| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Ofelia Limón-Morales, Kenia Morales-Quintero, Marcela Arteaga-Silva, Tania Molina-Jiménez, Marco Cerbón, Herlinda Bonilla-Jaim. Alterations of learning and memory are accompanied by alterations in the expression of 5-HT receptors, glucocorticoid receptor and brain-derived neurotrophic factor in different brain regions of an animal model of depression generated by neonatally male treatment with clomipramine in male rats. Behavioural brain research. 2023-09-15. PMID:37714467. |
alterations of learning and memory are accompanied by alterations in the expression of 5-ht receptors, glucocorticoid receptor and brain-derived neurotrophic factor in different brain regions of an animal model of depression generated by neonatally male treatment with clomipramine in male rats. |
2023-09-15 |
2023-10-07 |
rat |
| Nikolas Ros. Commentary: Recent disputes on the role of serotonin in depression. Psychological medicine. 2023-09-12. PMID:37698506. |
commentary: recent disputes on the role of serotonin in depression. |
2023-09-12 |
2023-10-07 |
Not clear |
| Scotti McLaren, Karin Seidler, James Nei. Investigating the Role of 17β-Estradiol on the Serotonergic System, Targeting Soy Isoflavones as a Strategy to Reduce Menopausal Depression: A Mechanistic Review. Journal of the American Nutrition Association. 2023-09-11. PMID:37695875. |
low serotonin is one factor implicated in the development of depression. |
2023-09-11 |
2023-10-07 |
human |
| Naoto Kajitani, Mami Okada-Tsuchioka, Asuka Inoue, Kanako Miyano, Takeshi Masuda, Shuken Boku, Kazuya Iwamoto, Sumio Ohtsuki, Yasuhito Uezono, Junken Aoki, Minoru Takebayash. G protein-biased LPAR1 agonism of prototypic antidepressants: Implication in the identification of novel therapeutic target for depression. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology. 2023-09-06. PMID:37673966. |
prototypic antidepressants, such as tricyclic/tetracyclic antidepressants (tcas), have multiple pharmacological properties and have been considered to be more effective than newer antidepressants, such as selective serotonin reuptake inhibitors, in treating severe depression. |
2023-09-06 |
2023-10-07 |
mouse |
| Michael Frazure, In Morimoto, Nathan Fielder, Nicholas Mellen, Kimberly Iceman, Teresa Pitt. Serotonin therapies for opioid-induced dysphagia and respiratory depression: sex differences in a rat electromyography model. bioRxiv : the preprint server for biology. 2023-09-04. PMID:37662371. |
serotonin therapies for opioid-induced dysphagia and respiratory depression: sex differences in a rat electromyography model. |
2023-09-04 |
2023-09-07 |
rat |
| Joanna Witoszyńska-Sobkowiak, Dorota Sikorska, Rafał Rutkowski, Karolina Niklas, Iwona Żychowska, Włodzimierz Samborsk. Treatment of ankylosing spondylitis with TNFα inhibitors does not affect serum levels of tryptophan metabolites. Inflammopharmacology. 2023-08-30. PMID:37646896. |
the imbalance between the kynurenine and serotonin pathways can have serious consequences, e.g., depression. |
2023-08-30 |
2023-09-07 |
human |
| Chaoyu Liu, Eivind Ystrom, Tom A McAdam. Long-Term Maternal and Child Outcomes Following Postnatal SSRI Treatment. JAMA network open. vol 6. issue 8. 2023-08-29. PMID:37642961. |
although selective serotonin reuptake inhibitors (ssris) are recommended for postnatal depression treatment, there is a lack of evidence regarding long-term maternal and child outcomes following postnatal ssri treatment. |
2023-08-29 |
2023-09-07 |
Not clear |
| Yuki Higuchi, Hiroyuki Arakaw. Serotonergic mediation of the brain-wide neurogenesis: Region-dependent and receptor-type specific roles on neurogenic cellular transformation. Current research in neurobiology. vol 5. 2023-08-28. PMID:37638344. |
highlighting these 5-ht mechanisms that mediate neurogenic cell production processes in a brain-region-specific manner would provide unique insights into the role of 5-ht in neurogenesis and its associated effects on depression. |
2023-08-28 |
2023-09-07 |
Not clear |
| Efthalia Angelopoulou, Evangelia Stanitsa, Claire Chrysanthi Karpodini, Anastasia Bougea, Dionysia Kontaxopoulou, Stella Fragkiadaki, Christos Koros, Vasiliki Epameinondas Georgakopoulou, George Fotakopoulos, Yiannis Koutedakis, Christina Piperi, Sokratis G Papageorgio. Pharmacological and Non-Pharmacological Treatments for Depression in Parkinson's Disease: An Updated Review. Medicina (Kaunas, Lithuania). vol 59. issue 8. 2023-08-26. PMID:37629744. |
available pharmacological therapeutic options for depression in pd mainly include selective serotonin reuptake inhibitors, serotonin and norepinephrine reuptake inhibitors, and tricyclic antidepressants; meanwhile, agents acting on dopaminergic pathways used for motor symptoms, such as levodopa, dopaminergic agonists, and monoamine oxidase b (mao-b) inhibitors, may also provide beneficial antidepressant effects. |
2023-08-26 |
2023-09-07 |
Not clear |
| Yasmine Rifai, Nicholas Cassimatis, Bruce Rubenstein M . Depression in Patients With Intracranial Hemorrhage Secondary to Traumatic Brain Injury. Cureus. vol 15. issue 7. 2023-08-21. PMID:37602011. |
this article discusses the prevalence of depression in patients with intracranial hemorrhage (ich) and the relationship of selective serotonin reuptake inhibitor (ssri) use with bleeding risk. |
2023-08-21 |
2023-09-07 |
Not clear |
| Khalid AlHezaimi, Ilan Rotstein, Joseph Katz, Marc Nevins, Myron Nevin. Effect of selective serotonin reuptake inhibitor (paroxetine) on newly formed bone volume: Real time in vivo micro computed tomographic analysis. Journal of endodontics. 2023-08-18. PMID:37595681. |
selective serotonin reuptake inhibitors (ssris) antidepressant are commonly used to treat depression and anxiety. |
2023-08-18 |
2023-10-07 |
Not clear |
| Xiao-Lan Yu, Cui-Ping Li, Lian-Ping H. Vitamin D may alleviate irritable bowel syndrome by modulating serotonin synthesis: a hypothesis based on recent literature. Frontiers in physiology. vol 14. 2023-08-14. PMID:37576336. |
a number of studies found that serotonin plays a vital role in the development of depression and irritable bowel syndrome. |
2023-08-14 |
2023-08-16 |
Not clear |
| Vasileia Kotoula, Jennifer W Evans, Claire E Punturieri, Carlos A Zarat. Review: The use of functional magnetic resonance imaging (fMRI) in clinical trials and experimental research studies for depression. Frontiers in neuroimaging. vol 2. 2023-08-09. PMID:37554642. |
our search results focused on selective serotonin reuptake inhibitors (ssris), the most commonly prescribed treatments for depression and ketamine, a fast-acting antidepressant treatment. |
2023-08-09 |
2023-08-16 |
Not clear |
| Neda H Bidoki, Kristy A Zera, Huda Nassar, Lauren L Drag, Michael Mlynash, Elizabeth Osborn, Muhith Musabbir, Da Eun K Kim, Maria Paula Mendez, Maarten G Lansberg, Nima Aghaeepour, Marion S Buckwalte. Machine learning models of plasma proteomic data predict mood in chronic stroke and tie it to aberrant peripheral immune responses. Brain, behavior, and immunity. 2023-08-09. PMID:37557961. |
we propose that in chronic post-stroke depression there is over-activation of the immune response that then triggers changes in serotonin activity and neuronal plasticity leading to depressed mood. |
2023-08-09 |
2023-08-16 |
human |
| Sandrita Simonyte, Ingrida Grabauskyte, Jurate Macijauskiene, Vita Lesauskaite, Vaiva Lesauskaite, Kari Sofie Kvaal, Robert Stewar. Associations of the serotonin transporter gene polymorphism, 5-HTTLPR, and adverse life events with late life depression in the elderly Lithuanian population. Scientific reports. vol 13. issue 1. 2023-08-09. PMID:37558806. |
associations of the serotonin transporter gene polymorphism, 5-httlpr, and adverse life events with late life depression in the elderly lithuanian population. |
2023-08-09 |
2023-08-16 |
human |
| Chen-Cheng Lin, Chiu-Ping Yang, Pao-Yun Cheng, Michael Hsiao, Yia-Ping Li. Escitalopram reversibility of the impacts following chronic stress on central 5-HT profiles - Implications to depression and anxiety. Behavioural brain research. 2023-08-06. PMID:37544369. |
escitalopram reversibility of the impacts following chronic stress on central 5-ht profiles - implications to depression and anxiety. |
2023-08-06 |
2023-08-14 |
rat |
| Chen-Cheng Lin, Chiu-Ping Yang, Pao-Yun Cheng, Michael Hsiao, Yia-Ping Li. Escitalopram reversibility of the impacts following chronic stress on central 5-HT profiles - Implications to depression and anxiety. Behavioural brain research. 2023-08-06. PMID:37544369. |
later studies suggest both presynaptic and postsynaptic 5-ht profiles should be considered for the effects of ssris, making it difficult to interpret the etiological and therapeutic mechanisms underlying depression and anxiety. |
2023-08-06 |
2023-08-14 |
rat |
| Kyung Hwa Lee, Jiyoon Shin, Jung Lee, Jae Hyun Yoo, Jae-Won Kim, David A Bren. Measures of Connectivity and Dorsolateral Prefrontal Cortex Volumes and Depressive Symptoms Following Treatment With Selective Serotonin Reuptake Inhibitors in Adolescents. JAMA network open. vol 6. issue 8. 2023-08-04. PMID:37540512. |
selective serotonin reuptake inhibitors (ssris) are considered a first-line pharmacological treatment for adolescent depression with moderate or higher levels of symptom severity. |
2023-08-04 |
2023-08-14 |
Not clear |
| Shengyuan Wang, Shaohui Li, Heng Wu, Tongyangzi Zhang, Yixiao Chen, Yiqing Zhu, Siwan Wen, Cuiqin Shi, Li Yu, Xianghuai X. A randomized, double-blinded, placebo-controlled clinical trial of duloxetine hydrochloride enteric-coated tablets in the treatment of refractory chronic cough. BMC pulmonary medicine. vol 23. issue 1. 2023-08-02. PMID:37533019. |
this trail proposes using duloxetine, a selective 5-ht and norepinephrine reuptake inhibitor, as a potential treatment for refractory cough, which has shown promise in treating pain and depression. |
2023-08-02 |
2023-08-14 |
Not clear |
| Tyra Lagerberg, Anthony A Matthews, Nanbo Zhu, Seena Fazel, Juan-Jesus Carrero, Zheng Chan. Effect of selective serotonin reuptake inhibitor treatment following diagnosis of depression on suicidal behaviour risk: a target trial emulation. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology. 2023-07-28. PMID:37507510. |
effect of selective serotonin reuptake inhibitor treatment following diagnosis of depression on suicidal behaviour risk: a target trial emulation. |
2023-07-28 |
2023-08-14 |
Not clear |