| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Fan Wang, Shunying Yu, Rubai Zhou, Ruizhi Mao, Guoqing Zhao, Xiaoyun Guo, Qingqing Xu, Jun Chen, Chen Zhang, Yiru Fan. Variants in the Upstream Region of the Insulin Receptor Substrate-1 Gene Is Associated with Major Depressive Disorder in the Han Chinese Population. Neuropsychiatric disease and treatment. vol 16. 2020-09-28. PMID:32110024. |
insulin receptor substrate-1 (irs-1) is one of the critical downstream molecules in the insulin resistance signaling pathway, linking depression and diabetes. |
2020-09-28 |
2023-08-13 |
Not clear |
| Geoffrey Hacket. Should All Men with Type 2 Diabetes Be Routinely Prescribed a Phosphodiesterase Type 5 Inhibitor? The world journal of men's health. vol 38. issue 3. 2020-09-28. PMID:32378365. |
important health problems in men such as type 2 diabetes (t2dm), insulin resistance, erectile dysfunction, benign prostatic hyperplasia and depression have been shown to have to share common pathological processes, such as endothelial dysfunction and inflammation. |
2020-09-28 |
2023-08-13 |
Not clear |
| Andrea D Mekonnen, Aubrey A Mills, Andrea L Wilhite, Theresa K Hoffma. Desvenlafaxine-associated hyperglycemia: A case report and literature review. The mental health clinician. vol 10. issue 3. 2020-09-28. PMID:32420005. |
over the course of 3 months after desvenlafaxine initiation, insulin glargine was increased and insulin lispro was initiated as the patient refused alternative antidepressant therapy due to favorable improvements in anxiety and depression. |
2020-09-28 |
2023-08-13 |
Not clear |
| Xiaojuan Li, Wenqi Qiu, Nan Li, Xiaoli Da, Qingyu Ma, Yajing Hou, Tingye Wang, Ming Song, Jiaxu Che. Susceptibility to Hyperglycemia in Rats With Stress-Induced Depressive-Like Behavior: Involvement of IL-6 Mediated Glucose Homeostasis Signaling. Frontiers in psychiatry. vol 11. 2020-09-28. PMID:32655424. |
cytokine-mediated inflammation in brain may play important roles in the pathogenesis of depression and insulin resistance. |
2020-09-28 |
2023-08-13 |
rat |
| Young-Kook Kim, Oh Yoen Kim, Juhyun Son. Alleviation of Depression by Glucagon-Like Peptide 1 Through the Regulation of Neuroinflammation, Neurotransmitters, Neurogenesis, and Synaptic Function. Frontiers in pharmacology. vol 11. 2020-09-28. PMID:32922295. |
the onset and recurrence of depression have been linked to diverse metabolic factors, including hyperglycemia, dyslipidemia, and insulin resistance. |
2020-09-28 |
2023-08-13 |
Not clear |
| Qais S Dirar, Hebah M Musalem, Selwa A F Al-Hazzaa, Abdulaziz A Al Zoba, Amal A Almalk. Effect of Pegylated Interferon and Mitomycin C on Ocular Surface Squamous Neoplasia in Xeroderma Pigmentosum: A Case Series. The American journal of case reports. vol 21. 2020-09-24. PMID:32251268. |
transient mental depression was reported in 2 of our patients, and only 1 patient developed autoimmune diabetes mellitus, which required insulin therapy after the discontinuation of the peg-ifn-alpha-2b. |
2020-09-24 |
2023-08-13 |
Not clear |
| Senthil Kumaran Satyanarayanan, Yin-Hwa Shih, Yeong-Ray Wen, Mahalakshmi Palani, Yi-Wen Lin, Huanxing Su, Piotr Gałecki, Kuan-Pin S. miR-200a-3p modulates gene expression in comorbid pain and depression: Molecular implication for central sensitization. Brain, behavior, and immunity. vol 82. 2020-09-16. PMID:31479730. |
only the mir-200a-3p level was continuously elevated under prolonged stress, suggesting roles of reduced neurogenesis, inflammatory activation, disturbed circadian rhythm, lipid metabolism, and insulin secretion in the co-existence of pain and depression. |
2020-09-16 |
2023-08-13 |
rat |
| Hayato Akimoto, Kotoe Tezuka, Yayoi Nishida, Tomohiro Nakayama, Yasuo Takahashi, Satoshi Asa. Association between use of oral hypoglycemic agents in Japanese patients with type 2 diabetes mellitus and risk of depression: A retrospective cohort study. Pharmacology research & perspectives. vol 7. issue 6. 2020-07-06. PMID:31768258. |
since brain insulin resistance plays a potential role in depression, the future risk of depression in patients with t2dm may be altered depending on the class of oral hypoglycemic agent (oha) used for t2dm therapy. |
2020-07-06 |
2023-08-13 |
Not clear |
| Janice K Kiecolt-Glaser, Stephanie J Wilson, Annelise Madiso. Marriage and Gut (Microbiome) Feelings: Tracing Novel Dyadic Pathways to Accelerated Aging. Psychosomatic medicine. vol 81. issue 8. 2020-07-02. PMID:30308579. |
chronic marital stress and depression can elevate the risk for obesity, metabolic syndrome, and cardiovascular disease by altering resting energy expenditure, insulin production, and triglyceride responses after unhealthy meals. |
2020-07-02 |
2023-08-13 |
Not clear |
| Juliane Zemdegs, Hugo Martin, Hiranya Pintana, Sebastien Bullich, Stella Manta, Marie A Marqués, Cédric Moro, Sophie Layé, Fabien Ducrocq, Nipon Chattipakorn, Siriporn C Chattipakorn, Claire Rampon, Luc Pénicaud, Xavier Fioramonti, Bruno P Guiar. Metformin Promotes Anxiolytic and Antidepressant-Like Responses in Insulin-Resistant Mice by Decreasing Circulating Branched-Chain Amino Acids. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 39. issue 30. 2020-06-17. PMID:31160539. |
epidemiological studies indicate that insulin resistance (ir), a hallmark of type 2 diabetes, is associated with an increased risk of major depression. |
2020-06-17 |
2023-08-13 |
mouse |
| Xiao Han Zou, Li Hua Sun, Wei Yang, Bing Jin Li, Ran Ji Cu. Potential role of insulin on the pathogenesis of depression. Cell proliferation. vol 53. issue 5. 2020-06-15. PMID:32281722. |
potential role of insulin on the pathogenesis of depression. |
2020-06-15 |
2023-08-13 |
Not clear |
| Xiao Han Zou, Li Hua Sun, Wei Yang, Bing Jin Li, Ran Ji Cu. Potential role of insulin on the pathogenesis of depression. Cell proliferation. vol 53. issue 5. 2020-06-15. PMID:32281722. |
the regulation of insulin on depression and depression-like behaviour has been widely reported. |
2020-06-15 |
2023-08-13 |
Not clear |
| Xiao Han Zou, Li Hua Sun, Wei Yang, Bing Jin Li, Ran Ji Cu. Potential role of insulin on the pathogenesis of depression. Cell proliferation. vol 53. issue 5. 2020-06-15. PMID:32281722. |
insulin and activation of its receptor can promote learning and memory, affect the hypothalamic-pituitary-adrenal axis (hpa) balance, regulate the secretion of neurotrophic factors and neurotransmitters, interact with gastrointestinal microbiome, exert neuroprotective effects and have an impact on depression. |
2020-06-15 |
2023-08-13 |
Not clear |
| Xiao Han Zou, Li Hua Sun, Wei Yang, Bing Jin Li, Ran Ji Cu. Potential role of insulin on the pathogenesis of depression. Cell proliferation. vol 53. issue 5. 2020-06-15. PMID:32281722. |
however, the role of insulin on depression remains largely unclear. |
2020-06-15 |
2023-08-13 |
Not clear |
| Xiao Han Zou, Li Hua Sun, Wei Yang, Bing Jin Li, Ran Ji Cu. Potential role of insulin on the pathogenesis of depression. Cell proliferation. vol 53. issue 5. 2020-06-15. PMID:32281722. |
therefore, in this review, we summarized the potential role of insulin on depression. |
2020-06-15 |
2023-08-13 |
Not clear |
| Xiao Han Zou, Li Hua Sun, Wei Yang, Bing Jin Li, Ran Ji Cu. Potential role of insulin on the pathogenesis of depression. Cell proliferation. vol 53. issue 5. 2020-06-15. PMID:32281722. |
it may provide new insight for clarifying role of insulin on the pathogenesis of depression. |
2020-06-15 |
2023-08-13 |
Not clear |
| Lauren D Gulley, Lauren B Shomaker, Nichole R Kelly, Kong Y Chen, Eric Stice, Cara H Olsen, Marian Tanofsky-Kraff, Jack A Yanovsk. Indirect Effects of a Cognitive-Behavioral Intervention on Adolescent Weight and Insulin Resistance Through Decreasing Depression in a Randomized Controlled Trial. Journal of pediatric psychology. vol 44. issue 10. 2020-05-06. PMID:31393981. |
indirect effects of a cognitive-behavioral intervention on adolescent weight and insulin resistance through decreasing depression in a randomized controlled trial. |
2020-05-06 |
2023-08-13 |
Not clear |
| Lauren D Gulley, Lauren B Shomaker, Nichole R Kelly, Kong Y Chen, Eric Stice, Cara H Olsen, Marian Tanofsky-Kraff, Jack A Yanovsk. Indirect Effects of a Cognitive-Behavioral Intervention on Adolescent Weight and Insulin Resistance Through Decreasing Depression in a Randomized Controlled Trial. Journal of pediatric psychology. vol 44. issue 10. 2020-05-06. PMID:31393981. |
depression is linked to excess weight, insulin resistance, and type 2 diabetes (t2d). |
2020-05-06 |
2023-08-13 |
Not clear |
| Lauren D Gulley, Lauren B Shomaker, Nichole R Kelly, Kong Y Chen, Eric Stice, Cara H Olsen, Marian Tanofsky-Kraff, Jack A Yanovsk. Indirect Effects of a Cognitive-Behavioral Intervention on Adolescent Weight and Insulin Resistance Through Decreasing Depression in a Randomized Controlled Trial. Journal of pediatric psychology. vol 44. issue 10. 2020-05-06. PMID:31393981. |
we previously reported that in adolescent girls at-risk for t2d with moderately elevated depression, randomization to cognitive-behavioral therapy (cbt) produced greater decreases in depression at post-treament and greater decreases in fasting/2-h insulin at 1 year, compared to health education (he). |
2020-05-06 |
2023-08-13 |
Not clear |
| Lauren D Gulley, Lauren B Shomaker, Nichole R Kelly, Kong Y Chen, Eric Stice, Cara H Olsen, Marian Tanofsky-Kraff, Jack A Yanovsk. Indirect Effects of a Cognitive-Behavioral Intervention on Adolescent Weight and Insulin Resistance Through Decreasing Depression in a Randomized Controlled Trial. Journal of pediatric psychology. vol 44. issue 10. 2020-05-06. PMID:31393981. |
we examined whether decreasing depression explained intervention effects on body composition and insulin outcomes. |
2020-05-06 |
2023-08-13 |
Not clear |