| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Ilaria Poggiolini, Daniel Erskine, Nishant N Vaikath, Janarthanan Ponraj, Said Mansour, Christopher M Morris, Omar M A El-Agna. RT-QuIC Using C-Terminally Truncated α-Synuclein Forms Detects Differences in Seeding Propensity of Different Brain Regions from Synucleinopathies. Biomolecules. vol 11. issue 6. 2021-09-23. PMID:34072869. |
aggregated α-synuclein (αsyn) protein is a core pathological feature of parkinson's disease (pd) and dementia with lewy bodies (dlb). |
2021-09-23 |
2023-08-13 |
Not clear |
| Stefania Pezzoli, Annachiara Cagnin, Cinzia Bussè, Giovanni Zorzi, Federica Fragiacomo, Oliver Bandmann, Annalena Venner. Cognitive correlates and baseline predictors of future development of visual hallucinations in dementia with Lewy bodies. Cortex; a journal devoted to the study of the nervous system and behavior. vol 142. 2021-09-21. PMID:34217015. |
visual hallucinations (vh) are common in dementia with lewy bodies (dlb), and are among the core symptoms for its clinical diagnosis. |
2021-09-21 |
2023-08-13 |
Not clear |
| Fabrizia D'Antonio, Joseph P M Kane, Agustin Ibañez, Simon J G Lewis, Richard Camicioli, Huali Wang, Yueyi Yu, Jing Zhang, Yong Ji, Miguel Germán Borda, Rukmini Mridula Kandadai, Claudio Babiloni, Laura Bonanni, Manabu Ikeda, Bradley F Boeve, James B Leverenz, Dag Aarslan. Dementia with Lewy bodies research consortia: A global perspective from the ISTAART Lewy Body Dementias Professional Interest Area working group. Alzheimer's & dementia (Amsterdam, Netherlands). vol 13. issue 1. 2021-09-21. PMID:34541289. |
dementia with lewy bodies (dlb) research has seen a significant growth in international collaboration over the last three decades. |
2021-09-21 |
2023-08-13 |
Not clear |
| Elie Matar, Simon R White, John-Paul Taylor, Alan Thomas, Ian G McKeith, Joseph P M Kane, Ajenthan Surendranathan, Glenda M Halliday, Simon J G Lewis, John T O'Brie. Progression of Clinical Features in Lewy Body Dementia Can Be Detected Over 6 Months. Neurology. vol 97. issue 10. 2021-09-20. PMID:34404743. |
this study aimed to quantify the trajectory and magnitude of change of the key clinical features and corresponding symptom domains of dementia with lewy bodies (dlb) and parkinson disease dementia (pdd), including global cognition, parkinsonism, recurrent visual hallucinations, cognitive fluctuations, and sleep disturbance. |
2021-09-20 |
2023-08-13 |
Not clear |
| Tomohiro Umeda, Yukari Hatanaka, Ayumi Sakai, Takami Tomiyam. Nasal Rifampicin Improves Cognition in a Mouse Model of Dementia with Lewy Bodies by Reducing α-Synuclein Oligomers. International journal of molecular sciences. vol 22. issue 16. 2021-09-20. PMID:34445158. |
α-synuclein oligomers are thought to play an important role in the pathogenesis of dementia with lewy bodies (dlb). |
2021-09-20 |
2023-08-13 |
mouse |
| Ramtin Mehraram, Marcus Kaiser, Ruth Cromarty, Sara Graziadio, John T O'Brien, Alison Killen, John-Paul Taylor, Luis R Peraz. Weighted network measures reveal differences between dementia types: An EEG study. Human brain mapping. vol 41. issue 6. 2021-09-16. PMID:31816147. |
the diagnosis of dementia with lewy bodies (dlb) versus alzheimer's disease (ad) can be difficult especially early in the disease process. |
2021-09-16 |
2023-08-13 |
Not clear |
| Ramtin Mehraram, Marcus Kaiser, Ruth Cromarty, Sara Graziadio, John T O'Brien, Alison Killen, John-Paul Taylor, Luis R Peraz. Weighted network measures reveal differences between dementia types: An EEG study. Human brain mapping. vol 41. issue 6. 2021-09-16. PMID:31816147. |
however, similar studies in lewy body diseases, that is, dlb and parkinson's disease dementia (pdd) are still lacking. |
2021-09-16 |
2023-08-13 |
Not clear |
| Ramtin Mehraram, Marcus Kaiser, Ruth Cromarty, Sara Graziadio, John T O'Brien, Alison Killen, John-Paul Taylor, Luis R Peraz. Weighted network measures reveal differences between dementia types: An EEG study. Human brain mapping. vol 41. issue 6. 2021-09-16. PMID:31816147. |
our results indicate that dementia groups present with reduced connectivity in the eeg α band, whereas dlb shows weaker posterior-anterior patterns within the β-band and greater network segregation within the θ-band compared with ad. |
2021-09-16 |
2023-08-13 |
Not clear |
| Sarah M Brooker, Dimitri Krain. Glucocerebrosidase dysfunction in neurodegenerative disease. Essays in biochemistry. 2021-09-16. PMID:34528667. |
the gba1 gene, which encodes the lysosomal hydrolase β-glucocerebrosidase (gcase) is the most common genetic risk factor for pd and is also linked to other neurodegenerative disorders including dementia with lewy bodies (dlb). |
2021-09-16 |
2023-08-13 |
Not clear |
| Kazuko Hasegawa, Kenji Kochi, Hidenori Maruyama, Osamu Konishi, Shunji Toya, Toshinari Odawar. Efficacy and Safety of Zonisamide in Dementia with Lewy Bodies Patients with Parkinsonism: A Post Hoc Analysis of Two Randomized, Double-Blind, Placebo-Controlled Trials. Journal of Alzheimer's disease : JAD. vol 79. issue 2. 2021-09-15. PMID:33337365. |
although previous phase ii and iii clinical trials conducted in japan showed that zonisamide improved parkinsonism in patients with dementia with lewy bodies (dlb), some differences in efficacy outcomes were observed between the trials. |
2021-09-15 |
2023-08-13 |
Not clear |
| Andrea Pilotto, Alberto Imarisio, Claudia Carrarini, Mirella Russo, Stefano Masciocchi, Stefano Gipponi, Elisabetta Cottini, Dag Aarsland, Henrik Zetterberg, Nicholas J Ashton, Abdul Hye, Laura Bonanni, Alessandro Padovan. Plasma Neurofilament Light Chain Predicts Cognitive Progression in Prodromal and Clinical Dementia with Lewy Bodies. Journal of Alzheimer's disease : JAD. vol 82. issue 3. 2021-09-15. PMID:34151807. |
plasma neurofilament light chain (nfl) is a marker of neuronal damage in different neurological disorders and might predict disease progression in dementia with lewy bodies (dlb). |
2021-09-15 |
2023-08-13 |
Not clear |
| Tamara Shiner, Anat Mirelman, Yevgenia Rosenblum, Gitit Kavé, Mali Gana Weisz, Anat Bar-Shira, Orly Goldstein, Avner Thaler, Tanya Gurevich, Avi Orr-Urtreger, Nir Giladi, Noa Bregma. The Effect of GBA Mutations and APOE Polymorphisms on Dementia with Lewy Bodies in Ashkenazi Jews. Journal of Alzheimer's disease : JAD. vol 80. issue 3. 2021-09-14. PMID:33646158. |
glucocerebrosidase (gba) gene mutations and apoe polymorphisms are common in dementia with lewy bodies (dlb), however their clinical impact is only partially elucidated. |
2021-09-14 |
2023-08-13 |
Not clear |
| Yuichi Inoue, Taeko Sasai, Koichi Hirat. Electroencephalographic Finding in Idiopathic REM Sleep Behavior Disorder. Neuropsychobiology. vol 71. issue 1. 2021-09-13. PMID:25766757. |
several longitudinal studies have revealed that a high proportion of irbd patients convert to α-synucleinopathies such as parkinson's disease and dementia with lewy body disease (dlb). |
2021-09-13 |
2023-08-13 |
Not clear |
| Pinar Soysal, Semen Gokce Ta. The prevalence and co-incidence of geriatric syndromes in older patients with early-stage Alzheimer's disease and dementia with Lewy bodies. Aging clinical and experimental research. vol 33. issue 9. 2021-09-13. PMID:33506311. |
this study was aimed to compare early-stage alzheimer's disease (ad) and dementia with lewy bodies (dlb), the two most common types of dementia in the elderly, in terms of the prevalence of geriatric syndromes. |
2021-09-13 |
2023-08-13 |
Not clear |
| Pinar Soysal, Semen Gokce Ta. The prevalence and co-incidence of geriatric syndromes in older patients with early-stage Alzheimer's disease and dementia with Lewy bodies. Aging clinical and experimental research. vol 33. issue 9. 2021-09-13. PMID:33506311. |
patients with early-stage dementia with dlb and ad were included, and were questioned in terms of geriatric syndromes including polypharmacy, malnutrition, frailty, sarcopenia, dynapenia, orthostatic hypotension (oh), urinary and fecal incontinence, falls, fear of falling (fof), depression, insomnia, excessive daytime sleepiness, pressure ulcers. |
2021-09-13 |
2023-08-13 |
Not clear |
| Mami Takemoto, Toru Yamashita, Yasuyuki Ohta, Koh Tadokoro, Yoshio Omote, Ryuta Morihara, Koji Ab. Cerebral Microbleeds in Patients with Parkinson's Disease and Dementia with Lewy Bodies: Comparison Using Magnetic Resonance Imaging and 99 mTc-ECD SPECT Subtraction Imaging. Journal of Alzheimer's disease : JAD. vol 80. issue 1. 2021-09-13. PMID:33523013. |
cerebral microbleeds (cmbs) in patients with parkinson's disease (pd) or dementia with lewy bodies (dlb) have not been adequately studied. |
2021-09-13 |
2023-08-13 |
Not clear |
| Taylor Rigby, David K Johnson, Angela Taylor, James E Galvi. Comparison of the Caregiving Experience of Grief, Burden, and Quality of Life in Dementia with Lewy Bodies, Alzheimer's Disease, and Parkinson's Disease Dementia. Journal of Alzheimer's disease : JAD. vol 80. issue 1. 2021-09-13. PMID:33554912. |
caregivers of persons living with alzheimer's disease (ad), dementia with lewy bodies (dlb), and parkinson's disease dementia (pdd) are faced with numerous challenges. |
2021-09-13 |
2023-08-13 |
Not clear |
| Kejal Kantarci, Bradley F Boeve, Scott A Przybelski, Timothy G Lesnick, Qin Chen, Julie Fields, Christopher G Schwarz, Matthew L Senjem, Jeffrey L Gunte, Clifford R Jack, Paul Min, Manoj Jain, Toji Miyagawa, Rodolfo Savica, Jonathan Graff-Radford, Hugo Botha, David T Jones, David S Knopman, Neill Graff-Radford, Tanis J Ferman, Ronald C Petersen, Val J Low. FDG PET metabolic signatures distinguishing prodromal DLB and prodromal AD. NeuroImage. Clinical. vol 31. 2021-09-13. PMID:34252877. |
patients with dementia with lewy bodies (dlb) are characterized by hypometabolism in the parieto-occipital cortex and the cingulate island sign (cis) on |
2021-09-13 |
2023-08-13 |
Not clear |
| Daniela Enache, Joana B Pereira, Vesna Jelic, Bengt Winblad, Per Nilsson, Dag Aarsland, Erika Bereczk. Increased Cerebrospinal Fluid Concentration of ZnT3 Is Associated with Cognitive Impairment in Alzheimer's Disease. Journal of Alzheimer's disease : JAD. vol 77. issue 3. 2021-09-09. PMID:32925049. |
cognitive deficits arising in the course of alzheimer's disease (ad), dementia with lewy bodies (dlb), and parkinson's disease with dementia (pdd) are directly linked to synaptic loss. |
2021-09-09 |
2023-08-13 |
Not clear |
| Rahel Feleke, Regina H Reynolds, Amy M Smith, Bension Tilley, Sarah A Gagliano Taliun, John Hardy, Paul M Matthews, Steve Gentleman, David R Owen, Michael R Johnson, Prashant K Srivastava, Mina Ryte. Cross-platform transcriptional profiling identifies common and distinct molecular pathologies in Lewy body diseases. Acta neuropathologica. vol 142. issue 3. 2021-09-09. PMID:34309761. |
parkinson's disease (pd), parkinson's disease with dementia (pdd) and dementia with lewy bodies (dlb) are three clinically, genetically and neuropathologically overlapping neurodegenerative diseases collectively known as the lewy body diseases (lbds). |
2021-09-09 |
2023-08-13 |
Not clear |