| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Xiao Han Zou, Li Hua Sun, Wei Yang, Bing Jin Li, Ran Ji Cu. Potential role of insulin on the pathogenesis of depression. Cell proliferation. vol 53. issue 5. 2020-06-15. PMID:32281722. |
potential role of insulin on the pathogenesis of depression. |
2020-06-15 |
2023-08-13 |
Not clear |
| Xiao Han Zou, Li Hua Sun, Wei Yang, Bing Jin Li, Ran Ji Cu. Potential role of insulin on the pathogenesis of depression. Cell proliferation. vol 53. issue 5. 2020-06-15. PMID:32281722. |
the regulation of insulin on depression and depression-like behaviour has been widely reported. |
2020-06-15 |
2023-08-13 |
Not clear |
| Xiao Han Zou, Li Hua Sun, Wei Yang, Bing Jin Li, Ran Ji Cu. Potential role of insulin on the pathogenesis of depression. Cell proliferation. vol 53. issue 5. 2020-06-15. PMID:32281722. |
insulin and activation of its receptor can promote learning and memory, affect the hypothalamic-pituitary-adrenal axis (hpa) balance, regulate the secretion of neurotrophic factors and neurotransmitters, interact with gastrointestinal microbiome, exert neuroprotective effects and have an impact on depression. |
2020-06-15 |
2023-08-13 |
Not clear |
| Xiao Han Zou, Li Hua Sun, Wei Yang, Bing Jin Li, Ran Ji Cu. Potential role of insulin on the pathogenesis of depression. Cell proliferation. vol 53. issue 5. 2020-06-15. PMID:32281722. |
however, the role of insulin on depression remains largely unclear. |
2020-06-15 |
2023-08-13 |
Not clear |
| Xiao Han Zou, Li Hua Sun, Wei Yang, Bing Jin Li, Ran Ji Cu. Potential role of insulin on the pathogenesis of depression. Cell proliferation. vol 53. issue 5. 2020-06-15. PMID:32281722. |
therefore, in this review, we summarized the potential role of insulin on depression. |
2020-06-15 |
2023-08-13 |
Not clear |
| Xiao Han Zou, Li Hua Sun, Wei Yang, Bing Jin Li, Ran Ji Cu. Potential role of insulin on the pathogenesis of depression. Cell proliferation. vol 53. issue 5. 2020-06-15. PMID:32281722. |
it may provide new insight for clarifying role of insulin on the pathogenesis of depression. |
2020-06-15 |
2023-08-13 |
Not clear |
| Lauren D Gulley, Lauren B Shomaker, Nichole R Kelly, Kong Y Chen, Eric Stice, Cara H Olsen, Marian Tanofsky-Kraff, Jack A Yanovsk. Indirect Effects of a Cognitive-Behavioral Intervention on Adolescent Weight and Insulin Resistance Through Decreasing Depression in a Randomized Controlled Trial. Journal of pediatric psychology. vol 44. issue 10. 2020-05-06. PMID:31393981. |
indirect effects of a cognitive-behavioral intervention on adolescent weight and insulin resistance through decreasing depression in a randomized controlled trial. |
2020-05-06 |
2023-08-13 |
Not clear |
| Lauren D Gulley, Lauren B Shomaker, Nichole R Kelly, Kong Y Chen, Eric Stice, Cara H Olsen, Marian Tanofsky-Kraff, Jack A Yanovsk. Indirect Effects of a Cognitive-Behavioral Intervention on Adolescent Weight and Insulin Resistance Through Decreasing Depression in a Randomized Controlled Trial. Journal of pediatric psychology. vol 44. issue 10. 2020-05-06. PMID:31393981. |
depression is linked to excess weight, insulin resistance, and type 2 diabetes (t2d). |
2020-05-06 |
2023-08-13 |
Not clear |
| Lauren D Gulley, Lauren B Shomaker, Nichole R Kelly, Kong Y Chen, Eric Stice, Cara H Olsen, Marian Tanofsky-Kraff, Jack A Yanovsk. Indirect Effects of a Cognitive-Behavioral Intervention on Adolescent Weight and Insulin Resistance Through Decreasing Depression in a Randomized Controlled Trial. Journal of pediatric psychology. vol 44. issue 10. 2020-05-06. PMID:31393981. |
we previously reported that in adolescent girls at-risk for t2d with moderately elevated depression, randomization to cognitive-behavioral therapy (cbt) produced greater decreases in depression at post-treament and greater decreases in fasting/2-h insulin at 1 year, compared to health education (he). |
2020-05-06 |
2023-08-13 |
Not clear |
| Lauren D Gulley, Lauren B Shomaker, Nichole R Kelly, Kong Y Chen, Eric Stice, Cara H Olsen, Marian Tanofsky-Kraff, Jack A Yanovsk. Indirect Effects of a Cognitive-Behavioral Intervention on Adolescent Weight and Insulin Resistance Through Decreasing Depression in a Randomized Controlled Trial. Journal of pediatric psychology. vol 44. issue 10. 2020-05-06. PMID:31393981. |
we examined whether decreasing depression explained intervention effects on body composition and insulin outcomes. |
2020-05-06 |
2023-08-13 |
Not clear |
| Olaitan J Jeremiah, Gráinne Cousins, Finbarr P Leacy, Brian P Kirby, Benedict K Rya. Evaluation of the effect of insulin sensitivity-enhancing lifestyle- and dietary-related adjuncts on antidepressant treatment response: protocol for a systematic review and meta-analysis. Systematic reviews. vol 8. issue 1. 2020-05-05. PMID:30803432. |
depression is the leading cause of disability worldwide and is known to be associated with insulin resistance (ir). |
2020-05-05 |
2023-08-13 |
Not clear |
| Olaitan J Jeremiah, Gráinne Cousins, Finbarr P Leacy, Brian P Kirby, Benedict K Rya. Evaluation of the effect of insulin sensitivity-enhancing lifestyle- and dietary-related adjuncts on antidepressant treatment response: protocol for a systematic review and meta-analysis. Systematic reviews. vol 8. issue 1. 2020-05-05. PMID:30803432. |
insulin resistance worsens the symptoms of depression and reduces the effectiveness of antidepressant medications in some depressed patients. |
2020-05-05 |
2023-08-13 |
Not clear |
| Shi Ke Zhang, Hui He, Wei Bin Gao, Xiao Ke Wu, Duo Jia Zhan. [Mechanism of transcutaneous auricular vagus nerve stimulation on polycystic ovary syndrome]. Zhen ci yan jiu = Acupuncture research. vol 45. issue 2. 2020-03-12. PMID:32144929. |
in the paper, the potential mechanism of the ta-vns in treatment of pcos is presented: 1)the ta-vns treats pcos by improving insulin resistance; 2)the ta-vns relieves pcos-induced psychological disorders through the treatment of depression; 3)the ta-vns is applicable in treatment of pcos complications, such as hypertension and diabetes. |
2020-03-12 |
2023-08-13 |
Not clear |
| Julia A Hamer, Daniela Testani, Rodrigo B Mansur, Yena Lee, Mehala Subramaniapillai, Roger S McIntyr. Brain insulin resistance: A treatment target for cognitive impairment and anhedonia in depression. Experimental neurology. vol 315. 2020-02-24. PMID:30695707. |
brain insulin resistance: a treatment target for cognitive impairment and anhedonia in depression. |
2020-02-24 |
2023-08-13 |
Not clear |
| Julia A Hamer, Daniela Testani, Rodrigo B Mansur, Yena Lee, Mehala Subramaniapillai, Roger S McIntyr. Brain insulin resistance: A treatment target for cognitive impairment and anhedonia in depression. Experimental neurology. vol 315. 2020-02-24. PMID:30695707. |
based on this evidence, it is possible that repurposing therapies approved for treating insulin resistance may be useful in treating cognitive and anhedonia symptoms in depression. |
2020-02-24 |
2023-08-13 |
Not clear |
| Sophia Frangou, Masoud Shirali, Mark J Adams, David M Howard, Jude Gibson, Lynsey S Hall, Blair H Smith, Sandosh Padmanabhan, Alison D Murray, David J Porteous, Chris S Haley, Ian J Deary, Toni-Kim Clarke, Andrew M McIntos. Insulin resistance: Genetic associations with depression and cognition in population based cohorts. Experimental neurology. vol 316. 2020-02-21. PMID:30965038. |
insulin resistance: genetic associations with depression and cognition in population based cohorts. |
2020-02-21 |
2023-08-13 |
Not clear |
| Sophia Frangou, Masoud Shirali, Mark J Adams, David M Howard, Jude Gibson, Lynsey S Hall, Blair H Smith, Sandosh Padmanabhan, Alison D Murray, David J Porteous, Chris S Haley, Ian J Deary, Toni-Kim Clarke, Andrew M McIntos. Insulin resistance: Genetic associations with depression and cognition in population based cohorts. Experimental neurology. vol 316. 2020-02-21. PMID:30965038. |
insulin resistance, broadly defined as the reduced ability of insulin to exert its biological action, has been associated with depression and cognitive dysfunction in observational studies. |
2020-02-21 |
2023-08-13 |
Not clear |
| Sophia Frangou, Masoud Shirali, Mark J Adams, David M Howard, Jude Gibson, Lynsey S Hall, Blair H Smith, Sandosh Padmanabhan, Alison D Murray, David J Porteous, Chris S Haley, Ian J Deary, Toni-Kim Clarke, Andrew M McIntos. Insulin resistance: Genetic associations with depression and cognition in population based cohorts. Experimental neurology. vol 316. 2020-02-21. PMID:30965038. |
specifically, we determined the association between quantitative measures of cognitive function and depression and genetic instruments of insulin resistance traits in two large-scale population samples, the generation scotland: scottish family health study (gs: sfhs; n = 19,994) and in the uk biobank (n = 331,374). |
2020-02-21 |
2023-08-13 |
Not clear |
| Sophia Frangou, Masoud Shirali, Mark J Adams, David M Howard, Jude Gibson, Lynsey S Hall, Blair H Smith, Sandosh Padmanabhan, Alison D Murray, David J Porteous, Chris S Haley, Ian J Deary, Toni-Kim Clarke, Andrew M McIntos. Insulin resistance: Genetic associations with depression and cognition in population based cohorts. Experimental neurology. vol 316. 2020-02-21. PMID:30965038. |
in the gs:sfhs, the polygenic risk score (prs) for fasting insulin was associated with verbal intelligence and depression while the prs for the homeostasis model assessment of insulin resistance was associated with verbal intelligence. |
2020-02-21 |
2023-08-13 |
Not clear |
| Sophia Frangou, Masoud Shirali, Mark J Adams, David M Howard, Jude Gibson, Lynsey S Hall, Blair H Smith, Sandosh Padmanabhan, Alison D Murray, David J Porteous, Chris S Haley, Ian J Deary, Toni-Kim Clarke, Andrew M McIntos. Insulin resistance: Genetic associations with depression and cognition in population based cohorts. Experimental neurology. vol 316. 2020-02-21. PMID:30965038. |
despite this overlap in genetic architecture, mendelian randomization analyses in the gs:sfhs and in the uk biobank samples did not yield evidence for causal associations from insulin resistance traits to either depression or cognition. |
2020-02-21 |
2023-08-13 |
Not clear |