| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Che-Sheng Chu, Fu-Chi Yang, Ping-Tao Tseng, Brendon Stubbs, Aarsland Dag, Andre F Carvalho, Trevor Thompson, Yu-Kang Tu, Ta-Chuan Yeh, Dian-Jeng Li, Chia-Kuang Tsai, Tien-Yu Chen, Manabu Ikeda, Chih-Sung Liang, Kuan-Pin S. Treatment Efficacy and Acceptabilityof Pharmacotherapies for Dementia with Lewy Bodies: A Systematic Review and Network Meta-Analysis. Archives of gerontology and geriatrics. vol 96. 2021-09-06. PMID:34256210. |
we investigated the efficacy and acceptability of pharmacotherapy for dementia with lewy bodies (dlb) while simultaneously considering the neuropsychiatric symptoms (nps), cognitive function, motor symptoms, and acceptability. |
2021-09-06 |
2023-08-13 |
Not clear |
| David J Koss, Odeta Bondarevaite, Sara Adams, Marta Leite, Flaviano Giorgini, Johannes Attems, Tiago F Outeir. RAB39B is redistributed in dementia with Lewy bodies and is sequestered within aβ plaques and Lewy bodies. Brain pathology (Zurich, Switzerland). vol 31. issue 1. 2021-09-04. PMID:32762091. |
here, analysis of the spatial distribution and expression of rab39b was conducted in post-mortem human brain tissue from cases of dementia with lewy bodies (dlb, n = 10), alzheimer's disease (ad, n = 12) and controls (n = 12). |
2021-09-04 |
2023-08-13 |
human |
| Clara Y B Low, Jasinda H Lee, Frances T W Lim, Chingli Lee, Clive Ballard, Paul T Francis, Mitchell K P Lai, Michelle G K Ta. Isoform-specific upregulation of FynT kinase expression is associated with tauopathy and glial activation in Alzheimer's disease and Lewy body dementias. Brain pathology (Zurich, Switzerland). vol 31. issue 2. 2021-09-04. PMID:33128789. |
since both the aforementioned neuropathological features are also variably found in lewy body dementias (lbd), we investigated potential perturbations of fyn expression in the post-mortem neocortex of patients with ad, as well as those diagnosed as having one of the two main subgroups of lbd: parkinson's disease dementia (pdd) and dementia with lewy bodies (dlb). |
2021-09-04 |
2023-08-13 |
mouse |
| Andrea Pilotto, Alberto Romagnolo, Andrea Scalvini, Mario Masellis, Yasushi Shimo, Laura Bonanni, Richard Camicioli, Lily L Wang, Alok K Dwivedi, Katherine Longardner, Federico Rodriguez-Porcel, Mark DiFrancesco, Joaquin A Vizcarra, Elisa Montanaro, Simona Maule, Alessandro Lupini, Carmen Ojeda-López, Sandra E Black, Stefano Delli Pizzi, Myrlene Gee, Ryota Tanaka, Kazuo Yamashiro, Taku Hatano, Barbara Borroni, Roberto Gasparotti, Maria C Rizzetti, Nobutaka Hattori, Leonardo Lopiano, Irene Litvan, Alberto J Espay, Alessandro Padovani, Aristide Merol. Association of Orthostatic Hypotension With Cerebral Atrophy in Patients With Lewy Body Disorders. Neurology. vol 97. issue 8. 2021-09-03. PMID:34099524. |
to evaluate whether orthostatic hypotension (oh) or supine hypertension (sh) is associated with brain atrophy and white matter hyperintensities (wmh), we analyzed clinical and radiologic data from a large multicenter consortium of patients with parkinson disease (pd) and dementia with lewy bodies (dlb). |
2021-09-03 |
2023-08-13 |
Not clear |
| Fangzhou Li, Naohiro Egawa, Shusuke Yoshimoto, Haruo Mizutani, Katsuya Kobayashi, Naoko Tachibana, Ryosuke Takahash. Potential Clinical Applications and Future Prospect of Wireless and Mobile Electroencephalography on the Assessment of Cognitive Impairment. Bioelectricity. vol 1. issue 2. 2021-09-03. PMID:34471813. |
posterior eeg characteristics in dementia with lewy bodies (dlb) allowed discrimination of dlb from ad and controls with high accuracy. |
2021-09-03 |
2023-08-13 |
Not clear |
| Anri Sakurai, Taiji Tsunemi, Yuta Ishiguro, Ayami Okuzumi, Taku Hatano, Nobutaka Hattor. Comorbid alpha synucleinopathies in idiopathic normal pressure hydrocephalus. Journal of neurology. 2021-09-01. PMID:34468800. |
this study aimed to determine the prevalence and clinical features of parkinson's disease (pd)/pd dementia (pd/pdd) or dementia with lewy bodies (dlb) in idiopathic normal pressure hydrocephalus (inph). |
2021-09-01 |
2023-08-13 |
Not clear |
| Julia Marschallinger, Barbara Altendorfer, Edward Rockenstein, Miriam Holztrattner, Julia Garnweidner-Raith, Nadine Pillichshammer, Iris Leister, Birgit Hutter-Paier, Katharina Strempfl, Michael S Unger, Mansoor Chishty, Thomas Felder, Mary Johnson, Johannes Attems, Eliezer Masliah, Ludwig Aigne. The Leukotriene Receptor Antagonist Montelukast Reduces Alpha-Synuclein Load and Restores Memory in an Animal Model of Dementia with Lewy Bodies. Neurotherapeutics : the journal of the American Society for Experimental NeuroTherapeutics. vol 17. issue 3. 2021-09-01. PMID:32072462. |
dementia with lewy bodies (dlb) represents a huge medical need as it accounts for up to 30% of all dementia cases, and there is no cure available. |
2021-09-01 |
2023-08-13 |
mouse |
| Saswata Roy, Dipanjan Banerjee, Indrajit Chatterjee, Deepika Natarajan, Christopher Joy Mathe. The Role of 18F-Flortaucipir (AV-1451) in the Diagnosis of Neurodegenerative Disorders. Cureus. vol 13. issue 7. 2021-08-31. PMID:34458044. |
the scope of discussion included the role of 18f-av-1451 positron emission tomography (pet) to aid in the diagnosis of alzheimer's disease (ad), frontotemporal dementia (ftd), dementia with lewy bodies (dlb), and parkinson's disease with dementia (pdd). |
2021-08-31 |
2023-08-13 |
Not clear |
| Chiara Giuseppina Bonomi, Vincenzo De Lucia, Alfredo Paolo Mascolo, Martina Assogna, Caterina Motta, Eugenia Scaricamazza, Fabrizio Sallustio, Nicola Biagio Mercuri, Giacomo Koch, Alessandro Martoran. Brain energy metabolism and neurodegeneration: hints from CSF lactate levels in dementias. Neurobiology of aging. vol 105. 2021-08-27. PMID:34171631. |
holding cerebrospinal fluid (csf) lactates as an indirect measure of brain metabolic activity, we first compared csf lactate levels from patients with alzheimer's disease (ad)-stratified according to the atn system and epsilon genotype-frontotemporal dementia (ftd) and dementia with lewy body (dlb) to findings from healthy controls. |
2021-08-27 |
2023-08-13 |
Not clear |
| Anastasia Bouge. Synuclein in neurodegeneration. Advances in clinical chemistry. vol 103. 2021-08-24. PMID:34229853. |
these include parkinson's disease (pd), dementia with lewy bodies (dlb), rapid eye movement sleep behavior disorder (rbd) and pure autonomic failure (paf), i.e., collectively termed α-synucleinopathies. |
2021-08-24 |
2023-08-13 |
Not clear |
| Toshinari Odawara, Kazuko Hasegawa, Ritsuko Kajiwara, Hisao Takeuchi, Masaaki Tagawa, Kenji Kosaka, Miho Murat. Long-Term Efficacy and Safety of Zonisamide for Treatment of Parkinsonism in Patients With Dementia With Lewy Bodies: An Open-Label Extension of a Phase three Randomized Controlled Trial. The American journal of geriatric psychiatry : official journal of the American Association for Geriatric Psychiatry. 2021-08-23. PMID:34420834. |
to evaluate the long-term efficacy and safety of zonisamide, an antiepileptic agent, in dementia with lewy bodies (dlb). |
2021-08-23 |
2023-08-13 |
Not clear |
| Bin Jiao, Hui Liu, Lina Guo, Xuewen Xiao, Xinxin Liao, Yafang Zhou, Ling Weng, Lu Zhou, Xin Wang, Yaling Jiang, Qijie Yang, Yuan Zhu, Lin Zhou, Weiwei Zhang, Junling Wang, Xinxiang Yan, Jinchen Li, Beisha Tang, Lu She. The role of genetics in neurodegenerative dementia: a large cohort study in South China. NPJ genomic medicine. vol 6. issue 1. 2021-08-20. PMID:34389718. |
here, 1795 patients with neurodegenerative dementias from south china were enrolled, including 1592 with alzheimer's disease (ad), 110 with frontotemporal dementia (ftd), and 93 with dementia with lewy bodies (dlb). |
2021-08-20 |
2023-08-13 |
Not clear |
| Stephen Joza, Richard Camicioli, Fang B. Falls in Synucleinopathies. The Canadian journal of neurological sciences. Le journal canadien des sciences neurologiques. vol 47. issue 1. 2021-08-20. PMID:31452470. |
parkinson's disease (pd) and other synucleinopathies, namely dementia with lewy bodies (dlb) and multiple system atrophy (msa), are common degenerative neurological disorders that share synuclein pathology. |
2021-08-20 |
2023-08-13 |
Not clear |
| Anto P Rajkumar, Abdul Hye, Johannes Lange, Yazmin Rashid Manesh, Clive Ballard, Tormod Fladby, Dag Aarslan. Next-Generation RNA-Sequencing of Serum Small Extracellular Vesicles Discovers Potential Diagnostic Biomarkers for Dementia With Lewy Bodies. The American journal of geriatric psychiatry : official journal of the American Association for Geriatric Psychiatry. vol 29. issue 6. 2021-08-18. PMID:33160816. |
there is an urgent clinical need for identifying blood-based diagnostic biomarkers for dementia with lewy bodies (dlb). |
2021-08-18 |
2023-08-13 |
human |
| Chih-Lin Chen, Min-Hsien Hsu, Chao-Hsien Hung, Pai-Yi Chiu, Chung-Hsiang Li. Prevalence and Associated Factors of Visual Hallucinations in Patients with Vascular Cognitive Impairment. Behavioural neurology. vol 2021. 2021-08-18. PMID:33505534. |
visual hallucinations (vhs) are striking features for dementia, especially dementia with lewy bodies (dlb). |
2021-08-18 |
2023-08-13 |
Not clear |
| Jung-Youn Han, Chaewon Shin, Young Pyo Cho. Preclinical Detection of Alpha-Synuclein Seeding Activity in the Colon of a Transgenic Mouse Model of Synucleinopathy by RT-QuIC. Viruses. vol 13. issue 5. 2021-08-18. PMID:33926043. |
in synucleinopathies such as parkinson's disease (pd) and dementia with lewy body (dlb), pathological alpha-synuclein (α-syn) aggregates are found in the gastrointestinal (gi) tract as well as in the brain. |
2021-08-18 |
2023-08-13 |
mouse |
| Prabesh Kanel, Martijn L T M Müller, Sygrid van der Zee, Carlos A Sanchez-Catasus, Robert A Koeppe, Kirk A Frey, Nicolaas I Bohne. Topography of Cholinergic Changes in Dementia With Lewy Bodies and Key Neural Network Hubs. The Journal of neuropsychiatry and clinical neurosciences. vol 32. issue 4. 2021-08-16. PMID:32498602. |
the authors investigated the topography of cholinergic vulnerability in patients with dementia with lewy bodies (dlb) using positron emission tomography (pet) imaging with the vesicular acetylcholine transporter (vacht) [ |
2021-08-16 |
2023-08-13 |
Not clear |
| Bhavana Patel, David J Irwin, Daniel Kaufer, Bradley F Boeve, Angela Taylor, Melissa J Armstron. Outcome Measures for Dementia With Lewy Body Clinical Trials: A Review. Alzheimer disease and associated disorders. 2021-08-16. PMID:34393189. |
dementia with lewy bodies (dlb) is one of the most common degenerative dementias. |
2021-08-16 |
2023-08-13 |
Not clear |
| Ashwini Oswal, James Gratwicke, Harith Akram, Marjan Jahanshahi, Laszlo Zaborszky, Peter Brown, Marwan Hariz, Ludvic Zrinzo, Tom Foltynie, Vladimir Litva. Cortical connectivity of the nucleus basalis of Meynert in Parkinson's disease and Lewy body dementias. Brain : a journal of neurology. vol 144. issue 3. 2021-08-13. PMID:33521808. |
parkinson's disease dementia (pdd) and dementia with lewy bodies (dlb) are related conditions that are associated with cholinergic system dysfunction. |
2021-08-13 |
2023-08-13 |
Not clear |
| Kathryn A Wyman-Chick, Lauren R O'Keefe, Daniel Weintraub, Melissa J Armstrong, Michael Rosenbloom, Phillip K Martin, Terry R Barclay, Matthew J Barret. Prodromal Dementia With Lewy Bodies: Evolution of Symptoms and Predictors of Dementia Onset. Journal of geriatric psychiatry and neurology. 2021-08-13. PMID:34114509. |
research criteria for prodromal dementia with lewy bodies (dlb) were published in 2020, but little is known regarding prodromal dlb in clinical settings. |
2021-08-13 |
2023-08-13 |
Not clear |