| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Lin-Sheng Shi, Chun-Hui Ji, Wen-Qian Tang, Yue Liu, Wei Zhang, Wei Gua. Hippocampal miR-124 participates in the pathogenesis of depression via regulating the expression of BDNF in a Chronic Social Defeat Stress model of depression. Current neurovascular research. 2022-07-15. PMID:35838216. |
conclusion hippocampal mir-124 participated in the pathogenesis of depression by regulating bdnf biosynthesis and was a feasible antidepressant target. |
2022-07-15 |
2023-08-14 |
mouse |
| Lin Li, Yuting Zou, Baoe Liu, Runan Yang, Jingjian Yang, Minghao Sun, Zijing Li, Xiumei Xu, Guilin Li, Shuangmei Liu, Wolfgang Greffrath, Rolf-Detlef Treede, Guodong Li, Shangdong Lian. Correction to "Contribution of the P2X4 Receptor in Rat Hippocampus to the Comorbidity of Chronic Pain and Depression". ACS chemical neuroscience. 2022-07-15. PMID:35839517. |
correction to "contribution of the p2x4 receptor in rat hippocampus to the comorbidity of chronic pain and depression". |
2022-07-15 |
2023-08-14 |
rat |
| Evgeniya V Markova, Maria A Knyazheva, Maria A Tikhonova, Tamara G Amstislavskay. Structural and functional characteristics of the hippocampus in depressive-like recipients after transplantation of in vitro caffeine-modulated immune cells. Neuroscience letters. 2022-07-15. PMID:35839995. |
the hippocampus is a key anatomical brain region associated with depression. |
2022-07-15 |
2023-08-14 |
mouse |
| Riley A Williams, Kenneth W Johnson, Francis S Lee, Hugh C Hemmings, Jimcy Plathol. A Common Human Brain-Derived Neurotrophic Factor Polymorphism Leads to Prolonged Depression of Excitatory Synaptic Transmission by Isoflurane in Hippocampal Cultures. Frontiers in molecular neuroscience. vol 15. 2022-07-11. PMID:35813074. |
a common human brain-derived neurotrophic factor polymorphism leads to prolonged depression of excitatory synaptic transmission by isoflurane in hippocampal cultures. |
2022-07-11 |
2023-08-14 |
mouse |
| Guangping Qin, Zhuo L. Effects of miR-124-3p Silencing on Neuronal Damage in the Hippocampus of Depression Rats by Regulating STAT3 Gene. Computational and mathematical methods in medicine. vol 2022. 2022-07-11. PMID:35813421. |
effects of mir-124-3p silencing on neuronal damage in the hippocampus of depression rats by regulating stat3 gene. |
2022-07-11 |
2023-08-14 |
rat |
| Guangping Qin, Zhuo L. Effects of miR-124-3p Silencing on Neuronal Damage in the Hippocampus of Depression Rats by Regulating STAT3 Gene. Computational and mathematical methods in medicine. vol 2022. 2022-07-11. PMID:35813421. |
therefore, we investigated the effect of mir-124-3p on neuronal damage in the hippocampus of depression rats. |
2022-07-11 |
2023-08-14 |
rat |
| Iris Álvarez-Merz, Ioulia V Fomitcheva, Jeremy Sword, Jesús M Hernández-Guijo, José M Solís, Sergei A Kiro. Novel mechanism of hypoxic neuronal injury mediated by non-excitatory amino acids and astroglial swelling. Glia. 2022-07-08. PMID:35802030. |
hypoxia-induced synaptic depression in hippocampal slices becomes irreversible with non-excitatory aa, alongside their intracellular accumulation and increased tissue electrical resistance. |
2022-07-08 |
2023-08-14 |
mouse |
| Andrea Du Preez, Sophie Lefèvre-Arbogast, Raúl González-Domínguez, Vikki Houghton, Chiara de Lucia, Dorrain Y Low, Catherine Helmer, Catherine Féart, Cécile Delcourt, Cécile Proust-Lima, Mercè Pallàs, Alex Sánchez-Pla, Mireia Urpi-Sardà, Silvie R Ruigrok, Barbara Altendorfer, Ludwig Aigner, Paul J Lucassen, Aniko Korosi, Claudine Manach, Cristina Andres-Lacueva, Cécilia Samieri, Sandrine Thure. Impaired hippocampal neurogenesis in vitro is modulated by dietary-related endogenous factors and associated with depression in a longitudinal ageing cohort study. Molecular psychiatry. 2022-07-06. PMID:35794184. |
impaired hippocampal neurogenesis in vitro is modulated by dietary-related endogenous factors and associated with depression in a longitudinal ageing cohort study. |
2022-07-06 |
2023-08-14 |
human |
| Andrea Du Preez, Sophie Lefèvre-Arbogast, Raúl González-Domínguez, Vikki Houghton, Chiara de Lucia, Dorrain Y Low, Catherine Helmer, Catherine Féart, Cécile Delcourt, Cécile Proust-Lima, Mercè Pallàs, Alex Sánchez-Pla, Mireia Urpi-Sardà, Silvie R Ruigrok, Barbara Altendorfer, Ludwig Aigner, Paul J Lucassen, Aniko Korosi, Claudine Manach, Cristina Andres-Lacueva, Cécilia Samieri, Sandrine Thure. Impaired hippocampal neurogenesis in vitro is modulated by dietary-related endogenous factors and associated with depression in a longitudinal ageing cohort study. Molecular psychiatry. 2022-07-06. PMID:35794184. |
this could be partially driven by the food metabolome, which communicates with the brain via the circulatory system and interacts with hippocampal neurogenesis (hn), a form of brain plasticity implicated in depression aetiology. |
2022-07-06 |
2023-08-14 |
human |
| Nora Schaub, Nina Ammann, Frauke Conring, Thomas Müller, Andrea Federspiel, Roland Wiest, Robert Hoepner, Katharina Stegmayer, Sebastian Walthe. Effect of Season of Birth on Hippocampus Volume in a Transdiagnostic Sample of Patients With Depression and Schizophrenia. Frontiers in human neuroscience. vol 16. 2022-06-30. PMID:35769255. |
effect of season of birth on hippocampus volume in a transdiagnostic sample of patients with depression and schizophrenia. |
2022-06-30 |
2023-08-14 |
Not clear |
| Jing Li, Peilin Zhu, Yue Li, Kai Xiao, Jing Tang, Xin Liang, Yanmin Luo, Jin Wang, Yuhui Deng, Lin Jiang, Qian Xiao, Yijing Guo, Yong Tang, Chunxia Huan. The liver X receptors agonist GW3965 attenuates depressive-like behaviors and suppresses microglial activation and neuroinflammation in hippocampal subregions in a mouse depression model. The Journal of comparative neurology. 2022-06-27. PMID:35758275. |
the liver x receptors agonist gw3965 attenuates depressive-like behaviors and suppresses microglial activation and neuroinflammation in hippocampal subregions in a mouse depression model. |
2022-06-27 |
2023-08-14 |
mouse |
| Jing Li, Peilin Zhu, Yue Li, Kai Xiao, Jing Tang, Xin Liang, Yanmin Luo, Jin Wang, Yuhui Deng, Lin Jiang, Qian Xiao, Yijing Guo, Yong Tang, Chunxia Huan. The liver X receptors agonist GW3965 attenuates depressive-like behaviors and suppresses microglial activation and neuroinflammation in hippocampal subregions in a mouse depression model. The Journal of comparative neurology. 2022-06-27. PMID:35758275. |
hippocampal neuroinflammation and impairment of the normal structure and function of microglia are closely associated with depression. |
2022-06-27 |
2023-08-14 |
mouse |
| Mi Kyoung Seo, Jung An Lee, Sehoon Jeong, Dae-Hyun Seog, Jung Goo Lee, Sung Woo Par. Effects of Chronic LY341495 on Hippocampal mTORC1 Signaling in Mice with Chronic Unpredictable Stress-Induced Depression. International journal of molecular sciences. vol 23. issue 12. 2022-06-24. PMID:35742857. |
effects of chronic ly341495 on hippocampal mtorc1 signaling in mice with chronic unpredictable stress-induced depression. |
2022-06-24 |
2023-08-14 |
mouse |
| Mi Kyoung Seo, Jung An Lee, Sehoon Jeong, Dae-Hyun Seog, Jung Goo Lee, Sung Woo Par. Effects of Chronic LY341495 on Hippocampal mTORC1 Signaling in Mice with Chronic Unpredictable Stress-Induced Depression. International journal of molecular sciences. vol 23. issue 12. 2022-06-24. PMID:35742857. |
our results suggest that the activation of hippocampal mtorc1 signaling is related to the antidepressant effect of chronic ly341495 treatment in an animal model of cus-induced depression. |
2022-06-24 |
2023-08-14 |
mouse |
| Teng Wan, Xiaoyu Li, Mingyuan Fu, Xiaoyu Gao, Peiling Li, Weiming Gu. NLRP3-Dependent Pyroptosis: A Candidate Therapeutic Target for Depression. Frontiers in cellular neuroscience. vol 16. 2022-06-20. PMID:35722622. |
studies have shown that depression is closely associated with pyroptosis and the induced neuroinflammation of relevant brain regions, such as the hippocampus, amygdala, prefrontal cortex neurons, etc., in which the nucleotide-binding oligomerization domain-like receptor protein 3 inflammasome plays a crucial role. |
2022-06-20 |
2023-08-14 |
Not clear |
| Zhenyao Lu, Sijia Li, Nan Aa, Yuanmao Zhang, Ran Zhang, Chen Xu, Shize Zhang, Xiangqing Kong, Guangji Wang, Jiye Aa, Yue Zhan. Quantitative analysis of 20 purine and pyrimidine metabolites by HILIC-MS/MS in the serum and hippocampus of depressed mice. Journal of pharmaceutical and biomedical analysis. 2022-06-17. PMID:35715372. |
an analytical strategy was successfully applied to quantitatively determine 20 metabolite levels in the serum and hippocampus of mice with chronic social defeat stress-induced depression. |
2022-06-17 |
2023-08-14 |
mouse |
| Shanshan Zhang, Juntao Hu, Guixue Liu, Haoran Wu, Meihui Li, Chenye Shi, Qiong Liu, Wensheng L. Chronic clomipramine treatment increases hippocampal volume in rats exposed to chronic unpredictable mild stress. Translational psychiatry. vol 12. issue 1. 2022-06-10. PMID:35688836. |
due to individual differences in clinical research, the reduction of hippocampal volume in patients with depression is still controversial. |
2022-06-10 |
2023-08-14 |
rat |
| Hikaru Takeuchi, Yuka Shiota, Ken Yaoi, Yasuyuki Taki, Rui Nouchi, Ryoichi Yokoyama, Yuka Kotozaki, Seishu Nakagawa, Atsushi Sekiguchi, Kunio Iizuka, Sugiko Hanawa, Tsuyoshi Araki, Carlos Makoto Miyauchi, Kohei Sakaki, Takayuki Nozawa, Shigeyuki Ikeda, Susumu Yokota, Daniele Magistro, Yuko Sassa, Ryuta Kawashim. Mercury levels in hair are associated with reduced neurobehavioral performance and altered brain structures in young adults. Communications biology. vol 5. issue 1. 2022-06-02. PMID:35655003. |
here, utilizing hair analysis which has been advocated as a method for biological monitoring, data of regional gray matter volume (rgmv), regional white matter volume (rwmv), fractional anisotropy (fa) and mean diffusivity (md), cognitive functions, and depression among 920 healthy young adults in japan, we showed that greater hair mercury levels were weakly but significantly associated with diminished cognitive performance, particularly on tasks requiring rapid processing (speed measures), lower depressive tendency, lower rgmv in areas of the thalamus and hippocampus, lower rwmv in widespread areas, greater fa in bilaterally distributed white matter areas overlapping with areas of significant rwmv reductions and lower md of the widely distributed gray and white matter areas particularly in the bilateral frontal lobe and the right basal ganglia. |
2022-06-02 |
2023-08-14 |
Not clear |
| Ilia G Komoltsev, Natalia V Gulyaev. Brain Trauma, Glucocorticoids and Neuroinflammation: Dangerous Liaisons for the Hippocampus. Biomedicines. vol 10. issue 5. 2022-05-28. PMID:35625876. |
glucocorticoid-mediated long-lasting neuronal circuit changes in the hippocampus after brain trauma are involved in late post-traumatic pathology development, such as epilepsy, depression and cognitive impairment. |
2022-05-28 |
2023-08-13 |
Not clear |
| Bradley S Peterson, Tejal Kaur, Maria Andrea Baez, Ronald C Whiteman, Siddhant Sawardekar, Juan Sanchez-Peña, Xuejun Hao, Kristin W Klahr, Ardesheer Talati, Priya Wickramaratne, Myrna M Weissman, Ravi Bansa. Morphological Biomarkers in the Amygdala and Hippocampus of Children and Adults at High Familial Risk for Depression. Diagnostics (Basel, Switzerland). vol 12. issue 5. 2022-05-28. PMID:35626374. |
morphological biomarkers in the amygdala and hippocampus of children and adults at high familial risk for depression. |
2022-05-28 |
2023-08-13 |
human |