| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Aditya Asokan, Alan R Ball, Christina D Laird, Linda Hermer, Brandi K Ormero. Desvenlafaxine may accelerate neuronal maturation in the dentate gyri of adult male rats. PloS one. vol 9. issue 6. 2015-08-18. PMID:24896246. |
these data support the hypothesis that hippocampal neurogenesis may indeed serve as a biomarker of depression and the effects of antidepressant treatment, and may be informative for developing novel fast-acting antidepressant strategies. |
2015-08-18 |
2023-08-13 |
rat |
| YuHong Wang, Hui Yang, Wei Li, Pan Meng, YuanShan Han, Xiuli Zhang, DeLiang Cao, Yuansheng Ta. Zuogui Jiangtang Jieyu Formulation Prevents Hyperglycaemia and Depressive-Like Behaviour in Rats by Reducing the Glucocorticoid Level in Plasma and Hippocampus. Evidence-based complementary and alternative medicine : eCAM. vol 2015. 2015-08-14. PMID:26273311. |
zgjtjy inhibits the expression of 11β-hsd1 and increases gr in hippocampus and subsequently modulates blood glucose levels, and therefore it is potential property that zgjtjy could be of benefit for the treatment of behavior and cognitive function of diabetes-related depression. |
2015-08-14 |
2023-08-13 |
rat |
| Ankur Jindal, Radhakrishnan Mahesh, Shvetank Bhat. Etazolate, a phosphodiesterase-4 enzyme inhibitor produces antidepressant-like effects by blocking the behavioral, biochemical, neurobiological deficits and histological abnormalities in hippocampus region caused by olfactory bulbectomy. Psychopharmacology. vol 232. issue 3. 2015-08-11. PMID:25120105. |
our earlier studies demonstrated that etazolate produced antidepressant-like effects in behavioral despair models of depression; however, the potential role of etazolate on behavior and morphological changes in the hippocampus region along with its underlying mechanism(s) following obx has not been adequately addressed. |
2015-08-11 |
2023-08-13 |
Not clear |
| Zhen Zhang, Wei Wang, Peng Zhong, Sarah J Liu, Jonathan Z Long, Li Zhao, Hai-Qing Gao, Benjamin F Cravatt, Qing-Song Li. Blockade of 2-arachidonoylglycerol hydrolysis produces antidepressant-like effects and enhances adult hippocampal neurogenesis and synaptic plasticity. Hippocampus. vol 25. issue 1. 2015-08-11. PMID:25131612. |
adult hippocampal neurogenesis has been implicated in animal models of anxiety and depression and behavioral effects of antidepressants. |
2015-08-11 |
2023-08-13 |
mouse |
| Mikkel V Olesen, Gitta Wörtwein, Bente Pakkenber. Electroconvulsive stimulation, but not chronic restraint stress, causes structural alterations in adult rat hippocampus--a stereological study. Hippocampus. vol 25. issue 1. 2015-08-11. PMID:25139647. |
only a few previous studies have used validated stereological methods to test how stress and animal paradigms of depression affect adult hippocampal neurogenesis and whether antidepressant therapy can counteract possible changes in an animal model. |
2015-08-11 |
2023-08-13 |
rat |
| Mikkel V Olesen, Gitta Wörtwein, Bente Pakkenber. Electroconvulsive stimulation, but not chronic restraint stress, causes structural alterations in adult rat hippocampus--a stereological study. Hippocampus. vol 25. issue 1. 2015-08-11. PMID:25139647. |
using a validated rat model of depression in combination with a clinically relevant schedule of electroconvulsive stimulation, we estimated the total number of newly formed neurons in the hippocampal subgranular zone. |
2015-08-11 |
2023-08-13 |
rat |
| Shahbaz Ali Khan, Vssr Ryali, Pookala Shivaram Bhat, Jyoti Prakash, Kalpana Srivastava, Shagufta Khana. The hippocampus and executive functions in depression. Industrial psychiatry journal. vol 24. issue 1. 2015-08-10. PMID:26257478. |
the hippocampus and executive functions in depression. |
2015-08-10 |
2023-08-13 |
Not clear |
| Hideaki Suzuki, Akira Sumiyoshi, Yasuharu Matsumoto, Ben A Duffy, Takeo Yoshikawa, Mark F Lythgoe, Kazuhiko Yanai, Yasuyuki Taki, Ryuta Kawashima, Hiroaki Shimokaw. Structural abnormality of the hippocampus associated with depressive symptoms in heart failure rats. NeuroImage. vol 105. 2015-08-05. PMID:25462699. |
structural abnormalities of the ventral hippocampus have been observed in depression but have never been reported in hf. |
2015-08-05 |
2023-08-13 |
rat |
| Carol E Vásquez, Romina Riener, Elaine Reynolds, Gabrielle B Britto. NMDA receptor dysregulation in chronic state: a possible mechanism underlying depression with BDNF downregulation. Neurochemistry international. vol 79. 2015-08-04. PMID:25277075. |
evidence from animal models of depression demonstrates that chronic stress impairs hippocampal bdnf expression and that antidepressant drug effects correlate with increased bdnf synthesis and activity in the hippocampus. |
2015-08-04 |
2023-08-13 |
human |
| Sinead M O'Donovan, Shane O'Mara, Michael J Dunn, Declan M McLoughli. The persisting effects of electroconvulsive stimulation on the hippocampal proteome. Brain research. vol 1593. 2015-08-04. PMID:25451099. |
electroconvulsive stimulation (ecs), the animal analogue of ect, was administered to rats to determine the proteomic changes induced in the hippocampus, a region of the brain implicated in the biology of depression and its treatment. |
2015-08-04 |
2023-08-13 |
rat |
| Warren D Taylor, Douglas R McQuoid, Martha E Payne, Anthony S Zannas, James R MacFall, David C Steffen. Hippocampus atrophy and the longitudinal course of late-life depression. The American journal of geriatric psychiatry : official journal of the American Association for Geriatric Psychiatry. vol 22. issue 12. 2015-08-03. PMID:24378256. |
hippocampus atrophy and the longitudinal course of late-life depression. |
2015-08-03 |
2023-08-12 |
Not clear |
| Warren D Taylor, Douglas R McQuoid, Martha E Payne, Anthony S Zannas, James R MacFall, David C Steffen. Hippocampus atrophy and the longitudinal course of late-life depression. The American journal of geriatric psychiatry : official journal of the American Association for Geriatric Psychiatry. vol 22. issue 12. 2015-08-03. PMID:24378256. |
smaller hippocampal volumes are observed in depression but it remains unclear how antidepressant response and persistent depression relate to changes in hippocampal volume. |
2015-08-03 |
2023-08-12 |
Not clear |
| Warren D Taylor, Douglas R McQuoid, Martha E Payne, Anthony S Zannas, James R MacFall, David C Steffen. Hippocampus atrophy and the longitudinal course of late-life depression. The American journal of geriatric psychiatry : official journal of the American Association for Geriatric Psychiatry. vol 22. issue 12. 2015-08-03. PMID:24378256. |
we examined the longitudinal relationship between hippocampal atrophy and course of late-life depression. |
2015-08-03 |
2023-08-12 |
Not clear |
| Hui Qiao, Shu-Cheng An, Wei Ren, Xin-Ming M. Progressive alterations of hippocampal CA3-CA1 synapses in an animal model of depression. Behavioural brain research. vol 275. 2015-07-24. PMID:25192638. |
progressive alterations of hippocampal ca3-ca1 synapses in an animal model of depression. |
2015-07-24 |
2023-08-13 |
rat |
| Hui Qiao, Shu-Cheng An, Wei Ren, Xin-Ming M. Progressive alterations of hippocampal CA3-CA1 synapses in an animal model of depression. Behavioural brain research. vol 275. 2015-07-24. PMID:25192638. |
the aim of this study was to characterize the progressive alteration of neuronal plasticity in the male rat hippocampus during depression induced by chronic unpredictable mild stress (cums), an established animal model of depression. |
2015-07-24 |
2023-08-13 |
rat |
| Shreaya Chakroborty, Joyce Kim, Corinne Schneider, Anthony R West, Grace E Stutzman. Nitric oxide signaling is recruited as a compensatory mechanism for sustaining synaptic plasticity in Alzheimer's disease mice. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 35. issue 17. 2015-07-21. PMID:25926464. |
using a combination of electrophysiological approaches, two-photon calcium imaging, and protein biochemistry in hippocampal tissue from presymptomatic 3xtg-ad and nontg mice, we show that blocking no synthesis results in markedly augmented synaptic depression mediated through presynaptic mechanisms in 3xtg-ad mice. |
2015-07-21 |
2023-08-13 |
mouse |
| Jangama S M Smitha, Ravindranath Roopa, B K Chandrasekhar Sagar, Bindu M Kutty, Chittaranjan Andrad. Images in electroconvulsive therapy: ECS dose-dependently increases cell proliferation in the subgranular region of the rat hippocampus. The journal of ECT. vol 30. issue 3. 2015-07-20. PMID:24901429. |
stress and depression are associated with impaired neuroplasticity in the hippocampus; there is a decrease in neurogenesis, which is hypothesized to decrease the adaptative competence of the organism. |
2015-07-20 |
2023-08-13 |
rat |
| Jangama S M Smitha, Ravindranath Roopa, Nagarchi Khaleel, Bindu M Kutty, Chittaranjan Andrad. Images in electroconvulsive therapy: electroconvulsive shocks dose-dependently increase dendritic arborization in the CA1 region of the rat hippocampus. The journal of ECT. vol 30. issue 3. 2015-07-20. PMID:24901430. |
stress and depression are associated with impaired neuroplasticity in the hippocampus: there is decreased dendritic arborization and synaptogenesis, which is hypothesized to explain decreased adaptive competence of the organism. |
2015-07-20 |
2023-08-13 |
rat |
| Yan-Wei Luo, Yang Xu, Wen-Yu Cao, Xiao-Lin Zhong, Juan Duan, Xue-Qin Wang, Zhao-Lan Hu, Fang Li, Jian-Yi Zhang, Ming Zhou, Ru-Ping Dai, Chang-Qi L. Insulin-like growth factor 2 mitigates depressive behavior in a rat model of chronic stress. Neuropharmacology. vol 89. 2015-07-15. PMID:25446675. |
here, the role of igf2 expression in the hippocampus was investigated in a rat model of depression. |
2015-07-15 |
2023-08-13 |
rat |
| Nils Opel, Ronny Redlich, Peter Zwanzger, Dominik Grotegerd, Volker Arolt, Walter Heindel, Carsten Konrad, Harald Kugel, Udo Dannlowsk. Hippocampal atrophy in major depression: a function of childhood maltreatment rather than diagnosis? Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology. vol 39. issue 12. 2015-07-10. PMID:24924799. |
hippocampal atrophy in major depression: a function of childhood maltreatment rather than diagnosis? |
2015-07-10 |
2023-08-13 |
human |