| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Ji-Yu Zhao, Jing Yan, Hong-Yang Wang, Qing-Qing Liu, Tian-Sheng Zhang, Chong-Yao Ha. [Effect of wheat-grain moxibustion on the expression of 5-HT and cortisol in the serum, and MR and GR in the hippocampus in rats with hypothyroidism complicated with depression]. Zhongguo zhen jiu = Chinese acupuncture & moxibustion. vol 42. issue 5. 2022-05-11. PMID:35543943. |
to observe the effect of wheat-grain moxibustion on behavior, 5-hydroxytryptamine (5-ht) and cortisol in the serum, mineralocorticoid receptor (mr) and glucocorticoid receptor (gr) in the hippocampus in rats with hypothyroidism complicated with depression, and to explore the possible mechanism of wheat-grain moxibustion on improving depression in rats with hypothyroidism. |
2022-05-11 |
2023-08-13 |
rat |
| Dennis A Burke, Veronica A Alvare. Serotonin receptors contribute to dopamine depression of lateral inhibition in the nucleus accumbens. Cell reports. vol 39. issue 6. 2022-05-11. PMID:35545050. |
serotonin receptors contribute to dopamine depression of lateral inhibition in the nucleus accumbens. |
2022-05-11 |
2023-08-13 |
mouse |
| Dennis A Burke, Veronica A Alvare. Serotonin receptors contribute to dopamine depression of lateral inhibition in the nucleus accumbens. Cell reports. vol 39. issue 6. 2022-05-11. PMID:35545050. |
presynaptic serotonin 5-ht1b receptors are responsible for a significant component of dopamine-induced synaptic depression. |
2022-05-11 |
2023-08-13 |
mouse |
| Angharad N de Cates, Marieke A G Martens, Lucy C Wright, Cassandra D Gould van Praag, Liliana P Capitão, Daisy Gibson, Philip J Cowen, Catherine J Harmer, Susannah E Murph. The Effect of the 5-HT Frontiers in psychiatry. vol 13. 2022-05-02. PMID:35492722. |
the effect of the 5-ht depression is a common and often recurrent illness with significant negative impact on a global scale. |
2022-05-02 |
2023-08-13 |
Not clear |
| Haider Sarwar, Shafiya Imtiaz Rafiqi, Showkat Ahmad, Sruthi Jinna, Sawleha Arshi Khan, Tamanna Karim, Omar Qureshi, Zeeshan A Zahid, Jon D Elhai, Jason C Levine, Shazia J Naqvi, Juan C Jaume, Shahnawaz Ima. Hyperinsulinemia Associated Depression. Clinical medicine insights. Endocrinology and diabetes. vol 15. 2022-05-02. PMID:35494421. |
increased inflammatory cytokines have also been shown to disrupt neurotransmitter metabolism and synaptic plasticity which play a role in the development of depression via inhibiting serotonin, dopamine, melatonin, and glutamate signaling. |
2022-05-02 |
2023-08-13 |
Not clear |
| Qi Li, Wentao Zhao, Sha Liu, Yu Zhao, Weixing Pan, Xiao Wang, Zhifen Liu, Yong X. Partial resistance to citalopram in a Wistar-Kyoto rat model of depression: An evaluation using resting-state functional MRI and graph analysis. Journal of psychiatric research. vol 151. 2022-05-02. PMID:35500452. |
wistar-kyoto (wky) rats as an endogenous depression model partially lack a response to classic selective serotonin reuptake inhibitors (ssris). |
2022-05-02 |
2023-08-13 |
rat |
| Raj Desai, Haesuk Park, Joshua D Brown, Raj Mohandas, Steven M Smit. Norepinephrine reuptake inhibitors and risk of antihypertensive treatment intensification and major adverse cardiovascular events in patients with stable hypertension and depression. Pharmacotherapy. 2022-04-28. PMID:35478186. |
to compare the risk of antihypertensive treatment intensification (ti) and major adverse cardiovascular events (mace) with the initiation of serotonin norepinephrine reuptake inhibitors compared to selective serotonin reuptake inhibitors (ssris) in patients with stable hypertension and depression. |
2022-04-28 |
2023-08-13 |
Not clear |
| Sara Sophia Guedes Linhares, Ywlliane da Silva Rodrigues Meurer, Antonio Aquino, Diego Aquino Câmara, Luiz Eduardo Mateus Brandão, Aline Lima Dierschnabel, Felipe Porto Fiuza, Ramon Hypólito Lima, Rovena Clara Engelberth, Jeferson Souza Cavalcant. Effects of prenatal exposure to fluoxetine on circadian rhythmicity in the locomotor activity and neuropeptide Y and 5-HT expression in male and female adult Wistar rats. International journal of developmental neuroscience : the official journal of the International Society for Developmental Neuroscience. 2022-04-28. PMID:35481929. |
serotonin (5-ht) reuptake inhibitors, such as fluoxetine, are the most prescribed antidepressant for maternal depression. |
2022-04-28 |
2023-08-13 |
rat |
| Maya Amitai, Shaked Kaffman, Eitan Kroizer, Maya Lebow, Ido Magen, Noa Benaroya-Milshtein, Silvana Fennig, Abraham Weizman, Alan Apter, Alon Che. Neutrophil to-lymphocyte and platelet-to-lymphocyte ratios as biomarkers for suicidal behavior in children and adolescents with depression or anxiety treated with selective serotonin reuptake inhibitors. Brain, behavior, and immunity. 2022-04-26. PMID:35470013. |
neutrophil to-lymphocyte and platelet-to-lymphocyte ratios as biomarkers for suicidal behavior in children and adolescents with depression or anxiety treated with selective serotonin reuptake inhibitors. |
2022-04-26 |
2023-08-13 |
Not clear |
| Islam Mohammad Shehata, Waniyah Masood, Nouran Nemr, Alexandra Anderson, Kamal Bhusal, Amber N Edinoff, Elyse M Cornett, Adam M Kaye, Alan D Kay. The Possible Application of Ketamine in the Treatment of Depression in Alzheimer's Disease. Neurology international. vol 14. issue 2. 2022-04-25. PMID:35466206. |
the efficacy of conventional antidepressants to treat depression in ad is conflicting, especially regarding selective serotonin reuptake inhibitors (ssris). |
2022-04-25 |
2023-08-13 |
Not clear |
| Fitri Fareez Ramli, Philip J Cowen, Beata R Godlewsk. The Potential Use of Ebselen in Treatment-Resistant Depression. Pharmaceuticals (Basel, Switzerland). vol 15. issue 4. 2022-04-23. PMID:35455482. |
the antidepressant effects of lithium in treatment-resistant depression (trd) have been attributed to its ability to facilitate presynaptic serotonin activity; this suggests that ebselen might also have a therapeutic role in this condition. |
2022-04-23 |
2023-08-13 |
human |
| Yong Gu, Nanxin Zhang, Shujie Zhu, Shuanghui Lu, Huidi Jiang, Hui Zho. Estradiol reduced 5-HT reuptake by Downregulating the Gene Expression of Plasma Membrane Monoamine Transporter (PMAT, Slc29a4) through estrogen receptor β and the MAPK/ERK signaling pathway. European journal of pharmacology. 2022-04-10. PMID:35398393. |
estrogen deficiency-induced female depression is closely related to 5-hydroxytriptamine (5-ht) deficiency. |
2022-04-10 |
2023-08-13 |
Not clear |
| Hui Zhao, Meiqiong Jiang, Mingsan Mia. Pharmacological Study on Total Glycosides of Xiebai Protecting against Depression Model. Journal of healthcare engineering. vol 2022. 2022-04-08. PMID:35392144. |
changes of serotonin (5-ht), dopamine (da), norepinephrine (ne), serum corticosterone (cort), adrenocorticotropic hormone (acth), organ index, and histopathology in brain tissue, to explore the treatment and characteristics of total white glucosides in depression model, were prepared by different stimuli in 21 days. |
2022-04-08 |
2023-08-13 |
rat |
| Michael V Heinz, George D Price, Franklin Ruan, Robert J Klein, Matthew Nemesure, Aliza Lopez, Nicholas C Jacobso. Association of Selective Serotonin Reuptake Inhibitor Use With Abnormal Physical Movement Patterns as Detected Using a Piezoelectric Accelerometer and Deep Learning in a Nationally Representative Sample of Noninstitutionalized Persons in the US. JAMA network open. vol 5. issue 4. 2022-04-07. PMID:35389502. |
selective serotonin reuptake inhibitors (ssris) are a common first-line treatment for some psychiatric disorders, including depression and anxiety; although they are generally well tolerated, ssris have known adverse effects, including movement problems, sleep disruption, and gastrointestinal problems (eg, nausea and upset stomach). |
2022-04-07 |
2023-08-13 |
Not clear |
| Yu Han, Meng Zhang, Jiahui Duan, Leyi Li, Jinge Du, Hui Cheng, Sheng Zhang, Yanhui Zhai, Xinglan An, Qi Li, Xueming Zhang, Ziyi Li, Bo Tan. Maternal Prepregnancy 5-Hydroxytryptamine Exposure Affects the Early Development of the Fetus. Frontiers in physiology. vol 13. 2022-04-04. PMID:35370795. |
in recent decades, the increasing incidence of depression has contributed to an increase in the use of serotonergic drugs, such as antidepressants, which predisposes humans to serotonin syndrome. |
2022-04-04 |
2023-08-13 |
mouse |
| Rafael R Domingues, Milo C Wiltbank, Laura L Hernande. Pregnancy Complications and Neonatal Mortality in a Serotonin Transporter Null Mouse Model: Insight Into the Use of Selective Serotonin Reuptake Inhibitor During Pregnancy. Frontiers in medicine. vol 9. 2022-04-01. PMID:35360732. |
additionally, it suggests that the adverse pregnancy outcomes in women taking ssri during gestation might be due to altered serotonin transporter function caused by ssri independent of underlying depression. |
2022-04-01 |
2023-08-13 |
mouse |
| Aqeela Zahra, Le Du, Meng Jia, Muhammad Umar Butt, Qun Wang, Yunfu Wang, Jianping W. Prenatal exposure of citalopram elicits depression-like and anxiety-like behaviors and alteration of morphology and protein expression of medial prefrontal cortex in young adult mice. Journal of integrative neuroscience. vol 21. issue 2. 2022-04-01. PMID:35364649. |
treatment of major depression disorder with selective serotonin reuptake inhibitors (ssris), such as citalopram (ctm), during pregnancy effects on the neurological trajectory of the offspring and induces enduring consequences, notably emotional and cognitive impairment. |
2022-04-01 |
2023-08-13 |
mouse |
| Khushboo, Nikhat J Siddiqi, Maria de Lourdes Pereira, Bechan Sharm. Neuroanatomical, Biochemical, and Functional Modifications in Brain Induced by Treatment with Antidepressants. Molecular neurobiology. 2022-03-30. PMID:35352302. |
the pharmacological treatment of depression has been based on the pathophysiology of deficiency in monoamines, mainly serotonin and noradrenaline. |
2022-03-30 |
2023-08-13 |
Not clear |
| Ryuichi Ohta, Chiaki San. Serotonin Syndrome Triggered by Overuse of Caffeine and Complicated With Neuroleptic Malignant Syndrome: A Case Report. Cureus. vol 14. issue 2. 2022-03-29. PMID:35345760. |
in rare cases, serotonin syndrome may be triggered by nonmedicinal foods, such as coffee. the patient described in this case report was a 65-year-old woman with a past medical history of major depression and a diagnosis of parkinson's disease who presented to our medical center with chief complaints of nausea, vomiting, and drowsiness. |
2022-03-29 |
2023-08-13 |
Not clear |
| Ryuichi Ohta, Chiaki San. Serotonin Syndrome Triggered by Overuse of Caffeine and Complicated With Neuroleptic Malignant Syndrome: A Case Report. Cureus. vol 14. issue 2. 2022-03-29. PMID:35345760. |
patients with depression and parkinson's syndrome should be evaluated for associated comorbidities, particularly serotonin syndrome and neuroleptic malignant syndrome. |
2022-03-29 |
2023-08-13 |
Not clear |