| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Frederick M Lang, Daniel Y Kwon, Dag Aarsland, Brad Boeve, Babak Tousi, Mark Harnett, Yi Mo, Marwan Noel Sabbag. An international, randomized, placebo-controlled, phase 2b clinical trial of intepirdine for dementia with Lewy bodies (HEADWAY-DLB). Alzheimer's & dementia (New York, N. Y.). vol 7. issue 1. 2021-07-01. PMID:34189249. |
a phase 2b clinical trial, headway-dlb, was performed to assess treatment with intepirdine, a serotonin receptor antagonist, in patients with dementia with lewy bodies (dlb). |
2021-07-01 |
2023-08-13 |
Not clear |
| Victor Calil, Felipe Kenji Sudo, Gustavo Santiago-Bravo, Marco Antonio Lima, Paulo Matto. Anosognosia in dementia with Lewy bodies: a systematic review. Arquivos de neuro-psiquiatria. vol 79. issue 4. 2021-06-29. PMID:34133514. |
although dementia with lewy bodies (dlb) is the second most common form of degenerative dementia, literature on anosognosia in this disease is scarce. |
2021-06-29 |
2023-08-13 |
Not clear |
| M Takahashi, T Uchihara, M Yoshida, K Wakabayashi, A Kakita, H Takahashi, S Toru, S Orim. Clinical and pathological features affecting cardiac sympathetic denervation in autopsy-confirmed dementia with Lewy bodies. European journal of neurology. vol 27. issue 7. 2021-06-25. PMID:32239599. |
the aim was to clarify the features affecting cardiac sympathetic denervation in autopsy-confirmed dementia with lewy bodies (dlb) patients. |
2021-06-25 |
2023-08-13 |
Not clear |
| Carla Abdelnour, Daniel Ferreira, Ketil Oppedal, Lena Cavallin, Olivier Bousiges, Lars Olof Wahlund, Jakub Hort, Zuzana Nedelska, Alessandro Padovani, Andrea Pilotto, Laura Bonanni, Milica G Kramberger, Mercè Boada, Eric Westman, Javier Pagonabarraga, Jaime Kulisevsky, Frédéric Blanc, Dag Aarslan. The combined effect of amyloid-β and tau biomarkers on brain atrophy in dementia with Lewy bodies. NeuroImage. Clinical. vol 27. 2021-06-25. PMID:32674011. |
alzheimer's disease (ad)-related pathology is frequently found in patients with dementia with lewy bodies (dlb). |
2021-06-25 |
2023-08-13 |
Not clear |
| E E Wolters, M van de Beek, R Ossenkoppele, S S V Golla, S C J Verfaillie, E M Coomans, T Timmers, D Visser, H Tuncel, F Barkhof, R Boellaard, A D Windhorst, W M van der Flier, Ph Scheltens, A W Lemstra, B N M van Bercke. Tau PET and relative cerebral blood flow in dementia with Lewy bodies: A PET study. NeuroImage. Clinical. vol 28. 2021-06-25. PMID:33395993. |
alpha-synuclein often co-occurs with alzheimer's disease (ad) pathology in dementia with lewy bodies (dlb). |
2021-06-25 |
2023-08-13 |
Not clear |
| Julia Schumacher, Alan J Thomas, Luis R Peraza, Michael Firbank, Ruth Cromarty, Calum A Hamilton, Paul C Donaghy, John T O'Brien, John-Paul Taylo. EEG alpha reactivity and cholinergic system integrity in Lewy body dementia and Alzheimer's disease. Alzheimer's research & therapy. vol 12. issue 1. 2021-06-24. PMID:32321573. |
lewy body dementia (lbd), which includes dementia with lewy bodies (dlb) and parkinson's disease dementia (pdd), is characterised by marked deficits within the cholinergic system which are more severe than in alzheimer's disease (ad) and are mainly caused by degeneration of the nucleus basalis of meynert (nbm) whose widespread cholinergic projections provide the main source of cortical cholinergic innervation. |
2021-06-24 |
2023-08-13 |
Not clear |
| Olivier Bousiges, Nathalie Philippi, Thomas Lavaux, Armand Perret-Liaudet, Ingolf Lachmann, Caroline Schaeffer-Agalède, Pierre Anthony, Anne Botzung, Lucie Rauch, Barbara Jung, Paulo Loureiro de Sousa, Catherine Demuynck, Catherine Martin-Hunyadi, Benjamin Cretin, Frédéric Blan. Differential diagnostic value of total alpha-synuclein assay in the cerebrospinal fluid between Alzheimer's disease and dementia with Lewy bodies from the prodromal stage. Alzheimer's research & therapy. vol 12. issue 1. 2021-06-24. PMID:32993772. |
several studies have investigated the value of alpha-synuclein assay in the cerebrospinal fluid (csf) of alzheimer's disease (ad) and dementia with lewy bodies (dlb) patients in the differential diagnosis of these two pathologies. |
2021-06-24 |
2023-08-13 |
Not clear |
| Jacqui T Nimmo, Ajay Verma, Jean-Cosme Dodart, Chang Yi Wang, Jimmy Savistchenko, Ronald Melki, Roxana O Carare, James A R Nicol. Novel antibodies detect additional α-synuclein pathology in synucleinopathies: potential development for immunotherapy. Alzheimer's research & therapy. vol 12. issue 1. 2021-06-24. PMID:33256825. |
alpha-synuclein (α-syn) aggregation is the primary characteristic of synucleinopathies including parkinson's disease (pd), dementia with lewy bodies (dlb) and multiple system atrophy (msa). |
2021-06-24 |
2023-08-13 |
human |
| A Surendranathan, J Kane, A Bentley, S Barker, R McNally, C Bamford, J-P Taylor, A Thomas, I McKeith, D Burn, J T O'Brie. Introduction of an assessment toolkit associated with increased rate of DLB diagnosis. Alzheimer's research & therapy. vol 13. issue 1. 2021-06-24. PMID:33608039. |
dementia with lewy bodies (dlb) and dementia in parkinson's disease (pdd) are recognised to be under-recognised in clinical practice in the uk, with only one third to a half of expected cases diagnosed. |
2021-06-24 |
2023-08-13 |
Not clear |
| M van de Beek, I van Steenoven, J J van der Zande, I Porcelijn, F Barkhof, C J Stam, P G H M Raijmakers, P Scheltens, C E Teunissen, W M van der Flier, A W Lemstr. Characterization of symptoms and determinants of disease burden in dementia with Lewy bodies: DEvELOP design and baseline results. Alzheimer's research & therapy. vol 13. issue 1. 2021-06-24. PMID:33637117. |
the dementia with lewy bodies project (develop) aims to phenotype patients with dementia with lewy bodies (dlb) and study the symptoms and biomarkers over time. |
2021-06-24 |
2023-08-13 |
Not clear |
| Robert Espinosa, Matthew Davis, Scott Johnson, Stephanie Cline, Daniel Weintrau. Direct Medical Costs of Dementia With Lewy Bodies by Disease Complexity. Journal of the American Medical Directors Association. vol 21. issue 11. 2021-06-23. PMID:32773201. |
there is currently no accurate profile of the economic burden of dementia with lewy bodies (dlb), particularly any examination of the direct medical costs of dlb by the number of affected clinical domains. |
2021-06-23 |
2023-08-13 |
Not clear |
| Niccolo Candelise, Matthias Schmitz, Katrin Thüne, Maria Cramm, Alberto Rabano, Saima Zafar, Erik Stoops, Hugo Vanderstichele, Anna Villar-Pique, Franc Llorens, Inga Zer. Effect of the micro-environment on α-synuclein conversion and implication in seeded conversion assays. Translational neurodegeneration. vol 9. 2021-06-22. PMID:31988747. |
intracellular inclusions of α-synuclein, referred to as lewy bodies (lbs), are pathological hallmarks of α-synucleinopathies, such as parkinson's disease (pd) or dementia with lewy bodies (dlb). |
2021-06-22 |
2023-08-13 |
Not clear |
| M van de Beek, R Babapour Mofrad, I van Steenoven, H Vanderstichele, P Scheltens, C E Teunissen, A W Lemstra, W M van der Flie. Sex-specific associations with cerebrospinal fluid biomarkers in dementia with Lewy bodies. Alzheimer's research & therapy. vol 12. issue 1. 2021-06-22. PMID:32303272. |
dementia with lewy bodies (dlb) is more prevalent in men than in women. |
2021-06-22 |
2023-08-13 |
Not clear |
| Kevin Kyle, Jeff M Bronstei. Treatment of psychosis in Parkinson's disease and dementia with Lewy Bodies: A review. Parkinsonism & related disorders. vol 75. 2021-06-22. PMID:32480308. |
there is a considerable overlap between parkinson's disease dementia (pdd) and dementia with lewy bodies (dlb). |
2021-06-22 |
2023-08-13 |
Not clear |
| Lucy Honeycutt, Jean-François Gagnon, Amélie Pelletier, Jessie De Roy, Jacques Y Montplaisir, Ronald B Postum. Pareidolias and cognition in isolated REM sleep behavior disorder. Parkinsonism & related disorders. vol 75. 2021-06-22. PMID:32492550. |
though visual illusions and hallucinations are common in dementia with lewy bodies (dlb) and parkinson's disease (pd), they are not typically observed clinically in prodromal stages, including isolated rem sleep behavior disorder (irbd). |
2021-06-22 |
2023-08-13 |
Not clear |
| Masayuki Miyamoto, Tomoyuki Miyamot. Relationship of substantia nigra hyperechogenicity to risk of Lewy body disease in idiopathic REM sleep behavior disorder patients: a longitudinal study. Sleep medicine. vol 68. 2021-06-21. PMID:32018190. |
we examined the relationship between baseline substantia nigra (sn) echogenicity on transcranial sonography (tcs) images and medium-to long-term developments of parkinson's disease (pd) and dementia with lewy bodies (dlb) in idiopathic rbd (irbd) patients. |
2021-06-21 |
2023-08-13 |
Not clear |
| Yuka Oishi, Toru Imamura, Tatsuo Shimomura, Kyoko Suzuk. Visual texture agnosia influences object identification in dementia with Lewy bodies and Alzheimer's disease. Cortex; a journal devoted to the study of the nervous system and behavior. vol 129. 2021-06-21. PMID:32422422. |
numerous studies have shown visuoperceptual/visuospatial deficits in dementia with lewy bodies (dlb) and alzheimer's disease (ad). |
2021-06-21 |
2023-08-13 |
Not clear |
| Susan M L Banks, Audrey T Medeiros, Molly McQuillan, David J Busch, Ana Sofia Ibarraran-Viniegra, Rui Sousa, Eileen M Lafer, Jennifer R Morga. Hsc70 Ameliorates the Vesicle Recycling Defects Caused by Excess α-Synuclein at Synapses. eNeuro. vol 7. issue 1. 2021-06-18. PMID:31941659. |
α-synuclein overexpression and aggregation are linked to parkinson's disease (pd), dementia with lewy bodies (dlb), and several other neurodegenerative disorders. |
2021-06-18 |
2023-08-13 |
human |
| Danielle Walu Kasongo, Gioacchino de Leo, Nunzio Vicario, Giampiero Leanza, Giuseppe Legnam. Chronic α-Synuclein Accumulation in Rat Hippocampus Induces Lewy Bodies Formation and Specific Cognitive Impairments. eNeuro. vol 7. issue 3. 2021-06-18. PMID:32393581. |
occurrence of lewy bodies (lbs)/lewy neurites (lns) containing misfolded fibrillar α-synuclein (α-syn) is one of the pathologic hallmarks of memory impairment-linked synucleinopathies, such as parkinson's disease (pd) and dementia with lbs (dlb). |
2021-06-18 |
2023-08-13 |
mouse |
| Jay Amin, Clive Holmes, Robert B Dorey, Emanuele Tommasino, Yuri R Casal, Daisy M Williams, Charles Dupuy, James A R Nicoll, Delphine Boch. Neuroinflammation in dementia with Lewy bodies: a human post-mortem study. Translational psychiatry. vol 10. issue 1. 2021-06-18. PMID:32747635. |
dementia with lewy bodies (dlb) is the second most common neurodegenerative cause of dementia, behind alzheimer's disease (ad). |
2021-06-18 |
2023-08-13 |
human |