| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Kristian Gaarn du Jardin, Heidi Kaastrup Müller, Connie Sanchez, Gregers Wegener, Betina Elfvin. A single dose of vortioxetine, but not ketamine or fluoxetine, increases plasticity-related gene expression in the rat frontal cortex. European journal of pharmacology. vol 786. 2017-03-10. PMID:27235984. |
neuroplasticity as well as serotonergic and glutamatergic signaling attain significant roles in depression pathophysiology and antidepressant responses. |
2017-03-10 |
2023-08-13 |
rat |
| b' Vjekoslav Peitl, Branka Vidrih, Zoran Karlovi\\xc4\\x87, Biserka Getaldi\\xc4\\x87, Milena Peitl, Dalibor Karlovi\\xc4\\x8. Platelet serotonin concentration and depressive symptoms in patients with schizophrenia. Psychiatry research. vol 239. 2017-02-07. PMID:27137969.' |
impaired serotonergic neurotransmission has been implicated in the pathogenesis of depression and schizophrenia. |
2017-02-07 |
2023-08-13 |
Not clear |
| Aram Rasul, Husameldin El-Nour, Sol-Britt Lonne-Rahm, Oscar Fransson, Charlotta Johansson, Björn Johansson, Marwe Zubeidi, Emma Seeberg, Diana Radu Djurfeldt, Efrain C Azmitia, Klas Nordlin. Serotonergic Markers in Atopic Dermatitis. Acta dermato-venereologica. vol 96. issue 6. 2017-01-13. PMID:26831833. |
serotonergic expression was measured in 28 patients with ad in relation to extent of the disease (scoring of atopic dermatitis; scorad), pruritus intensity (visual analogue scale; vas), anxiety traits (swedish universities scales of personality; ssp) and depression (montgomery-Åsberg depression rating scale-self assessment; madrs-s). |
2017-01-13 |
2023-08-13 |
Not clear |
| Aram Rasul, Husameldin El-Nour, Sol-Britt Lonne-Rahm, Oscar Fransson, Charlotta Johansson, Björn Johansson, Marwe Zubeidi, Emma Seeberg, Diana Radu Djurfeldt, Efrain C Azmitia, Klas Nordlin. Serotonergic Markers in Atopic Dermatitis. Acta dermato-venereologica. vol 96. issue 6. 2017-01-13. PMID:26831833. |
positive and negative correlations were found between serotonergic markers and scorad, inflammation, pruritus intensity, anxiety traits, and depression score, indicating that serotonergic mechanisms are involved in ad. |
2017-01-13 |
2023-08-13 |
Not clear |
| Hsiao-I Kuo, Walter Paulus, Giorgi Batsikadze, Asif Jamil, Min-Fang Kuo, Michael A Nitsch. Chronic Enhancement of Serotonin Facilitates Excitatory Transcranial Direct Current Stimulation-Induced Neuroplasticity. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology. vol 41. issue 5. 2016-12-14. PMID:26329381. |
chronic serotonergic enhancement results in a strengthening of ltp-like glutamatergic plasticity, which might partially explain the therapeutic impact of ssris in depression and other neuropsychiatric diseases. |
2016-12-14 |
2023-08-13 |
human |
| Robert G Frykberg, Scott Gordon, Edward Tierney, Jaminelli Bank. Linezolid-Associated Serotonin Syndrome. A Report of Two Cases. Journal of the American Podiatric Medical Association. vol 105. issue 3. 2016-12-13. PMID:26146971. |
both individuals were also undergoing treatment with at least one serotonergic agent for depression and had received this medication within 2 weeks of starting the antibiotic drug therapy. |
2016-12-13 |
2023-08-13 |
Not clear |
| Chao Dong, Ji-chun Zhang, Wei Yao, Qian Ren, Chun Yang, Min Ma, Mei Han, Ryo Saito, Kenji Hashimot. Effects of escitalopram, R-citalopram, and reboxetine on serum levels of tumor necrosis factor-α, interleukin-10, and depression-like behavior in mice after lipopolysaccharide administration. Pharmacology, biochemistry, and behavior. vol 144. 2016-12-13. PMID:26892759. |
therefore, it is likely that serotonergic system plays a key role in the pathophysiology of inflammation-induced depression. |
2016-12-13 |
2023-08-13 |
mouse |
| Jaya Thomas, Razia Khanam, Divya Vohor. Augmentation of effect of venlafaxine by folic acid in behavioral paradigms of depression in mice: Evidence of serotonergic and pro-inflammatory cytokine pathways. Pharmacological reports : PR. vol 68. issue 2. 2016-12-13. PMID:26922545. |
augmentation of effect of venlafaxine by folic acid in behavioral paradigms of depression in mice: evidence of serotonergic and pro-inflammatory cytokine pathways. |
2016-12-13 |
2023-08-13 |
mouse |
| Akiko Tamasaki, Yoshiaki Saito, Riyo Ueda, Koyo Ohno, Katsutoshi Yokoyama, Takahiro Satake, Hiroshi Sakuma, Yukitoshi Takahashi, Tatsuro Kondoh, Yoshihiro Maegak. Effects of donepezil and serotonin reuptake inhibitor on acute regression during adolescence in Down syndrome. Brain & development. vol 38. issue 1. 2016-10-05. PMID:26143664. |
we hypothesize that the acute regression in adolescence represents a process closely related to the defects of serotonergic and cholinergic systems that are innate to ds brains and not just a nonspecific comorbidity of depression or limbic encephalitis. |
2016-10-05 |
2023-08-13 |
Not clear |
| Yeshwant Kurhe, Radhakrishnan Mahes. Mechanisms linking depression co-morbid with obesity: An approach for serotonergic type 3 receptor antagonist as novel therapeutic intervention. Asian journal of psychiatry. vol 17. 2016-09-28. PMID:26243683. |
mechanisms linking depression co-morbid with obesity: an approach for serotonergic type 3 receptor antagonist as novel therapeutic intervention. |
2016-09-28 |
2023-08-13 |
Not clear |
| Yeshwant Kurhe, Radhakrishnan Mahes. Mechanisms linking depression co-morbid with obesity: An approach for serotonergic type 3 receptor antagonist as novel therapeutic intervention. Asian journal of psychiatry. vol 17. 2016-09-28. PMID:26243683. |
depression and obesity share some common pathological pathways such as hyperactivity of hypothalamic-pituitary-adrenal (hpa) axis, dysregulation of oxidant/antioxidant system balance, higher level of inflammatory cytokines, leptin resistance, altered plasma glucose, insulin resistance, reduced neuronal brain derived neurotrophic factor (bdnf) and decreased serotonergic neurotransmission in various regions of brain. |
2016-09-28 |
2023-08-13 |
Not clear |
| Yeshwant Kurhe, Radhakrishnan Mahes. Mechanisms linking depression co-morbid with obesity: An approach for serotonergic type 3 receptor antagonist as novel therapeutic intervention. Asian journal of psychiatry. vol 17. 2016-09-28. PMID:26243683. |
the present review deals with various biological mechanisms involved in depression co-morbid with obesity and 5-ht3 receptor antagonists by modulation of serotonergic system as a therapeutic target for such co-morbid disorder. |
2016-09-28 |
2023-08-13 |
Not clear |
| Stephan Köhler, Katharina Cierpinsky, Golo Kronenberg, Mazda Adl. The serotonergic system in the neurobiology of depression: Relevance for novel antidepressants. Journal of psychopharmacology (Oxford, England). vol 30. issue 1. 2016-09-26. PMID:26464458. |
the serotonergic system in the neurobiology of depression: relevance for novel antidepressants. |
2016-09-26 |
2023-08-13 |
Not clear |
| Zacharias Kohl, Nada Ben Abdallah, Jonathan Vogelgsang, Lucas Tischer, Janina Deusser, Davide Amato, Scott Anderson, Christian P Müller, Olaf Riess, Eliezer Masliah, Silke Nuber, Jürgen Winkle. Severely impaired hippocampal neurogenesis associates with an early serotonergic deficit in a BAC α-synuclein transgenic rat model of Parkinson's disease. Neurobiology of disease. vol 85. 2016-09-21. PMID:26523794. |
the dysfunction of the serotonergic system projecting to the hippocampus may contribute to early non-motor symptoms such as anxiety and depression. |
2016-09-21 |
2023-08-13 |
human |
| Melissa J Maguire, Cerian F Jackson, Anthony G Marson, Sarah J Nola. Treatments for the prevention of Sudden Unexpected Death in Epilepsy (SUDEP). The Cochrane database of systematic reviews. vol 7. 2016-09-21. PMID:27434597. |
preventative strategies for sudep include reducing the occurrence of gtcs by timely referral for presurgical evaluation in people with lesional epilepsy and advice on lifestyle measures; detecting cardiorespiratory distress through clinical observation and seizure, respiratory, and heart rate monitoring devices; preventing airway obstruction through nocturnal supervision and safety pillows; reducing central hypoventilation through physical stimulation and enhancing serotonergic mechanisms of respiratory regulation using selective serotonin reuptake inhibitors (ssris); reducing adenosine and endogenous opioid-induced brain and brainstem depression. |
2016-09-21 |
2023-08-13 |
Not clear |
| J Licinio, M-L Won. Serotonergic neurons derived from induced pluripotent stem cells (iPSCs): a new pathway for research on the biology and pharmacology of major depression. Molecular psychiatry. vol 21. issue 1. 2016-09-16. PMID:26678307. |
serotonergic neurons derived from induced pluripotent stem cells (ipscs): a new pathway for research on the biology and pharmacology of major depression. |
2016-09-16 |
2023-08-13 |
Not clear |
| Heiko Graf, Coraline D Metzger, Martin Walter, Birgit Able. Serotonergic antidepressants decrease hedonic signals but leave learning signals in the nucleus accumbens unaffected. Neuroreport. vol 27. issue 1. 2016-08-30. PMID:26555033. |
however, a global dampening of the reward system under serotonergic drugs is not intuitive considering clinical observations of their beneficial effects in the treatment of depression. |
2016-08-30 |
2023-08-13 |
human |
| Paulina Kazmierska, Jan Konopack. Development of theta rhythm in hippocampal formation slices perfused with 5-HT1A antagonist, (S)WAY 100135. Brain research. vol 1625. 2016-08-15. PMID:26358147. |
these results obtained herein of in vitro studies provide direct evidence for the involvement of serotonergic receptors in the depression of oscillatory activity in the hpc theta band. |
2016-08-15 |
2023-08-13 |
Not clear |
| Brisa S Fernandes, Jason M Hodge, Julie A Pasco, Michael Berk, Lana J William. Effects of Depression and Serotonergic Antidepressants on Bone: Mechanisms and Implications for the Treatment of Depression. Drugs & aging. vol 33. issue 1. 2016-07-25. PMID:26547857. |
effects of depression and serotonergic antidepressants on bone: mechanisms and implications for the treatment of depression. |
2016-07-25 |
2023-08-13 |
Not clear |
| Brisa S Fernandes, Jason M Hodge, Julie A Pasco, Michael Berk, Lana J William. Effects of Depression and Serotonergic Antidepressants on Bone: Mechanisms and Implications for the Treatment of Depression. Drugs & aging. vol 33. issue 1. 2016-07-25. PMID:26547857. |
the aim of this article is to review the evidence regarding the effects of depression and serotonergic antidepressants on bone and its implications for clinical care. |
2016-07-25 |
2023-08-13 |
Not clear |