| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Katsutoshi Yokoyama, Takeshi Yamada, Hideaki Mitani, Sayaka Yamada, Shenghong Pu, Takehiko Yamanashi, Hiroshi Matsumura, Kazuyuki Nakagome, Koichi Kanek. Relationship between hypothalamic-pituitary-adrenal axis dysregulation and insulin resistance in elderly patients with depression. Psychiatry research. vol 226. issue 2-3. 2015-09-24. PMID:25757913. |
relationship between hypothalamic-pituitary-adrenal axis dysregulation and insulin resistance in elderly patients with depression. |
2015-09-24 |
2023-08-13 |
human |
| Haya Ascher-Svanum, Anthony Zagar, Dingfeng Jiang, Dara Schuster, Henry Schmitt, Ellen B Dennehy, David M Kendall, Joel Raskin, Robert J Hein. Associations Between Glycemic Control, Depressed Mood, Clinical Depression, and Diabetes Distress Before and After Insulin Initiation: An Exploratory, Post Hoc Analysis. Diabetes therapy : research, treatment and education of diabetes and related disorders. vol 6. issue 3. 2015-09-19. PMID:26159935. |
this exploratory, post hoc analysis investigated associations between depression parameters and glycemic control using data from a 24-month, prospective, observational, non-interventional study evaluating glycemic response following insulin initiation for t2dm. |
2015-09-19 |
2023-08-13 |
Not clear |
| Shang-Ying Tsai, Kuo-Hsuan Chung, Shou-Hung Huang, Pao-Huan Chen, Hsin-Chien Lee, Chian-Jue Ku. Persistent inflammation and its relationship to leptin and insulin in phases of bipolar disorder from acute depression to full remission. Bipolar disorders. vol 16. issue 8. 2015-08-19. PMID:25130211. |
persistent inflammation and its relationship to leptin and insulin in phases of bipolar disorder from acute depression to full remission. |
2015-08-19 |
2023-08-13 |
Not clear |
| Shang-Ying Tsai, Kuo-Hsuan Chung, Shou-Hung Huang, Pao-Huan Chen, Hsin-Chien Lee, Chian-Jue Ku. Persistent inflammation and its relationship to leptin and insulin in phases of bipolar disorder from acute depression to full remission. Bipolar disorders. vol 16. issue 8. 2015-08-19. PMID:25130211. |
we investigated alterations in inflammatory markers and their relationship with leptin and insulin levels in patients with phases of bipolar disorder from acute depression to full remission. |
2015-08-19 |
2023-08-13 |
Not clear |
| Igor A Pomytkin, Brandon H Cline, Daniel C Anthony, Harry W Steinbusch, Klaus-Peter Lesch, Tatyana Strekalov. Endotoxaemia resulting from decreased serotonin tranporter (5-HTT) function: a reciprocal risk factor for depression and insulin resistance? Behavioural brain research. vol 276. 2015-08-11. PMID:24815315. |
endotoxaemia resulting from decreased serotonin tranporter (5-htt) function: a reciprocal risk factor for depression and insulin resistance? |
2015-08-11 |
2023-08-13 |
mouse |
| Igor A Pomytkin, Brandon H Cline, Daniel C Anthony, Harry W Steinbusch, Klaus-Peter Lesch, Tatyana Strekalov. Endotoxaemia resulting from decreased serotonin tranporter (5-HTT) function: a reciprocal risk factor for depression and insulin resistance? Behavioural brain research. vol 276. 2015-08-11. PMID:24815315. |
we hypothesize that this leakage of bacterial endotoxins can activate both central and peripheral toll-like receptor 4 (tlr4), which inhibits insulin signaling and irs1/pi3k/akt and thus, contribute to the pathogenesis of diabetes and depression that are associated with this pathway. |
2015-08-11 |
2023-08-13 |
mouse |
| I V Kubasov, R S Arutyunyan, M G Dobretsov, A O Shpakov, E V Matrosov. [Effect of insulin on characteristics of contractile responses of fast and slow skeletal muscles of rats with streptozotocin-induced overt diabetes]. Zhurnal evoliutsionnoi biokhimii i fiziologii. vol 50. issue 2. 2015-08-10. PMID:25486817. |
insulin at a concentration of 10 nm did not produce essential effect on the time course of depression of responses in the course of development of fatigue at tetanic stimulation of m. edl and m. soleus both in control and in diabetic rats, but affected essentially the time course of change in duration of the half-decline (t(hd)) of their tetanic responses. |
2015-08-10 |
2023-08-13 |
rat |
| Sailas Benjamin, Priji Prakasan, Sajith Sreedharan, Andre-Denis G Wright, Friedrich Spene. Pros and cons of CLA consumption: an insight from clinical evidences. Nutrition & metabolism. vol 12. 2015-05-14. PMID:25972911. |
supposed adverse effects such as oxidative stress, insulin resistance, irritation of intestinal tract and milk fat depression are also examined. |
2015-05-14 |
2023-08-13 |
human |
| Arash ManafiRad, Farshad Farzadfar, Laleh Habibi, Morteza Azhdarzadeh, Haniyeh Aghaverdi, Khadijeh H Tehrani, Mina Lotfi, Patrick G Kehoe, Ali Sheidaei, Anoosheh Ghasemian, Ehsan Rezaei Darzi, Ramin Mahmoodi, Morteza Mahmoud. Is amyloid-β an innocent bystander and marker in Alzheimer's disease? Is the liability of multivalent cation homeostasis and its influence on amyloid-β function the real mechanism? Journal of Alzheimer's disease : JAD. vol 42. issue 1. 2015-05-11. PMID:24787921. |
the mid-life onset of chronic conditions (e.g., hypertension, diabetes, insulin intolerance, and depression nominated as risk factors for the later development of ad) points to the possibility that each condition could involve mechanisms, which while relatively modest over a short-term, could have significant accumulative effects. |
2015-05-11 |
2023-08-13 |
Not clear |
| Linda M McMullen, Kristjan J Sigurdso. Depression is to diabetes as antidepressants are to insulin: the unraveling of an analogy? Health communication. vol 29. issue 3. 2015-04-20. PMID:23631624. |
depression is to diabetes as antidepressants are to insulin: the unraveling of an analogy? |
2015-04-20 |
2023-08-12 |
human |
| Ana Claudia C de Ornelas Maia, Arthur de Azevedo Braga, Flávia Paes, Sérgio Machado, Antonio Egidio Nardi, Adriana Cardoso da Silv. Psychiatric comorbidity in diabetes type 1: a cross-sectional observational study. Revista da Associacao Medica Brasileira (1992). vol 60. issue 1. 2015-04-08. PMID:24918854. |
this study aims to investigate the prevalence of psychiatric disorders, i.e., the presence of signs and symptoms of anxiety and depression in type 1 diabetic patients, as well as to investigate the prevalence of psychiatric disorders in insulin dependent patients. |
2015-04-08 |
2023-08-13 |
Not clear |
| A W Austin, J L Gordon, K L Lavoie, A Arsenault, K Dasgupta, S L Baco. Differential association of insulin resistance with cognitive and somatic symptoms of depression. Diabetic medicine : a journal of the British Diabetic Association. vol 31. issue 8. 2015-03-30. PMID:24754892. |
differential association of insulin resistance with cognitive and somatic symptoms of depression. |
2015-03-30 |
2023-08-13 |
Not clear |
| B Li, R K Yadav, G S Jeong, H-R Kim, H-J Cha. The characteristics of Bax inhibitor-1 and its related diseases. Current molecular medicine. vol 14. issue 5. 2015-03-30. PMID:24894176. |
in other diseases, bi-1 has also been shown to regulate insulin resistance, adipocyte differentiation, hepatic dysfunction and depression. |
2015-03-30 |
2023-08-13 |
Not clear |
| Brandon H Cline, Joao P Costa-Nunes, Raymond Cespuglio, Natalyia Markova, Ana I Santos, Yury V Bukhman, Aslan Kubatiev, Harry W M Steinbusch, Klaus-Peter Lesch, Tatyana Strekalov. Dicholine succinate, the neuronal insulin sensitizer, normalizes behavior, REM sleep, hippocampal pGSK3 beta and mRNAs of NMDA receptor subunits in mouse models of depression. Frontiers in behavioral neuroscience. vol 9. 2015-03-13. PMID:25767439. |
dicholine succinate, the neuronal insulin sensitizer, normalizes behavior, rem sleep, hippocampal pgsk3 beta and mrnas of nmda receptor subunits in mouse models of depression. |
2015-03-13 |
2023-08-13 |
mouse |
| Brandon H Cline, Joao P Costa-Nunes, Raymond Cespuglio, Natalyia Markova, Ana I Santos, Yury V Bukhman, Aslan Kubatiev, Harry W M Steinbusch, Klaus-Peter Lesch, Tatyana Strekalov. Dicholine succinate, the neuronal insulin sensitizer, normalizes behavior, REM sleep, hippocampal pGSK3 beta and mRNAs of NMDA receptor subunits in mouse models of depression. Frontiers in behavioral neuroscience. vol 9. 2015-03-13. PMID:25767439. |
central insulin receptor-mediated signaling is attracting the growing attention of researchers because of rapidly accumulating evidence implicating it in the mechanisms of plasticity, stress response, and neuropsychiatric disorders including depression. |
2015-03-13 |
2023-08-13 |
mouse |
| Brandon H Cline, Joao P Costa-Nunes, Raymond Cespuglio, Natalyia Markova, Ana I Santos, Yury V Bukhman, Aslan Kubatiev, Harry W M Steinbusch, Klaus-Peter Lesch, Tatyana Strekalov. Dicholine succinate, the neuronal insulin sensitizer, normalizes behavior, REM sleep, hippocampal pGSK3 beta and mRNAs of NMDA receptor subunits in mouse models of depression. Frontiers in behavioral neuroscience. vol 9. 2015-03-13. PMID:25767439. |
compounds enhancing neuronal insulin receptor-mediated transmission exert an antidepressant-like effect in several pre-clinical paradigms of depression; similarly, such properties for ds were found with a stress-induced anhedonia model. |
2015-03-13 |
2023-08-13 |
mouse |
| Adam G Tabák, Tasnime N Akbaraly, G David Batty, Mika Kivimäk. Depression and type 2 diabetes: a causal association? The lancet. Diabetes & endocrinology. vol 2. issue 3. 2015-02-23. PMID:24622754. |
the evidence for an association between depression and glycaemic traits (eg, glucose, insulin, insulin sensitivity, and insulin secretion) is also mixed. |
2015-02-23 |
2023-08-12 |
Not clear |
| David E Kemp, Martha Schinagle, Keming Gao, Carla Conroy, Stephen J Ganocy, Faramarz Ismail-Beigi, Joseph R Calabres. PPAR-γ agonism as a modulator of mood: proof-of-concept for pioglitazone in bipolar depression. CNS drugs. vol 28. issue 6. 2015-01-22. PMID:24715548. |
insulin resistance and other cardio-metabolic risk factors predict increased risk of depression and decreased response to antidepressant and mood stabilizer treatments. |
2015-01-22 |
2023-08-13 |
Not clear |
| Deepali Gupta, Yeshwant Kurhe, Mahesh Radhakrishna. Antidepressant effects of insulin in streptozotocin induced diabetic mice: Modulation of brain serotonin system. Physiology & behavior. vol 129. 2014-12-15. PMID:24582678. |
insulin is believed to have antidepressant effects in depression associated with diabetes; however, the mechanism underlying the postulated effect is poorly understood. |
2014-12-15 |
2023-08-12 |
mouse |
| Deepali Gupta, Yeshwant Kurhe, Mahesh Radhakrishna. Antidepressant effects of insulin in streptozotocin induced diabetic mice: Modulation of brain serotonin system. Physiology & behavior. vol 129. 2014-12-15. PMID:24582678. |
collectively, the data indicate that insulin exhibits antidepressant effects in depression associated with stz induced diabetes in mice through the elevation of the brain serotonin levels. |
2014-12-15 |
2023-08-12 |
mouse |