| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| V Bhagya, B N Srikumar, T R Raju, B S Shankaranarayana Ra. The selective noradrenergic reuptake inhibitor reboxetine restores spatial learning deficits, biochemical changes, and hippocampal synaptic plasticity in an animal model of depression. Journal of neuroscience research. vol 93. issue 1. 2015-07-08. PMID:25146499. |
the selective noradrenergic reuptake inhibitor reboxetine restores spatial learning deficits, biochemical changes, and hippocampal synaptic plasticity in an animal model of depression. |
2015-07-08 |
2023-08-13 |
rat |
| V Bhagya, B N Srikumar, T R Raju, B S Shankaranarayana Ra. The selective noradrenergic reuptake inhibitor reboxetine restores spatial learning deficits, biochemical changes, and hippocampal synaptic plasticity in an animal model of depression. Journal of neuroscience research. vol 93. issue 1. 2015-07-08. PMID:25146499. |
previously, we showed altered hippocampal synaptic plasticity in an animal model of depression. |
2015-07-08 |
2023-08-13 |
rat |
| Lian-Shun Zheng, Seiji Hitoshi, Naoko Kaneko, Keizo Takao, Tsuyoshi Miyakawa, Yasuhito Tanaka, Hongjing Xia, Ulrich Kalinke, Koutaro Kudo, Shigenobu Kanba, Kazuhiro Ikenaka, Kazunobu Sawamot. Mechanisms for interferon-α-induced depression and neural stem cell dysfunction. Stem cell reports. vol 3. issue 1. 2015-07-06. PMID:25068123. |
brain-specific mouse knockout of the ifn-α receptor prevented ifn-α-induced depressive behavioral phenotypes and the inhibition of neurogenesis, suggesting that ifn-α suppresses hippocampal neurogenesis and induces depression via its receptor in the brain. |
2015-07-06 |
2023-08-13 |
mouse |
| Kelly Rowe Bijanki, Brendan Hodis, Michael C Brumm, Emily L Harlynn, Laurie M McCormic. Hippocampal and left subcallosal anterior cingulate atrophy in psychotic depression. PloS one. vol 9. issue 10. 2015-07-03. PMID:25338068. |
hippocampal and left subcallosal anterior cingulate atrophy in psychotic depression. |
2015-07-03 |
2023-08-13 |
Not clear |
| Kelly Rowe Bijanki, Brendan Hodis, Michael C Brumm, Emily L Harlynn, Laurie M McCormic. Hippocampal and left subcallosal anterior cingulate atrophy in psychotic depression. PloS one. vol 9. issue 10. 2015-07-03. PMID:25338068. |
previous imaging studies have identified abnormal volumes of the hippocampus, amygdala, and subcallosal region of the anterior cingulate cortex (scacc) in psychotic depression, though studies have not yet examined the role of family history of depression in these relationships. |
2015-07-03 |
2023-08-13 |
Not clear |
| Miyeon Choi, Sung Eun Wang, Seung Yeon Ko, Hyo Jung Kang, Seung Yeun Chae, Seung Hoon Lee, Yong-Seok Kim, Ronald S Duman, Hyeon So. Overexpression of human GATA-1 and GATA-2 interferes with spine formation and produces depressive behavior in rats. PloS one. vol 9. issue 10. 2015-06-25. PMID:25340772. |
we also examined the influence of aav-hgata1 and aav-hgata2 infusions into the dorsal hippocampus on rodent behavior in models of depression. |
2015-06-25 |
2023-08-13 |
human |
| Xingxiao Gao, Peng Sun, Mingqi Qiao, Sheng Wei, Ling Xue, Huiyun Zhan. Shu‑Yu capsule, a Traditional Chinese Medicine formulation, attenuates premenstrual syndrome depression induced by chronic stress constraint. Molecular medicine reports. vol 10. issue 6. 2015-06-19. PMID:25270424. |
furthermore, syc inhibited the decrease of the glu/gaba ratio in the hippocampus of rats with pms depression. |
2015-06-19 |
2023-08-13 |
rat |
| Marissa E Maheu, Julia Devorak, Alexander Freibauer, Maria Antonietta Davoli, Gustavo Turecki, Naguib Mechawa. Increased doublecortin (DCX) expression and incidence of DCX-immunoreactive multipolar cells in the subventricular zone-olfactory bulb system of suicides. Frontiers in neuroanatomy. vol 9. 2015-06-17. PMID:26082689. |
postmortem studies have confirmed the occurrence of adult hippocampal neurogenesis in humans and implicated this process in antidepressant response, yet neurogenesis in other regions remains to be examined in the context of depression. |
2015-06-17 |
2023-08-13 |
Not clear |
| Li-Juan Zhu, Meng-Ying Liu, Huan Li, Xiao Liu, Chen Chen, Zhou Han, Hai-Yin Wu, Xing Jing, Hai-Hui Zhou, Hoonkyo Suh, Dong-Ya Zhu, Qi-Gang Zho. The different roles of glucocorticoids in the hippocampus and hypothalamus in chronic stress-induced HPA axis hyperactivity. PloS one. vol 9. issue 5. 2015-06-15. PMID:24831808. |
this study suggests that the glucocorticoids in the hippocampus play an important role in the development of hpa axis hyperactivity and the glucocorticoids in the hypothalamus can't induce hyperactivity of hpa axis, revealing new insights into understanding the mechanism of depression. |
2015-06-15 |
2023-08-13 |
Not clear |
| Kiarash Riazi, Michael A Galic, Amanda C Kentner, Aylin Y Reid, Keith A Sharkey, Quentin J Pittma. Microglia-dependent alteration of glutamatergic synaptic transmission and plasticity in the hippocampus during peripheral inflammation. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 35. issue 12. 2015-06-15. PMID:25810524. |
both long-term potentiation (ltp) and depression (ltd) were significantly reduced in hippocampal slices taken from inflamed animals. |
2015-06-15 |
2023-08-13 |
rat |
| Melanie Föcking, Rianne Opstelten, Jos Prickaerts, Harry W M Steinbusch, Michael J Dunn, Daniël L A van den Hove, David R Cotte. Proteomic investigation of the hippocampus in prenatally stressed mice implicates changes in membrane trafficking, cytoskeletal, and metabolic function. Developmental neuroscience. vol 36. issue 5. 2015-06-10. PMID:25138076. |
the hippocampus is particularly sensitive to prenatal stress, and robust abnormalities have been described in the hippocampus in schizophrenia and depression. |
2015-06-10 |
2023-08-13 |
mouse |
| Christina L Nemeth, Erica R Glasper, Constance S Harrell, Sanjana A Malviya, Jeffrey S Otis, Gretchen N Neig. Meloxicam blocks neuroinflammation, but not depressive-like behaviors, in HIV-1 transgenic female rats. PloS one. vol 9. issue 10. 2015-06-10. PMID:25271421. |
together, these data support a biological basis for the co-morbid manifestation of depression in hiv-positive patients as early as in adolescence and suggest that modifications in behavior manifest independent of inflammatory activity in the hippocampus. |
2015-06-10 |
2023-08-13 |
human |
| Xiao Huang, Yue-Shi Mao, Chao Li, Hao Wang, Jian-Lin J. Venlafaxine inhibits apoptosis of hippocampal neurons by up-regulating brain-derived neurotrophic factor in a rat depression model. International journal of clinical and experimental pathology. vol 7. issue 8. 2015-06-09. PMID:25197330. |
venlafaxine inhibits apoptosis of hippocampal neurons by up-regulating brain-derived neurotrophic factor in a rat depression model. |
2015-06-09 |
2023-08-13 |
rat |
| Yea-Hyun Leem, Sang-Sun Yoon, Yu-Han Kim, Sangmee Ahn J. Disrupted MEK/ERK signaling in the medial orbital cortex and dorsal endopiriform nuclei of the prefrontal cortex in a chronic restraint stress mouse model of depression. Neuroscience letters. vol 580. 2015-06-08. PMID:25116759. |
however, studies on mek/erk signaling in depression have only been done in a few brain regions, such as the hippocampus and mesolimbic reward pathways. |
2015-06-08 |
2023-08-13 |
mouse |
| Xiao Huang, Yue-Shi Mao, Chao Li, Hao Wang, Jian-Lin J. Venlafaxine inhibits apoptosis of hippocampal neurons by up-regulating brain-derived neurotrophic factor in a rat depression model. Die Pharmazie. vol 69. issue 12. 2015-06-02. PMID:25951665. |
venlafaxine inhibits apoptosis of hippocampal neurons by up-regulating brain-derived neurotrophic factor in a rat depression model. |
2015-06-02 |
2023-08-13 |
rat |
| Christina R Tyler, Benjamin R Solomon, Adam L Ulibarri, Andrea M Alla. Fluoxetine treatment ameliorates depression induced by perinatal arsenic exposure via a neurogenic mechanism. Neurotoxicology. vol 44. 2015-05-27. PMID:24952232. |
we have previously demonstrated that developmental exposure to low amounts of arsenic induces depression in adulthood along with several morphological and molecular aberrations, particularly associated with the hippocampus and the hypothalamic-pituitary-adrenal (hpa) axis. |
2015-05-27 |
2023-08-13 |
Not clear |
| Masayoshi Mori, Yusuke Murata, Asami Matsuo, Tomoyo Takemoto, Kazunori Min. Chronic Treatment with the 5-HT1A Receptor Partial Agonist Tandospirone Increases Hippocampal Neurogenesis. Neurology and therapy. vol 3. issue 1. 2015-05-22. PMID:26000223. |
adult hippocampal neurogenesis has been proposed to be important for understanding and treating depression and anxiety. |
2015-05-22 |
2023-08-13 |
human |
| Mohamed Ghilan, Crystal A Bostrom, Brett N Hryciw, Jessica M Simpson, Brian R Christie, Joana Gil-Mohape. YAC128 Huntington's disease transgenic mice show enhanced short-term hippocampal synaptic plasticity early in the course of the disease. Brain research. vol 1581. 2015-05-21. PMID:24949563. |
we show that the yac128 hippocampal dentate gyrus (dg) displays marked reductions in paired-pulse depression both at 3 and 6 months of age. |
2015-05-21 |
2023-08-13 |
mouse |
| Hui Liu, Li-Min Wen, Hui Qiao, Shu-Cheng A. [Modulation of hippocampal glutamate and NMDA/AMPA receptor by homocysteine in chronic unpredictable mild stress-induced rat depression]. Sheng li xue bao : [Acta physiologica Sinica]. vol 65. issue 1. 2015-05-16. PMID:23426515. |
[modulation of hippocampal glutamate and nmda/ampa receptor by homocysteine in chronic unpredictable mild stress-induced rat depression]. |
2015-05-16 |
2023-08-12 |
rat |
| Hui Liu, Li-Min Wen, Hui Qiao, Shu-Cheng A. [Modulation of hippocampal glutamate and NMDA/AMPA receptor by homocysteine in chronic unpredictable mild stress-induced rat depression]. Sheng li xue bao : [Acta physiologica Sinica]. vol 65. issue 1. 2015-05-16. PMID:23426515. |
the study was to investigate the role of homocysteine (hcy) which was released by hippocampal glial cells and its relationship with nmda receptor and ampa receptor in depression induced by chronic unpredictable mild stress (cums), and explore the mechanism of changes of glu/glu receptor in glial cells and neurons. |
2015-05-16 |
2023-08-12 |
rat |