| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Mu-Hong Chen, Chung-Feng Kao, Shih-Jen Tsai, Cheng-Ta Li, Wei-Chen Lin, Chen-Jee Hong, Ya-Mei Bai, Pei-Chi Tu, Tung-Ping S. Treatment response to low-dose ketamine infusion for treatment-resistant depression: A gene-based genome-wide association study. Genomics. vol 113. issue 2. 2021-11-15. PMID:33370585. |
evidence suggested the crucial roles of brain-derived neurotrophic factor (bdnf) and glutamate system functioning in the antidepressant mechanisms of low-dose ketamine infusion in treatment-resistant depression (trd). |
2021-11-15 |
2023-08-13 |
Not clear |
| Jennifer M Parrott, Grace A Porter, Laney Redus, Jason C O'Conno. Brain derived neurotrophic factor deficiency exacerbates inflammation-induced anhedonia in mice. Psychoneuroendocrinology. vol 134. 2021-11-15. PMID:34601342. |
brain-derived neurotrophic factor (bdnf) is implicated in the pathology of major depression and influences the inflammatory response. |
2021-11-15 |
2023-08-13 |
mouse |
| Jennifer M Parrott, Grace A Porter, Laney Redus, Jason C O'Conno. Brain derived neurotrophic factor deficiency exacerbates inflammation-induced anhedonia in mice. Psychoneuroendocrinology. vol 134. 2021-11-15. PMID:34601342. |
prolonged immune system activation can cause depression symptoms, and individuals with low bdnf expression may be vulnerable to inflammation-induced depression. |
2021-11-15 |
2023-08-13 |
mouse |
| Chen Li, Fantao Meng, Yun Lei, Jing Liu, Jing Liu, Jingyan Zhang, Fang Liu, Cuilan Liu, Ming Guo, Xin-Yun L. Leptin regulates exon-specific transcription of the Bdnf gene via epigenetic modifications mediated by an AKT/p300 HAT cascade. Molecular psychiatry. vol 26. issue 8. 2021-11-11. PMID:33106599. |
here, we show that the leptin receptor (leprb) colocalizes with brain-derived neurotrophic factor (bdnf), a key player in the pathophysiology of major depression and the action of antidepressants, in the dentate gyrus of the hippocampus. |
2021-11-11 |
2023-08-13 |
Not clear |
| Yin-Qiong Huang, Yaofeng Wang, Keyue Hu, Shu Lin, Xia-Hong Li. Hippocampal Glycerol-3-Phosphate Acyltransferases 4 and BDNF in the Progress of Obesity-Induced Depression. Frontiers in endocrinology. vol 12. 2021-11-10. PMID:34054732. |
hippocampal glycerol-3-phosphate acyltransferases 4 and bdnf in the progress of obesity-induced depression. |
2021-11-10 |
2023-08-13 |
Not clear |
| Mahtab Alam, Md Noushad Javed, Abul Kalam Najmi, Farhan Jalees Ahmad, Syed Sarim Imam, Mohd Akhta. Thymoquinone lipid nanoparticles cut the Gordian knots of depression via neuroprotective BDNF and downregulation of neuro-inflammatory NF-κB, IL-6, and TNF-α in LPS treated rats. Current drug metabolism. 2021-11-09. PMID:34749619. |
thymoquinone lipid nanoparticles cut the gordian knots of depression via neuroprotective bdnf and downregulation of neuro-inflammatory nf-κb, il-6, and tnf-α in lps treated rats. |
2021-11-09 |
2023-08-13 |
rat |
| Y Li, X Feng, H Ren, H Huang, Yu Wang, S Y. Low-Dose Ozone Therapy Improves Sleep Quality in Patients with Insomnia and Coronary Heart Disease by Elevating Serum BDNF and GABA. Bulletin of experimental biology and medicine. vol 170. issue 4. 2021-11-04. PMID:33713235. |
the 3-month course of low-dose ozone therapy significantly elevated serum bdnf and gaba in chd patients with insomnia and improved parameters of anxiety, depression, and sleep quality according to hospital anxiety and depression scale (hads), pittsburgh sleep quality index (psqi), and self-rating scale of sleep (srss). |
2021-11-04 |
2023-08-13 |
Not clear |
| Marion Trousselard, Damien Claverie, Dominique Fromage, Christel Becker, Jean-Guillaume Houël, Jean-Jacques Benoliel, Frédéric Canin. The Relationship between Allostasis and Mental Health Patterns in a Pre-Deployment French Military Cohort. European journal of investigation in health, psychology and education. vol 11. issue 4. 2021-10-29. PMID:34698145. |
(2) methods: a cohort of 290 soldiers was evaluated in a cross-sectional study with respect to psychopathology (ptsd, anxiety, depression), psychological functioning (stress reactivity, psychological suffering), and allostatic profile (urinary cortisol and 8-iso-pgf2α, blood cortisol and bdnf). |
2021-10-29 |
2023-08-13 |
Not clear |
| Emanuela Bianciardi, Ylenia Barone, Valentina Lo Serro, Alberto De Stefano, Nicoletta Giacchetti, Franca Aceti, Cinzia Niol. Inflammatory markers of perinatal depression in women with and without history of trauma. Rivista di psichiatria. vol 56. issue 5. 2021-10-28. PMID:34663990. |
in this study, we explored the possible association of inflammatory markers with perinatal depression (pnd), measuring serum levels of cytokines (il-6, tnf-a, ifn-γ), acute phase proteins (crp), erythrocyte sedimentation rate (esr), cortisol and brain-derived neurotrophic factor (bdnf) in women at the second trimester of pregnancy. |
2021-10-28 |
2023-08-13 |
Not clear |
| Heidrun Lioba Wunram, Max Oberste, Alischa Ziemendorff, Stefanie Hamacher, Tugba Kapanci, Raoul Heller, Serjosha Blick, Wilhelm Bloch, Theresia Christina Clajus, Eckhard Schönau, Stephan Bender, Oliver Frick. Differential effects of ergometer-cycling and Whole-Body-Vibration training on serological BDNF and IGF-1 in the treatment of adolescent depression - is there an impact of BDNFp.Val66Met variants? Physiology & behavior. vol 241. 2021-10-27. PMID:34536433. |
differential effects of ergometer-cycling and whole-body-vibration training on serological bdnf and igf-1 in the treatment of adolescent depression - is there an impact of bdnfp.val66met variants? |
2021-10-27 |
2023-08-13 |
Not clear |
| Heidrun Lioba Wunram, Max Oberste, Alischa Ziemendorff, Stefanie Hamacher, Tugba Kapanci, Raoul Heller, Serjosha Blick, Wilhelm Bloch, Theresia Christina Clajus, Eckhard Schönau, Stephan Bender, Oliver Frick. Differential effects of ergometer-cycling and Whole-Body-Vibration training on serological BDNF and IGF-1 in the treatment of adolescent depression - is there an impact of BDNFp.Val66Met variants? Physiology & behavior. vol 241. 2021-10-27. PMID:34536433. |
pathogenesis and treatment of adolescent depression may be influenced by growth-factors, including brain-derived neurotrophic factor (bdnf) and insulin-like growth factor 1 (igf-1). |
2021-10-27 |
2023-08-13 |
Not clear |
| Hang Xu, Jiesi Wang, Haiyang Jing, Bart Ellenbroek, Feng Shao, Weiwen Wan. mPFC GABAergic transmission mediated the role of BDNF signaling in cognitive impairment but not anxiety induced by adolescent social stress. Neuropharmacology. vol 184. 2021-10-22. PMID:33245959. |
these results suggest that the downstream gabaergic transmission of bdnf signaling in the mpfc involved in depression with comorbid cognitive dysfunction induced by ass and can be used as a therapeutic target for the treatment of cognitive dysfunction in depression. |
2021-10-22 |
2023-08-13 |
mouse |
| Asia Afzal, Zehra Batool, Sadia Sadir, Laraib Liaquat, Sidrah Shahzad, Saiqa Tabassum, Saara Ahmad, Noor Kamil, Tahira Perveen, Saida Haide. Therapeutic Potential of Curcumin in Reversing the Depression and Associated Pseudodementia via Modulating Stress Hormone, Hippocampal Neurotransmitters, and BDNF Levels in Rats. Neurochemical research. vol 46. issue 12. 2021-10-21. PMID:34409523. |
therapeutic potential of curcumin in reversing the depression and associated pseudodementia via modulating stress hormone, hippocampal neurotransmitters, and bdnf levels in rats. |
2021-10-21 |
2023-08-13 |
rat |
| Shirin Sadighparvar, Saber Ghazizadeh Darband, Bahman Yousefi, Mojtaba Kaviani, Firouz Ghaderi-Pakdel, Ainaz Mihanfar, Ghader Babaei, Kazhal Mobaraki, Maryam Majidini. Combination of quercetin and exercise training attenuates depression in rats with 1,2-dimethylhydrazine-induced colorectal cancer: Possible involvement of inflammation and BDNF signalling. Experimental physiology. vol 105. issue 9. 2021-10-20. PMID:32681548. |
combination of quercetin and exercise training attenuates depression in rats with 1,2-dimethylhydrazine-induced colorectal cancer: possible involvement of inflammation and bdnf signalling. |
2021-10-20 |
2023-08-13 |
rat |
| M Kusmider, A Faron-Górecka, J Solich, P Pabian, M Dziedzicka-Wasylewsk. Time-course of changes in key catecholaminergic receptors and trophic systems in rat brain after antidepressant administration. Neurochemistry international. vol 141. 2021-10-18. PMID:33132141. |
the present study was designed to evaluate dynamic alterations in catecholaminergic receptors and calcyon (associated with monoaminergic theory of depression) in the rat brain as well as brain-derived neurotrophic factor (bdnf) and tyrosine kinase beta (trkb; related to neurotrophin theory) induced by three antidepressant drugs (ads) with various pharmacological profiles (imipramine, desipramine, and citalopram) administered for 21 days or acutely, followed by various drug-free periods. |
2021-10-18 |
2023-08-13 |
rat |
| Lin Guo, Tianyu Gao, Ce Gao, Xiaoxia Jia, Jing Ni, Chaojun Han, Yun Wan. Stimulation of astrocytic sigma-1 receptor is sufficient to ameliorate inflammation- induced depression. Behavioural brain research. vol 410. 2021-10-18. PMID:33961912. |
besides, specific stimulation of astrocytic sig-1r decreased the activation of astrocyte and microglia, as well as increased brain-derived neurotrophic factor (bdnf) in lps-induced depression. |
2021-10-18 |
2023-08-13 |
Not clear |
| Kensuke Nakajima, Shigeru Ois. Upregulating Effect of Wheat on Brain-Derived Neurotrophic Factor in Human Lung Adenocarcinoma A549 Cells. Journal of oleo science. vol 70. issue 6. 2021-10-15. PMID:33967169. |
peripheral bdnf can traverse the blood-brain barrier and reach the hippocampus; accordingly, substances that upregulate bdnf production in peripheral tissues may be useful in the treatment of depression. |
2021-10-15 |
2023-08-13 |
human |
| Zhijun Jiang, Zemeng Zhu, Mingyue Zhao, Wei Wang, Haonan Li, Dexiang Liu, Fang Pa. H3K9me2 regulation of BDNF expression in the hippocampus and medial prefrontal cortex is involved in the depressive-like phenotype induced by maternal separation in male rats. Psychopharmacology. vol 238. issue 10. 2021-10-15. PMID:34328517. |
brain-derived neurotrophic factor (bdnf) has been confirmed to be involved in the pathophysiology of depression. |
2021-10-15 |
2023-08-13 |
rat |
| Zhijun Jiang, Zemeng Zhu, Mingyue Zhao, Wei Wang, Haonan Li, Dexiang Liu, Fang Pa. H3K9me2 regulation of BDNF expression in the hippocampus and medial prefrontal cortex is involved in the depressive-like phenotype induced by maternal separation in male rats. Psychopharmacology. vol 238. issue 10. 2021-10-15. PMID:34328517. |
however, the mechanism by which els alters the epigenetic regulation of bdnf and changes susceptibility to depression has not been fully clarified. |
2021-10-15 |
2023-08-13 |
rat |
| Wenbo Xu, Xiaoxiao Yao, Fangyi Zhao, Haisheng Zhao, Ziqian Cheng, Wei Yang, Ranji Cui, Songbai Xu, Bingjin L. Changes in Hippocampal Plasticity in Depression and Therapeutic Approaches Influencing These Changes. Neural plasticity. vol 2020. 2021-10-14. PMID:33293948. |
at present, the brain-derived neurotrophic factor (bdnf) and neurogenesis hypotheses have highlighted the important role of plasticity in depression. |
2021-10-14 |
2023-08-13 |
human |