| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| G A Bray, S Inoue, Y Nishizaw. Hypothalamic obesity : The autonomic hypothesis and the lateral hypothalamus. Diabetologia. vol 20. issue Suppl 1. 2017-08-23. PMID:27942824. |
when atropine and epinephrine were given to vmh lesioned rats, there was a significant depression in basal and glucose-stimulated levels of insulin. |
2017-08-23 |
2023-08-13 |
rat |
| Joshua J Joseph, Sherita H Golde. Cortisol dysregulation: the bidirectional link between stress, depression, and type 2 diabetes mellitus. Annals of the New York Academy of Sciences. vol 1391. issue 1. 2017-08-02. PMID:27750377. |
depression has been shown to increase the risk for progressive insulin resistance and incident type 2 diabetes mellitus in multiple studies, whereas the association of stress with diabetes is less clear, owing to differences in study designs and in forms and ascertainment of stress. |
2017-08-02 |
2023-08-13 |
Not clear |
| P W Franks, N Atabaki-Pasda. Causal inference in obesity research. Journal of internal medicine. vol 281. issue 3. 2017-06-26. PMID:27933671. |
in a systematic review of the literature in this field, we found: (i) probable causal relationships between adiposity and bone health/disease, cancers (colorectal, lung and kidney cancers), cardiometabolic traits (blood pressure, fasting insulin, inflammatory markers and lipids), uric acid concentrations, coronary heart disease and venous thrombosis (in the presence of pulmonary embolism), (ii) possible causal relationships between adiposity and gray matter volume, depression and common mental disorders, oesophageal cancer, macroalbuminuria, end-stage renal disease, diabetic kidney disease, nuclear cataract and gall stone disease, and (iii) no evidence for causal relationships between adiposity and alzheimer's disease, pancreatic cancer, venous thrombosis (in the absence of pulmonary embolism), liver function and periodontitis. |
2017-06-26 |
2023-08-13 |
Not clear |
| Liping Luo, Meilian Li. Adipose tissue in control of metabolism. The Journal of endocrinology. vol 231. issue 3. 2017-06-06. PMID:27935822. |
therefore, adipose tissue dysfunction plays a prominent role in the development of obesity and its related disorders such as insulin resistance, cardiovascular disease, diabetes, depression and cancer. |
2017-06-06 |
2023-08-13 |
Not clear |
| Yunhua Peng, Jing Liu, Le Shi, Ying Tang, Dan Gao, Jiangang Long, Jiankang Li. Mitochondrial dysfunction precedes depression of AMPK/AKT signaling in insulin resistance induced by high glucose in primary cortical neurons. Journal of neurochemistry. vol 137. issue 5. 2017-06-05. PMID:26926143. |
mitochondrial dysfunction precedes depression of ampk/akt signaling in insulin resistance induced by high glucose in primary cortical neurons. |
2017-06-05 |
2023-08-13 |
mouse |
| M I Maiorino, G Bellastella, E Della Volpe, O Casciano, L Scappaticcio, P Cirillo, D Giugliano, K Esposit. Erectile dysfunction in young men with type 1 diabetes. International journal of impotence research. vol 29. issue 1. 2017-05-10. PMID:27654032. |
compared with men without ed, diabetic men with ed showed lower weight, body mass index, fasting glucose, insulin dose and high-density lipoprotein cholesterol levels, and higher self-rating depression score (srds). |
2017-05-10 |
2023-08-13 |
human |
| C Weber, C T Schäff, U Kautzsch, S Börner, S Erdmann, R M Bruckmaier, M Röntgen, B Kuhla, H M Hammo. Variable liver fat concentration as a proxy for body fat mobilization postpartum has minor effects on insulin-induced changes in hepatic gene expression related to energy metabolism in dairy cows. Journal of dairy science. vol 100. issue 2. 2017-04-25. PMID:28012622. |
administration of insulin, albeit at a supraphysiological dose, was associated with inhibition of gene expression related to glucose production and β-oxidation, but we observed variable effects in the degree of insulin depression of individual genes. |
2017-04-25 |
2023-08-13 |
Not clear |
| James E Gangwisch, Raz Gross, Dolores Malaspin. Differential Associations Between Depression, Risk Factors for Insulin Resistance and Diabetes Incidence in a Large U.S. Sample. The Israel journal of psychiatry and related sciences. vol 52. issue 2. 2017-04-04. PMID:26431411. |
the associations between risk factors for insulin resistance and depression and diabetes can help determine the relative importance of factors that contribute toward the comorbidity. |
2017-04-04 |
2023-08-13 |
Not clear |
| Chao-Wei Huang, Tzu-Wen Hong, Ying-Jing Wang, Ko-Chien Chen, Ju-Chun Pei, Tai-Yuan Chuang, Wen-Sung Lai, Sheng-Hong Tsai, Richard Chu, Wei-Cheng Chen, Lee-Yan Sheen, Satoru Takahashi, Shih-Torng Ding, Tang-Long She. Ophiocordyceps formosana improves hyperglycemia and depression-like behavior in an STZ-induced diabetic mouse model. BMC complementary and alternative medicine. vol 16. issue 1. 2017-01-26. PMID:27553852. |
has been previously addressed to improve insulin insensitivity and improve the detrimental symptoms of depression; its mechanistic nature remains unsettled. |
2017-01-26 |
2023-08-13 |
mouse |
| Elizabeth A Vrany, Jessica M Berntson, Tasneem Khambaty, Jesse C Stewar. Depressive Symptoms Clusters and Insulin Resistance: Race/Ethnicity as a Moderator in 2005-2010 NHANES Data. Annals of behavioral medicine : a publication of the Society of Behavioral Medicine. vol 50. issue 1. 2016-10-31. PMID:26318593. |
although depression has been linked to insulin resistance, few studies have examined depressive symptom clusters. |
2016-10-31 |
2023-08-13 |
Not clear |
| Joseph Henson, David W Dunstan, Melanie J Davies, Thomas Yate. Sedentary behaviour as a new behavioural target in the prevention and treatment of type 2 diabetes. Diabetes/metabolism research and reviews. vol 32 Suppl 1. 2016-10-25. PMID:26813615. |
epidemiological evidence--from both cross-sectional and prospective observational studies--has indicated that the time spent in sedentary behaviour is a distinct risk factor for several health outcomes, including type 2 diabetes mellitus, insulin resistance, all-cause and cardiovascular disease mortality, depression and some types of cancer. |
2016-10-25 |
2023-08-13 |
Not clear |
| Yeshwant Kurhe, Radhakrishnan Mahes. Mechanisms linking depression co-morbid with obesity: An approach for serotonergic type 3 receptor antagonist as novel therapeutic intervention. Asian journal of psychiatry. vol 17. 2016-09-28. PMID:26243683. |
depression and obesity share some common pathological pathways such as hyperactivity of hypothalamic-pituitary-adrenal (hpa) axis, dysregulation of oxidant/antioxidant system balance, higher level of inflammatory cytokines, leptin resistance, altered plasma glucose, insulin resistance, reduced neuronal brain derived neurotrophic factor (bdnf) and decreased serotonergic neurotransmission in various regions of brain. |
2016-09-28 |
2023-08-13 |
Not clear |
| Fang-Yih Liaw, Tung-Wei Kao, Ju-Ting Hsueh, Yi-Hsin Chan, Yaw-Wen Chang, Wei-Liang Che. Exploring the Link between the Components of Metabolic Syndrome and the Risk of Depression. BioMed research international. vol 2015. 2016-09-21. PMID:26770976. |
this study aimed to evaluate whether mets components might contribute to depression in participants with insulin resistance (ir) or not. |
2016-09-21 |
2023-08-13 |
human |
| Sita Sharan Patel, Vineet Mehta, Harish Changotra, Malairaman Udayaban. Depression mediates impaired glucose tolerance and cognitive dysfunction: A neuromodulatory role of rosiglitazone. Hormones and behavior. vol 78. 2016-09-15. PMID:26631485. |
rosiglitazone (rosi) ameliorate cognitive deficit associated with depression and insulin resistance. |
2016-09-15 |
2023-08-13 |
mouse |
| Jenise C Wong, Lawrence M Dolan, Tony T Yang, Korey K Hoo. Insulin pump use and glycemic control in adolescents with type 1 diabetes: Predictors of change in method of insulin delivery across two years. Pediatric diabetes. vol 16. issue 8. 2016-09-02. PMID:25387433. |
few studies have explored durability of insulin pump use, and none have explored the link between depression and pump discontinuation. |
2016-09-02 |
2023-08-13 |
Not clear |
| Jenise C Wong, Lawrence M Dolan, Tony T Yang, Korey K Hoo. Insulin pump use and glycemic control in adolescents with type 1 diabetes: Predictors of change in method of insulin delivery across two years. Pediatric diabetes. vol 16. issue 8. 2016-09-02. PMID:25387433. |
to examine the relationship between depressive symptoms [measured by the children's depression inventory (cdi)], method of insulin delivery, and hemoglobin a1c (a1c), mixed models were used with data from 150 adolescents with type 1 diabetes (t1d) and visits every 6 months for 2 years. |
2016-09-02 |
2023-08-13 |
Not clear |
| Donatella Marazziti, Grazia Rutigliano, Stefano Baroni, Paola Landi, Liliana Dell'Oss. Metabolic syndrome and major depression. CNS spectrums. vol 19. issue 4. 2016-08-08. PMID:24103843. |
epidemiological studies have consistently demonstrated a co-occurrence of depression with mes components, ie, visceral obesity, dyslipidemia, insulin resistance, and hypertension. |
2016-08-08 |
2023-08-12 |
Not clear |
| Alexander Schäfer, Susanne Neschen, Melanie Kahle, Hakan Sarioglu, Tobias Gaisbauer, Axel Imhof, Jerzy Adamski, Stefanie M Hauck, Marius Ueffin. The Epoxyeicosatrienoic Acid Pathway Enhances Hepatic Insulin Signaling and is Repressed in Insulin-Resistant Mouse Liver. Molecular & cellular proteomics : MCP. vol 14. issue 10. 2016-07-28. PMID:26070664. |
the stimulation of insulin signaling by eets and depression of the pathway in insulin resistant liver suggest a likely role in hepatic insulin resistance. |
2016-07-28 |
2023-08-13 |
mouse |
| Kathleen Watson Lin, Tonita E Wroolie, Thalia Robakis, Natalie L Rasgo. Adjuvant pioglitazone for unremitted depression: Clinical correlates of treatment response. Psychiatry research. vol 230. issue 3. 2016-07-26. PMID:26602230. |
previous studies suggest that insulin-sensitizing agents could play a significant role in the treatment of major depression, particularly depression in patients with documented insulin resistance or those who are resistant to standard psychopharmacological approaches. |
2016-07-26 |
2023-08-13 |
Not clear |
| Kathleen Watson Lin, Tonita E Wroolie, Thalia Robakis, Natalie L Rasgo. Adjuvant pioglitazone for unremitted depression: Clinical correlates of treatment response. Psychiatry research. vol 230. issue 3. 2016-07-26. PMID:26602230. |
patients (n=37) with non-psychotic, non-remitting depression receiving standard psychiatric regimens for depression were randomized across an insulin sensitivity spectrum in a 12-week double blind, randomized controlled trial of pioglitazone or placebo. |
2016-07-26 |
2023-08-13 |
Not clear |