| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Kristin L Szuhany, Michael W Ott. Assessing BDNF as a mediator of the effects of exercise on depression. Journal of psychiatric research. vol 123. 2021-05-14. PMID:32065946. |
assessing bdnf as a mediator of the effects of exercise on depression. |
2021-05-14 |
2023-08-13 |
human |
| Kristin L Szuhany, Michael W Ott. Assessing BDNF as a mediator of the effects of exercise on depression. Journal of psychiatric research. vol 123. 2021-05-14. PMID:32065946. |
brain-derived neurotrophic factor (bdnf) is associated with neuronal growth and reduced bdnf has been implicated in depression. |
2021-05-14 |
2023-08-13 |
human |
| Kristin L Szuhany, Michael W Ott. Assessing BDNF as a mediator of the effects of exercise on depression. Journal of psychiatric research. vol 123. 2021-05-14. PMID:32065946. |
contrary to hypotheses, change in resting bdnf or endpoint change in bdnf was not associated with changes in depression. |
2021-05-14 |
2023-08-13 |
human |
| Kristin L Szuhany, Michael W Ott. Assessing BDNF as a mediator of the effects of exercise on depression. Journal of psychiatric research. vol 123. 2021-05-14. PMID:32065946. |
overall, this study adds to the literature showing reliable effects of acute exercise on increasing bdnf and extends this research to the infrequently studied depressed population, but does not clarify the mechanism behind exercise benefits for depression. |
2021-05-14 |
2023-08-13 |
human |
| Sanne J E Bruijniks, Gerard van Grootheest, Pim Cuijpers, Hilde de Kluiver, Christiaan H Vinkers, Frenk Peeters, Brenda Penninx, Charlotte E Teunissen, Marcus J H Huiber. Working memory moderates the relation between the brain-derived neurotropic factor (BDNF) and psychotherapy outcome for depression. Journal of psychiatric research. vol 130. 2021-05-14. PMID:32891918. |
working memory moderates the relation between the brain-derived neurotropic factor (bdnf) and psychotherapy outcome for depression. |
2021-05-14 |
2023-08-13 |
Not clear |
| Sanne J E Bruijniks, Gerard van Grootheest, Pim Cuijpers, Hilde de Kluiver, Christiaan H Vinkers, Frenk Peeters, Brenda Penninx, Charlotte E Teunissen, Marcus J H Huiber. Working memory moderates the relation between the brain-derived neurotropic factor (BDNF) and psychotherapy outcome for depression. Journal of psychiatric research. vol 130. 2021-05-14. PMID:32891918. |
in addition, only in individuals with low bdnf, low working memory capacity has been associated with increased symptoms of depression. |
2021-05-14 |
2023-08-13 |
Not clear |
| Li Cai, Wentao Li, Xiaoqing Lu, Min Chen, Lingling Zhang, Yaorong Dong, Yi Li. Neural Fuyuan Formula promotes neural plasticity through BDNF/Trkβ signaling pathway. Annals of palliative medicine. vol 10. issue 3. 2021-05-14. PMID:33691458. |
this study was aimed to investigate the underline mechanism of the effect of neural fuyuan formula (nff) in post-stroke depression and the role of brain-derived neurotrophic factor (bdnf) in the signal pathway regulated by nff. |
2021-05-14 |
2023-08-13 |
Not clear |
| Neda Haghighat, Shirin Rajabi, Majid Mohammadshah. Effect of synbiotic and probiotic supplementation on serum brain-derived neurotrophic factor level, depression and anxiety symptoms in hemodialysis patients: a randomized, double-blinded, clinical trial. Nutritional neuroscience. vol 24. issue 6. 2021-05-12. PMID:31379269. |
the aim of this study was to investigate the effects of probiotic and synbiotic supplementation on the depression and anxiety symptoms and serum brain-derived neurotrophic factor (bdnf) level. |
2021-05-12 |
2023-08-13 |
Not clear |
| Guoli Wang, Yunchuan Li, Cong Lei, Xiaotong Lei, Xiaofeng Zhu, Li Yang, Ronghua Zhan. Quercetin exerts antidepressant and cardioprotective effects in estrogen receptor α-deficient female mice via BDNF-AKT/ERK1/2 signaling. The Journal of steroid biochemistry and molecular biology. vol 206. 2021-05-07. PMID:33246157. |
brain-derived neurotrophic factor (bdnf) is the potential link between depression and cardiovascular disease and estrogen receptor α (erα), an estrogen-mediated major regulator, plays an important role in protecting against depression and cardiovascular disease. |
2021-05-07 |
2023-08-13 |
mouse |
| N Prowse, Z Dwyer, A Thompson, T Fortin, K Elson, H Robeson, B Fenner, S Hayle. Early life selective knockdown of the TrkB receptor and maternal separation modulates adult stress phenotype. Behavioural brain research. vol 378. 2021-04-28. PMID:31568835. |
importantly, early life stressors that affect bdnf production are known to predispose individuals towards the later development of depression or anxiety disorders. |
2021-04-28 |
2023-08-13 |
mouse |
| Tianpeng Zheng, Bo Ge, Linyuan Qin, Bo Chen, Li Tian, Yun Gao, Liuping Xiao, Xueping Hu, Haidong Pan, Yujie Che. Association of Plasma DPP4 Activity and Brain-Derived Neurotrophic Factor With Moderate to Severe Depressive Symptoms in Patients With Type 2 Diabetes: Results From a Cross-Sectional Study. Psychosomatic medicine. vol 82. issue 4. 2021-04-26. PMID:32358323. |
increased dpp4 activity and decreased bdnf in peripheral circulation have been implicated in the pathophysiology of depression. |
2021-04-26 |
2023-08-13 |
Not clear |
| Wei Zheng, Yan-Ling Zhou, Cheng-Yu Wang, Xiao-Feng Lan, Bin Zhang, Su-Miao Zhou, Su Yan, Yu-Ping Nin. Plasma BDNF concentrations and the antidepressant effects of six ketamine infusions in unipolar and bipolar depression. PeerJ. vol 9. 2021-04-16. PMID:33850645. |
plasma bdnf concentrations and the antidepressant effects of six ketamine infusions in unipolar and bipolar depression. |
2021-04-16 |
2023-08-13 |
Not clear |
| Wei Zheng, Yan-Ling Zhou, Cheng-Yu Wang, Xiao-Feng Lan, Bin Zhang, Su-Miao Zhou, Su Yan, Yu-Ping Nin. Plasma BDNF concentrations and the antidepressant effects of six ketamine infusions in unipolar and bipolar depression. PeerJ. vol 9. 2021-04-16. PMID:33850645. |
accumulating evidence has implicated that brain derived neurotrophic factor (bdnf) is thought to be involved in the pathophysiology of depression, but its correlation with ketamine's antidepressant efficacy focusing on chinese individuals with depression is not known. |
2021-04-16 |
2023-08-13 |
Not clear |
| Stefania Zampatti, Michele Ragazzo, Carlo Fabrizio, Andrea Termine, Giulia Campoli, Valerio Caputo, Claudia Strafella, Raffaella Cascella, Carlo Caltagirone, Emiliano Giardin. Genetic Variants Allegedly Linked to Antisocial Behaviour Are Equally Distributed Across Different Populations. Journal of personalized medicine. vol 11. issue 3. 2021-04-13. PMID:33809805. |
in particular, allelic variants in slc6a4, maoa, drd4, and drd2 showed statistical associations with major depressive disorder, antisocial behaviour, schizophrenia, and bipolar disorder; bdnf polymorphic variants were associated with depressive, bipolar, and schizophrenia diseases, and tph2 variants were found both in people with unipolar depression and in children with attention deficit-hyperactivity disorder (adhd). |
2021-04-13 |
2023-08-13 |
human |
| Kensuke Nakajima, Shigeru Oiso, Hiroko Kariyazon. Brain-Derived Neurotrophic Factor Up-Regulation by the Methanol Extract of Foxtail Millet in Human Peripheral Cells. Journal of nutritional science and vitaminology. vol 66. issue 3. 2021-04-02. PMID:32612092. |
since bdnf crosses the blood-brain barrier, intake of food ingredients that elevate bdnf in peripheral tissues may be useful for the prevention and treatment of depression. |
2021-04-02 |
2023-08-13 |
human |
| Alessandra Berry, Monica Mazzelli, Chiara Musillo, Marco Andrea Riva, Annamaria Cattaneo, Francesca Cirull. High-fat diet during adulthood interacts with prenatal stress, affecting both brain inflammatory and neuroendocrine markers in male rats. The European journal of neuroscience. 2021-03-26. PMID:33711185. |
changes in the expression levels of inflammatory (il-1β, tnf-α, il-6) and of stress response mediators (nr3c1, fkbp5) as well as of mood and metabolic regulators (bdnf, ghs-r) were investigated in the hippocampus, prefrontal cortex and hypothalamus, brain regions involved in the pathogenesis of depression and prone to inflammation in response to stress. |
2021-03-26 |
2023-08-13 |
rat |
| M Polyakova, F Beyer, K Mueller, C Sander, V Witte, L Lampe, F Rodrigues, S Riedel-Heller, J Kratzsch, K T Hoffmann, A Villringer, P Schoenknecht, M L Schroete. Serum BDNF levels correlate with regional cortical thickness in minor depression: a pilot study. Scientific reports. vol 10. issue 1. 2021-03-08. PMID:32883977. |
serum bdnf levels correlate with regional cortical thickness in minor depression: a pilot study. |
2021-03-08 |
2023-08-13 |
human |
| M Polyakova, F Beyer, K Mueller, C Sander, V Witte, L Lampe, F Rodrigues, S Riedel-Heller, J Kratzsch, K T Hoffmann, A Villringer, P Schoenknecht, M L Schroete. Serum BDNF levels correlate with regional cortical thickness in minor depression: a pilot study. Scientific reports. vol 10. issue 1. 2021-03-08. PMID:32883977. |
serum bdnf positively correlated with cortical thickness and volume in multiple brain regions in the minor depression group: the bilateral medial orbitofrontal cortex and rostral anterior cingulate cortex, left insula, and cingulum, right superior frontal gyrus, and other regions-regions typically affected by major depression. |
2021-03-08 |
2023-08-13 |
human |
| M Polyakova, F Beyer, K Mueller, C Sander, V Witte, L Lampe, F Rodrigues, S Riedel-Heller, J Kratzsch, K T Hoffmann, A Villringer, P Schoenknecht, M L Schroete. Serum BDNF levels correlate with regional cortical thickness in minor depression: a pilot study. Scientific reports. vol 10. issue 1. 2021-03-08. PMID:32883977. |
our findings point to a specific association between serum bdnf and magnetic resonance imaging parameters in first-episode minor depression in a region- and condition-dependent manner. |
2021-03-08 |
2023-08-13 |
human |
| Young-Ju Lee, Hye Ryeong Kim, Chang Youn Lee, Sung-Ae Hyun, Moon Yi Ko, Byoung-Seok Lee, Dae Youn Hwang, Minhan K. 2-Phenylethylamine (PEA) Ameliorates Corticosterone-Induced Depression-Like Phenotype via the BDNF/TrkB/CREB Signaling Pathway. International journal of molecular sciences. vol 21. issue 23. 2021-03-05. PMID:33265983. |
here, we show that pea exerts antidepressant effects by modulating the brain-derived neurotrophic factor (bdnf)/tropomyosin receptor kinase b (trkb)/camp response element binding protein (creb) signaling pathway in cort-induced depression. |
2021-03-05 |
2023-08-13 |
mouse |