| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Yixian Huang, Caili Huang, Qilin Zhang, Wenqi Wu, Jiawei Su. Serum BDNF discriminates Parkinson's disease patients with depression from without depression and reflect motor severity and gender differences. Journal of neurology. vol 268. issue 4. 2021-06-18. PMID:33179143. |
serum bdnf discriminates parkinson's disease patients with depression from without depression and reflect motor severity and gender differences. |
2021-06-18 |
2023-08-13 |
Not clear |
| Yixian Huang, Caili Huang, Qilin Zhang, Wenqi Wu, Jiawei Su. Serum BDNF discriminates Parkinson's disease patients with depression from without depression and reflect motor severity and gender differences. Journal of neurology. vol 268. issue 4. 2021-06-18. PMID:33179143. |
to evaluate the diagnostic value of serum brain-derived neurotrophic factor (bdnf) levels for discriminating pd with depression from without depression, and to investigate whether serum bdnf levels were associated with motor severity and gender in depressed pd patients. |
2021-06-18 |
2023-08-13 |
Not clear |
| Xiaonan Zhang, Ying Xue, Jinying Li, Hong Xu, Wei Yan, Ziwei Zhao, Weizhi Yu, Xiuli Zhai, Ye Sun, Yi Wu, Yufei Li, Lin Gui, Deqin Yu, Zhaoyang Xiao, Shengming Yi. The involvement of ADAR1 in antidepressant action by regulating BDNF via miR-432. Behavioural brain research. vol 402. 2021-06-18. PMID:33412228. |
brain-derived neurotrophic factor (bdnf) is a biomarker of depression. |
2021-06-18 |
2023-08-13 |
mouse |
| Hayley Dingsdale, Xinsheng Nan, Samantha M Garay, Annett Mueller, Lorna A Sumption, Pedro Chacón-Fernández, Isabel Martinez-Garay, Cedric Ghevaert, Yves-Alain Barde, Rosalind M Joh. The placenta protects the fetal circulation from anxiety-driven elevations in maternal serum levels of brain-derived neurotrophic factor. Translational psychiatry. vol 11. issue 1. 2021-06-18. PMID:33462179. |
numerous studies report alterations in bdnf levels in human serum in various neurological conditions, including mood disorders such as depression. |
2021-06-18 |
2023-08-13 |
mouse |
| Hayley Dingsdale, Xinsheng Nan, Samantha M Garay, Annett Mueller, Lorna A Sumption, Pedro Chacón-Fernández, Isabel Martinez-Garay, Cedric Ghevaert, Yves-Alain Barde, Rosalind M Joh. The placenta protects the fetal circulation from anxiety-driven elevations in maternal serum levels of brain-derived neurotrophic factor. Translational psychiatry. vol 11. issue 1. 2021-06-18. PMID:33462179. |
we asked whether maternal depression and/or anxiety during pregnancy were associated with altered serum bdnf levels in mothers (n = 251) and their new-born infants (n = 212). |
2021-06-18 |
2023-08-13 |
mouse |
| Hayley Dingsdale, Xinsheng Nan, Samantha M Garay, Annett Mueller, Lorna A Sumption, Pedro Chacón-Fernández, Isabel Martinez-Garay, Cedric Ghevaert, Yves-Alain Barde, Rosalind M Joh. The placenta protects the fetal circulation from anxiety-driven elevations in maternal serum levels of brain-derived neurotrophic factor. Translational psychiatry. vol 11. issue 1. 2021-06-18. PMID:33462179. |
we found no association between maternal symptoms of depression and either maternal or infant cord blood serum bdnf. |
2021-06-18 |
2023-08-13 |
mouse |
| Barbara L Pitts, Vivian Wen, Julia M Whealin, Brienna M Fogle, Steven M Southwick, Irina Esterlis, Robert H Pietrza. Depression and Cognitive Dysfunction in Older U.S. Military Veterans: Moderating Effects of BDNF Val66Met Polymorphism and Physical Exercise. The American journal of geriatric psychiatry : official journal of the American Association for Geriatric Psychiatry. vol 28. issue 9. 2021-06-14. PMID:32122804. |
depression and cognitive dysfunction in older u.s. military veterans: moderating effects of bdnf val66met polymorphism and physical exercise. |
2021-06-14 |
2023-08-13 |
Not clear |
| Mahino Fatima, Mir Hilal Ahmad, Saurabh Srivastav, Moshahid Alam Rizvi, A C Monda. A selective D2 dopamine receptor agonist alleviates depression through up-regulation of tyrosine hydroxylase and increased neurogenesis in hippocampus of the prenatally stressed rats. Neurochemistry international. vol 136. 2021-06-07. PMID:32201282. |
pns induced changes resulted in depression validated by the depression-like behaviours, increased oxidative stress, decreased th expression, altered expression of selective developmental genes, along with the reduced hippocampal neurogenesis and bdnf expression in the brain of adult offsprings. |
2021-06-07 |
2023-08-13 |
rat |
| Jing Liu, Fantao Meng, Juanjuan Dai, Min Wu, Wentao Wang, Cuilan Liu, Di Zhao, Hongcai Wang, Jingyan Zhang, Chen L. The BDNF-FoxO1 Axis in the medial prefrontal cortex modulates depressive-like behaviors induced by chronic unpredictable stress in postpartum female mice. Molecular brain. vol 13. issue 1. 2021-06-04. PMID:32532322. |
the brain-derived neurotrophic factor (bdnf) gene is an important target gene for the study of depression and antidepressant therapy. |
2021-06-04 |
2023-08-13 |
mouse |
| Yun Wang, Ce Gao, Tianyu Gao, Lu Zhao, Shiguang Zhu, Lin Gu. Plasma exosomes from depression ameliorate inflammation-induced depressive-like behaviors via sigma-1 receptor delivery. Brain, behavior, and immunity. vol 94. 2021-05-28. PMID:33607235. |
our results revealed that injection of exosomes from depression models or patients rather than normal controls significantly ameliorated depressive-like behaviors, deficiency of bdnf expression and neuro-inflammation in lps-challenged mice. |
2021-05-28 |
2023-08-13 |
mouse |
| Shuxin Luan, Bing Zhou, Qiong Wu, Hongquan Wan, He L. Brain-derived neurotrophic factor blood levels after electroconvulsive therapy in patients with major depressive disorder: A systematic review and meta-analysis. Asian journal of psychiatry. vol 51. 2021-05-27. PMID:32146142. |
the following key words were used: "depression" or "depressive disorder", "major depressive disorder", "unipolar depression", "brain-derived neurotrophic factor" or "bdnf", and "electroconvulsive" or "ect". |
2021-05-27 |
2023-08-13 |
Not clear |
| Shuxin Luan, Bing Zhou, Qiong Wu, Hongquan Wan, He L. Brain-derived neurotrophic factor blood levels after electroconvulsive therapy in patients with major depressive disorder: A systematic review and meta-analysis. Asian journal of psychiatry. vol 51. 2021-05-27. PMID:32146142. |
our findings suggest that bdnf levels may increase after ect and may possibly be used as an indicator of treatment response after one or more weeks of ect in patients with depression. |
2021-05-27 |
2023-08-13 |
Not clear |
| Hasan Aksoy, Tülin Ergun, Mustafa Akkiprik, İrem Peker Eyuboglu, Dilek Seckin Gencosmanoglu, Gülru Pemra Cöbek Ünalan, Hakan Yöne. The impact of antipsoriatic treatment on serum pro-BDNF, BDNF levels, depression, anxiety scores, and quality of life. Dermatologic therapy. vol 34. issue 2. 2021-05-25. PMID:33580990. |
peripheral brain-derived neurotrophic factor (bdnf) and its precursor, pro-bdnf have been shown to be altered in depression. |
2021-05-25 |
2023-08-13 |
Not clear |
| Hasan Aksoy, Tülin Ergun, Mustafa Akkiprik, İrem Peker Eyuboglu, Dilek Seckin Gencosmanoglu, Gülru Pemra Cöbek Ünalan, Hakan Yöne. The impact of antipsoriatic treatment on serum pro-BDNF, BDNF levels, depression, anxiety scores, and quality of life. Dermatologic therapy. vol 34. issue 2. 2021-05-25. PMID:33580990. |
at baseline, all groups completed beck depression inventory (bdi), spielberger state-trait anxiety inventory-ii (stai-ii) and dlqi; serum bdnf, probdnf levels were measured. |
2021-05-25 |
2023-08-13 |
Not clear |
| Hasan Aksoy, Tülin Ergun, Mustafa Akkiprik, İrem Peker Eyuboglu, Dilek Seckin Gencosmanoglu, Gülru Pemra Cöbek Ünalan, Hakan Yöne. The impact of antipsoriatic treatment on serum pro-BDNF, BDNF levels, depression, anxiety scores, and quality of life. Dermatologic therapy. vol 34. issue 2. 2021-05-25. PMID:33580990. |
depression and qol improved significantly, bdnf and anxiety scores did not change. |
2021-05-25 |
2023-08-13 |
Not clear |
| Ru Liu, Xin-Miao Wu, Xue He, Run-Zhu Wang, Xiao-Yu Yin, Feng Zhou, Mu-Huo Ji, Jin-Chun She. Contribution of DNA methyltransferases to spared nerve injury induced depression partially through epigenetically repressing Bdnf in hippocampus: Reversal by ketamine. Pharmacology, biochemistry, and behavior. vol 200. 2021-05-24. PMID:33245982. |
contribution of dna methyltransferases to spared nerve injury induced depression partially through epigenetically repressing bdnf in hippocampus: reversal by ketamine. |
2021-05-24 |
2023-08-13 |
rat |
| Ru Liu, Xin-Miao Wu, Xue He, Run-Zhu Wang, Xiao-Yu Yin, Feng Zhou, Mu-Huo Ji, Jin-Chun She. Contribution of DNA methyltransferases to spared nerve injury induced depression partially through epigenetically repressing Bdnf in hippocampus: Reversal by ketamine. Pharmacology, biochemistry, and behavior. vol 200. 2021-05-24. PMID:33245982. |
methylation changes of brain-derived neurotrophic factor (bdnf) in the hippocampus are critical for neuropathic pain and depression. |
2021-05-24 |
2023-08-13 |
rat |
| Ru Liu, Xin-Miao Wu, Xue He, Run-Zhu Wang, Xiao-Yu Yin, Feng Zhou, Mu-Huo Ji, Jin-Chun She. Contribution of DNA methyltransferases to spared nerve injury induced depression partially through epigenetically repressing Bdnf in hippocampus: Reversal by ketamine. Pharmacology, biochemistry, and behavior. vol 200. 2021-05-24. PMID:33245982. |
thus, we hypothesized that dnmts are required for depression genesis, probably by repressing hippocampus bdnf gene expression in rats with neuropathic pain, which can be rescued by ketamine. |
2021-05-24 |
2023-08-13 |
rat |
| Ru Liu, Xin-Miao Wu, Xue He, Run-Zhu Wang, Xiao-Yu Yin, Feng Zhou, Mu-Huo Ji, Jin-Chun She. Contribution of DNA methyltransferases to spared nerve injury induced depression partially through epigenetically repressing Bdnf in hippocampus: Reversal by ketamine. Pharmacology, biochemistry, and behavior. vol 200. 2021-05-24. PMID:33245982. |
sni upregulated dnmts and downregulated bdnf and exon i in the hippocampus and induced depression behaviors, whereas blocking the upregulation of dnmts with rg108 alleviated sni-induced depression by up-regulation of the expression of bdnf and exon i. |
2021-05-24 |
2023-08-13 |
rat |
| Han-Xiao Zhu, Li-Jing Cheng, Ri-Wei Ou Yang, Yang-Yang Li, Jian Liu, Dan Dai, Wei Wang, Ning Yang, Yun L. Reduced Amygdala Microglial Expression of Brain-Derived Neurotrophic Factor and Tyrosine Kinase Receptor B (TrkB) in a Rat Model of Poststroke Depression. Medical science monitor : international medical journal of experimental and clinical research. vol 26. 2021-05-20. PMID:33206632. |
background previous studies have implicated reduced brain-derived neurotrophic factor (bdnf) expression and bdnf-trkb receptor signaling as well as microglial activation and neuroinflammation in poststroke depression (psd). |
2021-05-20 |
2023-08-13 |
rat |