinical research ed.). vol 378. 2022-07-19. PMID:35853814. |
"no convincing evidence" that depression is caused by low serotonin levels, say study authors. |
2022-07-19 |
2023-08-14 |
Not clear |
| Joanna Moncrieff, Ruth E Cooper, Tom Stockmann, Simone Amendola, Michael P Hengartner, Mark A Horowit. The serotonin theory of depression: a systematic umbrella review of the evidence. Molecular psychiatry. 2022-07-19. PMID:35854107. |
the serotonin theory of depression: a systematic umbrella review of the evidence. |
2022-07-19 |
2023-08-14 |
Not clear |
| Joanna Moncrieff, Ruth E Cooper, Tom Stockmann, Simone Amendola, Michael P Hengartner, Mark A Horowit. The serotonin theory of depression: a systematic umbrella review of the evidence. Molecular psychiatry. 2022-07-19. PMID:35854107. |
the serotonin hypothesis of depression is still influential. |
2022-07-19 |
2023-08-14 |
Not clear |
| Joanna Moncrieff, Ruth E Cooper, Tom Stockmann, Simone Amendola, Michael P Hengartner, Mark A Horowit. The serotonin theory of depression: a systematic umbrella review of the evidence. Molecular psychiatry. 2022-07-19. PMID:35854107. |
we aimed to synthesise and evaluate evidence on whether depression is associated with lowered serotonin concentration or activity in a systematic umbrella review of the principal relevant areas of research. |
2022-07-19 |
2023-08-14 |
Not clear |
| Sang-Seo Park, Tae-Woon Kim, Bo-Kyun Kim, Seong-Hyun Kim, Jong-Suk Park, Mal-Soon Shi. The effects of exercise and diet on mental status, insulin signaling pathway, and microbiome in obese mice. Journal of exercise rehabilitation. vol 18. issue 3. 2022-07-18. PMID:35846233. |
exercise and diet improved depression and anxiety status by increasing the insulin signaling pathway and promoting serotonin production. |
2022-07-18 |
2023-08-14 |
mouse |
| Weera Supronsinchai, Jan Hoffmann, Simon Akerman, Peter J Goadsb. KCl-induced repetitive cortical spreading depression inhibiting trigeminal neuronal firing is mediated by 5-HT Cephalalgia : an international journal of headache. 2022-07-14. PMID:35833238. |
kcl-induced repetitive cortical spreading depression inhibiting trigeminal neuronal firing is mediated by 5-ht we aimed to examine the effects of repetitive cortical spreading depression on the responses of nociceptive trigeminal neurons with dural afferents and characterize the role of 5-ht |
2022-07-14 |
2023-08-14 |
Not clear |
| Salvatore Iuso, Lucia Monacis, Luigi Nappi, Stefania Malerba, Giovanna D'Andrea, Mario Altamura, Maurizio Margaglione, Antonello Bellomo, Annamaria Petit. Associations Between Personality Traits, Perceived Stress and Depressive Symptoms in Gynecological Cancer Patients Characterized by the Short and Long Allele Variant of the 5-HTTLPR Genotype: Preliminary Results. Clinical neuropsychiatry. vol 19. issue 3. 2022-07-13. PMID:35821869. |
the study explored associations between personality traits, perceived stress and symptoms of depression in oncological patients characterized by the two variants of the serotonin transporter (5-httlpr) polymorphisms. |
2022-07-13 |
2023-08-14 |
Not clear |
| Kristin Köhler-Forsberg, Brice Ozenne, Søren V Larsen, Asbjørn S Poulsen, Elizabeth B Landman, Vibeke H Dam, Cheng-Teng Ip, Anders Jørgensen, Claus Svarer, Gitte M Knudsen, Vibe G Frokjaer, Martin B Jørgense. Concurrent anxiety in patients with major depression and cerebral serotonin 4 receptor binding. A NeuroPharm-1 study. Translational psychiatry. vol 12. issue 1. 2022-07-12. PMID:35821015. |
concurrent anxiety in patients with major depression and cerebral serotonin 4 receptor binding. |
2022-07-12 |
2023-08-14 |
Not clear |
| Mei-Li Wei, Shi-Min He, An-Qi Chen, Zi-Xuan Fan, Wei Liu, Ling Zhang, Shi-Jie Lv, Cheng-Zeng Qiu, Hui-Ru Liu, Mu-Xian Hao, Zong-Jun Yin, Da-Long Re. Fluoxetine modifies circadian rhythm by reducing melatonin content in zebrafish. Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie. vol 153. 2022-07-01. PMID:35777221. |
fluoxetine (flx), a selective serotonin reuptake inhibitor (ssri), increases the serotonin levels in the brain to treat depression. |
2022-07-01 |
2023-08-14 |
zebrafish |
| Vishal Bhatia, Ashwani K Dhingra, Rameshwar Dass, Bhawna Chopra, Kumar Guarv. Formulation Development and in-vitro Evaluation of Escitalopram Fast Dissolving Tablets. Central nervous system agents in medicinal chemistry. 2022-06-24. PMID:35748551. |
escitalopram, a selective serotonin reuptake inhibitor (ssri), acts by increasing the serotonin level in the brain and is used widely for the management of depression and anxiety disorders. |
2022-06-24 |
2023-08-14 |
Not clear |
| b' \\xc4\\xb0lker \\xc3\\x96zben, G\\xc3\\xbcliz \\xc5\\x9eenormanc\\xc4\\xb1, Onur Okan Demirci, \\xc3\\x96mer \\xc5\\x9eenormanc\\xc4\\xb. Associations of dysfunctional attitudes, ruminations and metacognitive beliefs about rumination with pharmacological treatment response in patients with first episode of major depression. International journal of psychiatry in clinical practice. 2022-06-24. PMID:35749699.' |
the aim of this study is to investigate whether treatment with selective serotonin reuptake inhibitors (ssri) has an effect on the ruminative response, ruminative beliefs and dysfunctional attitudes (da), and to evaluate the effects of pre-treatment dysfunctional attitudes and rumination levels on treatment response in individuals diagnosed with the first episode of major depression (md). |
2022-06-24 |
2023-08-14 |
Not clear |
| Jasmin Obermanns, Vera Flasbeck, Saskia Steinmann, Georg Juckel, Barbara Emon. Investigation of the Serotonergic Activity and the Serotonin Content in Serum and Platelet, and the Possible Role of the Serotonin Transporter in Patients with Depression. Behavioral sciences (Basel, Switzerland). vol 12. issue 6. 2022-06-23. PMID:35735388. |
investigation of the serotonergic activity and the serotonin content in serum and platelet, and the possible role of the serotonin transporter in patients with depression. |
2022-06-23 |
2023-08-14 |
human |
| Jasmin Obermanns, Vera Flasbeck, Saskia Steinmann, Georg Juckel, Barbara Emon. Investigation of the Serotonergic Activity and the Serotonin Content in Serum and Platelet, and the Possible Role of the Serotonin Transporter in Patients with Depression. Behavioral sciences (Basel, Switzerland). vol 12. issue 6. 2022-06-23. PMID:35735388. |
alterations in the serotonin transporter gene (5-httlpr), the serotonergic activity in the brain, and the content of serotonin (5-ht) have been related to depression and were examined separately by previous studies. |
2022-06-23 |
2023-08-14 |
human |
| Jasmin Obermanns, Vera Flasbeck, Saskia Steinmann, Georg Juckel, Barbara Emon. Investigation of the Serotonergic Activity and the Serotonin Content in Serum and Platelet, and the Possible Role of the Serotonin Transporter in Patients with Depression. Behavioral sciences (Basel, Switzerland). vol 12. issue 6. 2022-06-23. PMID:35735388. |
since the serotonergic activity, peripheral serotonin content, and 5-httlpr were unrelated, the results suggest independent alterations of central and peripheral serotonergic systems in depression. |
2022-06-23 |
2023-08-14 |
human |
| Jasmin Obermanns, Vera Flasbeck, Saskia Steinmann, Georg Juckel, Barbara Emon. Investigation of the Serotonergic Activity and the Serotonin Content in Serum and Platelet, and the Possible Role of the Serotonin Transporter in Patients with Depression. Behavioral sciences (Basel, Switzerland). vol 12. issue 6. 2022-06-23. PMID:35735388. |
furthermore, the applied medication seems to influence serum serotonin content in patients with depression. |
2022-06-23 |
2023-08-14 |
human |