Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
Tamara Shiner, Anat Mirelman, Yevgenia Rosenblum, Gitit Kavé, Mali Gana Weisz, Anat Bar-Shira, Orly Goldstein, Avner Thaler, Tanya Gurevich, Avi Orr-Urtreger, Nir Giladi, Noa Bregma. The Effect of GBA Mutations and APOE Polymorphisms on Dementia with Lewy Bodies in Ashkenazi Jews. Journal of Alzheimer's disease : JAD. vol 80. issue 3. 2021-09-14. PMID:33646158. |
glucocerebrosidase (gba) gene mutations and apoe polymorphisms are common in dementia with lewy bodies (dlb), however their clinical impact is only partially elucidated. |
2021-09-14 |
2023-08-13 |
Not clear |
Pinar Soysal, Semen Gokce Ta. The prevalence and co-incidence of geriatric syndromes in older patients with early-stage Alzheimer's disease and dementia with Lewy bodies. Aging clinical and experimental research. vol 33. issue 9. 2021-09-13. PMID:33506311. |
this study was aimed to compare early-stage alzheimer's disease (ad) and dementia with lewy bodies (dlb), the two most common types of dementia in the elderly, in terms of the prevalence of geriatric syndromes. |
2021-09-13 |
2023-08-13 |
Not clear |
Pinar Soysal, Semen Gokce Ta. The prevalence and co-incidence of geriatric syndromes in older patients with early-stage Alzheimer's disease and dementia with Lewy bodies. Aging clinical and experimental research. vol 33. issue 9. 2021-09-13. PMID:33506311. |
patients with early-stage dementia with dlb and ad were included, and were questioned in terms of geriatric syndromes including polypharmacy, malnutrition, frailty, sarcopenia, dynapenia, orthostatic hypotension (oh), urinary and fecal incontinence, falls, fear of falling (fof), depression, insomnia, excessive daytime sleepiness, pressure ulcers. |
2021-09-13 |
2023-08-13 |
Not clear |
Mami Takemoto, Toru Yamashita, Yasuyuki Ohta, Koh Tadokoro, Yoshio Omote, Ryuta Morihara, Koji Ab. Cerebral Microbleeds in Patients with Parkinson's Disease and Dementia with Lewy Bodies: Comparison Using Magnetic Resonance Imaging and 99 mTc-ECD SPECT Subtraction Imaging. Journal of Alzheimer's disease : JAD. vol 80. issue 1. 2021-09-13. PMID:33523013. |
cerebral microbleeds (cmbs) in patients with parkinson's disease (pd) or dementia with lewy bodies (dlb) have not been adequately studied. |
2021-09-13 |
2023-08-13 |
Not clear |
Taylor Rigby, David K Johnson, Angela Taylor, James E Galvi. Comparison of the Caregiving Experience of Grief, Burden, and Quality of Life in Dementia with Lewy Bodies, Alzheimer's Disease, and Parkinson's Disease Dementia. Journal of Alzheimer's disease : JAD. vol 80. issue 1. 2021-09-13. PMID:33554912. |
caregivers of persons living with alzheimer's disease (ad), dementia with lewy bodies (dlb), and parkinson's disease dementia (pdd) are faced with numerous challenges. |
2021-09-13 |
2023-08-13 |
Not clear |
Kejal Kantarci, Bradley F Boeve, Scott A Przybelski, Timothy G Lesnick, Qin Chen, Julie Fields, Christopher G Schwarz, Matthew L Senjem, Jeffrey L Gunte, Clifford R Jack, Paul Min, Manoj Jain, Toji Miyagawa, Rodolfo Savica, Jonathan Graff-Radford, Hugo Botha, David T Jones, David S Knopman, Neill Graff-Radford, Tanis J Ferman, Ronald C Petersen, Val J Low. FDG PET metabolic signatures distinguishing prodromal DLB and prodromal AD. NeuroImage. Clinical. vol 31. 2021-09-13. PMID:34252877. |
patients with dementia with lewy bodies (dlb) are characterized by hypometabolism in the parieto-occipital cortex and the cingulate island sign (cis) on |
2021-09-13 |
2023-08-13 |
Not clear |
Yuichi Inoue, Taeko Sasai, Koichi Hirat. Electroencephalographic Finding in Idiopathic REM Sleep Behavior Disorder. Neuropsychobiology. vol 71. issue 1. 2021-09-13. PMID:25766757. |
several longitudinal studies have revealed that a high proportion of irbd patients convert to α-synucleinopathies such as parkinson's disease and dementia with lewy body disease (dlb). |
2021-09-13 |
2023-08-13 |
Not clear |
Daniela Enache, Joana B Pereira, Vesna Jelic, Bengt Winblad, Per Nilsson, Dag Aarsland, Erika Bereczk. Increased Cerebrospinal Fluid Concentration of ZnT3 Is Associated with Cognitive Impairment in Alzheimer's Disease. Journal of Alzheimer's disease : JAD. vol 77. issue 3. 2021-09-09. PMID:32925049. |
cognitive deficits arising in the course of alzheimer's disease (ad), dementia with lewy bodies (dlb), and parkinson's disease with dementia (pdd) are directly linked to synaptic loss. |
2021-09-09 |
2023-08-13 |
Not clear |
Rahel Feleke, Regina H Reynolds, Amy M Smith, Bension Tilley, Sarah A Gagliano Taliun, John Hardy, Paul M Matthews, Steve Gentleman, David R Owen, Michael R Johnson, Prashant K Srivastava, Mina Ryte. Cross-platform transcriptional profiling identifies common and distinct molecular pathologies in Lewy body diseases. Acta neuropathologica. vol 142. issue 3. 2021-09-09. PMID:34309761. |
parkinson's disease (pd), parkinson's disease with dementia (pdd) and dementia with lewy bodies (dlb) are three clinically, genetically and neuropathologically overlapping neurodegenerative diseases collectively known as the lewy body diseases (lbds). |
2021-09-09 |
2023-08-13 |
Not clear |
Ahmet T Isik, Esra Ates Bulut, Ozge Dokuzlar, Derya Kaya, Neziha Erken, Fatma S Dost Gunay, Mehmet S Onta. Cardiac and Blood Pressure Safety of Transdermal Rivastigmine in Elderly Patients With Dementia With Lewy Bodies. Alzheimer disease and associated disorders. vol 34. issue 4. 2021-09-08. PMID:32809983. |
dementia with lewy bodies (dlb) is the second most common dementia. |
2021-09-08 |
2023-08-13 |
Not clear |
Clark Funnell, Howard H Feldman, Ian R A Mackenzie, Mari L DeMarc. Applying the Alzheimer Disease ATN Diagnostic Framework in Atypical Dementia. Alzheimer disease and associated disorders. vol 34. issue 4. 2021-09-08. PMID:33215886. |
recently, an at(n) csf profile has been described for dementia with lewy bodies (dlb), a disorder which is difficult to distinguish clinically from ad, particularly early in the disease course. |
2021-09-08 |
2023-08-13 |
Not clear |
Luca Beretta, Giulia Carli, Paolo Caffarra, Daniela Peran. Distinct brain dysfunctions underlying visuo-constructive deficit in DLB and AD. Brain imaging and behavior. 2021-09-07. PMID:34490534. |
in this study we examined the neuroanatomical substrates of rocf-c performance in patients with dementia with lewy bodies (dlb) and patients with alzheimer's disease (ad). |
2021-09-07 |
2023-08-13 |
Not clear |
Hirofumi Sato, Shutaro Nakaaki, Junko Sato, Ryo Shikimoto, Toshi A Furukawa, Masaru Mimura, Tatsuo Akech. Caregiver self-efficacy and associated factors among caregivers of patients with dementia with Lewy bodies and caregivers of patients with Alzheimer's disease. Psychogeriatrics : the official journal of the Japanese Psychogeriatric Society. vol 21. issue 5. 2021-09-06. PMID:34216184. |
dementia with lewy bodies (dlb) is characterized by neuropsychiatric symptoms, which can be distressing to caregivers. |
2021-09-06 |
2023-08-13 |
Not clear |
Che-Sheng Chu, Fu-Chi Yang, Ping-Tao Tseng, Brendon Stubbs, Aarsland Dag, Andre F Carvalho, Trevor Thompson, Yu-Kang Tu, Ta-Chuan Yeh, Dian-Jeng Li, Chia-Kuang Tsai, Tien-Yu Chen, Manabu Ikeda, Chih-Sung Liang, Kuan-Pin S. Treatment Efficacy and Acceptabilityof Pharmacotherapies for Dementia with Lewy Bodies: A Systematic Review and Network Meta-Analysis. Archives of gerontology and geriatrics. vol 96. 2021-09-06. PMID:34256210. |
we investigated the efficacy and acceptability of pharmacotherapy for dementia with lewy bodies (dlb) while simultaneously considering the neuropsychiatric symptoms (nps), cognitive function, motor symptoms, and acceptability. |
2021-09-06 |
2023-08-13 |
Not clear |
David J Koss, Odeta Bondarevaite, Sara Adams, Marta Leite, Flaviano Giorgini, Johannes Attems, Tiago F Outeir. RAB39B is redistributed in dementia with Lewy bodies and is sequestered within aβ plaques and Lewy bodies. Brain pathology (Zurich, Switzerland). vol 31. issue 1. 2021-09-04. PMID:32762091. |
here, analysis of the spatial distribution and expression of rab39b was conducted in post-mortem human brain tissue from cases of dementia with lewy bodies (dlb, n = 10), alzheimer's disease (ad, n = 12) and controls (n = 12). |
2021-09-04 |
2023-08-13 |
human |
Clara Y B Low, Jasinda H Lee, Frances T W Lim, Chingli Lee, Clive Ballard, Paul T Francis, Mitchell K P Lai, Michelle G K Ta. Isoform-specific upregulation of FynT kinase expression is associated with tauopathy and glial activation in Alzheimer's disease and Lewy body dementias. Brain pathology (Zurich, Switzerland). vol 31. issue 2. 2021-09-04. PMID:33128789. |
since both the aforementioned neuropathological features are also variably found in lewy body dementias (lbd), we investigated potential perturbations of fyn expression in the post-mortem neocortex of patients with ad, as well as those diagnosed as having one of the two main subgroups of lbd: parkinson's disease dementia (pdd) and dementia with lewy bodies (dlb). |
2021-09-04 |
2023-08-13 |
mouse |
Andrea Pilotto, Alberto Romagnolo, Andrea Scalvini, Mario Masellis, Yasushi Shimo, Laura Bonanni, Richard Camicioli, Lily L Wang, Alok K Dwivedi, Katherine Longardner, Federico Rodriguez-Porcel, Mark DiFrancesco, Joaquin A Vizcarra, Elisa Montanaro, Simona Maule, Alessandro Lupini, Carmen Ojeda-López, Sandra E Black, Stefano Delli Pizzi, Myrlene Gee, Ryota Tanaka, Kazuo Yamashiro, Taku Hatano, Barbara Borroni, Roberto Gasparotti, Maria C Rizzetti, Nobutaka Hattori, Leonardo Lopiano, Irene Litvan, Alberto J Espay, Alessandro Padovani, Aristide Merol. Association of Orthostatic Hypotension With Cerebral Atrophy in Patients With Lewy Body Disorders. Neurology. vol 97. issue 8. 2021-09-03. PMID:34099524. |
to evaluate whether orthostatic hypotension (oh) or supine hypertension (sh) is associated with brain atrophy and white matter hyperintensities (wmh), we analyzed clinical and radiologic data from a large multicenter consortium of patients with parkinson disease (pd) and dementia with lewy bodies (dlb). |
2021-09-03 |
2023-08-13 |
Not clear |
Fangzhou Li, Naohiro Egawa, Shusuke Yoshimoto, Haruo Mizutani, Katsuya Kobayashi, Naoko Tachibana, Ryosuke Takahash. Potential Clinical Applications and Future Prospect of Wireless and Mobile Electroencephalography on the Assessment of Cognitive Impairment. Bioelectricity. vol 1. issue 2. 2021-09-03. PMID:34471813. |
posterior eeg characteristics in dementia with lewy bodies (dlb) allowed discrimination of dlb from ad and controls with high accuracy. |
2021-09-03 |
2023-08-13 |
Not clear |
Anri Sakurai, Taiji Tsunemi, Yuta Ishiguro, Ayami Okuzumi, Taku Hatano, Nobutaka Hattor. Comorbid alpha synucleinopathies in idiopathic normal pressure hydrocephalus. Journal of neurology. 2021-09-01. PMID:34468800. |
this study aimed to determine the prevalence and clinical features of parkinson's disease (pd)/pd dementia (pd/pdd) or dementia with lewy bodies (dlb) in idiopathic normal pressure hydrocephalus (inph). |
2021-09-01 |
2023-08-13 |
Not clear |
Julia Marschallinger, Barbara Altendorfer, Edward Rockenstein, Miriam Holztrattner, Julia Garnweidner-Raith, Nadine Pillichshammer, Iris Leister, Birgit Hutter-Paier, Katharina Strempfl, Michael S Unger, Mansoor Chishty, Thomas Felder, Mary Johnson, Johannes Attems, Eliezer Masliah, Ludwig Aigne. The Leukotriene Receptor Antagonist Montelukast Reduces Alpha-Synuclein Load and Restores Memory in an Animal Model of Dementia with Lewy Bodies. Neurotherapeutics : the journal of the American Society for Experimental NeuroTherapeutics. vol 17. issue 3. 2021-09-01. PMID:32072462. |
dementia with lewy bodies (dlb) represents a huge medical need as it accounts for up to 30% of all dementia cases, and there is no cure available. |
2021-09-01 |
2023-08-13 |
mouse |