| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Ji-Duo Shen, Yu Wei, Yu-Jie Li, Jing-Yi Qiao, Yu-Cheng L. Curcumin reverses the depressive-like behavior and insulin resistance induced by chronic mild stress. Metabolic brain disease. vol 32. issue 4. 2018-04-23. PMID:28429187. |
insulin resistance has been identified as the key mechanism linking depression and diabetes. |
2018-04-23 |
2023-08-13 |
rat |
| Ji-Duo Shen, Yu Wei, Yu-Jie Li, Jing-Yi Qiao, Yu-Cheng L. Curcumin reverses the depressive-like behavior and insulin resistance induced by chronic mild stress. Metabolic brain disease. vol 32. issue 4. 2018-04-23. PMID:28429187. |
the present study established a rat model of depression complicated by insulin resistance using a 12-week exposure to chronic mild stress (cms) and investigated the therapeutic effects of curcumin. |
2018-04-23 |
2023-08-13 |
rat |
| Prita R Asih, Michelle L Tegg, Hamid Sohrabi, Malcolm Carruthers, Samuel E Gandy, Farid Saad, Giuseppe Verdile, Lars M Ittner, Ralph N Martin. Multiple Mechanisms Linking Type 2 Diabetes and Alzheimer's Disease: Testosterone as a Modifier. Journal of Alzheimer's disease : JAD. vol 59. issue 2. 2018-04-09. PMID:28655134. |
t2dm exhibits many ad pathological features, including reduced brain insulin uptake, lipid dysregulation, inflammation, oxidative stress, and depression; t2dm has also been shown to increase ad risk, and with increasing age, the prevalence of both conditions increases. |
2018-04-09 |
2023-08-13 |
Not clear |
| Erik Lindeman, Lovisa Baer Eriksson, Martin Thorsson, Johanna Nordmark Gras. [High dose insulin euglycemia therapy – an important addition to the treatment arsenal in severe toxic myocardial depression]. Lakartidningen. vol 114. 2018-03-06. PMID:28994852. |
[high dose insulin euglycemia therapy – an important addition to the treatment arsenal in severe toxic myocardial depression]. |
2018-03-06 |
2023-08-13 |
Not clear |
| Erik Lindeman, Lovisa Baer Eriksson, Martin Thorsson, Johanna Nordmark Gras. [High dose insulin euglycemia therapy – an important addition to the treatment arsenal in severe toxic myocardial depression]. Lakartidningen. vol 114. 2018-03-06. PMID:28994852. |
high dose insulin euglycemia therapy - an important addition to the treatment arsenal in severe toxic myocardial depression fifty-nine patients who developed hemodynamic symptoms necessitating treatment with vasopressors or inotropes after poisoning with calcium channel blockers (ccb) and beta blockers (bb) between january 2010 and august 2016 were identified by a search of the poisons information centre database. |
2018-03-06 |
2023-08-13 |
Not clear |
| Tim Pauley, Judith Gargaro, Glen Chenard, Helen Cavanagh, Sandra M McKa. Home-based diabetes self-management coaching delivered by paraprofessionals: A randomized controlled trial. Home health care services quarterly. vol 35. issue 3-4. 2018-01-16. PMID:27897469. |
measures included the diabetes self-efficacy scale (dses), insulin management diabetes self-efficacy scale (imdses), and hospital anxiety and depression scale (hads). |
2018-01-16 |
2023-08-13 |
human |
| Katarzyna Głombik, Joanna Ślusarczyk, Ewa Trojan, Katarzyna Chamera, Bogusława Budziszewska, Władysław Lasoń, Agnieszka Basta-Kai. Regulation of insulin receptor phosphorylation in the brains of prenatally stressed rats: New insight into the benefits of antidepressant drug treatment. European neuropsychopharmacology : the journal of the European College of Neuropsychopharmacology. vol 27. issue 2. 2018-01-15. PMID:28063625. |
a growing body of evidence supports the involvement of disturbances in the brain insulin pathway in the pathogenesis of depression. |
2018-01-15 |
2023-08-13 |
rat |
| M'Balu Webb, Melanie Davies, Nuzhat Ashra, Danielle Bodicoat, Emer Brady, David Webb, Calum Moulton, Khalida Ismail, Kamlesh Khunt. The association between depressive symptoms and insulin resistance, inflammation and adiposity in men and women. PloS one. vol 12. issue 11. 2017-12-26. PMID:29190710. |
depression has been shown to be associated with elevated leptin levels, low-grade inflammation and insulin resistance. |
2017-12-26 |
2023-08-13 |
Not clear |
| Lisa S Olive, Rohan M Telford, D G Byrne, Walter P Abhayaratna, Richard D Telfor. Symptoms of stress and depression effect percentage of body fat and insulin resistance in healthy youth: LOOK longitudinal study. Health psychology : official journal of the Division of Health Psychology, American Psychological Association. vol 36. issue 8. 2017-12-25. PMID:28541073. |
symptoms of stress and depression effect percentage of body fat and insulin resistance in healthy youth: look longitudinal study. |
2017-12-25 |
2023-08-13 |
Not clear |
| Lauren B Shomaker, Nichole R Kelly, Courtney K Pickworth, Omni L Cassidy, Rachel M Radin, Lisa M Shank, Anna Vannucci, Katherine A Thompson, Sara A Armaiz-Flores, Sheila M Brady, Andrew P Demidowich, Ovidiu A Galescu, Amber B Courville, Cara Olsen, Kong Y Chen, Eric Stice, Marian Tanofsky-Kraff, Jack A Yanovsk. A Randomized Controlled Trial to Prevent Depression and Ameliorate Insulin Resistance in Adolescent Girls at Risk for Type 2 Diabetes. Annals of behavioral medicine : a publication of the Society of Behavioral Medicine. vol 50. issue 5. 2017-12-21. PMID:27333897. |
a randomized controlled trial to prevent depression and ameliorate insulin resistance in adolescent girls at risk for type 2 diabetes. |
2017-12-21 |
2023-08-13 |
Not clear |
| Benedetta Bigio, Aleksander A Mathé, Vasco C Sousa, Danielle Zelli, Per Svenningsson, Bruce S McEwen, Carla Nasc. Epigenetics and energetics in ventral hippocampus mediate rapid antidepressant action: Implications for treatment resistance. Proceedings of the National Academy of Sciences of the United States of America. vol 113. issue 28. 2017-11-27. PMID:27354525. |
agents such as lac that regulate metabolic factors and reduce glutamate overflow could rapidly ameliorate depression and could also be considered for treatment of insulin resistance in depressed subjects. |
2017-11-27 |
2023-08-13 |
human |
| Sayonara Rangel Oliveira, Ana Paula Kallaur, Josiane Lopes, Andrea Name Colado Simão, Edna Maria Reiche, Elaine Regina Delicato de Almeida, Helena Kaminami Morimoto, Wildea Lice de Carvalho Jennings de Pereira, Daniela Frizon Alfieri, Tamires Flauzino, Caio de Meleck Proença, Anna Maria Gomes, Damacio Ramón Kaimen-Maciel, Michael Mae. Insulin resistance, atherogenicity, and iron metabolism in multiple sclerosis with and without depression: Associations with inflammatory and oxidative stress biomarkers and uric acid. Psychiatry research. vol 250. 2017-11-16. PMID:28152396. |
insulin resistance, atherogenicity, and iron metabolism in multiple sclerosis with and without depression: associations with inflammatory and oxidative stress biomarkers and uric acid. |
2017-11-16 |
2023-08-13 |
Not clear |
| Sayonara Rangel Oliveira, Ana Paula Kallaur, Josiane Lopes, Andrea Name Colado Simão, Edna Maria Reiche, Elaine Regina Delicato de Almeida, Helena Kaminami Morimoto, Wildea Lice de Carvalho Jennings de Pereira, Daniela Frizon Alfieri, Tamires Flauzino, Caio de Meleck Proença, Anna Maria Gomes, Damacio Ramón Kaimen-Maciel, Michael Mae. Insulin resistance, atherogenicity, and iron metabolism in multiple sclerosis with and without depression: Associations with inflammatory and oxidative stress biomarkers and uric acid. Psychiatry research. vol 250. 2017-11-16. PMID:28152396. |
depression is accompanied by metabolic disorders in iron metabolism, lipoproteins, and insulin resistance. |
2017-11-16 |
2023-08-13 |
Not clear |
| Sayonara Rangel Oliveira, Ana Paula Kallaur, Josiane Lopes, Andrea Name Colado Simão, Edna Maria Reiche, Elaine Regina Delicato de Almeida, Helena Kaminami Morimoto, Wildea Lice de Carvalho Jennings de Pereira, Daniela Frizon Alfieri, Tamires Flauzino, Caio de Meleck Proença, Anna Maria Gomes, Damacio Ramón Kaimen-Maciel, Michael Mae. Insulin resistance, atherogenicity, and iron metabolism in multiple sclerosis with and without depression: Associations with inflammatory and oxidative stress biomarkers and uric acid. Psychiatry research. vol 250. 2017-11-16. PMID:28152396. |
we measured plasma levels of ferritin, iron, lipids, insulin, and glucose and computed the homeostasis model assessment (homa2ir) and atherogenic index of plasma (aip) in ms patients with and without depression and healthy controls. |
2017-11-16 |
2023-08-13 |
Not clear |
| Sayonara Rangel Oliveira, Ana Paula Kallaur, Josiane Lopes, Andrea Name Colado Simão, Edna Maria Reiche, Elaine Regina Delicato de Almeida, Helena Kaminami Morimoto, Wildea Lice de Carvalho Jennings de Pereira, Daniela Frizon Alfieri, Tamires Flauzino, Caio de Meleck Proença, Anna Maria Gomes, Damacio Ramón Kaimen-Maciel, Michael Mae. Insulin resistance, atherogenicity, and iron metabolism in multiple sclerosis with and without depression: Associations with inflammatory and oxidative stress biomarkers and uric acid. Psychiatry research. vol 250. 2017-11-16. PMID:28152396. |
homa2ir and insulin were predicted by diagnosis (increased in ms), age and body mass index (bmi); aip by diagnosis, sex, bmi, crp, and uric acid; triglycerides by diagnosis (higher in ms without depression), age, bmi and uric acid; ferritin by diagnosis (higher in ms), sex, crp, and albumin; and iron by albumin. |
2017-11-16 |
2023-08-13 |
Not clear |
| Sayonara Rangel Oliveira, Ana Paula Kallaur, Josiane Lopes, Andrea Name Colado Simão, Edna Maria Reiche, Elaine Regina Delicato de Almeida, Helena Kaminami Morimoto, Wildea Lice de Carvalho Jennings de Pereira, Daniela Frizon Alfieri, Tamires Flauzino, Caio de Meleck Proença, Anna Maria Gomes, Damacio Ramón Kaimen-Maciel, Michael Mae. Insulin resistance, atherogenicity, and iron metabolism in multiple sclerosis with and without depression: Associations with inflammatory and oxidative stress biomarkers and uric acid. Psychiatry research. vol 250. 2017-11-16. PMID:28152396. |
depression in ms is not associated with increased insulin resistance and atherogenicity but with lowered iron. |
2017-11-16 |
2023-08-13 |
Not clear |
| Jae-Hon Lee, Sung Keun Park, Jae-Hong Ryoo, Chang-Mo Oh, Rodrigo B Mansur, Jeffrey E Alfonsi, Danielle S Cha, Yena Lee, Roger S McIntyre, Ju Young Jun. The association between insulin resistance and depression in the Korean general population. Journal of affective disorders. vol 208. 2017-10-30. PMID:27810270. |
the association between insulin resistance and depression in the korean general population. |
2017-10-30 |
2023-08-13 |
Not clear |
| Jae-Hon Lee, Sung Keun Park, Jae-Hong Ryoo, Chang-Mo Oh, Rodrigo B Mansur, Jeffrey E Alfonsi, Danielle S Cha, Yena Lee, Roger S McIntyre, Ju Young Jun. The association between insulin resistance and depression in the Korean general population. Journal of affective disorders. vol 208. 2017-10-30. PMID:27810270. |
previous studies showed that the insulin resistance (ir) could be related to depression. |
2017-10-30 |
2023-08-13 |
Not clear |
| Su-Min Lim, Soo-Hyun Park, Naveen Sharma, Sung-Su Kim, Jae-Ryeong Lee, Jun-Sub Jung, Hong-Won Su. Blood glucose regulation mechanism in depressive disorder animal model during hyperglycemic states. Brain research bulletin. vol 124. 2017-10-26. PMID:27034116. |
the up-regulated insulin level induced by d-glucose feeding or restraint stress was reduced in the depression group. |
2017-10-26 |
2023-08-13 |
mouse |
| Su-Min Lim, Soo-Hyun Park, Naveen Sharma, Sung-Su Kim, Jae-Ryeong Lee, Jun-Sub Jung, Hong-Won Su. Blood glucose regulation mechanism in depressive disorder animal model during hyperglycemic states. Brain research bulletin. vol 124. 2017-10-26. PMID:27034116. |
whereas the insulin level in depression group was not altered when mice were administered clonidine i.t. |
2017-10-26 |
2023-08-13 |
mouse |