| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| R Gutiérre. Synaptic interactions in a newly identified excitatory synapse of Helix aspersa: concurrent enkephalinergic and GABAergic modulation. Brain research. vol 667. issue 2. 1995-05-03. PMID:7697362. |
the values of the smallest detectable epsp after profound depression under normal neurotransmitter release levels corresponded to those obtained under high mg(2+)-low ca2+ conditions (0.33 +/- 0.045 mv) and to the spontaneous epsps (0.4 mv, sigma 2 = 0.02). |
1995-05-03 |
2023-08-12 |
Not clear |
| b' M F Poirier-Littr\\xc3\\xa. [Biological vulnerability to depressive disorders]. L\'Encephale. vol 20 Spec No 4. 1995-04-27. PMID:7895629.' |
the countless laboratory studies carried out in depression have not provided useful etiologic, diagnostic or therapeutic results, and currently, far more attention is given to the interactions between the various neurotransmitter systems than to each system taken individually. |
1995-04-27 |
2023-08-12 |
human |
| A Markou, K Matthews, D H Overstreet, G F Koob, M A Geye. Flinders resistant hypocholinergic rats exhibit startle sensitization and reduced startle thresholds. Biological psychiatry. vol 36. issue 10. 1995-04-13. PMID:7880937. |
based on the hypothesis that depression involves a cholinergic-adrenergic neurotransmitter imbalance, a putative genetic animal model of depression has been developed by selectively breeding rats to exhibit hypocholinergia (flinders resistant line--frl), or hypercholinergia (flinders sensitive line--fsl). |
1995-04-13 |
2023-08-12 |
rat |
| C S Aulakh, J L Hill, D L Murph. Enhanced anorexic responses to m-chlorophenylpiperazine during lithium administration to fawn-hooded rats. Pharmacology, biochemistry, and behavior. vol 49. issue 3. 1995-03-22. PMID:7862734. |
in the present study, we investigated whether functional adaptational changes in the serotonergic neurotransmitter mechanisms regulating food intake following long-term lithium treatment in fawn-hooded rats (a rat strain suggested to represent a genetic model of depression) were different or similar to those previously observed in wistar rats. |
1995-03-22 |
2023-08-12 |
rat |
| C S Aulakh, J L Hill, D L Murph. Enhanced anorexic responses to m-chlorophenylpiperazine during lithium administration to fawn-hooded rats. Pharmacology, biochemistry, and behavior. vol 49. issue 3. 1995-03-22. PMID:7862734. |
this finding contrasts with our previous report demonstrating attenuation of m-cpp-induced anorexia in wistar rats following similar long-term lithium treatment, and therefore suggests a differential adaptation in the serotonergic neurotransmitter mechanisms regulating food intake in a genetic animal model of depression. |
1995-03-22 |
2023-08-12 |
rat |
| M M Katz, J W Maas, A Frazer, S H Koslow, C L Bowden, N Berman, A C Swann, P E Stoke. Drug-induced actions on brain neurotransmitter systems and changes in the behaviors and emotions of depressed patients. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology. vol 11. issue 2. 1995-03-07. PMID:7530963. |
adopting this approach of looking for relationships between changes in components of major depression and changes in neurotransmitter system function, decreases in 5-ht and ne metabolite concentrations in cerebrospinal fluid (csf) in patients treated with tricyclics, were found to be correlated with changes in specific behaviors. |
1995-03-07 |
2023-08-12 |
Not clear |
| A Kamoun, B Delalleau, M Ozu. [Can a serotonin uptake agonist be an authentic antidepressant? Results of a multicenter, multinational therapeutic trial]. L'Encephale. vol 20. issue 5. 1995-02-23. PMID:7828515. |
the classical biochemical hypothesis of depression posits a functional deficit in central neurotransmitter systems particularly serotonin (5-ht) and noradrenaline. |
1995-02-23 |
2023-08-12 |
mouse |
| P Sandor, C M Shapir. Sleep patterns in depression and anxiety: theory and pharmacological effects. Journal of psychosomatic research. vol 38 Suppl 1. 1995-01-24. PMID:7799244. |
the effects on sleep of various neurotransmitter systems implicated in depression and anxiety are outlined. |
1995-01-24 |
2023-08-12 |
Not clear |
| M Wójcik, A Bidziński, M Slósarska, S Puzyńsk. Psychophysiological characteristics and metabolic indices of neurotransmitter metabolism in patients ill with endogenous depression. Psychiatria polska. vol 28. issue 3 Suppl. 1994-10-18. PMID:7916466. |
psychophysiological characteristics and metabolic indices of neurotransmitter metabolism in patients ill with endogenous depression. |
1994-10-18 |
2023-08-12 |
Not clear |
| E K Syvälaht. Biological aspects of depression. Acta psychiatrica Scandinavica. Supplementum. vol 377. 1994-09-06. PMID:7914394. |
it seems clear that susceptibility to depression is linked with deviations in presynaptic and postsynaptic neurotransmitter turnover and function. |
1994-09-06 |
2023-08-12 |
Not clear |
| M Mynlieff, K G Bea. Adenosine acting at an A1 receptor decreases N-type calcium current in mouse motoneurons. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 14. issue 6. 1994-07-11. PMID:8207477. |
among the mechanisms that could contribute to the depression of neurotransmitter release is reduced entry of calcium through channels located in the presynaptic terminal. |
1994-07-11 |
2023-08-12 |
mouse |
| J Svestk. [Antidepressives of the 3rd, 4th and 5th generation]. Ceskoslovenska psychiatrie. vol 90. issue 1. 1994-06-08. PMID:8174184. |
the antidepressant action of preparations of the third generation is mediated only by one of the three main neurotransmitter systems for depression (5-ht, noradrenaline, dopamine) and does not affect muscarine, histamine and adrenergic cerebral systems (e.g. |
1994-06-08 |
2023-08-12 |
Not clear |
| F Pett. Plasma concentrations of gamma-aminobutyric acid (GABA) and mood disorders: a blood test for manic depressive disease? Clinical chemistry. vol 40. issue 2. 1994-03-24. PMID:8313610. |
gamma-aminobutyric acid (gaba), an inhibitory neurotransmitter that serves about one-third of brain neurons, is involved in the development of depression and in the treatment of depression and mania with pharmacological therapy. |
1994-03-24 |
2023-08-12 |
Not clear |
| U Halbreich, L A Lumle. The multiple interactional biological processes that might lead to depression and gender differences in its appearance. Journal of affective disorders. vol 29. issue 2-3. 1994-03-08. PMID:7905489. |
several neurotransmitter systems have been implicated in the pathophysiology of depression. |
1994-03-08 |
2023-08-12 |
Not clear |
| T S Otis, Y De Koninck, I Mod. Characterization of synaptically elicited GABAB responses using patch-clamp recordings in rat hippocampal slices. The Journal of physiology. vol 463. 1993-12-30. PMID:8246190. |
these findings support the hypothesis that the mechanism responsible for paired-pulse depression involves a reduction in neurotransmitter release without postsynaptic alterations in k+ channel activation/inactivation kinetics. |
1993-12-30 |
2023-08-12 |
rat |
| G E Nilsson, P L Lut. Role of GABA in hypoxia tolerance, metabolic depression and hibernation--possible links to neurotransmitter evolution. Comparative biochemistry and physiology. C, Comparative pharmacology and toxicology. vol 105. issue 3. 1993-11-26. PMID:7900957. |
role of gaba in hypoxia tolerance, metabolic depression and hibernation--possible links to neurotransmitter evolution. |
1993-11-26 |
2023-08-12 |
Not clear |
| T A Weh. Seasonal vulnerability to depression. Implications for etiology and treatment. L'Encephale. vol 18 Spec No 4. 1993-10-19. PMID:1308842. |
although no single system has been shown to be responsible for the syndrome, there is evidence that the indole hormone melatonin, the indole neurotransmitter serotonin, and the peptide neurohormone corticotropin releasing hormone (crh) play roles in the pathophysiology and phototherapy of winter depression. |
1993-10-19 |
2023-08-11 |
Not clear |
| P S Katz, M D Kirk, C K Govin. Facilitation and depression at different branches of the same motor axon: evidence for presynaptic differences in release. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 13. issue 7. 1993-08-13. PMID:8331385. |
presynaptic differences in neurotransmitter release contribute strongly to the divergent responses; reduction of the excitatory junction potential amplitude by partial postsynaptic receptor blockade or by desensitization does not change the amount of depression at gm9. |
1993-08-13 |
2023-08-12 |
lobster |
| P S Katz, M D Kirk, C K Govin. Facilitation and depression at different branches of the same motor axon: evidence for presynaptic differences in release. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 13. issue 7. 1993-08-13. PMID:8331385. |
however, reduction of neurotransmitter release with low-ca2+, high-mg2+ saline removes gm9 synaptic depression and reveals that both neuromuscular junctions exhibit frequency-dependent homosynaptic facilitation. |
1993-08-13 |
2023-08-12 |
lobster |
| P S Katz, M D Kirk, C K Govin. Facilitation and depression at different branches of the same motor axon: evidence for presynaptic differences in release. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 13. issue 7. 1993-08-13. PMID:8331385. |
these data suggest that the basis for the differences in transmitter release between the two muscles may be a higher density of release sites in the gm9 synapses that leads to a higher output of neurotransmitter, rapid depletion of transmitter stores, and synaptic depression. |
1993-08-13 |
2023-08-12 |
lobster |