| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Naheed Akhter, Mehir Un Nisa Iqbal, Aliya Maqsood, Safdar Ali Sheikh, Anwar Ali, Taseer Ahmed Kha. Association of BDNF and SERT gene polymorphisms with depression among Pakistani population. Pakistan journal of pharmaceutical sciences. vol 34. issue 1. 2021-07-12. PMID:34248009. |
the purpose of this study was to investigate the correlation of functional polymorphisms of bdnf and sert genes with depression among pakistani population. |
2021-07-12 |
2023-08-13 |
human |
| Naheed Akhter, Mehir Un Nisa Iqbal, Aliya Maqsood, Safdar Ali Sheikh, Anwar Ali, Taseer Ahmed Kha. Association of BDNF and SERT gene polymorphisms with depression among Pakistani population. Pakistan journal of pharmaceutical sciences. vol 34. issue 1. 2021-07-12. PMID:34248009. |
however, sert 'sl' (or: 1.150, 95%ci: 0.601-2.201) and bdnf 'aa' (or: 1.651, 95%ci: 0.585-4.660) and 'ga' (or: 2.279, 95%ci: 0.825-6.298) genotypes might be a risk genotypes for depression. |
2021-07-12 |
2023-08-13 |
human |
| Naheed Akhter, Mehir Un Nisa Iqbal, Aliya Maqsood, Safdar Ali Sheikh, Anwar Ali, Taseer Ahmed Kha. Association of BDNF and SERT gene polymorphisms with depression among Pakistani population. Pakistan journal of pharmaceutical sciences. vol 34. issue 1. 2021-07-12. PMID:34248009. |
hence, it is concluded that the functional bdnf (val66met) and sert (5'-httlpr) gene polymorphisms may not be associated with depression. |
2021-07-12 |
2023-08-13 |
human |
| Eman Soliman, Nariman Essmat, Mona F Mahmoud, Amr A A Mahmou. Impact of some oral hypoglycemic agents on type 2 diabetes-associated depression and reserpine-induced depression in rats: the role of brain oxidative stress and inflammation. Naunyn-Schmiedeberg's archives of pharmacology. vol 393. issue 8. 2021-07-06. PMID:32077986. |
antidiabetic agents reduced diabetes-associated depression as indicated by the reduction in the immobility time in the forced swim test, elevation of cortical and hippocampal serotonin and brain-derived neurotrophic factor (bdnf), and the increase in serum β-amyloid 1-42 (aβ1-42) levels. |
2021-07-06 |
2023-08-13 |
rat |
| Yue Wang, Yan Li, Zhonghao Wu, Zhi Chen, Heming Yu, Yong He, Yu Tian, Tianlan Lan, Mengge Bai, Xiangyu Chen, Ke Cheng, Peng Xi. Ferritin disorder in the plasma and hippocampus associated with major depressive disorder. Biochemical and biophysical research communications. vol 553. 2021-07-06. PMID:33765555. |
rodent and nonhuman primate-based depression models have been studied, such as brain-derived neurotrophic factor (bdnf) and monoamine acid disorder hypotheses, as well as peripheral microbiota disturbances causing mdd; however, the pathogenesis is still largely unknown. |
2021-07-06 |
2023-08-13 |
mouse |
| Asami Ohto, Yoshito Mizoguchi, Yoshiomi Imamura, Naoki Kojima, Shigeto Yamada, Akira Monj. No association of both serum pro-brain-derived neurotrophic factor (proBDNF) and BDNF concentrations with depressive state in community-dwelling elderly people. Psychogeriatrics : the official journal of the Japanese Psychogeriatric Society. vol 21. issue 4. 2021-07-05. PMID:33878808. |
low-bdnf levels occur in patients with depression, while probdnf, a precursor of bdnf with the opposite physiological function, increases in major depression. |
2021-07-05 |
2023-08-13 |
Not clear |
| Asami Ohto, Yoshito Mizoguchi, Yoshiomi Imamura, Naoki Kojima, Shigeto Yamada, Akira Monj. No association of both serum pro-brain-derived neurotrophic factor (proBDNF) and BDNF concentrations with depressive state in community-dwelling elderly people. Psychogeriatrics : the official journal of the Japanese Psychogeriatric Society. vol 21. issue 4. 2021-07-05. PMID:33878808. |
however, it is unclear whether bdnf and probdnf are associated with depression in the elderly. |
2021-07-05 |
2023-08-13 |
Not clear |
| Hideyuki Matsumoto, Yoshikazu Ugaw. Quadripulse stimulation (QPS). Experimental brain research. vol 238. issue 7-8. 2021-06-29. PMID:32211927. |
in this mini-review, we briefly introduce qps: (i) principle and cortical plasticity (stimulators and protocols, synaptic plasticity, underlying mechanisms, meta-plasticity, axonal plasticity, and drug effects), (ii) robust and strong neural plasticity induction (variability, influence of phasic muscle contraction, independency of bdnf polymorphism, sensory cortical plasticity, neural plasticity in the contralateral hemisphere, on-line effects on the brain networks, studies of normal brain physiology, and visuomotor sequence learning), (iii) therapeutic applications to neurological and psychiatric disorders (parkinson's disease, epilepsy, cerebrovascular disease, and major depression), (iv) safety, and (v) future issues. |
2021-06-29 |
2023-08-13 |
Not clear |
| Ronald S Duman, Satoshi Deyama, Manoela Viar Fogaç. Role of BDNF in the pathophysiology and treatment of depression: Activity-dependent effects distinguish rapid-acting antidepressants. The European journal of neuroscience. vol 53. issue 1. 2021-06-28. PMID:31811669. |
role of bdnf in the pathophysiology and treatment of depression: activity-dependent effects distinguish rapid-acting antidepressants. |
2021-06-28 |
2023-08-13 |
Not clear |
| Ronald S Duman, Satoshi Deyama, Manoela Viar Fogaç. Role of BDNF in the pathophysiology and treatment of depression: Activity-dependent effects distinguish rapid-acting antidepressants. The European journal of neuroscience. vol 53. issue 1. 2021-06-28. PMID:31811669. |
here, we review the literature demonstrating that exposure to stress and depression decreases bdnf expression in the hippocampus and pfc and conversely that antidepressant treatment can up-regulate bdnf in the adult brain and reverse the effects of stress. |
2021-06-28 |
2023-08-13 |
Not clear |
| Martin Pedard, Aurore Quirié, Anne Tessier, Philippe Garnier, Perle Totoson, Céline Demougeot, Christine Mari. A reconciling hypothesis centred on brain-derived neurotrophic factor to explain neuropsychiatric manifestations in rheumatoid arthritis. Rheumatology (Oxford, England). vol 60. issue 4. 2021-06-28. PMID:33313832. |
however, converging evidence strongly suggests that deficit in brain-derived neurotrophic factor (bdnf) signalling contributes to impaired cognition and depression. |
2021-06-28 |
2023-08-13 |
Not clear |
| Wei Yao, Song Lin, Jin Su, Qianqian Cao, Yueyue Chen, Jiaxu Chen, Zhentao Zhang, Kenji Hashimoto, Qi Qi, Ji-Chun Zhan. Activation of BDNF by transcription factor Nrf2 contributes to antidepressant-like actions in rodents. Translational psychiatry. vol 11. issue 1. 2021-06-28. PMID:33627628. |
the transcription factor erythroid 2-related factor 2 (nrf2) and brain-derived neurotrophic factor (bdnf) play a key role in depression. |
2021-06-28 |
2023-08-13 |
mouse |
| Wei Yao, Song Lin, Jin Su, Qianqian Cao, Yueyue Chen, Jiaxu Chen, Zhentao Zhang, Kenji Hashimoto, Qi Qi, Ji-Chun Zhan. Activation of BDNF by transcription factor Nrf2 contributes to antidepressant-like actions in rodents. Translational psychiatry. vol 11. issue 1. 2021-06-28. PMID:33627628. |
however, the molecular mechanisms underlying the crosstalk between nrf2 and bdnf in depression remain unclear. |
2021-06-28 |
2023-08-13 |
mouse |
| Lílian Viana Dos Santos Azevedo, Jéssica Ramos Pereira, Renata Maria Silva Santos, Natalia Pessoa Rocha, Antônio Lúcio Teixeira, Paulo Pereira Christo, Victor Rodrigues Santos, Paula Luciana Scalz. Acute exercise increases BDNF serum levels in patients with Parkinson's disease regardless of depression or fatigue. European journal of sport science. 2021-06-28. PMID:33944700. |
acute exercise increases bdnf serum levels in patients with parkinson's disease regardless of depression or fatigue. |
2021-06-28 |
2023-08-13 |
Not clear |
| Lílian Viana Dos Santos Azevedo, Jéssica Ramos Pereira, Renata Maria Silva Santos, Natalia Pessoa Rocha, Antônio Lúcio Teixeira, Paulo Pereira Christo, Victor Rodrigues Santos, Paula Luciana Scalz. Acute exercise increases BDNF serum levels in patients with Parkinson's disease regardless of depression or fatigue. European journal of sport science. 2021-06-28. PMID:33944700. |
generalized estimating equation (gee) showed a significant effect of time (pre- vs. post-exercise) when compared individuals with vs. without depression [wald chi square (4.392), p = 0.036)] and with vs. without fatigue [wald chi square (7.123), p = 0.008)] for mature bdnf (mbdnf) level. |
2021-06-28 |
2023-08-13 |
Not clear |
| Ting Lei, Dan Dong, Meiying Song, Yanfei Sun, Xiaofeng Liu, Hua Zha. Rislenemdaz treatment in the lateral habenula improves despair-like behavior in mice. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology. vol 45. issue 10. 2021-06-23. PMID:32147667. |
given the important role of the lateral habenula (lhb) in the pathogenesis of depression and the fact that glun2b-containing n-methyl-d-aspartate receptors and brain-derived neurotrophic factor (bdnf) are expressed in the lhb, we conducted a study to examine whether the lhb mediates ris' antidepressant effects in a chronic restraint stress (crs)-induced depressive-like mouse model. |
2021-06-23 |
2023-08-13 |
mouse |
| A G Sartim, M A Sartim, R D Cummings, M Dias-Baruffi, S R Joc. Impaired emotional response to stress in mice lacking galectin-1 or galectin-3. Physiology & behavior. vol 220. 2021-06-21. PMID:32156558. |
gal-1 induces the expression of the brain-derived neurotrophic factor (bdnf) and promotes adult neural stem cells proliferation, biological events impaired in stress-related psychiatric disorders, such as depression and anxiety. |
2021-06-21 |
2023-08-13 |
mouse |
| Dan Shan, YuanDian Zheng, Karen Frou. Brain-Derived Neurotrophic Factor as a Clinical Biomarker in Predicting the Development of Post-Stroke Depression: A Review of Evidence. Cureus. vol 13. issue 6. 2021-06-19. PMID:34141514. |
studying the relationship between brain-derived neurotrophic factor (bdnf) and post-stroke depression (psd) may help determine the potential for depression in stroke patients at the earliest stage possible. |
2021-06-19 |
2023-08-13 |
Not clear |
| Dan Shan, YuanDian Zheng, Karen Frou. Brain-Derived Neurotrophic Factor as a Clinical Biomarker in Predicting the Development of Post-Stroke Depression: A Review of Evidence. Cureus. vol 13. issue 6. 2021-06-19. PMID:34141514. |
we conducted a search in the electronic databases pubmed, embase, and psycinfo (all records from january 1, 2000, through october 20, 2020) using keywords: "brain-derived neurotrophic factor or bdnf," "post-stroke depression or psd," "expression level," "association," and "relationship. |
2021-06-19 |
2023-08-13 |
Not clear |
| Dan Shan, YuanDian Zheng, Karen Frou. Brain-Derived Neurotrophic Factor as a Clinical Biomarker in Predicting the Development of Post-Stroke Depression: A Review of Evidence. Cureus. vol 13. issue 6. 2021-06-19. PMID:34141514. |
overall, this review reveals associations between changes in serum bdnf levels and depression following stroke. |
2021-06-19 |
2023-08-13 |
Not clear |