| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| P Lichtenberg, B Shapira, D Gillon, S Kindler, T B Cooper, M E Newman, B Lere. Hormone responses to fenfluramine and placebo challenge in endogenous depression. Psychiatry research. vol 43. issue 2. 1992-11-23. PMID:1410069. |
these findings confirm previous reports and suggest that patients with endogenous major depression are characterized by central serotonergic hyporesponsivity. |
1992-11-23 |
2023-08-11 |
human |
| V Conde López, M Martínez Roi. [Azaspirodecanodiones in clinical psychiatry]. Actas luso-espanolas de neurologia, psiquiatria y ciencias afines. vol 20. issue 4. 1992-10-22. PMID:1356293. |
though its main indication is generalized anxiety disorder, it may be also useful in treating other disorders and multiple psychopathologies related to serotonergic system dysfunctions, such as depression or alcoholism. |
1992-10-22 |
2023-08-11 |
Not clear |
| E F McCance-Katz, K L Marek, L H Pric. Serotonergic dysfunction in depression associated with Parkinson's disease. Neurology. vol 42. issue 9. 1992-10-01. PMID:1387464. |
serotonergic dysfunction in depression associated with parkinson's disease. |
1992-10-01 |
2023-08-11 |
Not clear |
| E F McCance-Katz, K L Marek, L H Pric. Serotonergic dysfunction in depression associated with Parkinson's disease. Neurology. vol 42. issue 9. 1992-10-01. PMID:1387464. |
serotonergic dysfunction may be an etiologic factor in depression that occurs in parkinson's disease. |
1992-10-01 |
2023-08-11 |
Not clear |
| D H Overstreet, A H Rezvani, D S Janowsk. Genetic animal models of depression and ethanol preference provide support for cholinergic and serotonergic involvement in depression and alcoholism. Biological psychiatry. vol 31. issue 9. 1992-09-02. PMID:1386257. |
genetic animal models of depression and ethanol preference provide support for cholinergic and serotonergic involvement in depression and alcoholism. |
1992-09-02 |
2023-08-11 |
rat |
| K A Jellinger, W Paulu. Clinico-pathological correlations in Parkinson's disease. Clinical neurology and neurosurgery. vol 94 Suppl. 1992-08-12. PMID:1320531. |
more severe cell loss in the serotonergic dorsal raphe nucleus was observed in pd patients with depression than in non-depressed ones. |
1992-08-12 |
2023-08-11 |
human |
| A E Slab. Creativity, depression and suicide. Suicide & life-threatening behavior. vol 22. issue 2. 1992-08-12. PMID:1626330. |
it is suggested that the same changes in the serotonergic system that are associated with depression in general and with impulsive suicides and homicides in the extreme may also be responsible for an element of risk taking that characterizes creativity and innovation in a person psychodynamically predisposed to being creative. |
1992-08-12 |
2023-08-11 |
human |
| G D Schiller, O Pucilowski, C Wienicke, D H Overstree. Immobility-reducing effects of antidepressants in a genetic animal model of depression. Brain research bulletin. vol 28. issue 5. 1992-08-05. PMID:1617465. |
our findings support the validity of the fsl rats as an animal model of depression and suggest that serotonergic and/or noradrenergic, but not cholinergic mechanisms, may underlie the exaggerated immobility of the fsl rats. |
1992-08-05 |
2023-08-11 |
rat |
| T R Norman, F K Judd, G D Burrow. New pharmacological approaches to the management of depression: from theory to clinical practice. The Australian and New Zealand journal of psychiatry. vol 26. issue 1. 1992-06-11. PMID:1580888. |
minaprine, a compound with weak mao inhibiting properties and effects on serotonergic receptors, has clinical efficacy in the treatment of depression based on several comparative studies. |
1992-06-11 |
2023-08-11 |
Not clear |
| C M Beasley, J H Potvin, D N Masica, D E Wheadon, B E Dornseif, L A Gendus. Fluoxetine: no association with suicidality in obsessive-compulsive disorder. Journal of affective disorders. vol 24. issue 1. 1992-04-16. PMID:1545040. |
since (a) obsessive-compulsive disorder (ocd) may involve serotonergic neural transmission abnormalities also though to be related to regulation of suicide and aggression, (b) comorbidity between ocd and depression is substantial, and (c) depression is a major risk factor for suicide, a comprehensive analysis of clinical trial data was undertaken to assess the potential association of fluoxetine, a serotonin uptake inhibitor, and suicidality (suicidal acts and ideation). |
1992-04-16 |
2023-08-11 |
Not clear |
| B Shapira, B Lerer, S Kindler, P Lichtenberg, C Gropp, T Cooper, A Cale. Enhanced serotonergic responsivity following electroconvulsive therapy in patients with major depression. The British journal of psychiatry : the journal of mental science. vol 160. 1992-04-06. PMID:1540763. |
enhanced serotonergic responsivity following electroconvulsive therapy in patients with major depression. |
1992-04-06 |
2023-08-11 |
Not clear |
| E M Sellers, G A Higgins, D M Tomkins, M K Romach, T Toneatt. Opportunities for treatment of psychoactive substance use disorders with serotonergic medications. The Journal of clinical psychiatry. vol 52 Suppl. 1992-01-30. PMID:1752860. |
another way in which serotonergic medications can be used in treating substance abuse is by the treatment of comorbid psychoactive illness for which such drugs are already known to be effective, e.g., depression and anxiety disorders. |
1992-01-30 |
2023-08-11 |
Not clear |
| M Arató, E Frecska, K Tekes, D J MacCrimmo. Serotonergic interhemispheric asymmetry: gender difference in the orbital cortex. Acta psychiatrica Scandinavica. vol 84. issue 1. 1991-11-07. PMID:1927559. |
our preliminary findings--gender difference of serotonergic mechanisms in some area of the human brain--are in accordance with the observed gender differences in a variety of serotonin-regulated behaviors (sexual behavior, aggression and impulse control), and serotonergic mental disorders (eating disorders, suicidal behavior, anxiety disorders and depression). |
1991-11-07 |
2023-08-11 |
human |
| M Sano, M Stanley, A Lawton, L Coté, J Williams, Y Stern, K Marder, R Mayeu. Tritiated imipramine binding. A peripheral marker for serotonin in Parkinson's disease. Archives of neurology. vol 48. issue 10. 1991-10-29. PMID:1718247. |
this article examined this marker as a possible measure of central nervous system serotonergic activity for depression in patients with parkinson's disease (pd). |
1991-10-29 |
2023-08-11 |
Not clear |
| V O'Keane, T G Dina. Prolactin and cortisol responses to d-fenfluramine in major depression: evidence for diminished responsivity of central serotonergic function. The American journal of psychiatry. vol 148. issue 8. 1991-08-20. PMID:1853948. |
prolactin and cortisol responses to d-fenfluramine in major depression: evidence for diminished responsivity of central serotonergic function. |
1991-08-20 |
2023-08-11 |
Not clear |
| R W Fulle. Role of serotonin in therapy of depression and related disorders. The Journal of clinical psychiatry. vol 52 Suppl. 1991-06-20. PMID:1674251. |
selective inhibitors of serotonin uptake, which enhance serotonergic function by preventing the removal of serotonin from the synaptic cleft via the membrane transporter, have been introduced for the treatment of depression and may be effective in other disorders. |
1991-06-20 |
2023-08-11 |
Not clear |
| A Ontiveros, R Fontaine, R Eli. Refractory depression: the addition of lithium to fluoxetine or desipramine. Acta psychiatrica Scandinavica. vol 83. issue 3. 1991-06-14. PMID:1903237. |
the unified serotonergic and noradrenergic hypothesis for the antidepressant action could be relevant in drug-refractory depression and should be studied further. |
1991-06-14 |
2023-08-11 |
Not clear |
| R N Golden, R Ruegg, T M Brown, J Haggerty, J C Garbutt, C A Pedersen, D L Evan. Abnormal neuroendocrine responsivity to clomipramine in depression. Psychopharmacology bulletin. vol 26. issue 3. 1991-02-26. PMID:2125736. |
these observations suggest that the blunted prolactin response to clomipramine in depression is not attributable to diminished hormonal secretory capacity in anterior pituitary lactotrophs and may be a reflection of dysregulation in central serotonergic systems. |
1991-02-26 |
2023-08-11 |
human |
| S B Deshpande, J E Warnic. Interaction of thyrotropin-releasing hormone and methysergide on the monosynaptic reflex in isolated mammalian spinal cord. Neuroscience letters. vol 116. issue 1-2. 1991-01-28. PMID:2124335. |
it appears that neither mesg-induced depression nor trh-induced potentiation of the msr involves the spinal serotonergic system or blockade of k+ channels. |
1991-01-28 |
2023-08-11 |
rat |
| M S Eiso. Serotonin: a common neurobiologic substrate in anxiety and depression. Journal of clinical psychopharmacology. vol 10. issue 3 Suppl. 1990-09-05. PMID:2198299. |
it is proposed that imbalances in serotonergic neurotransmission may contribute significantly to both pathologies and that agents that act as serotonin partial agonists may normalize neurotransmission in both serotonin deficit (depression) and excess (anxiety) diseases. |
1990-09-05 |
2023-08-11 |
Not clear |