| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| S Kasper, G Voll, A Vieira, H Kic. Response to total sleep deprivation before and during treatment with fluvoxamine or maprotiline in patients with major depression--results of a double-blind study. Pharmacopsychiatry. vol 23. issue 3. 1990-08-29. PMID:2115680. |
to test the hypothesis that the antidepressant effects of total sleep deprivation (tsd) are linked to the serotonergic and/or noradrenergic system the authors carried out a double-blind study (fluvoxamine versus maprotiline) in 42 inpatients with endogenous depression (icd). |
1990-08-29 |
2023-08-11 |
Not clear |
| P Hoffmann, S Carlsson, J O Skarphedinsson, P Thoré. Role of different serotonergic receptors in the long-lasting blood pressure depression following muscle stimulation in the spontaneously hypertensive rat. Acta physiologica Scandinavica. vol 139. issue 2. 1990-08-14. PMID:2142373. |
role of different serotonergic receptors in the long-lasting blood pressure depression following muscle stimulation in the spontaneously hypertensive rat. |
1990-08-14 |
2023-08-11 |
rat |
| M Geoffroy, J Scheel-Krüger, A V Christense. Effect of imipramine in the "learned helplessness" model of depression in rats is not mimicked by combinations of specific reuptake inhibitors and scopolamine. Psychopharmacology. vol 101. issue 3. 1990-08-08. PMID:2141946. |
administration of imipramine, which blocks noradrenergic, serotonergic and cholinergic reuptake, to rats for 4 days counteracts the shuttlebox escape failures otherwise seen in rats which have been exposed to inescapable shock (the "learned helplessness" model of depression). |
1990-08-08 |
2023-08-11 |
rat |
| K P Lesch, S Mayer, J Disselkamp-Tietze, A Hoh, G Schoellnhammer, H M Schult. Subsensitivity of the 5-hydroxytryptamine1A (5-HT1A) receptor-mediated hypothermic response to ipsapirone in unipolar depression. Life sciences. vol 46. issue 18. 1990-06-29. PMID:1971701. |
the impaired hypothermic response following 5-ht1a receptor activation in unipolar depression could have resulted from subsensitivity of the (presynaptic) 5-ht1a receptor and/or related effector mechanisms, thus supporting the hypothesis that altered serotonergic activity may be present in affective disorders. |
1990-06-29 |
2023-08-11 |
human |
| M E Newman, D Drummer, B Lere. Single and combined effects of desimipramine and lithium on serotonergic receptor number and second messenger function in rat brain. The Journal of pharmacology and experimental therapeutics. vol 252. issue 2. 1990-04-16. PMID:2138225. |
it is concluded that the therapeutic action of li when added to tricyclic antidepressants in the treatment of refractory depression may partly have its basis in potentiation of effects on the serotonergic system in the brain. |
1990-04-16 |
2023-08-11 |
rat |
| H Meltze. Serotonergic dysfunction in depression. The British journal of psychiatry. Supplement. issue 8. 1990-03-15. PMID:2692637. |
serotonergic dysfunction in depression. |
1990-03-15 |
2023-08-11 |
Not clear |
| L D Van de Ka. Neuroendocrine aspects of the serotonergic hypothesis of depression. Neuroscience and biobehavioral reviews. vol 13. issue 4. 1990-02-14. PMID:2691929. |
neuroendocrine aspects of the serotonergic hypothesis of depression. |
1990-02-14 |
2023-08-11 |
Not clear |
| L D Van de Ka. Neuroendocrine aspects of the serotonergic hypothesis of depression. Neuroscience and biobehavioral reviews. vol 13. issue 4. 1990-02-14. PMID:2691929. |
dysfunction of serotonergic neurons has been implicated as one of the causes of endogenous depression. |
1990-02-14 |
2023-08-11 |
Not clear |
| S A Welner, C De Montigny, J Desroches, P Desjardins, B E Suranyi-Cadott. Autoradiographic quantification of serotonin1A receptors in rat brain following antidepressant drug treatment. Synapse (New York, N.Y.). vol 4. issue 4. 1990-01-31. PMID:2532423. |
there is growing evidence that the serotonergic (5-ht) system is involved in the pathogenesis and treatment of major depression. |
1990-01-31 |
2023-08-11 |
rat |
| G R Heninger, D S Charney, L H Price, P Delgado, S Woods, W Goodma. Effects of serotonergic agonists on neuroendocrine responses of rhesus monkeys and patients with depression and anxiety disorders. Psychopharmacology series. vol 7. 1990-01-25. PMID:2687871. |
effects of serotonergic agonists on neuroendocrine responses of rhesus monkeys and patients with depression and anxiety disorders. |
1990-01-25 |
2023-08-11 |
monkey |
| M Sano, Y Stern, J Williams, L Coté, R Rosenstein, R Mayeu. Coexisting dementia and depression in Parkinson's disease. Archives of neurology. vol 46. issue 12. 1990-01-05. PMID:2480103. |
the serotonergic system may be involved in depression and dementia because evidence of a cumulative effect on this biochemical system is present. |
1990-01-05 |
2023-08-11 |
Not clear |
| D M Stoff, L Pollock, B Vitiello, D Behar, W H Bridge. Reduction of (3H)-imipramine binding sites on platelets of conduct-disordered children. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology. vol 1. issue 1. 1989-08-17. PMID:2855302. |
we propose that a decreased platelet imipramine binding bmax value, as an index of disturbed presynaptic serotonergic activity, is not specific to depression and may be used as a biologic marker for the lack of behavioral constraint in heterogeneous. |
1989-08-17 |
2023-08-11 |
Not clear |
| E F Coccaro, L J Siever, H M Klar, G Maurer, K Cochrane, T B Cooper, R C Mohs, K L Davi. Serotonergic studies in patients with affective and personality disorders. Correlates with suicidal and impulsive aggressive behavior. Archives of general psychiatry. vol 46. issue 7. 1989-07-27. PMID:2735812. |
dysfunction of the central serotonergic system has been variously associated with depression and with suicidal and/or impulsive aggressive behavior. |
1989-07-27 |
2023-08-11 |
Not clear |
| D S Robinson, D R Alms, R C Shrotriya, M Messina, P Wickramaratn. Serotonergic anxiolytics and treatment of depression. Psychopathology. vol 22 Suppl 1. 1989-07-03. PMID:2657837. |
serotonergic anxiolytics and treatment of depression. |
1989-07-03 |
2023-08-11 |
Not clear |
| R Sandy. Serotonergic mechanisms in levodopa-induced "on-off" and sleep disorders in Parkinson's disease. The International journal of neuroscience. vol 43. issue 3-4. 1989-05-31. PMID:3243678. |
the following report concerns a 62-year-old female parkinsonian patient with levodopa-induced "on-off", depression and sleep disturbances, the severity of which was dramatically reduced by administration of low dosage amitriptyline (a serotonergic agent). |
1989-05-31 |
2023-08-11 |
Not clear |
| R C Arora, H Y Meltze. Increased serotonin2 (5-HT2) receptor binding as measured by 3H-lysergic acid diethylamide (3H-LSD) in the blood platelets of depressed patients. Life sciences. vol 44. issue 11. 1989-05-05. PMID:2927243. |
the role of serotonergic processes in the psychobiology of depression is discussed. |
1989-05-05 |
2023-08-11 |
human |
| J Butler, B E Leonar. The platelet serotonergic system in depression and following sertraline treatment. International clinical psychopharmacology. vol 3. issue 4. 1989-05-02. PMID:3235819. |
the platelet serotonergic system in depression and following sertraline treatment. |
1989-05-02 |
2023-08-11 |
Not clear |
| J Butler, B E Leonar. The platelet serotonergic system in depression and following sertraline treatment. International clinical psychopharmacology. vol 3. issue 4. 1989-05-02. PMID:3235819. |
this preliminary study examined the effect of 8 weeks' treatment with the serotonin (5ht) uptake inhibitor, sertraline, on the platelet serotonergic system in depression. |
1989-05-02 |
2023-08-11 |
Not clear |
| J Kamei, M Ogawa, Y Kasuy. Supersensitivity of 5,7-dihydroxytryptamine-treated rats to the respiratory depressant and antitussive effects of dihydrocodeine. European journal of pharmacology. vol 153. issue 2-3. 1988-12-21. PMID:3181291. |
the increased sensitivity to dihydrocodeine in terms of the depression of frequency of respiration and the cough reflex in 5,7-dht-treated rats could possibly have been due to changes in the sensitivity of serotonergic receptors. |
1988-12-21 |
2023-08-11 |
rat |
| G Curzo. Serotonergic mechanisms of depression. Clinical neuropharmacology. vol 11 Suppl 2. 1988-12-20. PMID:3052824. |
serotonergic mechanisms of depression. |
1988-12-20 |
2023-08-11 |
human |