Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
Julia Schumacher, Jeffrey L Gunter, Scott A Przybelski, David T Jones, Jonathan Graff-Radford, Rodolfo Savica, Christopher G Schwarz, Matthew L Senjem, Clifford R Jack, Val J Lowe, David S Knopman, Julie A Fields, Walter K Kremers, Ronald C Petersen, Neill R Graff-Radford, Tanis J Ferman, Bradley F Boeve, Alan J Thomas, John-Paul Taylor, Kejal Kantarc. Dementia with Lewy bodies: association of Alzheimer pathology with functional connectivity networks. Brain : a journal of neurology. vol 144. issue 10. 2021-12-09. PMID:34114602. |
dementia with lewy bodies (dlb) is neuropathologically defined by the presence of α-synuclein aggregates, but many dlb cases show concurrent alzheimer's disease pathology in the form of amyloid-β plaques and tau neurofibrillary tangles. |
2021-12-09 |
2023-08-13 |
human |
Daniel Alejandro Drubac. Twilight and Me: A Soliloquy. Continuum (Minneapolis, Minn.). vol 27. issue 6. 2021-12-09. PMID:34881738. |
dementia with lewy bodies (dlb) is the third most frequent type of dementia. |
2021-12-09 |
2023-08-13 |
Not clear |
Lisa Fellner, Elisa Gabassi, Johannes Haybaeck, Frank Edenhofe. Autophagy in α-Synucleinopathies-An Overstrained System. Cells. vol 10. issue 11. 2021-12-08. PMID:34831366. |
alpha-synucleinopathies comprise progressive neurodegenerative diseases, including parkinson's disease (pd), dementia with lewy bodies (dlb), and multiple system atrophy (msa). |
2021-12-08 |
2023-08-13 |
Not clear |
Arianna Manini, Letizia Straniero, Edoardo Monfrini, Marco Percetti, Maria Vizziello, Giulia Franco, Valeria Rimoldi, Anna Zecchinelli, Gianni Pezzoli, Stefania Corti, Giacomo Pietro Comi, Stefano Duga, Alessio Di Fonz. Screening of LRP10 mutations in Parkinson's disease patients from Italy. Parkinsonism & related disorders. vol 89. 2021-12-07. PMID:34216936. |
recently, lrp10 has been associated with pd, parkinson's disease dementia (pdd) and dementia with lewy bodies (dlb) by linkage analysis and positional cloning in an italian family with late-onset pd. |
2021-12-07 |
2023-08-13 |
Not clear |
Per Borghammer, Jacob Horsager, Katrine Andersen, Nathalie Van Den Berge, Anna Raunio, Shigeo Murayama, Laura Parkkinen, Liisa Myllykanga. Neuropathological evidence of body-first vs. brain-first Lewy body disease. Neurobiology of disease. vol 161. 2021-12-07. PMID:34763110. |
aggregation of alpha-synuclein into inclusion bodies, termed lewy pathology, is a defining feature of parkinson's disease (pd) and dementia with lewy bodies (dlb). |
2021-12-07 |
2023-08-13 |
Not clear |
Wen-Ying Ma, Min-Jie Tian, Qun Yao, Qian Li, Fan-Yu Tang, Chao-Yong Xiao, Jing-Ping Shi, Jiu Che. Neuroimaging alterations in dementia with Lewy bodies and neuroimaging differences between dementia with Lewy bodies and Alzheimer's disease: An activation likelihood estimation meta-analysis. CNS neuroscience & therapeutics. 2021-12-07. PMID:34873859. |
the aim of this study was to identify brain regions with local, structural, and functional abnormalities in dementia with lewy bodies (dlb) and uncover the differences between dlb and alzheimer's disease (ad). |
2021-12-07 |
2023-08-13 |
Not clear |
John A Duignan, Aoife Haughey, Justin A Kinsella, Ronan P Killee. Molecular and Anatomical Imaging of Dementia With Lewy Bodies and Frontotemporal Lobar Degeneration. Seminars in nuclear medicine. vol 51. issue 3. 2021-12-02. PMID:33402272. |
dementia with lewy bodies (dlb) and frontotemporal lobar degeneration (ftld) are common causes of dementia. |
2021-12-02 |
2023-08-13 |
Not clear |
John A Duignan, Aoife Haughey, Justin A Kinsella, Ronan P Killee. Molecular and Anatomical Imaging of Dementia With Lewy Bodies and Frontotemporal Lobar Degeneration. Seminars in nuclear medicine. vol 51. issue 3. 2021-12-02. PMID:33402272. |
structural and functional imaging combined can aid differential diagnosis and help to discriminate dlb or ftld from other forms of dementia. |
2021-12-02 |
2023-08-13 |
Not clear |
Satoshi Minoshima, Karina Mosci, Donna Cross, Tanyaluck Thientunyaki. Brain [F-18]FDG PET for Clinical Dementia Workup: Differential Diagnosis of Alzheimer's Disease and Other Types of Dementing Disorders. Seminars in nuclear medicine. vol 51. issue 3. 2021-12-02. PMID:33546814. |
pet images with [f-18]fdg demonstrate distinct patterns of decreased uptake for alzheimer's disease (ad), dementia with lewy bodies (dlb), and frontotemporal dementia (ftd) as well as its multiple subtypes such as behavioral variant ftd, primary progressive aphasia (ppa), progressive supranuclear palsy, and corticobasal degeneration to aid in the differential diagnoses. |
2021-12-02 |
2023-08-13 |
Not clear |
Daniel Ferreira, Zuzana Nedelska, Jonathan Graff-Radford, Scott A Przybelski, Timothy G Lesnick, Christopher G Schwarz, Hugo Botha, Matthew L Senjem, Julie A Fields, David S Knopman, Rodolfo Savica, Tanis J Ferman, Neill R Graff-Radford, Val J Lowe, Clifford R Jack, Ronald C Petersen, Afina W Lemstra, Marleen van de Beek, Frederik Barkhof, Frederic Blanc, Paulo Loureiro de Sousa, Nathalie Philippi, Benjamin Cretin, Catherine Demuynck, Jakub Hort, Ketil Oppedal, Bradley F Boeve, Dag Aarsland, Eric Westman, Kejal Kantarc. Cerebrovascular disease, neurodegeneration, and clinical phenotype in dementia with Lewy bodies. Neurobiology of aging. vol 105. 2021-12-01. PMID:34130107. |
we investigated whether cerebrovascular disease contributes to neurodegeneration and clinical phenotype in dementia with lewy bodies (dlb). |
2021-12-01 |
2023-08-13 |
Not clear |
Faheem Arshad, Feba Varghese, Avanthi Paplikar, Yashwanth Gangadhar, Subasree Ramakrishnan, Jaydip Ray Chaudhuri, Anita Mahadevan, Suvarna Allad. Role of Autoantibodies in Neurodegenerative Dementia: An Emerging Association. Dementia and geriatric cognitive disorders. vol 50. issue 2. 2021-12-01. PMID:34237731. |
the objective was to study the frequency and profile of disease-specific autoantibodies in alzheimer's dementia (ad), frontotemporal dementia (ftd), and dementia with lewy bodies (dlb). |
2021-12-01 |
2023-08-13 |
Not clear |
David S Goldstein, Risa Isonaka, Guillaume Lamotte, Horacio Kaufman. Different phenoconversion pathways in pure autonomic failure with versus without Lewy bodies. Clinical autonomic research : official journal of the Clinical Autonomic Research Society. vol 31. issue 6. 2021-12-01. PMID:34669076. |
longitudinal studies have reported that paf can phenoconvert to a central synucleinopathy with motor or cognitive involvement-i.e., to parkinson disease (pd), dementia with lewy bodies (dlb), or multiple system atrophy (msa). |
2021-12-01 |
2023-08-13 |
Not clear |
Elijah Mak, Nicolas Nicastro, Maura Malpetti, George Savulich, Ajenthan Surendranathan, Negin Holland, Luca Passamonti, P Simon Jones, Stephen F Carter, Li Su, Young T Hong, Tim D Fryer, Guy B Williams, Franklin Aigbirhio, James B Rowe, John T O'Brie. Imaging tau burden in dementia with Lewy bodies using [ Neurobiology of aging. vol 101. 2021-11-30. PMID:33631469. |
imaging tau burden in dementia with lewy bodies using [ alzheimer's disease (ad) pathology is frequently observed as a comorbidity in people with dementia with lewy bodies (dlb). |
2021-11-30 |
2023-08-13 |
Not clear |
Angus Lau, Iman Beheshti, Mandana Modirrousta, Tiffany A Kolesar, Andrew L Goertzen, Ji Hyun K. Alzheimer's Disease-Related Metabolic Pattern in Diverse Forms of Neurodegenerative Diseases. Diagnostics (Basel, Switzerland). vol 11. issue 11. 2021-11-30. PMID:34829370. |
dementia has many causes including alzheimer's disease (ad), dementia with lewy bodies (dlb), and frontotemporal lobar degeneration (ftld). |
2021-11-30 |
2023-08-13 |
human |
Melissa J Armstron. Advances in dementia with Lewy bodies. Therapeutic advances in neurological disorders. vol 14. 2021-11-30. PMID:34840608. |
dementia with lewy bodies (dlb) is a clinical diagnosis representing a specific presentation of a pathological α-synucleinopathy (lewy body disease). |
2021-11-30 |
2023-08-13 |
Not clear |
Melissa J Armstrong, Noheli Gamez, Slande Alliance, Tabassum Majid, Angela S Taylor, Andrea M Kurasz, Bhavana Patel, Glenn E Smit. Clinical Care and Unmet Needs of Individuals With Dementia With Lewy Bodies and Caregivers: An Interview Study. Alzheimer disease and associated disorders. vol 35. issue 4. 2021-11-29. PMID:34034295. |
patient-centered care requires understanding patient preferences and needs, but research on the clinical care preferences of individuals living with dementia and caregivers is sparse, particularly in dementia with lewy bodies (dlb). |
2021-11-29 |
2023-08-13 |
Not clear |
Sven J van der Lee, Inger van Steenoven, Marleen van de Beek, Niccolò Tesi, Iris E Jansen, Natasja M van Schoor, Marcel J T Reinders, Martijn Huisman, Philip Scheltens, Charlotte E Teunissen, Henne Holstege, Wiesje M van der Flier, Afina W Lemstr. Genetics Contributes to Concomitant Pathology and Clinical Presentation in Dementia with Lewy Bodies. Journal of Alzheimer's disease : JAD. vol 83. issue 1. 2021-11-26. PMID:34308904. |
dementia with lewy bodies (dlb) is a complex, progressive neurodegenerative disease with considerable phenotypic, pathological, and genetic heterogeneity. |
2021-11-26 |
2023-08-13 |
Not clear |
Kelly E Glajch, Tim E Moors, Yi Chen, Pascal A Bechade, Alice Y Nam, Molly M Rajsombath, Thomas D McCaffery, Ulf Dettmer, Andreas Weihofen, Warren D Hirst, Dennis J Selkoe, Silke Nube. Wild-type GBA1 increases the α-synuclein tetramer-monomer ratio, reduces lipid-rich aggregates, and attenuates motor and cognitive deficits in mice. Proceedings of the National Academy of Sciences of the United States of America. vol 118. issue 31. 2021-11-25. PMID:34326260. |
loss-of-function mutations in acid beta-glucosidase 1 (gba1) are among the strongest genetic risk factors for lewy body disorders such as parkinson's disease (pd) and lewy body dementia (dlb). |
2021-11-25 |
2023-08-13 |
mouse |
Antoine Brangier, Nathalie Jomard, Alice Duvivier, Claire Paquet, Frédéric Blan. [Assessment of the knowledge of Lewy body disease by health care professionnels compared to Alzheimer's disease: result of a descriptive analytical study]. Geriatrie et psychologie neuropsychiatrie du vieillissement. vol 19. issue 3. 2021-11-25. PMID:34405805. |
dementia with lewy body (dlb) is a common neurodegenerative disease that warrants specific care, which remains largely underdiagnosed. |
2021-11-25 |
2023-08-13 |
Not clear |
Matthieu Sacrez, Margot Lamothe, Lucie Rauch, Anne Botzung, Frédéric Blan. [Therapeutic trials in dementia with Lewy bodies: a systematic review of the literature]. Geriatrie et psychologie neuropsychiatrie du vieillissement. vol 19. issue 3. 2021-11-25. PMID:34609295. |
cognitive diseases with lewy bodies occur in two forms: dementia with lewy bodies (dlb) and parkinson's disease dementia (pdd), which follows the progression of parkinson's disease. |
2021-11-25 |
2023-08-13 |
Not clear |