| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Weikang Cai, Chang Xue, Masaji Sakaguchi, Masahiro Konishi, Alireza Shirazian, Heather A Ferris, Mengyao E Li, Ruichao Yu, Andre Kleinridders, Emmanuel N Pothos, C Ronald Kah. Insulin regulates astrocyte gliotransmission and modulates behavior. The Journal of clinical investigation. vol 128. issue 7. 2019-09-16. PMID:29664737. |
thus, astrocytic insulin signaling plays an important role in dopaminergic signaling, providing a potential mechanism by which astrocytic insulin action may contribute to increased rates of depression in people with diabetes, obesity, and other insulin-resistant states. |
2019-09-16 |
2023-08-13 |
mouse |
| A B Kamrul-Hasan, M Palash-Molla, M Mainul-Ahsan, A J Gaffar, M Asaduzzaman, M Saifuddin, M S Rahman, F Akter, H Rahman, S K Talukder, M Islam, P K Chanda, N I Siddiqui, S Seli. Prevalence and Predictors of Depression among Patients with Type 2 Diabetes: A Multicenter Cross-sectional Study from Bangladesh. Mymensingh medical journal : MMJ. vol 28. issue 1. 2019-07-16. PMID:30755546. |
in t2dm subjects, diabetes in the family members, the presence of other comorbidities, diabetic complications, diabetes duration >5 years, insulin use, using insulin syringe for injection, albuminuria and ckd were the important predictors of depression. |
2019-07-16 |
2023-08-13 |
human |
| Igor Pomytkin, João P Costa-Nunes, Vladimir Kasatkin, Ekaterina Veniaminova, Anna Demchenko, Alexey Lyundup, Klaus-Peter Lesch, Eugene D Ponomarev, Tatyana Strekalov. Insulin receptor in the brain: Mechanisms of activation and the role in the CNS pathology and treatment. CNS neuroscience & therapeutics. vol 24. issue 9. 2019-07-15. PMID:29691988. |
deficiencies in ir activation, insulin availability, and downstream ir-related mechanisms may result in aberrant ir-mediated functions and, subsequently, a broad range of brain disorders, including neurodevelopmental syndromes, neoplasms, neurodegenerative conditions, and depression. |
2019-07-15 |
2023-08-13 |
Not clear |
| Jan Detka, Joanna Ślusarczyk, Anna Kurek, Mateusz Kucharczyk, Tomasz Adamus, Paweł Konieczny, Marta Kubera, Agnieszka Basta-Kaim, Władysław Lasoń, Bogusława Budziszewsk. Hypothalamic insulin and glucagon-like peptide-1 levels in an animal model of depression and their effect on corticotropin-releasing hormone promoter gene activity in a hypothalamic cell line. Pharmacological reports : PR. vol 71. issue 2. 2019-06-17. PMID:30831439. |
hypothalamic insulin and glucagon-like peptide-1 levels in an animal model of depression and their effect on corticotropin-releasing hormone promoter gene activity in a hypothalamic cell line. |
2019-06-17 |
2023-08-13 |
Not clear |
| Joe Alexander, Roger A Edwards, Marina Brodsky, Luigi Manca, Roberto Grugni, Alberto Savoldelli, Gianluca Bonfanti, Birol Emir, Ed Whalen, Steve Watt, Bruce Parson. Using time series analysis approaches for improved prediction of pain outcomes in subgroups of patients with painful diabetic peripheral neuropathy. PloS one. vol 13. issue 12. 2019-05-08. PMID:30521533. |
six clusters were identified according to baseline variables (gender, age, insulin use, body mass index, depression history, pregabalin monotherapy, prior gabapentin, pain score, and pain-related sleep interference score). |
2019-05-08 |
2023-08-13 |
Not clear |
| Dareen A Youssef, Hassan M El-Fayoumi, Mona F Mahmou. Beta-caryophyllene alleviates diet-induced neurobehavioral changes in rats: The role of CB2 and PPAR-γ receptors. Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie. vol 110. 2019-04-18. PMID:30469079. |
this study was designed to examine the role of bcp in improving diet-induced metabolic (insulin resistance), neurobehavioral (anxiety, depression and memory deficit), and neurochemical (oxidative, inflammatory and neurotrophic factor) alterations in the prefrontal cortex of obese rats' brain. |
2019-04-18 |
2023-08-13 |
rat |
| S Roat-Shumway, T E Wroolie, K Watson, A F Schatzberg, N L Rasgo. Cognitive effects of mifepristone in overweight, euthymic adults with depressive disorders. Journal of affective disorders. vol 239. 2019-03-14. PMID:30025313. |
insulin resistance is posited to contribute to the cognitive deficits observed in individuals who have depression. |
2019-03-14 |
2023-08-13 |
Not clear |
| Tetsushi Hamaguchi, Yushi Hirota, Takehito Takeuchi, Yasushi Nakagawa, Atsuko Matsuoka, Masaaki Matsumoto, Hiroyuki Awano, Kazumoto Iijima, Pei Chieng Cha, Wataru Satake, Tatsushi Toda, Wataru Ogaw. Treatment of a case of severe insulin resistance as a result of a PIK3R1 mutation with a sodium-glucose cotransporter 2 inhibitor. Journal of diabetes investigation. vol 9. issue 5. 2019-03-12. PMID:29476696. |
a japanese woman aged in her late 30s with severe insulin resistance and bodily features including a triangular face, prominent forehead, small chin, large and low-set ears, and ocular depression was investigated. |
2019-03-12 |
2023-08-13 |
Not clear |
| Felix Day, Tugce Karaderi, Michelle R Jones, Cindy Meun, Chunyan He, Alex Drong, Peter Kraft, Nan Lin, Hongyan Huang, Linda Broer, Reedik Magi, Richa Saxena, Triin Laisk, Margrit Urbanek, M Geoffrey Hayes, Gudmar Thorleifsson, Juan Fernandez-Tajes, Anubha Mahajan, Benjamin H Mullin, Bronwyn G A Stuckey, Timothy D Spector, Scott G Wilson, Mark O Goodarzi, Lea Davis, Barbara Obermayer-Pietsch, André G Uitterlinden, Verneri Anttila, Benjamin M Neale, Marjo-Riitta Jarvelin, Bart Fauser, Irina Kowalska, Jenny A Visser, Marianne Andersen, Ken Ong, Elisabet Stener-Victorin, David Ehrmann, Richard S Legro, Andres Salumets, Mark I McCarthy, Laure Morin-Papunen, Unnur Thorsteinsdottir, Kari Stefansson, Unnur Styrkarsdottir, John R B Perry, Andrea Dunaif, Joop Laven, Steve Franks, Cecilia M Lindgren, Corrine K Wel. Large-scale genome-wide meta-analysis of polycystic ovary syndrome suggests shared genetic architecture for different diagnosis criteria. PLoS genetics. vol 14. issue 12. 2019-03-04. PMID:30566500. |
mendelian randomization analyses suggested variants associated with body mass index, fasting insulin, menopause timing, depression and male-pattern balding play a causal role in pcos. |
2019-03-04 |
2023-08-13 |
human |
| Eleni A Greenwood, Lauri A Pasch, Marcelle I Cedars, Richard S Legro, Esther Eisenberg, Heather G Huddlesto. Insulin resistance is associated with depression risk in polycystic ovary syndrome. Fertility and sterility. vol 110. issue 1. 2019-01-28. PMID:29908775. |
insulin resistance is associated with depression risk in polycystic ovary syndrome. |
2019-01-28 |
2023-08-13 |
Not clear |
| Eleni A Greenwood, Lauri A Pasch, Marcelle I Cedars, Richard S Legro, Esther Eisenberg, Heather G Huddlesto. Insulin resistance is associated with depression risk in polycystic ovary syndrome. Fertility and sterility. vol 110. issue 1. 2019-01-28. PMID:29908775. |
to test the hypothesis that insulin resistance is associated with depression risk in polycystic ovary syndrome (pcos). |
2019-01-28 |
2023-08-13 |
Not clear |
| Han-Cheng Qiu, Hui-Zhen Liu, Xuemei Li, Xianwei Zeng, Ji-Zong Zha. Insulin resistance as estimated by homeostasis model assessment predicts incident post-stroke depression in Chinese subjects from ischemic stroke. Journal of affective disorders. vol 231. 2018-08-29. PMID:29408157. |
insulin resistance as estimated by homeostasis model assessment predicts incident post-stroke depression in chinese subjects from ischemic stroke. |
2018-08-29 |
2023-08-13 |
human |
| Han-Cheng Qiu, Hui-Zhen Liu, Xuemei Li, Xianwei Zeng, Ji-Zong Zha. Insulin resistance as estimated by homeostasis model assessment predicts incident post-stroke depression in Chinese subjects from ischemic stroke. Journal of affective disorders. vol 231. 2018-08-29. PMID:29408157. |
previous studies suggested that insulin resistance (ir) may be a significant causal risk factor for cardiovascular events and depression independent of other risk factors. |
2018-08-29 |
2023-08-13 |
human |
| Han-Cheng Qiu, Hui-Zhen Liu, Xuemei Li, Xianwei Zeng, Ji-Zong Zha. Insulin resistance as estimated by homeostasis model assessment predicts incident post-stroke depression in Chinese subjects from ischemic stroke. Journal of affective disorders. vol 231. 2018-08-29. PMID:29408157. |
in this prospective, we assess the value of homeostatic model assessment of insulin resistance (homa-ir) at admission to predict post-stroke depression (psd) later developed at 3 months follow-up. |
2018-08-29 |
2023-08-13 |
human |
| Lauren B Shomaker, Nichole R Kelly, Rachel M Radin, Omni L Cassidy, Lisa M Shank, Sheila M Brady, Andrew P Demidowich, Cara H Olsen, Kong Y Chen, Eric Stice, Marian Tanofsky-Kraff, Jack A Yanovsk. Prevention of insulin resistance in adolescents at risk for type 2 diabetes with depressive symptoms: 1-year follow-up of a randomized trial. Depression and anxiety. vol 34. issue 10. 2018-05-14. PMID:28370947. |
depression is associated with poor insulin sensitivity. |
2018-05-14 |
2023-08-13 |
Not clear |
| Lauren B Shomaker, Nichole R Kelly, Rachel M Radin, Omni L Cassidy, Lisa M Shank, Sheila M Brady, Andrew P Demidowich, Cara H Olsen, Kong Y Chen, Eric Stice, Marian Tanofsky-Kraff, Jack A Yanovsk. Prevention of insulin resistance in adolescents at risk for type 2 diabetes with depressive symptoms: 1-year follow-up of a randomized trial. Depression and anxiety. vol 34. issue 10. 2018-05-14. PMID:28370947. |
we evaluated the long-term effects of a cognitive behavioral therapy (cbt) program for prevention of depression on insulin sensitivity in adolescents at risk for type 2 diabetes (t2d) with depressive symptoms. |
2018-05-14 |
2023-08-13 |
Not clear |
| Osman Özdemir, Zehra Kurdoglu, Saliha Yıldız, Pınar Güzel Özdemir, Ekrem Yilma. The relationship between atypical depression and insülin resistance in patients with polycystic ovary syndrome and major depression. Psychiatry research. vol 258. 2018-05-10. PMID:28168992. |
in this study, we aimed to examine the relationship between atypical depression and insulin resistance (ir) in patients with polycystic ovary syndrome (pcos) and major depression. |
2018-05-10 |
2023-08-13 |
human |
| Osman Özdemir, Zehra Kurdoglu, Saliha Yıldız, Pınar Güzel Özdemir, Ekrem Yilma. The relationship between atypical depression and insülin resistance in patients with polycystic ovary syndrome and major depression. Psychiatry research. vol 258. 2018-05-10. PMID:28168992. |
insulin resistance was higher in the pcos patients than in the control subjects and the depression patients. |
2018-05-10 |
2023-08-13 |
human |
| Genevieve Maliszewski, Susana R Patton, L Kurt Midyett, Mark A Clement. The Interactive Effect of Diabetes Family Conflict and Depression on Insulin Bolusing Behaviors for Youth. Journal of diabetes science and technology. vol 11. issue 3. 2018-04-26. PMID:27543271. |
the interactive effect of diabetes family conflict and depression on insulin bolusing behaviors for youth. |
2018-04-26 |
2023-08-13 |
Not clear |
| Genevieve Maliszewski, Susana R Patton, L Kurt Midyett, Mark A Clement. The Interactive Effect of Diabetes Family Conflict and Depression on Insulin Bolusing Behaviors for Youth. Journal of diabetes science and technology. vol 11. issue 3. 2018-04-26. PMID:27543271. |
the current study assessed the unique and interactive roles diabetes family conflict and depression have on insulin bolusing behaviors for youth ages 10-16 years. |
2018-04-26 |
2023-08-13 |
Not clear |