| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| G Curzo. Serotonergic mechanisms of depression. Clinical neuropharmacology. vol 11 Suppl 2. 1988-12-20. PMID:3052824. |
depression is often regarded as a result of defective serotonergic function, but it is also possible that this defect is an indication of an ineffective compensatory response to abnormally high serotonergic function. |
1988-12-20 |
2023-08-11 |
human |
| G R Heninger, D S Charney, L H Pric. Noradrenergic and serotonergic receptor system function in panic disorder and depression. Acta psychiatrica Scandinavica. Supplementum. vol 341. 1988-10-24. PMID:3048049. |
noradrenergic and serotonergic receptor system function in panic disorder and depression. |
1988-10-24 |
2023-08-11 |
Not clear |
| G R Heninger, D S Charney, L H Pric. Noradrenergic and serotonergic receptor system function in panic disorder and depression. Acta psychiatrica Scandinavica. Supplementum. vol 341. 1988-10-24. PMID:3048049. |
taken together, these studies suggest a relative abnormality in the alpha-2-adrenergic regulation of the noradrenergic system in panic disorder and a subsensitivity of the serotonergic system in depression. |
1988-10-24 |
2023-08-11 |
Not clear |
| G D Burrows, I M McIntyre, F K Judd, T R Norma. Clinical effects of serotonin reuptake inhibitors in the treatment of depressive illness. The Journal of clinical psychiatry. vol 49 Suppl. 1988-10-13. PMID:3045107. |
the serotonergic hypothesis of depression has stimulated the development of a range of chemically diverse compounds that have an exclusive effect on this neurotransmitter for potential use as antidepressant drugs. |
1988-10-13 |
2023-08-11 |
Not clear |
| A Weizman, M Mark, I Gil-Ad, S Tyano, Z Laro. Plasma cortisol, prolactin, growth hormone, and immunoreactive beta-endorphin response to fenfluramine challenge in depressed patients. Clinical neuropharmacology. vol 11. issue 3. 1988-09-21. PMID:2969772. |
the blunted cortisol responsiveness to fnf administration in depressed patients may reflect functional hypoactivity of central serotonergic system at least during the acute phase of major depression. |
1988-09-21 |
2023-08-11 |
Not clear |
| C Nyström, M Matousek, T Hällströ. Relationships between EEG and biochemical parameters in major depressive disorder. Acta psychiatrica Scandinavica. vol 77. issue 4. 1988-08-08. PMID:3389183. |
this eeg pattern is suggested to be associated with a serotonergic subgroup of depression. |
1988-08-08 |
2023-08-11 |
rat |
| O J Andy, F Jurk. Thalamic stimulation effects on reactive depression. Applied neurophysiology. vol 50. issue 1-6. 1988-06-23. PMID:3502437. |
it is concluded that depression is secondary to pain or pain-inducing factors which implicate the catecholamine and serotonergic systems. |
1988-06-23 |
2023-08-11 |
Not clear |
| J J López-Ibor, J Saiz-Ruiz, L M Iglesia. The fenfluramine challenge test in the affective spectrum: a possible marker of endogeneity and severity. Pharmacopsychiatry. vol 21. issue 1. 1988-06-09. PMID:3283785. |
in order to investigate the role of serotonergic mechanisms in depressive disorders, the fenfluramine challenge test was performed in 31 patients suffering from different types of depression. |
1988-06-09 |
2023-08-11 |
Not clear |
| H Manji, J H Brow. The antidepressant effect of beta-adrenoreceptor subsensitivity: a brief review and clinical implications. Canadian journal of psychiatry. Revue canadienne de psychiatrie. vol 32. issue 9. 1988-04-01. PMID:2830004. |
the subsensitivity requires intact noradrenergic and serotonergic systems, functionally linking the two neurotransmitters most often implicated in depression. |
1988-04-01 |
2023-08-11 |
Not clear |
| J Quintan. Platelet MAO deamination of serotonin in depressed patients. Changes after imipramine treatment and clinical correlations. Biological psychiatry. vol 23. issue 1. 1988-03-18. PMID:3337854. |
monoamine oxidase (mao) in blood platelets has been used as a model to study mao in the central nervous system, where disorders in serotonergic systems are thought to occur in depression. |
1988-03-18 |
2023-08-11 |
Not clear |
| D W Gietzen, Q R Rogers, P M Leung, B Semon, T Piechot. Serotonin and feeding responses of rats to amino acid imbalance: initial phase. The American journal of physiology. vol 253. issue 5 Pt 2. 1988-01-12. PMID:2446514. |
injection of the autoreceptor agonist, 8-hydroxy-2(di-n-propylamino)tetralin (8-oh-dpat, 500 micrograms/kg sc), to reduce transmission in the serotonergic systems resulted in an attenuation of the usual food intake depression of the amino acid-imbalanced diet (only a 7%, nonsignificant reduction). |
1988-01-12 |
2023-08-11 |
rat |
| D W Gietzen, Q R Rogers, P M Leung, B Semon, T Piechot. Serotonin and feeding responses of rats to amino acid imbalance: initial phase. The American journal of physiology. vol 253. issue 5 Pt 2. 1988-01-12. PMID:2446514. |
therefore increased serotonergic activity in some brain areas may be associated with the initial depression of food intake in rats fed an imbalanced amino acid diet. |
1988-01-12 |
2023-08-11 |
rat |
| N Bohacek, M Ravic, K Bizièr. Minaprine and imipramine in the treatment of major depressive disorders. A comparative double-blind study. Drugs under experimental and clinical research. vol 13. issue 7. 1987-11-20. PMID:3308390. |
in rodents minaprine is active in most models of depression and is thought to exert this activity by enhancing serotonergic and dopaminergic transmission. |
1987-11-20 |
2023-08-11 |
Not clear |
| C A Peabody, K F Faull, R J King, H A Whiteford, J D Barchas, P A Berge. CSF amine metabolites and depression. Psychiatry research. vol 21. issue 1. 1987-08-10. PMID:2440071. |
since lumbar csf metabolite concentrations may reflect central nervous system activity of parent amines, these data suggest a relationship between depression and decreased dopaminergic and serotonergic activity. |
1987-08-10 |
2023-08-11 |
human |
| R B Innis, D S Charney, G R Heninge. Differential 3H-imipramine platelet binding in patients with panic disorder and depression. Psychiatry research. vol 21. issue 1. 1987-08-10. PMID:3037580. |
because 3h-imi binding is associated with the serotonin reuptake site in platelet and brain membranes, these findings give further support to abnormalities in serotonergic function in patients with major depression. |
1987-08-10 |
2023-08-11 |
human |
| B Söderpalm, L Andersson, M Carlsson, K Modigh, E Eriksso. Serotonergic influence on the growth hormone response to clonidine in rat. Journal of neural transmission. vol 69. issue 1-2. 1987-07-16. PMID:3035083. |
the possibility that an impaired serotonergic neurotransmission contributes to the blunted gh responses to clonidine observed in patients suffering from endogenous depression is discussed. |
1987-07-16 |
2023-08-11 |
rat |
| M Johnson, D M Stone, G R Hanson, J W Gib. Role of the dopaminergic nigrostriatal pathway in methamphetamine-induced depression of the neostriatal serotonergic system. European journal of pharmacology. vol 135. issue 2. 1987-07-01. PMID:2884120. |
role of the dopaminergic nigrostriatal pathway in methamphetamine-induced depression of the neostriatal serotonergic system. |
1987-07-01 |
2023-08-11 |
rat |
| H M Emrich, M Berger, D Riemann, D von Zersse. Serotonin reuptake inhibition vs. norepinephrine reuptake inhibition: a double-blind differential-therapeutic study with fluvoxamine and oxaprotiline in endogenous and neurotic depressives. Pharmacopsychiatry. vol 20. issue 2. 1987-07-01. PMID:3108909. |
the data are at variance with the concept of two distinct biochemical subtypes of depression (serotonergic vs. norepinephrinergic). |
1987-07-01 |
2023-08-11 |
Not clear |
| K L Brugge, J N Hingtgen, M H Apriso. Potentiated 5-hydroxytryptophan induced response suppression in rats following chronic reserpine. Pharmacology, biochemistry, and behavior. vol 26. issue 2. 1987-06-02. PMID:3495008. |
model of depression involving the serotonergic system, we predicted the development of receptor supersensitivity of postsynaptic serotonin (5-ht) receptors due to the decreased release of this neurotransmitter as a consequence of chronic reserpine treatment. |
1987-06-02 |
2023-08-11 |
human |
| V S Kostić, B M Djuricić, N Covicković-Sternić, L Bumbasirević, M Nikolić, B B Mrsulj. Depression and Parkinson's disease: possible role of serotonergic mechanisms. Journal of neurology. vol 234. issue 2. 1987-05-12. PMID:2435855. |
depression and parkinson's disease: possible role of serotonergic mechanisms. |
1987-05-12 |
2023-08-11 |
Not clear |