| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Siu W Tang, Daiga Helmeste, Brian Leonar. Is neurogenesis relevant in depression and in the mechanism of antidepressant drug action? A critical review. The world journal of biological psychiatry : the official journal of the World Federation of Societies of Biological Psychiatry. vol 13. issue 6. 2013-01-07. PMID:22175526. |
however, careful examination of the literature suggests that the complex biological and psychological changes associated with depression cannot be attributed to disturbance in hippocampal neurogenesis alone. |
2013-01-07 |
2023-08-12 |
Not clear |
| Jelena Djordjevic, Ana Djordjevic, Miroslav Adzic, Marija B Radojci. Effects of chronic social isolation on Wistar rat behavior and brain plasticity markers. Neuropsychobiology. vol 66. issue 2. 2013-01-07. PMID:22814229. |
previously, we investigated the effects of chronic social stress in the limbic brain structures of wistar rats (hippocampus, hippo, and prefrontal cortex, pfc) and found multiple characteristics that resembled alterations described in some clinical studies of depression. |
2013-01-07 |
2023-08-12 |
rat |
| Paul Smolen, Douglas A Baxter, John H Byrn. Molecular constraints on synaptic tagging and maintenance of long-term potentiation: a predictive model. PLoS computational biology. vol 8. issue 8. 2012-12-14. PMID:22876169. |
protein synthesis-dependent, late long-term potentiation (ltp) and depression (ltd) at glutamatergic hippocampal synapses are well characterized examples of long-term synaptic plasticity. |
2012-12-14 |
2023-08-12 |
Not clear |
| Juan Gibert Rahol. Somatic drugs for psychiatric diseases: aspirin or simvastatin for depression? Current neuropharmacology. vol 10. issue 2. 2012-12-12. PMID:23204984. |
although scientists are still a long way from understanding its true aetiology, the neurobiological concept of depression has evolved from receptor regulation disorder, to a neurodegenerative disorder with a hippocampal volume decrease with the controversial reduction in neurotrophins such as bdnf, to current hypotheses that consider depression to be an inflammatory and neuroprogressive process. |
2012-12-12 |
2023-08-12 |
Not clear |
| Xiao-hong Li, Jing-jing Li, Yue-yun Liu, Jia-xu Che. [Central neurobiological mechanism of liver depression and spleen deficiency syndrome based on chronic stress: a review]. Zhong xi yi jie he xue bao = Journal of Chinese integrative medicine. vol 10. issue 1. 2012-12-06. PMID:22237267. |
the research showed that the central neurobiology mechanism of liver depression and spleen deficiency syndrome closely correlates to the hypothalamic-pituitary-adrenal axis, brain-gut axis, myriad central neurotrophic factors, neurotransmitters, neuropeptides and hormones and their receptors, involving in many encephalic regions such as the hypothalamus, hippocampus, cortex, amygdale, etc. |
2012-12-06 |
2023-08-12 |
rat |
| Rui Liu, Wei Dang, Miao Jianting, Changjun Su, Huaning Wang, Yunchun Chen, Qingrong Ta. Citalopram alleviates chronic stress induced depression-like behaviors in rats by activating GSK3β signaling in dorsal hippocampus. Brain research. vol 1467. 2012-11-20. PMID:22634067. |
these findings suggest that the wnt-dvl-gsk3β signaling in the hippocampus is markedly involved in the pathophysiology of depression induced by chronic stress. |
2012-11-20 |
2023-08-12 |
rat |
| Daphne Everaerd, Lotte Gerritsen, Mark Rijpkema, Thomas Frodl, Iris van Oostrom, Barbara Franke, Guillén Fernández, Indira Tendolka. Sex modulates the interactive effect of the serotonin transporter gene polymorphism and childhood adversity on hippocampal volume. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology. vol 37. issue 8. 2012-11-13. PMID:22434222. |
moreover, sex, which is known to affect the prevalence of depression substantially, has not been taken into account when trying to disentangle the interactive effect of common genetic variation and environmental stressors on the hippocampus. |
2012-11-13 |
2023-08-12 |
Not clear |
| K A Baranova, E A Rybnikova, M O Samoilo. Antidepressant effect of hypoxic preconditioning is associated with modification of expression of transcription factor c-Fos in rat brain in response to unavoidable stress. Bulletin of experimental biology and medicine. vol 152. issue 5. 2012-11-13. PMID:22803133. |
development of post-stress depression in rats was accompanied by long-term moderate activation of the expression of transcription factor c-fos in the neocortex, hippocampus, and paraventricular nucleus of the hypothalamus. |
2012-11-13 |
2023-08-12 |
rat |
| Susanne S Kaae, Fenghua Chen, Gregers Wegener, Torsten M Madsen, Jens R Nyengaar. Quantitative hippocampal structural changes following electroconvulsive seizure treatment in a rat model of depression. Synapse (New York, N.Y.). vol 66. issue 8. 2012-11-09. PMID:22389166. |
quantitative hippocampal structural changes following electroconvulsive seizure treatment in a rat model of depression. |
2012-11-09 |
2023-08-12 |
rat |
| Susanne S Kaae, Fenghua Chen, Gregers Wegener, Torsten M Madsen, Jens R Nyengaar. Quantitative hippocampal structural changes following electroconvulsive seizure treatment in a rat model of depression. Synapse (New York, N.Y.). vol 66. issue 8. 2012-11-09. PMID:22389166. |
the pathophysiology of depression and the effects of antidepressant treatment are hypothesized to be related to hippocampal structural changes. |
2012-11-09 |
2023-08-12 |
rat |
| Susanne S Kaae, Fenghua Chen, Gregers Wegener, Torsten M Madsen, Jens R Nyengaar. Quantitative hippocampal structural changes following electroconvulsive seizure treatment in a rat model of depression. Synapse (New York, N.Y.). vol 66. issue 8. 2012-11-09. PMID:22389166. |
this study aims to investigate the effect of electroconvulsive seizures on behavior and hippocampal structure in a rat model of depression. |
2012-11-09 |
2023-08-12 |
rat |
| Gisele Pereira Dias, Nicole Cavegn, Alina Nix, Mário Cesar do Nascimento Bevilaqua, Doris Stangl, Muhammad Syahrul Anwar Zainuddin, Antonio Egidio Nardi, Patricia Franca Gardino, Sandrine Thure. The role of dietary polyphenols on adult hippocampal neurogenesis: molecular mechanisms and behavioural effects on depression and anxiety. Oxidative medicine and cellular longevity. vol 2012. 2012-11-06. PMID:22829957. |
the role of dietary polyphenols on adult hippocampal neurogenesis: molecular mechanisms and behavioural effects on depression and anxiety. |
2012-11-06 |
2023-08-12 |
Not clear |
| Gisele Pereira Dias, Nicole Cavegn, Alina Nix, Mário Cesar do Nascimento Bevilaqua, Doris Stangl, Muhammad Syahrul Anwar Zainuddin, Antonio Egidio Nardi, Patricia Franca Gardino, Sandrine Thure. The role of dietary polyphenols on adult hippocampal neurogenesis: molecular mechanisms and behavioural effects on depression and anxiety. Oxidative medicine and cellular longevity. vol 2012. 2012-11-06. PMID:22829957. |
in this paper, we discuss some recent findings addressing the effects of different dietary polyphenols on hippocampal cell proliferation and differentiation, models of anxiety, and depression as well as some proposed molecular mechanisms underlying those effects with particular focus on those related to ahn. |
2012-11-06 |
2023-08-12 |
Not clear |
| Kim Henningsen, Johan Palmfeldt, Sofie Christiansen, Isabel Baiges, Steffen Bak, Ole Nørregaard Jensen, Niels Gregersen, Ove Wibor. Candidate hippocampal biomarkers of susceptibility and resilience to stress in a rat model of depression. Molecular & cellular proteomics : MCP. vol 11. issue 7. 2012-10-30. PMID:22311638. |
candidate hippocampal biomarkers of susceptibility and resilience to stress in a rat model of depression. |
2012-10-30 |
2023-08-12 |
rat |
| Atsushi Taked. Zinc signaling in the hippocampus and its relation to pathogenesis of depression. Journal of trace elements in medicine and biology : organ of the Society for Minerals and Trace Elements (GMS). vol 26. issue 2-3. 2012-10-18. PMID:22560194. |
zinc signaling in the hippocampus and its relation to pathogenesis of depression. |
2012-10-18 |
2023-08-12 |
rat |
| Maureen M Blac. Integrated strategies needed to prevent iron deficiency and to promote early child development. Journal of trace elements in medicine and biology : organ of the Society for Minerals and Trace Elements (GMS). vol 26. issue 2-3. 2012-10-18. PMID:22664336. |
mechanisms linking iron deficiency to children's development may include alterations to dopamine metabolism, myelination, and hippocampal structure and function, as well as maternal depression and unresponsive caregiving, potentially associated with maternal id. |
2012-10-18 |
2023-08-12 |
Not clear |
| Nikolay N Dygalo, Tatyana S Kalinina, Veta V Bulygina, Galina T Shishkin. Increased expression of the anti-apoptotic protein Bcl-xL in the brain is associated with resilience to stress-induced depression-like behavior. Cellular and molecular neurobiology. vol 32. issue 5. 2012-10-17. PMID:22278304. |
the ability to increase bcl-xl gene expression in the hippocampus in response to stress may be an important factor for determining the resistance to the development of stress-induced depression. |
2012-10-17 |
2023-08-12 |
rat |
| Y Tizabi, B H Bhatti, K F Manaye, J R Das, L Akinfiresoy. Antidepressant-like effects of low ketamine dose is associated with increased hippocampal AMPA/NMDA receptor density ratio in female Wistar-Kyoto rats. Neuroscience. vol 213. 2012-10-16. PMID:22521815. |
here, we sought to determine whether ketamine would exert antidepressant effects in wistar-kyoto (wky) rats, a putative animal model of depression and whether this effect would be associated with changes in ampa/nmda receptor densities in the hippocampus. |
2012-10-16 |
2023-08-12 |
rat |
| Yu Pei, Alicia K Smith, Yongjun Wang, Yanli Pan, Jian Yang, Qi Chen, Weigang Pan, Feng Bao, Lisha Zhao, Changle Tie, Yizheng Wang, Jian Wang, Wenfeng Zhen, Jinxia Zhou, Xin M. The brain-derived neurotrophic-factor (BDNF) val66met polymorphism is associated with geriatric depression: a meta-analysis. American journal of medical genetics. Part B, Neuropsychiatric genetics : the official publication of the International Society of Psychiatric Genetics. vol 159B. issue 5. 2012-10-11. PMID:22610920. |
depression has been associated with reduced expression of brain-derived neurotrophic factor (bdnf) in the hippocampus. |
2012-10-11 |
2023-08-12 |
Not clear |
| Ronald S Duman, George K Aghajania. Synaptic dysfunction in depression: potential therapeutic targets. Science (New York, N.Y.). vol 338. issue 6103. 2012-10-11. PMID:23042884. |
basic and clinical studies demonstrate that depression is associated with reduced size of brain regions that regulate mood and cognition, including the prefrontal cortex and the hippocampus, and decreased neuronal synapses in these areas. |
2012-10-11 |
2023-08-12 |
Not clear |