| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Amrollah Ebrahimi, Elham Nasre Esfahan, Shahla Akuchekian, Razieh Izadi, Elham Shaneh, Behzad Mahak. A randomized clinical trial: Comparison of group acceptance and commitment therapy with drug on quality of life and depression in patients with obsessive-compulsive disorder. Journal of research in medical sciences : the official journal of Isfahan University of Medical Sciences. vol 27. 2022-03-28. PMID:35342452. |
the aim of this study was to evaluate and compare the effect of act and selective serotonin reuptake inhibitors (ssris) drugs on the severity of depression symptoms and quality of life (qol) in obsessive-compulsive patients. |
2022-03-28 |
2023-08-13 |
Not clear |
| Sharon Cabanu, Fuencisla Pilar-Cuéllar, Paula Zubakina, Eva Florensa-Zanuy, Júlia Senserrich, Adrian Newman-Tancredi, Albert Adel. Molecular Signaling Mechanisms for the Antidepressant Effects of NLX-101, a Selective Cortical 5-HT Pharmaceuticals (Basel, Switzerland). vol 15. issue 3. 2022-03-26. PMID:35337135. |
molecular signaling mechanisms for the antidepressant effects of nlx-101, a selective cortical 5-ht depression is the most prevalent of the mental illnesses and serotonin (5-hydroxytryptamine, 5-ht) is considered to be the major neurotransmitter involved in its etiology and treatment. |
2022-03-26 |
2023-08-13 |
Not clear |
| Yingying Wang, Xueman Chen, Qiaoyu Chen, Ning Zhou, Xin Wang, Alei Zhang, Kequan Chen, Pingkai Ouyan. Construction of cell factory capable of efficiently converting L-tryptophan into 5-hydroxytryptamine. Microbial cell factories. vol 21. issue 1. 2022-03-25. PMID:35331215. |
among, 5-ht is an inhibitory neurotransmitter with proven benefits for treating the symptoms of depression. |
2022-03-25 |
2023-08-13 |
Not clear |
| Suaad Nasrin, Mohammad Nazmul Islam, Mohammed Abu Tayab, Mst Samima Nasrin, Md Abu Bakar Siddique, Talha Bin Emran, A S M Ali Rez. Chemical profiles and pharmacological insights of Anisomeles indica Kuntze: An experimental chemico-biological interaction. Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie. vol 149. 2022-03-24. PMID:35325851. |
the binding assay showed that 4-dehydroxy-n-(4,5-methylenedioxy-2-nitrobenzylidene) tyramine interacts favorably with monoamine oxidase and serotonin and m3 muscarinic acetylcholine receptors, displaying good pharmacokinetic properties, which may mediate the effects of meoh-ai on depression and diarrhea. |
2022-03-24 |
2023-08-13 |
mouse |
| Bianca Auschra, Markus J Wilhelm, Claudia Husung, Josef Jenewein, Andreas J Flammer, Lena Jellesta. The use of serotonin reuptake inhibitors increases the risk of bleeding in patients with assist devices. BMC cardiovascular disorders. vol 22. issue 1. 2022-03-23. PMID:35317724. |
serotonin reuptake inhibitor (sri) antidepressants are widely used to treat depression in these patients, though they are attributed an increased risk of bleeding due to their modification of hemostasis. |
2022-03-23 |
2023-08-13 |
Not clear |
| Sheng Yu, Wen Li, Lingxue Tang, Xinxin Fan, Senbang Yao, Xiuqing Zhang, Ziran Bi, Huaidong Chen. Depression in breast cancer patients: Immunopathogenesis and immunotherapy. Cancer letters. 2022-03-21. PMID:35307487. |
dysfunction of immune cells and cytokines cause depression by affecting tryptophan metabolism, serotonin levels, and blood-brain barrier permeability. |
2022-03-21 |
2023-08-13 |
Not clear |
| Nikita Deo, Gregory Redpat. Serotonin Receptor and Transporter Endocytosis Is an Important Factor in the Cellular Basis of Depression and Anxiety. Frontiers in cellular neuroscience. vol 15. 2022-03-14. PMID:35280519. |
current treatments revolve around selective serotonin reuptake inhibitors (ssris), yet these drugs are only moderately effective at relieving depression. |
2022-03-14 |
2023-08-13 |
Not clear |
| Nikita Deo, Gregory Redpat. Serotonin Receptor and Transporter Endocytosis Is an Important Factor in the Cellular Basis of Depression and Anxiety. Frontiers in cellular neuroscience. vol 15. 2022-03-14. PMID:35280519. |
endocytosis, the process by which plasma membrane and extracellular constituents are internalized into the cell, plays a central role in the regulation of serotonin (5-hydroxytryptophan, 5-ht) signaling, ssri function and depression and anxiety pathogenesis. |
2022-03-14 |
2023-08-13 |
Not clear |
| Shawn Ziff, Benjamin Stern, Gregory Lewis, Maliha Majeed, Vasavi Rakesh Gorantl. Analysis of Psilocybin-Assisted Therapy in Medicine: A Narrative Review. Cureus. vol 14. issue 2. 2022-03-11. PMID:35273885. |
results from these trials have shown significant reductions in depression and anxiety when compared with a placebo, and one trial found no significant difference when compared to a routinely prescribed selective serotonin reuptake inhibitor (ssri). |
2022-03-11 |
2023-08-13 |
Not clear |
| Sarah Damanti, Giuseppe Alvise Ramirez, Valentina Da Prat, Ambra Bertola, Emanuela Manzo, Stefania Vadruccio, Moreno Tresoldi, Philipe de Souto Barreto, Yves Rollan. Selective serotonin reuptake inhibitors and fractures in older nursing home residents: Data from the INCUR study. Maturitas. vol 158. 2022-03-04. PMID:35241236. |
depression and selective serotonin reuptake inhibitors (ssri) reduce bone mass and increase fracture risk. |
2022-03-04 |
2023-08-13 |
human |
| Ludek Fiala, Jiri Lenz, Pavel Havelka, Vaclav Vetvick. Delayed ejaculation in men with depressive disorders. Andrologia. 2022-03-04. PMID:35243671. |
one of the causes of delayed ejaculation may be elevated prolactin levels, which may be increased by psychosocial stress, pituitary disorders or also treatment with selective serotonin reuptake inhibitors in the treatment of depression. |
2022-03-04 |
2023-08-13 |
Not clear |
| Zubeyde Ercan, Meryem Sedef Dogru, Nazife Ulker Ertugrul, Ahmet Yardimci, Sinan Canpola. Beneficial effects of irisin in experimental paroxetine-induced hyperprolactinemia. Endocrine. 2022-02-28. PMID:35226247. |
it is known that selective serotonin reuptake inhibitors (ssris), represent an important and effective treatment of depression and other psychological disorders, these medications can increase prolactin levels mainly through activation of the serotonergic pathway. |
2022-02-28 |
2023-08-13 |
Not clear |
| Qiliang Chen, Candong Li, Enxiang Tao, Tetsuya Asakawa, Yuanyuan Zhan. Exploration of a Brain-Liver-Communication-Related Mechanism Involved in the Experimental Perimenopausal Depression Rat Model using Chaihu-Shugan-San. Neurochemical research. 2022-02-22. PMID:35190952. |
we observed the behavioural performances of depression and anxiety, serum concentrations of biochemical indices, serum estrogen two levels, hippocampal 5-ht and ne levels and the morphological changes in liver tissues. |
2022-02-22 |
2023-08-13 |
rat |
| Ying-Xiao Li, Kai-Chun Cheng, Chao-Tien Hsu, Juei-Tang Cheng, Ting-Ting Yan. Major Plant in Herbal Mixture Gan-Mai-Da-Zao for the Alleviation of Depression in Rat Models. Plants (Basel, Switzerland). vol 11. issue 3. 2022-02-15. PMID:35161241. |
the expression levels of the serotonin transporter (5-htt) and brain-derived neurotrophic factor (bdnf) in the hippocampus of the rats with depression were markedly increased by gmdz. |
2022-02-15 |
2023-08-13 |
rat |
| Xiao-Bo Yang, Heng-Bing Zu, Yong-Fei Zhao, Kai Ya. Agomelatine Prevents Amyloid Plaque Deposition, Tau Phosphorylation, and Neuroinflammation in APP/PS1 Mice. Frontiers in aging neuroscience. vol 13. 2022-02-14. PMID:35153715. |
agomelatine, an agonist of melatonergic mt1 and mt2 receptors and a selective 5-hydroxytryptamine 2c receptor antagonist, is widely applied in treating depression and insomnia symptoms in several neurogenerative diseases. |
2022-02-14 |
2023-08-13 |
mouse |
| Kaiping Burrows, Danielle C DeVille, Kelly T Cosgrove, Rayus T Kuplicki, Martin P Paulus, Robin Aupperle, Sahib S Khalsa, Jennifer L Stewar. Impact of serotonergic medication on interoception in major depressive disorder. Biological psychology. 2022-02-12. PMID:35149138. |
47 selective serotonin reuptake inhibitor (ssri)-medicated mdd (mdd-ssri) individuals were propensity-matched with 48 unmedicated current mdd (mdd-unmed) and 41 healthy comparison (hc) participants on demographics including age, sex, body mass index, education, as well as on dimensional scales of symptom severity including depression and anxiety. |
2022-02-12 |
2023-08-13 |
human |
| Youying Zhang, Qilin Fan, Yuanlong Hou, Xuanshuang Zhang, Zhe Yin, Xiaoying Cai, Wei Wei, Jiaying Wang, Dandan He, Guangji Wang, Yonggui Yuan, Haiping Hao, Xiao Zhen. Bacteroides Species Differentially Modulate Depression-Like Behavior via Gut-Brain Metabolic Signaling. Brain, behavior, and immunity. 2022-02-10. PMID:35143877. |
notably, an intensified depletion of cerebral serotonin concurred with the enhanced susceptibility to depression. |
2022-02-10 |
2023-08-13 |
mouse |
| Yuan-Yuan Chen, Ya-Hui Jin, Aerduosi Shayiranbieke, Xue Zhao, Hu-Shuai Fan, Qian Li, Xin-Feng Zha. Preparation and characterization of immobilized 5-HT Journal of pharmaceutical and biomedical analysis. vol 211. 2022-02-08. PMID:35131672. |
preparation and characterization of immobilized 5-ht the incidence of depression has increased significantly during the covid-19 pandemic. |
2022-02-08 |
2023-08-13 |
Not clear |
| Nicole Mariani, James Everson, Carmine M Pariante, Alessandra Borsin. Modulation of microglial activation by antidepressants. Journal of psychopharmacology (Oxford, England). 2022-01-31. PMID:35098788. |
antidepressants, including selective serotonin re-uptake inhibitors and serotonin-norepinephrine reuptake inhibitors, have been shown to act on the immune and oxidative stress mechanisms commonly found to be disrupted in depression. |
2022-01-31 |
2023-08-13 |
Not clear |
| Ana Paula Farias Waltrick, Alvaro Henrique Bernardo de Lima Silva, Milene Cristina de Carvalho, Bruna Aparecida Comotti de Oliveira, Katya Naliwaiko, Joice Maria da Cunha, Janaina Menezes Zanovel. Preventive treatment with fish oil facilitates the antidepressant-like effect of antidepressant drugs in type-1 diabetes mellitus rats: implication of serotonergic system. Neuroscience letters. 2022-01-29. PMID:35090949. |
in conclusion, ours results pointed out that the choice of the dha/epa ratio may be an important factor to be considered for the fo antidepressant-like effectper se,but the fo treatment in this composition associated with the antidepressant drugs - especially that ones that increase preferentially the availability of 5-ht -, may represent a better alternative of treatment to individuals with t1dm-associated depression. |
2022-01-29 |
2023-08-13 |
rat |