| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| R Kanjhan, G D Housley, L D Burton, D L Christie, A Kippenberger, P R Thorne, L Luo, A F Rya. Distribution of the P2X2 receptor subunit of the ATP-gated ion channels in the rat central nervous system. The Journal of comparative neurology. vol 407. issue 1. 1999-06-21. PMID:10213185. |
these data support the role for extracellular atp acting as a fast neurotransmitter at pre- and postsynaptic sites in processes such as sensory transmission, sensory-motor integration, motor and autonomic control, and in neuronal phenomena such as long-term potentiation (ltp) and depression (ltd). |
1999-06-21 |
2023-08-12 |
rat |
| R Bourdeaux, P Pannetier, D Desor, P R Lehr, C Younos, B Capolagh. [Effect of fluoxetine treatment on serotonin and MHPG in 32 patients with major depressive disorder]. L'Encephale. vol 25. issue 1. 1999-06-17. PMID:10205732. |
considering the concept that depressive disorders were not only resulting from activity of one neurotransmitter, possible interactions between the noradrenergic system and a selective serotonin uptake inhibitor, fluoxetine, were investigated in order to test the hypothesis of noradrenergic or serotonergic involvement in depression. |
1999-06-17 |
2023-08-12 |
human |
| A A Genazzani, E Carafoli, D Guerin. Calcineurin controls inositol 1,4,5-trisphosphate type 1 receptor expression in neurons. Proceedings of the National Academy of Sciences of the United States of America. vol 96. issue 10. 1999-06-17. PMID:10318964. |
in the central nervous system, release of ca2+ from intracellular stores contributes to numerous functions, including neurotransmitter release and long-term potentiation and depression. |
1999-06-17 |
2023-08-12 |
Not clear |
| L W Maines, B J Keck, J E Smith, J M Lakosk. Corticosterone regulation of serotonin transporter and 5-HT1A receptor expression in the aging brain. Synapse (New York, N.Y.). vol 32. issue 1. 1999-06-01. PMID:10188639. |
as the serotonergic (5-hydroxytryptamine; 5-ht) system plays a major role in the etiology of depression, a loss of endocrine and neurotransmitter system interactions, including corticosterone regulation of 5-ht transporter (5-htt) and 5-ht receptor expression, may underlie age-related deficits in the regulation of the hypothalamic-pituitary-adrenal (hpa) axis and correlate with an increased incidence of depression with advancing age. |
1999-06-01 |
2023-08-12 |
rat |
| b' B Millet, Y Touitou, M F Poirier, M C Bourdel, E Hantouche, A Bogdan, J P Oli\\xc3\\xa. Plasma melatonin and cortisol in patients with obsessive-compulsive disorder: relationship with axillary temperature, physical activity, and clinical symptoms. Biological psychiatry. vol 44. issue 9. 1999-05-04. PMID:9807642.' |
the investigation of melatonin rhythm may thus provide an indirect clue to neurotransmitter alterations, and allow a biological comparison with depression. |
1999-05-04 |
2023-08-12 |
Not clear |
| M Steciuk, M Kram, G L Kramer, F Pett. Decrease in stress-induced c-Fos-like immunoreactivity in the lateral septal nucleus of learned helpless rats. Brain research. vol 822. issue 1-2. 1999-04-21. PMID:10082906. |
learned helplessness is a phenomenon which has some behavioral and neurotransmitter analogies with human clinical depression. |
1999-04-21 |
2023-08-12 |
human |
| J J Man. The role of in vivo neurotransmitter system imaging studies in understanding major depression. Biological psychiatry. vol 44. issue 11. 1999-03-23. PMID:9836010. |
the role of in vivo neurotransmitter system imaging studies in understanding major depression. |
1999-03-23 |
2023-08-12 |
Not clear |
| M J Moore, P B Moore, P J Sha. Mood disturbances in motor neurone disease. Journal of the neurological sciences. vol 160 Suppl 1. 1999-03-18. PMID:9851650. |
depression is believed to result from underactivity of the serotonergic neurotransmitter system. |
1999-03-18 |
2023-08-12 |
Not clear |
| L Serova, E L Sabban, A Zangen, D H Overstreet, G Yadi. Altered gene expression for catecholamine biosynthetic enzymes and stress response in rat genetic model of depression. Brain research. Molecular brain research. vol 63. issue 1. 1999-01-21. PMID:9838081. |
in this study, we evaluated basal mrna levels of several genes involved in neurotransmitter biosynthesis and the effect of stress in flinder's sensitive line (fsl), a genetic rat model of depression. |
1999-01-21 |
2023-08-12 |
rat |
| R Robitaill. Modulation of synaptic efficacy and synaptic depression by glial cells at the frog neuromuscular junction. Neuron. vol 21. issue 4. 1998-12-04. PMID:9808470. |
hence, the activation by endogenous neurotransmitters of g proteins in pscs induced a profound depression in neurotransmitter release. |
1998-12-04 |
2023-08-12 |
Not clear |
| S Ono, G Baux, M Sekiguchi, P Fossier, N F Morel, I Nihonmatsu, K Hirata, T Awaji, S Takahashi, M Takahash. Regulatory roles of complexins in neurotransmitter release from mature presynaptic nerve terminals. The European journal of neuroscience. vol 10. issue 6. 1998-11-09. PMID:9753100. |
injection of recombinant complexin ii and alphasnap caused depression and facilitation of neurotransmitter release from nerve terminals, respectively. |
1998-11-09 |
2023-08-12 |
rat |
| L Nicholas, K Dawkins, R N Golde. Psychoneuroendocrinology of depression. Prolactin. The Psychiatric clinics of North America. vol 21. issue 2. 1998-10-14. PMID:9670230. |
prolactin provides us with a window to the brain in our quest for understanding the psychobiology of depression, since the regulation of its release involves some of the monamine neurotransmitter systems that have been implicated in the pathophysiology of depression. |
1998-10-14 |
2023-08-12 |
Not clear |
| L Gold, T Back, G Arnold, J Dreier, K M Einhäupl, U Reuter, U Dirnag. Cortical spreading depression-associated hyperemia in rats: involvement of serotonin. Brain research. vol 783. issue 2. 1998-04-13. PMID:9507121. |
we investigated whether the vasoactive neurotransmitter serotonin (5-ht) is involved in cortical spreading depression (csd)-associated hyperemia in the rat. |
1998-04-13 |
2023-08-12 |
rat |
| A Markou, T R Kosten, G F Koo. Neurobiological similarities in depression and drug dependence: a self-medication hypothesis. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology. vol 18. issue 3. 1998-04-02. PMID:9471114. |
finally, the neurotransmitter systems whose function appears to be altered in depression (i.e., serotonin, norepinephrine, acetylcholine, dopamine, gamma-aminobutyric acid, corticotropin releasing factor, neuropeptide y, and somatostatin), as revealed primarily by animal studies, are discussed. |
1998-04-02 |
2023-08-12 |
Not clear |
| A Markou, T R Kosten, G F Koo. Neurobiological similarities in depression and drug dependence: a self-medication hypothesis. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology. vol 18. issue 3. 1998-04-02. PMID:9471114. |
it is concluded that drug dependence and depression may be associated with alterations in some of the same neurotransmitter systems and, in particular, with alterations of neurotransmitter function in limbic-related brain structures. |
1998-04-02 |
2023-08-12 |
Not clear |
| J M Cooney, J V Lucey, V O'Keane, T G Dina. Specificity of the pyridostigmine/growth hormone challenge in the diagnosis of depression. Biological psychiatry. vol 42. issue 9. 1997-12-16. PMID:9347132. |
acetylcholine is a neurotransmitter that has been implicated in the pathophysiology of major depression. |
1997-12-16 |
2023-08-12 |
human |
| R Larisch, A Klimke, H Vosberg, S Löffler, W Gaebel, H W Müller-Gärtne. In vivo evidence for the involvement of dopamine-D2 receptors in striatum and anterior cingulate gyrus in major depression. NeuroImage. vol 5. issue 4 Pt 1. 1997-11-26. PMID:9345554. |
the dopaminergic system is a candidate neurotransmitter system thought to be involved in the pathogenesis of depression. |
1997-11-26 |
2023-08-12 |
Not clear |
| H Markra. A network of tufted layer 5 pyramidal neurons. Cerebral cortex (New York, N.Y. : 1991). vol 7. issue 6. 1997-10-16. PMID:9276177. |
hebbian, anti-hebbian and neuromodulatory-induced modifications of neurotransmitter release probability change the rates of synaptic depression and thereby alter the iteration step size. |
1997-10-16 |
2023-08-12 |
rat |
| S A Montgomer. Is there a role for a pure noradrenergic drug in the treatment of depression? European neuropsychopharmacology : the journal of the European College of Neuropsychopharmacology. vol 7 Suppl 1. 1997-07-31. PMID:9169305. |
the noradrenergic system appears to be associated with increased drive, whereas the serotonergic system relates more to changes in mood and it is possible that the different symptoms of depression may benefit from drugs acting mainly on one or other of the neurotransmitter systems. |
1997-07-31 |
2023-08-12 |
Not clear |
| D M Wilson, A P Ferko, E J Barbieri, G J DiGregorio, E Bobyock, R McMichae. The interaction of dopamine, cocaine, and cocaethylene with ethanol on central nervous system depression in mice. Pharmacology, biochemistry, and behavior. vol 57. issue 1-2. 1997-07-30. PMID:9164556. |
the results of this study showed that the neurotransmitter dopamine and both cocaine and cocaethylene can promote further cns depression in the presence of systemic ethanol, and that dopamine was significantly more potent than cocaine and cocaethylene as measured by the return to the lorr. |
1997-07-30 |
2023-08-12 |
mouse |