| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Ying Xue, Hongyan Liang, Rui Yang, Kunhong Deng, Mimi Tang, Mengqi Zhan. The role of pro- and mature neurotrophins in the depression. Behavioural brain research. vol 404. 2021-09-02. PMID:33549684. |
more importantly, we expounded the physiology and pathology mechanisms of brain-derived neurotrophic factor(bdnf)in depression. |
2021-09-02 |
2023-08-13 |
Not clear |
| Yang Liu, Zufang Wu, Lu Cheng, Xin Zhang, Haining Yan. The role of the intestinal microbiota in the pathogenesis of host depression and mechanism of TPs relieving depression. Food & function. vol 12. issue 17. 2021-09-02. PMID:34286799. |
alterations in the intestinal flora composition could increase the permeability of the gut barrier, activate systemic inflammation and immune responses, regulate the release and efficacy of monoamine neurotransmitters, alter the activity and function of the hypothalamic-pituitary-adrenal (hpa) axis, and modify the abundance of the brain-derived neurotrophic factor (bdnf); all of these showed a close correlation with the occurrence of depression. |
2021-09-02 |
2023-08-13 |
Not clear |
| Xiaochen Du, Wei Chen, Na Zhan, Xiguo Bian, Wenbing Y. The effects of low-intensity resistance training with or without blood flow restriction on serum BDNF, VEGF and perception in patients with post-stroke depression. Neuro endocrinology letters. vol 42. issue 4. 2021-08-28. PMID:34436843. |
the effects of low-intensity resistance training with or without blood flow restriction on serum bdnf, vegf and perception in patients with post-stroke depression. |
2021-08-28 |
2023-08-13 |
Not clear |
| Xiaochen Du, Wei Chen, Na Zhan, Xiguo Bian, Wenbing Y. The effects of low-intensity resistance training with or without blood flow restriction on serum BDNF, VEGF and perception in patients with post-stroke depression. Neuro endocrinology letters. vol 42. issue 4. 2021-08-28. PMID:34436843. |
post-stroke depression (psd) has a significant effect on patients' quality of life and is often accompanied by a decrease in serum brain-derived neurotrophic factor (bdnf) and vascular endothelial growth factor (vegf) levels. |
2021-08-28 |
2023-08-13 |
Not clear |
| Patrick Mucher, Delgerdalai Batmyagmar, Thomas Perkmann, Manuela Repl, Astrid Radakovics, Elisabeth Ponocny-Seliger, Ina Lukas, Monika Fritzer-Szekeres, Johann Lehrner, Thomas Knogler, Dimiter Tscholakoff, Martina Fondi, Oswald F Wagner, Robert Winker, Helmuth Haslache. Basal myokine levels are associated with quality of life and depressed mood in older adults. Psychophysiology. vol 58. issue 5. 2021-08-20. PMID:33655551. |
serum interleukin-6 (il-6), irisin, brain-derived neurotrophic factor (bdnf), kynurenine, and cathepsin b were analyzed and compared to surrogates of depression and quality of life. |
2021-08-20 |
2023-08-13 |
Not clear |
| Sang-Kap Han, Jeon-Kyung Kim, Hee-Seo Park, Yeun-Jeong Shin, Dong-Hyun Ki. Chaihu-Shugan-San (Shihosogansan) alleviates restraint stress-generated anxiety and depression in mice by regulating NF-κB-mediated BDNF expression through the modulation of gut microbiota. Chinese medicine. vol 16. issue 1. 2021-08-19. PMID:34391441. |
chaihu-shugan-san (shihosogansan) alleviates restraint stress-generated anxiety and depression in mice by regulating nf-κb-mediated bdnf expression through the modulation of gut microbiota. |
2021-08-19 |
2023-08-13 |
mouse |
| Silvia Martinelli, Elmira A Anderzhanova, Thomas Bajaj, Svenja Wiechmann, Frederik Dethloff, Katja Weckmann, Daniel E Heinz, Tim Ebert, Jakob Hartmann, Thomas M Geiger, Michael Döngi, Kathrin Hafner, Max L Pöhlmann, Lee Jollans, Alexandra Philipsen, Susanne V Schmidt, Ulrike Schmidt, Giuseppina Maccarrone, Valentin Stein, Felix Hausch, Christoph W Turck, Mathias V Schmidt, Anne-Kathrin Gellner, Bernhard Kuster, Nils C Gasse. Stress-primed secretory autophagy promotes extracellular BDNF maturation by enhancing MMP9 secretion. Nature communications. vol 12. issue 1. 2021-08-17. PMID:34330919. |
bdnf is essential for adult synaptic plasticity and its pathway is associated with major depression and posttraumatic stress disorder. |
2021-08-17 |
2023-08-13 |
Not clear |
| Eugenia Murawska-Ciałowicz, Mona Wiatr, Maria Ciałowicz, Gilmara Gomes de Assis, Wojciech Borowicz, Silvia Rocha-Rodrigues, Małgorzata Paprocka-Borowicz, Adilson Marque. BDNF Impact on Biological Markers of Depression-Role of Physical Exercise and Training. International journal of environmental research and public health. vol 18. issue 14. 2021-08-11. PMID:34300001. |
the aim of this review was to provide information of the biological markers of depression such as monoamines, tryptophan, endocannabinoids, markers of inflammatory processes (oxidative stress and cytokines) stress and sex hormones and their relationship to bdnf. |
2021-08-11 |
2023-08-13 |
Not clear |
| Yunxuan Xu, Lingyun Lian. Vitamin D3/vitamin D receptor signaling mitigates symptoms of post-stroke depression in mice by upregulating hippocampal BDNF expression. Neuroscience research. vol 170. 2021-08-04. PMID:32882254. |
vitamin d3/vitamin d receptor signaling mitigates symptoms of post-stroke depression in mice by upregulating hippocampal bdnf expression. |
2021-08-04 |
2023-08-13 |
mouse |
| Vlad Dionisie, Adela Magdalena Ciobanu, Vlad Alexandru Toma, Mihnea Costin Manea, Ioana Baldea, Diana Olteanu, Alexandra Sevastre-Berghian, Simona Clichici, Mirela Manea, Sorin Riga, Gabriela Adriana Fili. Escitalopram Targets Oxidative Stress, Caspase-3, BDNF and MeCP2 in the Hippocampus and Frontal Cortex of a Rat Model of Depression Induced by Chronic Unpredictable Mild Stress. International journal of molecular sciences. vol 22. issue 14. 2021-07-30. PMID:34299103. |
escitalopram targets oxidative stress, caspase-3, bdnf and mecp2 in the hippocampus and frontal cortex of a rat model of depression induced by chronic unpredictable mild stress. |
2021-07-30 |
2023-08-13 |
rat |
| Tatiana A Gudasheva, Anna V Tallerova, Armen G Mezhlumyan, Tatyana A Antipova, Ilya O Logvinov, Yulia N Firsova, Polina Y Povarnina, Sergey B Seredeni. Low-Molecular Weight BDNF Mimetic, Dimeric Dipeptide GSB-106, Reverses Depressive Symptoms in Mouse Chronic Social Defeat Stress. Biomolecules. vol 11. issue 2. 2021-07-23. PMID:33578683. |
thus, the present results demonstrate the dipeptide bdnf mimetic gsb-106 reversed depressive-like behavior and restored hippocampal neuroplasticity in a rodent depression model. |
2021-07-23 |
2023-08-13 |
mouse |
| Jennifer L Reed, Tasuku Terada, Lisa M Cotie, Heather E Tulloch, Frans H Leenen, Matheus Mistura, Harleen Hans, Hong-Wei Wang, Sol Vidal-Almela, Robert D Reid, Andrew L Pip. The effects of high-intensity interval training, Nordic walking and moderate-to-vigorous intensity continuous training on functional capacity, depression and quality of life in patients with coronary artery disease enrolled in cardiac rehabilitation: A randomized controlled trial (CRX study). Progress in cardiovascular diseases. 2021-07-20. PMID:34245777. |
the effects on depression severity, brain-derived neurotrophic factor (bdnf) and qol were also examined. |
2021-07-20 |
2023-08-13 |
Not clear |
| Sonani Mindt, Michael Neumaier, Rainer Hellweg, Alexander Sartorius, Laura Kranaste. Brain-Derived Neurotrophic Factor in the Cerebrospinal Fluid Increases During Electroconvulsive Therapy in Patients With Depression: A Preliminary Report. The journal of ECT. vol 36. issue 3. 2021-07-16. PMID:32118691. |
we measured bdnf levels from the cerebrospinal fluid (csf) in patients with major depression before and shortly after a course of ect. |
2021-07-16 |
2023-08-13 |
Not clear |
| Eero Castrén, Lisa M Monteggi. Brain-Derived Neurotrophic Factor Signaling in Depression and Antidepressant Action. Biological psychiatry. vol 90. issue 2. 2021-07-16. PMID:34053675. |
neurotrophic factors, particularly bdnf (brain-derived neurotrophic factor), have been associated with depression and antidepressant drug action. |
2021-07-16 |
2023-08-13 |
Not clear |
| Hongxiu Zhang, Xiansu Chi, Wenchao Pan, Shijun Wang, Zhe Zhang, Haijun Zhao, Yuan Wang, Zhichun Wu, Miaomiao Zhou, Shan Ma, Qitao Zhao, Ke M. Antidepressant mechanism of classical herbal formula lily bulb and Rehmannia decoction: insights from gene expression profile of medial prefrontal cortex of mice with stress-induced depression-like behavior. Genes, brain, and behavior. vol 19. issue 5. 2021-07-15. PMID:32129566. |
gabaergic and glutamatergic synapses as well as brain-derived neurotrophic factor (bdnf)/trkb-dependent phosphoinositide 3-kinase (pi3k)/akt/mammalian target of rapamycin-1 (mtor1), might be the main signaling pathways underlying the multi-target therapeutic effects of lbrd against depression. |
2021-07-15 |
2023-08-13 |
mouse |
| Francisco Campos-Rodriguez, Jose Cordero-Guevara, Maria Isabel Asensio-Cruz, Angeles Sanchez-Armengol, Veronica Sanchez-Lopez, Elena Arellano-Orden, David Gozal, Miguel Angel Martinez-Garci. Interleukin 6 as a marker of depression in women with sleep apnea. Journal of sleep research. vol 30. issue 1. 2021-07-13. PMID:32212220. |
associations between tumour necrosis factor α (tnfα), interleukin 6 (il-6), c-reactive protein (crp), intercellular adhesion molecule 1 (icam-1), catalase (cat), superoxide dismutase (sod) and brain-derived neurotrophic factor (bdnf) plasma levels and depression were assessed. |
2021-07-13 |
2023-08-13 |
cat |
| Eric Zhang, Ping Lia. Brain-derived neurotrophic factor and post-stroke depression. Journal of neuroscience research. vol 98. issue 3. 2021-07-12. PMID:31385340. |
furthermore, antidepressants could enhance bdnf expression in the brain, resulting in an alleviation of depression symptoms. |
2021-07-12 |
2023-08-13 |
Not clear |
| Naheed Akhter, Mehir Un Nisa Iqbal, Aliya Maqsood, Safdar Ali Sheikh, Anwar Ali, Taseer Ahmed Kha. Association of BDNF and SERT gene polymorphisms with depression among Pakistani population. Pakistan journal of pharmaceutical sciences. vol 34. issue 1. 2021-07-12. PMID:34248009. |
association of bdnf and sert gene polymorphisms with depression among pakistani population. |
2021-07-12 |
2023-08-13 |
human |
| Naheed Akhter, Mehir Un Nisa Iqbal, Aliya Maqsood, Safdar Ali Sheikh, Anwar Ali, Taseer Ahmed Kha. Association of BDNF and SERT gene polymorphisms with depression among Pakistani population. Pakistan journal of pharmaceutical sciences. vol 34. issue 1. 2021-07-12. PMID:34248009. |
brain-derived neurotrophic factor (bdnf) and serotonin transporter (sert) is implicated in the adverse life events which lead to depression. |
2021-07-12 |
2023-08-13 |
human |
| Naheed Akhter, Mehir Un Nisa Iqbal, Aliya Maqsood, Safdar Ali Sheikh, Anwar Ali, Taseer Ahmed Kha. Association of BDNF and SERT gene polymorphisms with depression among Pakistani population. Pakistan journal of pharmaceutical sciences. vol 34. issue 1. 2021-07-12. PMID:34248009. |
the variation in genetic make-up of bdnf (val66met) and sert (5'-httlpr) are potential biomarkers in the development of neuropsychiatric disorders including depression. |
2021-07-12 |
2023-08-13 |
human |