All Relations between Depression and hippocampus
| Publication | Sentence | Publish Date | Extraction Date | Species |
|---|---|---|---|---|
| Galina T Shishkina, Tatyana S Kalinina, Inna V Berezova, Nikolay N Dygal. Stress-induced activation of the brainstem Bcl-xL gene expression in rats treated with fluoxetine: correlations with serotonin metabolism and depressive-like behavior. Neuropharmacology. vol 62. issue 1. 2012-08-13. PMID:21740920. | mechanisms underlying stress-induced depression and antidepressant drug action were shown to involve alterations in serotonergic (5-ht) neurotransmission and expression of genes coding for proteins associated with neurotrophic signaling pathways and cell-survival in the hippocampus and cortex. | 2012-08-13 | 2023-08-12 | rat |
| Q Wang, M Joels, D F Swaab, P J Lucasse. Hippocampal GR expression is increased in elderly depressed females. Neuropharmacology. vol 62. issue 1. 2012-08-13. PMID:21945289. | whether this sex difference in hippocampal gr-ir in depression relates to the increased incidence of depression in females awaits further study. | 2012-08-13 | 2023-08-12 | human |
| Philippe A Melas, Mattias Mannervik, Aleksander A Mathé, Catharina Lavebrat. Neuropeptide Y: identification of a novel rat mRNA splice-variant that is downregulated in the hippocampus and the prefrontal cortex of a depression-like model. Peptides. vol 35. issue 1. 2012-08-07. PMID:22406386. | since the hippocampus and the prefrontal cortex play an important role in affective disorders, we investigated alternative splicing of npy in these regions of a rat model of depression (flinders sensitive line, fsl) and its controls (flinders resistant line, frl). | 2012-08-07 | 2023-08-12 | rat |
| Kathryn M Gill, Anthony A Grac. Heterogeneous processing of amygdala and hippocampal inputs in the rostral and caudal subregions of the nucleus accumbens. The international journal of neuropsychopharmacology. vol 14. issue 10. 2012-07-30. PMID:21211108. | in addition, the hippocampus inappropriately dominates information processing within this circuit, potentially contributing to the overwhelming focus on internal emotional states in disorders such as depression. | 2012-07-30 | 2023-08-12 | rat |
| Majid Fotuhi, David Do, Clifford Jac. Modifiable factors that alter the size of the hippocampus with ageing. Nature reviews. Neurology. vol 8. issue 4. 2012-07-30. PMID:22410582. | the hippocampus is particularly vulnerable to the neurotoxic effects of obesity, diabetes mellitus, hypertension, hypoxic brain injury, obstructive sleep apnoea, bipolar disorder, clinical depression and head trauma. | 2012-07-30 | 2023-08-12 | Not clear |
| Pontus Wasling, Joakim Strandberg, Eric Hans. AMPA receptor activation causes silencing of AMPA receptor-mediated synaptic transmission in the developing hippocampus. PloS one. vol 7. issue 4. 2012-07-27. PMID:22485173. | here we show that the agonist ampa causes a depression of ampa receptor (ampar) signaling at glutamate synapses in the ca1 region of the hippocampus in slices from developing, but not from mature, rats. | 2012-07-27 | 2023-08-12 | rat |
| Veronika Husarova, Michal Bittsansky, Igor Ondrejka, Valeria Kerna, Dusan Dobrot. Hippocampal neurometabolite changes in depression treatment: a (1)H magnetic resonance spectroscopy study. Psychiatry research. vol 201. issue 3. 2012-07-24. PMID:22507761. | hippocampal neurometabolite changes in depression treatment: a (1)h magnetic resonance spectroscopy study. | 2012-07-24 | 2023-08-12 | Not clear |
| Veronika Husarova, Michal Bittsansky, Igor Ondrejka, Valeria Kerna, Dusan Dobrot. Hippocampal neurometabolite changes in depression treatment: a (1)H magnetic resonance spectroscopy study. Psychiatry research. vol 201. issue 3. 2012-07-24. PMID:22507761. | previous studies using magnetic resonance spectroscopy have related abnormalities in hippocampal metabolism to depression. | 2012-07-24 | 2023-08-12 | Not clear |
| Veronika Husarova, Michal Bittsansky, Igor Ondrejka, Valeria Kerna, Dusan Dobrot. Hippocampal neurometabolite changes in depression treatment: a (1)H magnetic resonance spectroscopy study. Psychiatry research. vol 201. issue 3. 2012-07-24. PMID:22507761. | eighteen adult patients with major depressive disorder, aged 20 to 60 years, underwent magnetic resonance spectroscopy of the hippocampus during a period of depressive symptomatology and after 7-11 weeks of antidepressant medication with at least 50% reduction in the montgomery-Åsberg depression rating scale ()madrs score. | 2012-07-24 | 2023-08-12 | Not clear |
| Neil M Fournier, Ronald S Duma. Role of vascular endothelial growth factor in adult hippocampal neurogenesis: implications for the pathophysiology and treatment of depression. Behavioural brain research. vol 227. issue 2. 2012-07-19. PMID:21536078. | role of vascular endothelial growth factor in adult hippocampal neurogenesis: implications for the pathophysiology and treatment of depression. | 2012-07-19 | 2023-08-12 | Not clear |
| Yukitoshi Izumi, Charles F Zorumsk. NMDA receptors, mGluR5, and endocannabinoids are involved in a cascade leading to hippocampal long-term depression. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology. vol 37. issue 3. 2012-07-19. PMID:21993209. | in the ca1 region of the rat hippocampus, metabotropic glutamate receptor-5 (mglur5) and cannabinoid-1 receptors (cb1rs) are believed to participate in long-term synaptic depression (ltd). | 2012-07-19 | 2023-08-12 | rat |
| Nicole Carrier, Mohamed Kabba. Extracellular signal-regulated kinase 2 signaling in the hippocampal dentate gyrus mediates the antidepressant effects of testosterone. Biological psychiatry. vol 71. issue 7. 2012-07-17. PMID:22265242. | in this study, we sought to investigate the molecular mechanisms underlying the antidepressant effects of testosterone within the hippocampus, an area that is fundamental in the etiology of depression. | 2012-07-17 | 2023-08-12 | human |
| Isabella Peruga, Silvia Hartwig, Doron Merkler, Jan Thöne, Bernhard Hovemann, Georg Juckel, Ralf Gold, Ralf A Linke. Endogenous ciliary neurotrophic factor modulates anxiety and depressive-like behavior. Behavioural brain research. vol 229. issue 2. 2012-07-17. PMID:22266927. | these data imply that endogenous cntf plays a pivotal role for the structural maintenance of hippocampal functions and thus has an important impact on the modulation of affective behavior in rodent models of anxiety and depression. | 2012-07-17 | 2023-08-12 | mouse |
| Jia Liang, Jun Lu, Shan-Fu Cui, Jun-Ren Wang, Ya T. [Effect of acupuncture on expression of brain-derived neurotrophic factor gene and protein in frontal cortex and hippocampus of depression rats]. Zhen ci yan jiu = Acupuncture research. vol 37. issue 1. 2012-07-17. PMID:22574564. | [effect of acupuncture on expression of brain-derived neurotrophic factor gene and protein in frontal cortex and hippocampus of depression rats]. | 2012-07-17 | 2023-08-12 | rat |
| Jia Liang, Jun Lu, Shan-Fu Cui, Jun-Ren Wang, Ya T. [Effect of acupuncture on expression of brain-derived neurotrophic factor gene and protein in frontal cortex and hippocampus of depression rats]. Zhen ci yan jiu = Acupuncture research. vol 37. issue 1. 2012-07-17. PMID:22574564. | to observe the influence of acupuncture of "baihui" (gv 20) to "yintang" (ex-hn 3) and unilateral "neiguan" (pc 6) on the expression of brain-derived neurotrophic factor (bdnf) gene and protein in the prefrontal cortex and hippocampus in chronic stress-induced depression rats. | 2012-07-17 | 2023-08-12 | rat |
| Holly F Green, Eimear Treacy, Aoife K Keohane, Aideen M Sullivan, Gerard W O'Keeffe, Yvonne M Nola. A role for interleukin-1β in determining the lineage fate of embryonic rat hippocampal neural precursor cells. Molecular and cellular neurosciences. vol 49. issue 3. 2012-07-13. PMID:22270046. | prolonged release of interleukin-1β (il-1β) from activated microglia has a deleterious effect on hippocampal neurons and is implicated in the impaired neurogenesis and cognitive dysfunction associated with aging, alzheimer's disease and depression. | 2012-07-13 | 2023-08-12 | rat |
| D Arnone, A M McIntosh, K P Ebmeier, M R Munafò, I M Anderso. Magnetic resonance imaging studies in unipolar depression: systematic review and meta-regression analyses. European neuropsychopharmacology : the journal of the European College of Neuropsychopharmacology. vol 22. issue 1. 2012-07-11. PMID:21723712. | unipolar depression was characterised by reduced brain volume in areas involved in emotional processing, including the frontal cortex, orbitofrontal cortex, cingulate cortex, hippocampus and striatum. | 2012-07-11 | 2023-08-12 | human |
| Jason L Stein, Sarah E Medland, Alejandro Arias Vasquez, Derrek P Hibar, Rudy E Senstad, Anderson M Winkler, Roberto Toro, Katja Appel, Richard Bartecek, Ørjan Bergmann, Manon Bernard, Andrew A Brown, Dara M Cannon, M Mallar Chakravarty, Andrea Christoforou, Martin Domin, Oliver Grimm, Marisa Hollinshead, Avram J Holmes, Georg Homuth, Jouke-Jan Hottenga, Camilla Langan, Lorna M Lopez, Narelle K Hansell, Kristy S Hwang, Sungeun Kim, Gonzalo Laje, Phil H Lee, Xinmin Liu, Eva Loth, Anbarasu Lourdusamy, Morten Mattingsdal, Sebastian Mohnke, Susana Muñoz Maniega, Kwangsik Nho, Allison C Nugent, Carol O'Brien, Martina Papmeyer, Benno Pütz, Adaikalavan Ramasamy, Jerod Rasmussen, Mark Rijpkema, Shannon L Risacher, J Cooper Roddey, Emma J Rose, Mina Ryten, Li Shen, Emma Sprooten, Eric Strengman, Alexander Teumer, Daniah Trabzuni, Jessica Turner, Kristel van Eijk, Theo G M van Erp, Marie-Jose van Tol, Katharina Wittfeld, Christiane Wolf, Saskia Woudstra, Andre Aleman, Saud Alhusaini, Laura Almasy, Elisabeth B Binder, David G Brohawn, Rita M Cantor, Melanie A Carless, Aiden Corvin, Michael Czisch, Joanne E Curran, Gail Davies, Marcio A A de Almeida, Norman Delanty, Chantal Depondt, Ravi Duggirala, Thomas D Dyer, Susanne Erk, Jesen Fagerness, Peter T Fox, Nelson B Freimer, Michael Gill, Harald H H Göring, Donald J Hagler, David Hoehn, Florian Holsboer, Martine Hoogman, Norbert Hosten, Neda Jahanshad, Matthew P Johnson, Dalia Kasperaviciute, Jack W Kent, Peter Kochunov, Jack L Lancaster, Stephen M Lawrie, David C Liewald, René Mandl, Mar Matarin, Manuel Mattheisen, Eva Meisenzahl, Ingrid Melle, Eric K Moses, Thomas W Mühleisen, Matthias Nauck, Markus M Nöthen, Rene L Olvera, Massimo Pandolfo, G Bruce Pike, Ralf Puls, Ivar Reinvang, Miguel E Rentería, Marcella Rietschel, Joshua L Roffman, Natalie A Royle, Dan Rujescu, Jonathan Savitz, Hugo G Schnack, Knut Schnell, Nina Seiferth, Colin Smith, Vidar M Steen, Maria C Valdés Hernández, Martijn Van den Heuvel, Nic J van der Wee, Neeltje E M Van Haren, Joris A Veltman, Henry Völzke, Robert Walker, Lars T Westlye, Christopher D Whelan, Ingrid Agartz, Dorret I Boomsma, Gianpiero L Cavalleri, Anders M Dale, Srdjan Djurovic, Wayne C Drevets, Peter Hagoort, Jeremy Hall, Andreas Heinz, Clifford R Jack, Tatiana M Foroud, Stephanie Le Hellard, Fabio Macciardi, Grant W Montgomery, Jean Baptiste Poline, David J Porteous, Sanjay M Sisodiya, John M Starr, Jessika Sussmann, Arthur W Toga, Dick J Veltman, Henrik Walter, Michael W Weiner, Joshua C Bis, M Arfan Ikram, Albert V Smith, Vilmundur Gudnason, Christophe Tzourio, Meike W Vernooij, Lenore J Launer, Charles DeCarli, Sudha Seshadri, Ole A Andreassen, Liana G Apostolova, Mark E Bastin, John Blangero, Han G Brunner, Randy L Buckner, Sven Cichon, Giovanni Coppola, Greig I de Zubicaray, Ian J Deary, Gary Donohoe, Eco J C de Geus, Thomas Espeseth, Guillén Fernández, David C Glahn, Hans J Grabe, John Hardy, Hilleke E Hulshoff Pol, Mark Jenkinson, René S Kahn, Colm McDonald, Andrew M McIntosh, Francis J McMahon, Katie L McMahon, Andreas Meyer-Lindenberg, Derek W Morris, Bertram Müller-Myhsok, Thomas E Nichols, Roel A Ophoff, Tomas Paus, Zdenka Pausova, Brenda W Penninx, Steven G Potkin, Philipp G Sämann, Andrew J Saykin, Gunter Schumann, Jordan W Smoller, Joanna M Wardlaw, Michael E Weale, Nicholas G Martin, Barbara Franke, Margaret J Wright, Paul M Thompso. Identification of common variants associated with human hippocampal and intracranial volumes. Nature genetics. vol 44. issue 5. 2012-07-02. PMID:22504417. | the volume of the hippocampus is a biomarker of incipient alzheimer's disease and is reduced in schizophrenia, major depression and mesial temporal lobe epilepsy. | 2012-07-02 | 2023-08-12 | human |
| Shao-Feng Li, Mei-Na Wu, Xiao-Hui Wang, Li Yuan, Dong Yang, Jin-Shun Q. Requirement of α7 nicotinic acetylcholine receptors for amyloid β protein-induced depression of hippocampal long-term potentiation in CA1 region of rats in vivo. Synapse (New York, N.Y.). vol 65. issue 11. 2012-06-18. PMID:21584864. | requirement of α7 nicotinic acetylcholine receptors for amyloid β protein-induced depression of hippocampal long-term potentiation in ca1 region of rats in vivo. | 2012-06-18 | 2023-08-12 | rat |
| Shao-Feng Li, Mei-Na Wu, Xiao-Hui Wang, Li Yuan, Dong Yang, Jin-Shun Q. Requirement of α7 nicotinic acetylcholine receptors for amyloid β protein-induced depression of hippocampal long-term potentiation in CA1 region of rats in vivo. Synapse (New York, N.Y.). vol 65. issue 11. 2012-06-18. PMID:21584864. | the results show that: (1) intracerebroventicular injection of aβ25-35 or aβ31-35 significantly and similarly suppressed hippocampal ltp in ca1 region in rats; (2) choline, a selective α7 nachr agonist, did not affect the ltp induction but enhanced ltp suppression induced by aβ31-35; and (3) methyllycaconitine, a specific α7 nachr antagonist, slightly suppressed hippocamal ltp but effectively prevented against aβ31-35-induced ltp depression in the presence of aβ31-35. | 2012-06-18 | 2023-08-12 | rat |