| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Suk Yu Yau, Ang Li, Aimin Xu, Kwok-Fai S. Fat cell-secreted adiponectin mediates physical exercise-induced hippocampal neurogenesis: an alternative anti-depressive treatment? Neural regeneration research. vol 10. issue 1. 2015-03-19. PMID:25788905. |
here, we briefly review these novel findings and discuss the possibility of counteracting depression by modulating adiponectin signaling in the hippocampus with interventions including physical exercise and administration of pharmacological agents. |
2015-03-19 |
2023-08-13 |
Not clear |
| Brandon H Cline, Joao P Costa-Nunes, Raymond Cespuglio, Natalyia Markova, Ana I Santos, Yury V Bukhman, Aslan Kubatiev, Harry W M Steinbusch, Klaus-Peter Lesch, Tatyana Strekalov. Dicholine succinate, the neuronal insulin sensitizer, normalizes behavior, REM sleep, hippocampal pGSK3 beta and mRNAs of NMDA receptor subunits in mouse models of depression. Frontiers in behavioral neuroscience. vol 9. 2015-03-13. PMID:25767439. |
dicholine succinate, the neuronal insulin sensitizer, normalizes behavior, rem sleep, hippocampal pgsk3 beta and mrnas of nmda receptor subunits in mouse models of depression. |
2015-03-13 |
2023-08-13 |
mouse |
| Wentao Fan, Qian Wang, Yongmei Ya. Influence of Xingnao Jieyu capsule on hippocampal and frontal lobe neuronal growth in a rat model of post-stroke depression. Neural regeneration research. vol 7. issue 3. 2015-03-13. PMID:25767497. |
influence of xingnao jieyu capsule on hippocampal and frontal lobe neuronal growth in a rat model of post-stroke depression. |
2015-03-13 |
2023-08-13 |
rat |
| Wentao Fan, Qian Wang, Yongmei Ya. Influence of Xingnao Jieyu capsule on hippocampal and frontal lobe neuronal growth in a rat model of post-stroke depression. Neural regeneration research. vol 7. issue 3. 2015-03-13. PMID:25767497. |
after intragastric perfusion with 45 mg/100 g, 15 mg/100 g, and 7.5 mg/100 g of xingnao jieyu for 7, 14 and 21 days, neuronal morphology in the frontal lobe and hippocampus was improved, depression state and voluntary behaviors were also effectively improved in rats with post-stroke depression. |
2015-03-13 |
2023-08-13 |
rat |
| Shuang Liang, Renbin Huang, Xing Lin, Jianchun Huang, Zhongshi Huang, Huagang Li. Effects of Yulangsan polysaccharide on monoamine neurotransmitters, adenylate cyclase activity and brain-derived neurotrophic factor expression in a mouse model of depression induced by unpredictable chronic mild stress. Neural regeneration research. vol 7. issue 3. 2015-03-13. PMID:25767498. |
our results indicate that ylsps inhibits depression by upregulating monoamine neurotransmitters, prefrontal cortex adenylate cyclase activity and hippocampal brain-derived neurotrophic factor expression. |
2015-03-13 |
2023-08-13 |
mouse |
| R Kohen, A Dobra, J H Tracy, E Hauge. Transcriptome profiling of human hippocampus dentate gyrus granule cells in mental illness. Translational psychiatry. vol 4. 2015-03-06. PMID:24594777. |
we investigated the transcriptome of dentate gyrus (dg) granule cells in postmortem human hippocampus in 79 subjects with mental illness (schizophrenia, bipolar disorder, major depression) and nonpsychiatric controls. |
2015-03-06 |
2023-08-12 |
human |
| Bruno Dietsche, Heidelore Backes, Mirjam Stratmann, Carsten Konrad, Tilo Kircher, Axel Kru. Altered neural function during episodic memory encoding and retrieval in major depression. Human brain mapping. vol 35. issue 9. 2015-03-06. PMID:24639328. |
while a strong association between hippocampal and parahippocampal activation during memory encoding with subsequent memory performance became evident in healthy controls, this relationship was absent in patients with depression. |
2015-03-06 |
2023-08-12 |
human |
| Martin Dokter, Oliver von Bohlen und Halbac. Neurogenesis within the adult hippocampus under physiological conditions and in depression. Neural regeneration research. vol 7. issue 7. 2015-03-06. PMID:25745444. |
neurogenesis within the adult hippocampus under physiological conditions and in depression. |
2015-03-06 |
2023-08-13 |
Not clear |
| Martin Dokter, Oliver von Bohlen und Halbac. Neurogenesis within the adult hippocampus under physiological conditions and in depression. Neural regeneration research. vol 7. issue 7. 2015-03-06. PMID:25745444. |
based on that, it can be speculated that factors, which directly or indirectly increase the rate of hippocampal neurogenesis, may be helpful in the treatment of depression. |
2015-03-06 |
2023-08-13 |
Not clear |
| Yuan Hu, Xiao-Jiang Zhou, Ping Liu, Xian-Zhe Dong, Li-Hua Mu, Yi-Bang Chen, Ming-Yue Liu, Bing-Ying Y. Antidepressant and neuroprotective effect of the Chinese herb kaixinsan against lentiviral shRNA knockdown brain-derived neurotrophic factor-induced injury in vitro and in vivo. Neuropsychobiology. vol 69. issue 3. 2015-02-26. PMID:24776773. |
depression has been associated with reduced expression of brain-derived neurotrophic factor (bdnf) in the hippocampus. |
2015-02-26 |
2023-08-13 |
Not clear |
| Yuan Hu, Xiao-Jiang Zhou, Ping Liu, Xian-Zhe Dong, Li-Hua Mu, Yi-Bang Chen, Ming-Yue Liu, Bing-Ying Y. Antidepressant and neuroprotective effect of the Chinese herb kaixinsan against lentiviral shRNA knockdown brain-derived neurotrophic factor-induced injury in vitro and in vivo. Neuropsychobiology. vol 69. issue 3. 2015-02-26. PMID:24776773. |
using bdnf knockdown mediated by lentiviral vectors (lv-shbdnf-3) transfected with primary hippocampal neurons and following injection into the dentate gyrus of the hippocampus, it was demonstrated that a reduction in bdnf expression affects cell viability and animal behaviours associated with depression. |
2015-02-26 |
2023-08-13 |
Not clear |
| Su-Su Tang, Miao-jin Ji, Lan Chen, Mei Hu, Yan Long, Yong-qi Li, Ming-xing Miao, Jia-chang Li, Ning Li, Hui Ji, Xi-jing Chen, Hao Hon. Protective effect of pranlukast on Aβ₁₋₄₂-induced cognitive deficits associated with downregulation of cysteinyl leukotriene receptor 1. The international journal of neuropsychopharmacology. vol 17. issue 4. 2015-02-12. PMID:24229499. |
we found that bilateral intrahippocampal injection of aβ₁₋₄₂ resulted in a significant decline of spatial learning and memory of mice in the morris water maze (mwm) and y-maze tests, together with a serious depression of in vivo hippocampal long-term potentiation (ltp) in the ca1 region of the mice. |
2015-02-12 |
2023-08-12 |
mouse |
| Roberto Fiore, Marek Rajman, Chrysovalandis Schwale, Silvia Bicker, Anna Antoniou, Claus Bruehl, Andreas Draguhn, Gerhard Schrat. MiR-134-dependent regulation of Pumilio-2 is necessary for homeostatic synaptic depression. The EMBO journal. vol 33. issue 19. 2015-02-12. PMID:25097251. |
here, we describe a sequential homeostatic synaptic depression mechanism in primary hippocampal neurons involving mirna-dependent translational regulation. |
2015-02-12 |
2023-08-13 |
Not clear |
| Lian-Shun Zheng, Naoko Kaneko, Kazunobu Sawamot. Minocycline treatment ameliorates interferon-alpha- induced neurogenic defects and depression-like behaviors in mice. Frontiers in cellular neuroscience. vol 9. 2015-02-12. PMID:25674053. |
neural stem cells (nscs) in the hippocampus continuously generate new neurons, and some evidence suggests that decreased neurogenesis plays a role in the neuropathology of depression. |
2015-02-12 |
2023-08-13 |
mouse |
| Adam Sierakowiak, Anna Mattsson, Marta Gómez-Galán, Teresa Feminía, Lisette Graae, Sahar Nikkhou Aski, Peter Damberg, Mia Lindskog, Stefan Brené, Elin Åber. Hippocampal morphology in a rat model of depression: the effects of physical activity. The open neuroimaging journal. vol 9. 2015-02-12. PMID:25674191. |
hippocampal morphology in a rat model of depression: the effects of physical activity. |
2015-02-12 |
2023-08-13 |
rat |
| Adam Sierakowiak, Anna Mattsson, Marta Gómez-Galán, Teresa Feminía, Lisette Graae, Sahar Nikkhou Aski, Peter Damberg, Mia Lindskog, Stefan Brené, Elin Åber. Hippocampal morphology in a rat model of depression: the effects of physical activity. The open neuroimaging journal. vol 9. 2015-02-12. PMID:25674191. |
accumulating in vivo and ex vivo evidences show that humans suffering from depression have decreased hippocampal volume and altered spine density. |
2015-02-12 |
2023-08-13 |
rat |
| Adam Sierakowiak, Anna Mattsson, Marta Gómez-Galán, Teresa Feminía, Lisette Graae, Sahar Nikkhou Aski, Peter Damberg, Mia Lindskog, Stefan Brené, Elin Åber. Hippocampal morphology in a rat model of depression: the effects of physical activity. The open neuroimaging journal. vol 9. 2015-02-12. PMID:25674191. |
moreover, physical activity has an antidepressant effect in humans and in animal models, but to what extent physical activity can affect hippocampal volume and spine numbers in a model for depression is not known. |
2015-02-12 |
2023-08-13 |
rat |
| L Gerritsen, M Rijpkema, I van Oostrom, J Buitelaar, B Franke, G Fernández, I Tendolka. Amygdala to hippocampal volume ratio is associated with negative memory bias in healthy subjects. Psychological medicine. vol 42. issue 2. 2015-02-09. PMID:21740626. |
here, we studied whether memory bias is related to amygdala and hippocampal volume, two structures that are critical for emotional memory processes and that show consistent volume alterations in depression. |
2015-02-09 |
2023-08-12 |
human |
| Shaoqiong Chen, Lisha Lai, Zhuang Kang, Xiao Luo, Jiansheng Zhang, Jianfang L. Imaging changes in neural circuits in patients with depression using (1)H-magnetic resonance spectroscopy and diffusion tensor imaging. Neural regeneration research. vol 7. issue 24. 2015-01-27. PMID:25624814. |
compared with the control group, the mild depressed patients had: (1) a higher choline/creatine ratio and a negative correlation between the choline/creatine ratio and the average diffusion coefficient in the hippocampus; (2) a lower choline/creatine ratio and a higher fractional anisotropy in the striatum; (3) a lower fractional anisotropy and a positive correlation between the fractional anisotropy and the choline/creatine ratio in the prefrontal deep white matter; and (4) a higher average diffusion coefficient and a positive correlation between the choline/creatine ratio and the n-acetylaspartate/creatine ratio in the thalamus, as well as positive correlation between the choline/creatine ratio and hamilton depression scores. |
2015-01-27 |
2023-08-13 |
Not clear |
| J C González, G Lignani, M Maroto, P Baldelli, J M Hernández-Guij. Presynaptic muscarinic receptors reduce synaptic depression and facilitate its recovery at hippocampal GABAergic synapses. Cerebral cortex (New York, N.Y. : 1991). vol 24. issue 7. 2015-01-23. PMID:23425889. |
presynaptic muscarinic receptors reduce synaptic depression and facilitate its recovery at hippocampal gabaergic synapses. |
2015-01-23 |
2023-08-12 |
Not clear |