| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Soichiro Kitamura, Yasuyuki Kimura, Keisuke Takahata, Sho Moriguchi, Manabu Kubota, Hitoshi Shimada, Hironobu Endo, Yuhei Takado, Kazunori Kawamura, Ming-Rong Zhang, Tetsuya Suhara, Makoto Higuch. Serotonergic neurotransmission in limbic regions may reflect therapeutic response of depressive patients: A PET study with 11C-WAY-100635 and 18F-MPPF. The international journal of neuropsychopharmacology. 2023-06-06. PMID:37279545. |
central serotonin (5-hydroxytryptamine, 5-ht) neurotransmission has been implicated in the etiology of depression. |
2023-06-06 |
2023-08-14 |
Not clear |
| Dilpreet Singh, G D Gupt. A Complete Sojourn of Gene Therapy Along with its Targeting Approaches for the Treatment of the Major Depressive Disorder. Current gene therapy. 2023-06-02. PMID:37264624. |
depression has been linked to the malfunctioning of serotonin signaling genes, including p11, sert, etc, according to earlier research. |
2023-06-02 |
2023-08-14 |
Not clear |
| Mark Slifstein, Anissa Abi-Dargha. Detecting Pharmacologically Induced Serotonin Release in Depression With Positron Emission Tomography Imaging: A New Approach. Biological psychiatry. vol 93. issue 12. 2023-05-31. PMID:37257982. |
detecting pharmacologically induced serotonin release in depression with positron emission tomography imaging: a new approach. |
2023-05-31 |
2023-08-14 |
Not clear |
| Jinli Zhang, Xiaohui Zheng, Zhenying Zha. A systematic review and meta-analysis on the efficacy outcomes of selective serotonin reuptake inhibitors in depression in Alzheimer's disease. BMC neurology. vol 23. issue 1. 2023-05-31. PMID:37259037. |
a systematic review and meta-analysis on the efficacy outcomes of selective serotonin reuptake inhibitors in depression in alzheimer's disease. |
2023-05-31 |
2023-08-14 |
Not clear |
| S M Nageeb Hasan, Courtney Leigh Clarke, Tadhg Patrick McManamon Strand, Francis Rodriguez Bambic. Putative pathological mechanisms of late-life depression and Alzheimer's Disease. Brain research. 2023-05-27. PMID:37244602. |
ad and depression share common pathophysiologies, including functional deficits of the serotonin (5-ht) system. |
2023-05-27 |
2023-08-14 |
Not clear |
| Huijuan Liao, David S Rosenthal, Salini C Kuma. Abnormal Thyroid Function Laboratory Results Caused by Selective Serotonin Reuptake Inhibitor (SSRI) Antidepressant Treatment. Case reports in psychiatry. vol 2023. 2023-05-23. PMID:37215167. |
selective serotonin reuptake inhibitors (ssris) are often prescribed for depression. |
2023-05-23 |
2023-08-14 |
Not clear |
| Shatha Subhi ALHarthi, Munerah S BinShabaib, Abdulrahman Alwahibi, Shahinaz Gamal, Eldin Elashiry, Sarah E Almershed, Haifa Abdulrahman Alkhamis, Lamyia Anweig. Periodontal and peri-implant status and whole salivary interleukin 1-beta levels among individuals using selective serotonin reuptake inhibitors: an observational study. BMC oral health. vol 23. issue 1. 2023-05-22. PMID:37217913. |
selective serotonin reuptake inhibitors (ssri) are commonly used for managing psychological diseases such as depression. |
2023-05-22 |
2023-08-14 |
human |
| Makoto Kond. Molecular Mechanisms of Exercise-induced Hippocampal Neurogenesis and Antidepressant Effects. JMA journal. vol 6. issue 2. 2023-05-14. PMID:37179732. |
it has been reported that exercise has preventive effects on depression (antidepressant effects) and that serotonin, whose release increases in the brain with exercise, is involved in exercise-induced antidepressant effects. |
2023-05-14 |
2023-08-14 |
mouse |
| Arzoo Pannu, Ramesh K Goya. Serotonin and Depression: Scrutiny of New Targets for Future Anti-Depressant Drug Development. Current drug targets. 2023-05-12. PMID:37170981. |
serotonin and depression: scrutiny of new targets for future anti-depressant drug development. |
2023-05-12 |
2023-08-14 |
Not clear |
| Arzoo Pannu, Ramesh K Goya. Serotonin and Depression: Scrutiny of New Targets for Future Anti-Depressant Drug Development. Current drug targets. 2023-05-12. PMID:37170981. |
the "serotonin hypothesis of depression" is approximately fifty years old, and in spite of vast literature, the exact role of serotonin in depression pathophysiology is still unclear, as whether a lower serotonin level causes depression or depression causes a reduction in serotonin level has become a tough challenge for researchers to understand the actual involvement of serotonin in depression. |
2023-05-12 |
2023-08-14 |
Not clear |
| Arzoo Pannu, Ramesh K Goya. Serotonin and Depression: Scrutiny of New Targets for Future Anti-Depressant Drug Development. Current drug targets. 2023-05-12. PMID:37170981. |
several pre-clinical and clinical studies have illustrated the multi-faceted signalling action of serotonin in depression and vouch for the significant or unavoidable role of serotonin in depression. |
2023-05-12 |
2023-08-14 |
Not clear |
| Arzoo Pannu, Ramesh K Goya. Serotonin and Depression: Scrutiny of New Targets for Future Anti-Depressant Drug Development. Current drug targets. 2023-05-12. PMID:37170981. |
in this review, the journey of the serotonin hypothesis of depression from the 1950s to the present time has been analysed to understand the serotonin hypothesis of depression and investigate the new molecular targets for the development of new future anti- depressants. |
2023-05-12 |
2023-08-14 |
Not clear |
| Arzoo Pannu, Ramesh K Goya. Serotonin and Depression: Scrutiny of New Targets for Future Anti-Depressant Drug Development. Current drug targets. 2023-05-12. PMID:37170981. |
the old and new theories of possible cellular mechanisms found to be involved in the pathophysiology of major depression or stress, such as polymorphism of serotonin transporters, enzyme modulating serotonergic activity, reduction in the level of serotonin and involvement of different sub-types of receptors, have been discussed in the respective review. |
2023-05-12 |
2023-08-14 |
Not clear |
| Hua Min, Farrokh Alemi, Janusz Wojtusia. Selecting Antidepressants Based on Medical History and Stress Mechanism. Cureus. vol 15. issue 4. 2023-05-11. PMID:37168173. |
conclusions many studies have raised doubt about the serotonin hypothesis as the central mechanism for depression treatment. |
2023-05-11 |
2023-08-14 |
Not clear |
| Hua Min, Farrokh Alemi, Janusz Wojtusia. Selecting Antidepressants Based on Medical History and Stress Mechanism. Cureus. vol 15. issue 4. 2023-05-11. PMID:37168173. |
the identification of a wide range of predictors for prescribing antidepressants highlights the complexity of depression treatment and the need for individualized approaches that consider patients' comorbidities and previous treatments. the significant impact of comorbidities on the response to treatment makes it improbable that the mechanism of action of antidepressants is solely based on the serotonin hypothesis. |
2023-05-11 |
2023-08-14 |
Not clear |
| Shun Hao, Wantong Shi, Weiqi Liu, Qi-Yu Chen, Min Zhu. Multiple modulatory roles of serotonin in chronic pain and injury-related anxiety. Frontiers in synaptic neuroscience. vol 15. 2023-05-05. PMID:37143481. |
serotonin (5-ht) in the central nervous system (cns) has been recognized as an important neurotransmitter and neuromodulator which regulates various physiological functions, such as pain sensation, cognition, and emotions-especially anxiety and depression. |
2023-05-05 |
2023-08-14 |
Not clear |
| Patrizia Ambrogini, Davide Lattanzi, Marica Pagliarini, Michael Di Palma, Stefano Sartini, Riccardo Cuppini, Kjell Fuxe, Dasiel Oscar Borroto-Escuel. 5HT1AR-FGFR1 Heteroreceptor Complexes Differently Modulate GIRK Currents in the Dorsal Hippocampus and the Dorsal Raphe Serotonin Nucleus of Control Rats and of a Genetic Rat Model of Depression. International journal of molecular sciences. vol 24. issue 8. 2023-04-28. PMID:37108630. |
5ht1ar-fgfr1 heteroreceptor complexes differently modulate girk currents in the dorsal hippocampus and the dorsal raphe serotonin nucleus of control rats and of a genetic rat model of depression. |
2023-04-28 |
2023-08-14 |
rat |
| Hannah P Fricke, Laura L Hernande. The Serotonergic System and Bone Metabolism During Pregnancy and Lactation and the Implications of SSRI Use on the Maternal-Offspring Dyad. Journal of mammary gland biology and neoplasia. vol 28. issue 1. 2023-04-22. PMID:37086330. |
it is estimated that postpartum depression affects 10-15% of the population, and selective serotonin reuptake inhibitors (ssri) are often used as the first-line treatment. |
2023-04-22 |
2023-08-14 |
human |
| Chungsoo Kim, Dong Yun Lee, Jimyung Park, Su-Jin Yang, Eng Hooi Tan, Daniel-Prieto Alhambra, Yo Han Lee, Sangha Lee, Seong-Ju Kim, Jeewon Lee, Rae Woong Park, Yunmi Shi. Safety Outcomes of Selective Serotonin Reuptake Inhibitors in Adolescent Attention-Deficit/Hyperactivity Disorder with Comorbid Depression: The ASSURE Study - CORRIGENDUM. Psychological medicine. 2023-04-20. PMID:37078398. |
safety outcomes of selective serotonin reuptake inhibitors in adolescent attention-deficit/hyperactivity disorder with comorbid depression: the assure study - corrigendum. |
2023-04-20 |
2023-08-14 |
Not clear |
| Han Zhao, Yue Yin, Tong Lin, Wushuang Wang, Lan Gon. Administration of serotonin and norepinephrine reuptake inhibitors tends to have less ocular surface damage in a chronic stress-induced rat model of depression than selective serotonin reuptake inhibitors. Experimental eye research. 2023-04-20. PMID:37080380. |
administration of serotonin and norepinephrine reuptake inhibitors tends to have less ocular surface damage in a chronic stress-induced rat model of depression than selective serotonin reuptake inhibitors. |
2023-04-20 |
2023-08-14 |
human |