| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Prabesh Kanel, Martijn L T M Müller, Sygrid van der Zee, Carlos A Sanchez-Catasus, Robert A Koeppe, Kirk A Frey, Nicolaas I Bohne. Topography of Cholinergic Changes in Dementia With Lewy Bodies and Key Neural Network Hubs. The Journal of neuropsychiatry and clinical neurosciences. vol 32. issue 4. 2021-08-16. PMID:32498602. |
the authors investigated the topography of cholinergic vulnerability in patients with dementia with lewy bodies (dlb) using positron emission tomography (pet) imaging with the vesicular acetylcholine transporter (vacht) [ |
2021-08-16 |
2023-08-13 |
Not clear |
| Bhavana Patel, David J Irwin, Daniel Kaufer, Bradley F Boeve, Angela Taylor, Melissa J Armstron. Outcome Measures for Dementia With Lewy Body Clinical Trials: A Review. Alzheimer disease and associated disorders. 2021-08-16. PMID:34393189. |
dementia with lewy bodies (dlb) is one of the most common degenerative dementias. |
2021-08-16 |
2023-08-13 |
Not clear |
| Ashwini Oswal, James Gratwicke, Harith Akram, Marjan Jahanshahi, Laszlo Zaborszky, Peter Brown, Marwan Hariz, Ludvic Zrinzo, Tom Foltynie, Vladimir Litva. Cortical connectivity of the nucleus basalis of Meynert in Parkinson's disease and Lewy body dementias. Brain : a journal of neurology. vol 144. issue 3. 2021-08-13. PMID:33521808. |
parkinson's disease dementia (pdd) and dementia with lewy bodies (dlb) are related conditions that are associated with cholinergic system dysfunction. |
2021-08-13 |
2023-08-13 |
Not clear |
| Kathryn A Wyman-Chick, Lauren R O'Keefe, Daniel Weintraub, Melissa J Armstrong, Michael Rosenbloom, Phillip K Martin, Terry R Barclay, Matthew J Barret. Prodromal Dementia With Lewy Bodies: Evolution of Symptoms and Predictors of Dementia Onset. Journal of geriatric psychiatry and neurology. 2021-08-13. PMID:34114509. |
research criteria for prodromal dementia with lewy bodies (dlb) were published in 2020, but little is known regarding prodromal dlb in clinical settings. |
2021-08-13 |
2023-08-13 |
Not clear |
| Miho Murata, Toshinari Odawara, Kazuko Hasegawa, Ritsuko Kajiwara, Hisao Takeuchi, Masaaki Tagawa, Kenji Kosak. Effect of zonisamide on parkinsonism in patients with dementia with Lewy bodies: A phase 3 randomized clinical trial. Parkinsonism & related disorders. vol 76. 2021-08-12. PMID:31982288. |
zonisamide is approved in japan for treating motor dysfunction in parkinson's disease, and might also be effective for parkinsonism in patients with dementia with lewy bodies (dlb). |
2021-08-12 |
2023-08-13 |
Not clear |
| Megumi Sato, Sayaka Miki, Ryuji Sakakibar. [Parkinson's Disease, Dementia with Lewy Bodies and Brain-Gut Interactions]. Brain and nerve = Shinkei kenkyu no shinpo. vol 73. issue 8. 2021-08-12. PMID:34376592. |
lewy body diseases (lbd)-including parkinson's disease (pd) and dementia with lewy bodies (dlb)-are associated significant gastrointestinal (gi) symptoms, particularly constipation. |
2021-08-12 |
2023-08-13 |
Not clear |
| Calum A Hamilton, Fiona E Matthews, Louise M Allan, Sally Barker, Joanna Ciafone, Paul C Donaghy, Rory Durcan, Michael J Firbank, Sarah Lawley, John T O'Brien, Gemma Roberts, John-Paul Taylor, Alan J Thoma. Utility of the pareidolia test in mild cognitive impairment with Lewy bodies and Alzheimer's disease. International journal of geriatric psychiatry. vol 36. issue 9. 2021-08-11. PMID:33772864. |
previous research has identified that dementia with lewy bodies (dlb) has abnormal pareidolic responses which are associated with severity of visual hallucinations (vh), and the pareidolia test accurately classifies dlb with vh. |
2021-08-11 |
2023-08-13 |
Not clear |
| Calum A Hamilton, Fiona E Matthews, Paul C Donaghy, John-Paul Taylor, John T O'Brien, Nicola Barnett, Kirsty Olsen, Jim Lloyd, George Petrides, Ian G McKeith, Alan J Thoma. Cognitive Decline in Mild Cognitive Impairment With Lewy Bodies or Alzheimer Disease: A Prospective Cohort Study. The American journal of geriatric psychiatry : official journal of the American Association for Geriatric Psychiatry. vol 29. issue 3. 2021-08-10. PMID:32863138. |
we explored whether the mild cognitive impairment (mci) stages of dementia with lewy bodies (dlb) and alzheimer disease (ad) differ in their cognitive profiles, and longitudinal progression. |
2021-08-10 |
2023-08-13 |
Not clear |
| Michele T H. REM sleep behavior disorder (RBD). Neurobiology of disease. vol 143. 2021-08-05. PMID:32599063. |
rbd is present in 25-58% of patients with parkinson's disease and up to 90% of those with dementia with lewy bodies (dlb) or multiple system atrophy (msa). |
2021-08-05 |
2023-08-13 |
human |
| Melissa J Armstrong, Slande Alliance, Pamela Corsentino, Angela Lunde, Angela Taylo. Informal caregiver experiences at the end-of-life of individuals living with dementia with Lewy bodies: An interview study. Dementia (London, England). 2021-08-03. PMID:34340591. |
individuals with dementia with lewy bodies (dlb) commonly die from dementia-related causes, but little is known regarding caregiver experiences during the end-of-life period in dlb. |
2021-08-03 |
2023-08-13 |
human |
| Melissa J Armstrong, Slande Alliance, Pamela Corsentino, Angela Lunde, Angela Taylo. Informal caregiver experiences at the end-of-life of individuals living with dementia with Lewy bodies: An interview study. Dementia (London, England). 2021-08-03. PMID:34340591. |
while some end-of-life experiences were consistent with those described in dementia palliative care more generally (e.g., financial stresses, poor sleep, being overwhelmed, and needing increased education and support), many dlb features specifically affected end-of-life caregiver experiences, such as the presence of delusions. |
2021-08-03 |
2023-08-13 |
human |
| Melissa J Armstrong, Slande Alliance, Pamela Corsentino, Angela Lunde, Angela Taylo. Informal caregiver experiences at the end-of-life of individuals living with dementia with Lewy bodies: An interview study. Dementia (London, England). 2021-08-03. PMID:34340591. |
more research is needed regarding drivers of quality end-of-life experiences for individuals with dlb and their families and how drivers and strategies may differ between dementias. |
2021-08-03 |
2023-08-13 |
human |
| Marcello Rossi, Niccolò Candelise, Simone Baiardi, Sabina Capellari, Giulia Giannini, Christina D Orrù, Elena Antelmi, Angela Mammana, Andrew G Hughson, Giovanna Calandra-Buonaura, Anna Ladogana, Giuseppe Plazzi, Pietro Cortelli, Byron Caughey, Piero Parch. Ultrasensitive RT-QuIC assay with high sensitivity and specificity for Lewy body-associated synucleinopathies. Acta neuropathologica. vol 140. issue 1. 2021-08-02. PMID:32342188. |
the clinical diagnosis of synucleinopathies, including parkinson's disease (pd), dementia with lewy bodies (dlb), and multiple system atrophy (msa), is challenging, especially at an early disease stage, due to the heterogeneous and often non-specific clinical manifestations. |
2021-08-02 |
2023-08-13 |
Not clear |
| Kobra Etminani, Amira Soliman, Anette Davidsson, Jose R Chang, Begoña Martínez-Sanchis, Stefan Byttner, Valle Camacho, Matteo Bauckneht, Roxana Stegeran, Marcus Ressner, Marc Agudelo-Cifuentes, Andrea Chincarini, Matthias Brendel, Axel Rominger, Rose Bruffaerts, Rik Vandenberghe, Milica G Kramberger, Maja Trost, Nicolas Nicastro, Giovanni B Frisoni, Afina W Lemstra, Bart N M van Berckel, Andrea Pilotto, Alessandro Padovani, Silvia Morbelli, Dag Aarsland, Flavio Nobili, Valentina Garibotto, Miguel Ochoa-Figuero. A 3D deep learning model to predict the diagnosis of dementia with Lewy bodies, Alzheimer's disease, and mild cognitive impairment using brain 18F-FDG PET. European journal of nuclear medicine and molecular imaging. 2021-07-30. PMID:34328531. |
the purpose of this study is to develop and validate a 3d deep learning model that predicts the final clinical diagnosis of alzheimer's disease (ad), dementia with lewy bodies (dlb), mild cognitive impairment due to alzheimer's disease (mci-ad), and cognitively normal (cn) using fluorine 18 fluorodeoxyglucose pet (18f-fdg pet) and compare model's performance to that of multiple expert nuclear medicine physicians' readers. |
2021-07-30 |
2023-08-13 |
Not clear |
| Antonio Dominguez-Meijide, Valeria Parrales, Eftychia Vasili, Florencia González-Lizárraga, Annekatrin König, Diana F Lázaro, Annie Lannuzel, Stéphane Haik, Elaine Del Bel, Rosana Chehín, Rita Raisman-Vozari, Patrick P Michel, Nicolas Bizat, Tiago Fleming Outeir. Doxycycline inhibits α-synuclein-associated pathologies in vitro and in vivo. Neurobiology of disease. vol 151. 2021-07-29. PMID:33429042. |
parkinson's disease (pd) and dementia with lewy bodies (dlb) are neurodegenerative disorders characterized by the misfolding and aggregation of alpha-synuclein (asyn). |
2021-07-29 |
2023-08-13 |
Not clear |
| Chloe A Stewart, Elizabeth C Finge. The supraoptic and paraventricular nuclei in healthy aging and neurodegeneration. Handbook of clinical neurology. vol 180. 2021-07-28. PMID:34225924. |
this chapter reviews the involvement of the son and pvn, the hypothalamic-pituitary axes, and the peptide hormones produced in both nuclei in healthy aging and in neurodegeneration, with a focus on alzheimer's disease (ad), frontotemporal dementia (ftd), amyotrophic lateral sclerosis, progressive supranuclear palsy, parkinson's disease (pd), dementia with lewy bodies (dlb), multiple system atrophy, and huntington's disease. |
2021-07-28 |
2023-08-13 |
Not clear |
| Rita Guerreiro, Elizabeth Gibbons, Miguel Tábuas-Pereira, Celia Kun-Rodrigues, Gustavo C Santo, Jose Bra. Genetic architecture of common non-Alzheimer's disease dementias. Neurobiology of disease. vol 142. 2021-07-27. PMID:32439597. |
frontotemporal dementia (ftd), dementia with lewy bodies (dlb) and vascular dementia (vad) are the most common forms of dementia after alzheimer's disease (ad). |
2021-07-27 |
2023-08-13 |
Not clear |
| Insup Choi, Steven P Seegobin, Dongxiao Liang, Zhenyu Yu. Synucleinphagy: a microglial "community cleanup program" for neuroprotection. Autophagy. vol 16. issue 9. 2021-07-27. PMID:32453651. |
snca/α-synuclein is a major component in the lewy body (lb), a pathological hallmark of parkinson disease (pd) and dementia with lewy body (dlb), collectively known as synucleinopathies. |
2021-07-27 |
2023-08-13 |
mouse |
| Hannah Bender, Simone A Fietz, Franziska Richter, Milos Stanojlovi. Alpha-Synuclein Pathology Coincides With Increased Number of Early Stage Neural Progenitors in the Adult Hippocampus. Frontiers in cell and developmental biology. vol 9. 2021-07-27. PMID:34307368. |
alpha-synuclein pathology driven impairment in adult neurogenesis was proposed as a potential cause of, or at least contributor to, memory impairment observed in both patients and animal models of parkinson's disease (pd) and dementia with lewy bodies (dlb). |
2021-07-27 |
2023-08-13 |
mouse |
| Ángela Milán-Tomás, Marta Fernández-Matarrubia, María Cruz Rodríguez-Oro. Lewy Body Dementias: A Coin with Two Sides? Behavioral sciences (Basel, Switzerland). vol 11. issue 7. 2021-07-25. PMID:34206456. |
lewy body dementias (lbds) consist of dementia with lewy bodies (dlb) and parkinson's disease dementia (pdd), which are clinically similar syndromes that share neuropathological findings with widespread cortical lewy body deposition, often with a variable degree of concomitant alzheimer pathology. |
2021-07-25 |
2023-08-13 |
Not clear |