| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Marta Krzyżanowska, Johann Steiner, Ralf Brisch, Christian Mawrin, Stefan Busse, Katharina Braun, Zbigniew Jankowski, Hans-Gert Bernstein, Bernhard Bogerts, Tomasz Go. Ribosomal DNA transcription in dorsal raphe nucleus neurons is increased in residual schizophrenia compared to depressed patients with affective disorders. Psychiatry research. vol 230. issue 2. 2016-06-24. PMID:26350704. |
the central serotonergic system is implicated differentially in the pathogenesis of depression and schizophrenia. |
2016-06-24 |
2023-08-13 |
Not clear |
| Leonardo Munari, Gustavo Provensi, Maria Beatrice Passani, Nicoletta Galeotti, Tommaso Cassano, Fernando Benetti, Renato Corradetti, Patrizio Blandin. Brain Histamine Is Crucial for Selective Serotonin Reuptake Inhibitors' Behavioral and Neurochemical Effects. The international journal of neuropsychopharmacology. vol 18. issue 10. 2016-06-01. PMID:25899065. |
the neurobiological changes underlying depression resistant to treatments remain poorly understood, and failure to respond to selective serotonin reuptake inhibitors may result from abnormalities of neurotransmitter systems that excite serotonergic neurons, such as histamine. |
2016-06-01 |
2023-08-13 |
Not clear |
| Bruno Carabelli, Ana Marcia Delattre, Claudia Pudell, Marco Aurélio Mori, Deborah Suchecki, Ricardo B Machado, Daniel Paulino Venancio, Sílvia Regina Piazzetta, Ivilim Hammerschmidt, Sílvio M Zanata, Marcelo M S Lima, Janaína Menezes Zanoveli, Anete Curte Ferra. The Antidepressant-Like Effect of Fish Oil: Possible Role of Ventral Hippocampal 5-HT1A Post-synaptic Receptor. Molecular neurobiology. vol 52. issue 1. 2016-05-17. PMID:25139282. |
the pathophysiology of depression is not completely understood; nonetheless, numerous studies point to serotonergic dysfunction as a possible cause. |
2016-05-17 |
2023-08-13 |
rat |
| Yeshwant Kurhe, Radhakrishnan Mahes. Ondansetron attenuates co-morbid depression and anxiety associated with obesity by inhibiting the biochemical alterations and improving serotonergic neurotransmission. Pharmacology, biochemistry, and behavior. vol 136. 2016-05-17. PMID:26188166. |
ondansetron attenuates co-morbid depression and anxiety associated with obesity by inhibiting the biochemical alterations and improving serotonergic neurotransmission. |
2016-05-17 |
2023-08-13 |
mouse |
| S W Kim, K Y Bae, J M Kim, I S Shin, Y J Hong, Y Ahn, M H Jeong, M Berk, J S Yoo. The use of statins for the treatment of depression in patients with acute coronary syndrome. Translational psychiatry. vol 5. 2016-05-11. PMID:26285130. |
in conclusion, statins may be effective for the treatment of depression independent of medical status and escitalopram use, and they may potentiate the antidepressant action of serotonergic antidepressants in patients with acs. |
2016-05-11 |
2023-08-13 |
human |
| Jingjing Song, Xintong Hou, Xinyu Hu, Chengyu Lu, Chungang Liu, Juan Wang, Wei Liu, Lirong Teng, Di Wan. Not only serotonergic system, but also dopaminergic system involved in albiflorin against chronic unpredictable mild stress-induced depression-like behavior in rats. Chemico-biological interactions. vol 242. 2016-05-03. PMID:26475043. |
all these data demonstrate that not only serotonergic system, but also dopaminergic system is involved in af-mediated antidepressant-like effect in cums-induced rat model of depression. |
2016-05-03 |
2023-08-13 |
rat |
| Noah H Green, Chad R Jackson, Hideki Iwamoto, Michael C Tackenberg, Douglas G McMaho. Photoperiod programs dorsal raphe serotonergic neurons and affective behaviors. Current biology : CB. vol 25. issue 10. 2016-04-21. PMID:25959961. |
dysregulation of serotonin neurotransmission is implicated in neurobehavioral disorders, such as depression and anxiety, and alterations in the serotonergic phenotype of raphe neurons have dramatic effects on affective behaviors in rodents. |
2016-04-21 |
2023-08-13 |
mouse |
| Rodrigo Andrade, Daniel Huereca, Joseph G Lyons, Elaine M Andrade, Kelly M McGrego. 5-HT1A Receptor-Mediated Autoinhibition and the Control of Serotonergic Cell Firing. ACS chemical neuroscience. vol 6. issue 7. 2016-04-19. PMID:25913021. |
the idea that serotonergic synaptic transmission plays an essential role in the control of mood and the pharmacotherapy of anxiety and depression is one of the cornerstones of modern biological psychiatry. |
2016-04-19 |
2023-08-13 |
Not clear |
| Dolores Vilas, Alex Iranzo, Claustre Pont-Sunyer, Mónica Serradell, Carles Gaig, Joan Santamaria, Eduardo Tolos. Brainstem raphe and substantia nigra echogenicity in idiopathic REM sleep behavior disorder with comorbid depression. Journal of neurology. vol 262. issue 7. 2016-04-11. PMID:25929659. |
this finding suggests that dysfunction of the serotonergic dorsal raphe may be involved in the pathophysiology of depression in irbd. |
2016-04-11 |
2023-08-13 |
human |
| Alessandro Ciamei, Peter J Detloff, A Jennifer Morto. Progression of behavioural despair in R6/2 and Hdh knock-in mouse models recapitulates depression in Huntington's disease. Behavioural brain research. vol 291. 2016-03-28. PMID:25986402. |
our results show that, as with depression in hd patients, floating in hd mice does not progress linearly, suggesting that, at the late stages of the disease, an increase in serotonergic and noradrenergic activity might contribute to lower floating levels in hd mice. |
2016-03-28 |
2023-08-13 |
mouse |
| Mareike Voget, Julia Rummel, Yosef Avchalumov, Reinhard Sohr, Jens K Haumesser, Ellis Rea, Aleksander A Mathé, Ravit Hadar, Christoph van Riesen, Christine Winte. Altered local field potential activity and serotonergic neurotransmission are further characteristics of the Flinders sensitive line rat model of depression. Behavioural brain research. vol 291. 2016-03-28. PMID:26025511. |
altered local field potential activity and serotonergic neurotransmission are further characteristics of the flinders sensitive line rat model of depression. |
2016-03-28 |
2023-08-13 |
rat |
| Brian E Leonar. Stress, norepinephrine and depression. Acta neuropsychiatrica. vol 14. issue 4. 2016-03-18. PMID:26984329. |
with regard to the actions of antidepressants in modulating the stress response and alleviating depression it is now evident that, irrespective of the presumed specificity of the antidepressants for the noradrenergic or serotonergic systems, they all normalize noradrenergic function. |
2016-03-18 |
2023-08-13 |
Not clear |
| L Timmerma. Panic disorder and depression: relationship between psychological and biochemical aspects. Acta neuropsychiatrica. vol 15. issue 1. 2016-03-18. PMID:26984703. |
the findings support the suggested link between aggression and depression with a low functioning serotonergic system. |
2016-03-18 |
2023-08-13 |
Not clear |
| Willemieke M Kouwenhoven, Jesse V Veenvliet, Johannes A van Hooft, L P van der Heide, Marten P Smid. Engrailed 1 shapes the dopaminergic and serotonergic landscape through proper isthmic organizer maintenance and function. Biology open. vol 5. issue 3. 2016-03-16. PMID:26879466. |
erroneous composition of dopaminergic neurons in the midbrain or serotonergic neurons in the hindbrain is associated with severe pathologies such as parkinson's disease, depression or autism. |
2016-03-16 |
2023-08-13 |
mouse |
| Takeshi Kanno, Akito Tanaka, Tomoyuki Nishizak. Linoleic acid derivative DCP-LA ameliorates stress-induced depression-related behavior by promoting cell surface 5-HT1A receptor translocation, stimulating serotonin release, and inactivating GSK-3β. Molecular neurobiology. vol 51. issue 2. 2016-03-14. PMID:24788685. |
impairment of serotonergic neurotransmission is the major factor responsible for depression and glycogen synthase kinase 3β (gsk-3β) participates in serotonergic transmission-mediated signaling networks relevant to mental illnesses. |
2016-03-14 |
2023-08-13 |
mouse |
| F Christiaens, M Mae. The TRH-test in depression: a review. Acta neuropsychiatrica. vol 4. issue 4. 2016-03-10. PMID:26956736. |
the pathophysiology underpinning an abnormal trh-test may be determined by noradrenergic (central and peripheric) or serotonergic (central) dysfunctions, thyroid hormone and cortisol hypersecretion, phenomena that are pertinent to severe depression. |
2016-03-10 |
2023-08-13 |
Not clear |
| Jae-Min Kim, Robert Stewart, Hee-Ju Kang, Kyung-Yeol Bae, Sung-Wan Kim, Il-Seon Shin, Young Joon Hong, Youngkeun Ahn, Myung Ho Jeong, Sung-Woo Park, Young-Hoon Kim, Jin-Sang Yoo. Serotonergic genes and depressive disorder in acute coronary syndrome: The Korean depression in ACS (K-DEPACS) study. European neuropsychopharmacology : the journal of the European College of Neuropsychopharmacology. vol 25. issue 6. 2016-02-16. PMID:25772786. |
serotonergic genes and depressive disorder in acute coronary syndrome: the korean depression in acs (k-depacs) study. |
2016-02-16 |
2023-08-13 |
Not clear |
| Shih-Hsien Lin, I Hui Lee, Kao Chin Chen, Po See Chen, Nan Tsing Chiu, Wei Jen Yao, Yen Kuang Yan. Serotonin transporter availability may moderate the association between perceiving stress and depressive tendencies - A SPECT with 5-HTTLPR genotyping study. Progress in neuro-psychopharmacology & biological psychiatry. vol 61. 2016-02-16. PMID:25816791. |
this finding provides new evidence that confirms the role of the serotonergic system in the association between stress and depression. |
2016-02-16 |
2023-08-13 |
human |
| I Uhl, J A Bez, T Stamm, M Pilhatsch, H-J Assion, C Norra, U Lewitzka, F Schlagenhauf, M Bauer, G Jucke. Influence of levothyroxine in augmentation therapy for bipolar depression on central serotonergic function. Pharmacopsychiatry. vol 47. issue 4-5. 2016-02-15. PMID:25002290. |
influence of levothyroxine in augmentation therapy for bipolar depression on central serotonergic function. |
2016-02-15 |
2023-08-13 |
Not clear |
| Yeshwant Kurhe, Radhakrishnan Mahesh, Deepali Gupta, Thangaraj Devados. QCM-4, a serotonergic type 3 receptor modulator attenuates depression co-morbid with obesity in mice: an approach based on behavioral and biochemical investigations. European journal of pharmacology. vol 740. 2016-02-04. PMID:24973694. |
qcm-4, a serotonergic type 3 receptor modulator attenuates depression co-morbid with obesity in mice: an approach based on behavioral and biochemical investigations. |
2016-02-04 |
2023-08-13 |
mouse |