| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Fabian Leys, Gregor K Wenning, Alessandra Fanciull. The role of cardiovascular autonomic failure in the differential diagnosis of α-synucleinopathies. Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology. 2021-11-24. PMID:34817726. |
the α-synucleinopathies comprise a group of adult-onset neurodegenerative disorders including parkinson's disease (pd), multiple system atrophy (msa), dementia with lewy bodies (dlb,) and - as a restricted non-motor form - pure autonomic failure (paf). |
2021-11-24 |
2023-08-13 |
Not clear |
| Chenjie Xia, Ronald B Postum. Diagnosing multiple system atrophy at the prodromal stage. Clinical autonomic research : official journal of the Clinical Autonomic Research Society. vol 30. issue 3. 2021-11-24. PMID:32232688. |
prodromal diagnostic criteria were recently developed for parkinson's disease (pd) and are forthcoming for dementia with lewy bodies (dlb). |
2021-11-24 |
2023-08-13 |
Not clear |
| Longfei Jia, Min Zhu, Jianwei Yang, Yana Pang, Qi Wang, Ying Li, Tingting Li, Fangyu Li, Qigeng Wang, Yan Li, Yiping We. Prediction of P-tau/Aβ42 in the cerebrospinal fluid with blood microRNAs in Alzheimer's disease. BMC medicine. vol 19. issue 1. 2021-11-23. PMID:34775974. |
here, we report a panel of micrornas (mirnas) in serum that can predict p-tau/aβ42 in csf and readily differentiate ad from other dementias, including vascular dementia (vad), parkinson disease dementia (pdd), behavioral variant frontotemporal dementia (bvftd), and dementia with lewy body (dlb). |
2021-11-23 |
2023-08-13 |
Not clear |
| Christopher Simon, Tomoko Soga, Hirotaka James Okano, Ishwar Parha. α-Synuclein-mediated neurodegeneration in Dementia with Lewy bodies: the pathobiology of a paradox. Cell & bioscience. vol 11. issue 1. 2021-11-23. PMID:34798911. |
dementia with lewy bodies (dlb) is epitomized by the pathognomonic manifestation of α-synuclein-laden lewy bodies within selectively vulnerable neurons in the brain. |
2021-11-23 |
2023-08-13 |
Not clear |
| Jun Yup Lee, Oana C Marian, Anthony S Do. Defective Lysosomal Lipid Catabolism as a Common Pathogenic Mechanism for Dementia. Neuromolecular medicine. vol 23. issue 1. 2021-11-22. PMID:33550528. |
the most common forms of dementia are alzheimer's disease (ad), vascular dementia, frontotemporal dementia (ftd), and lewy body dementia, which includes parkinson's disease (pd) dementia and dementia with lewy bodies (dlb). |
2021-11-22 |
2023-08-13 |
mouse |
| Marcella Reale, Claudia Carrarini, Mirella Russo, Fedele Dono, Laura Ferri, Martina Di Pietro, Erica Costantini, Annamaria Porreca, Marta Di Nicola, Marco Onofrj, Laura Bonann. Muscarinic Receptors Expression in the Peripheral Blood Cells Differentiate Dementia with Lewy Bodies from Alzheimer's Disease. Journal of Alzheimer's disease : JAD. 2021-11-22. PMID:34806612. |
central nervous system disruption of cholinergic (ach) signaling, which plays a major role in cognitive processes, is well documented in dementia with lewy bodies (dlb) and alzheimer's disease (ad). |
2021-11-22 |
2023-08-13 |
Not clear |
| Tae-Eun Kim, Andrew J Newman, Thibaut Imberdis, Lisa Brontesi, Arati Tripathi, Nagendran Ramalingam, Saranna Fanning, Dennis Selkoe, Ulf Dettme. Excess membrane binding of monomeric alpha-, beta- and gamma-synuclein is invariably associated with inclusion formation and toxicity. Human molecular genetics. vol 30. issue 23. 2021-11-20. PMID:34254125. |
α-synuclein (αs) has been well-documented to play a role in human synucleinopathies such as parkinson's disease (pd) and dementia with lewy bodies (dlb). |
2021-11-20 |
2023-08-13 |
human |
| Matteo Bauckneht, Andrea Chincarini, Matthias Brendel, Axel Rominger, Leonie Beyer, Rose Bruffaerts, Rik Vandenberghe, Milica G Kramberger, Maja Trost, Valentina Garibotto, Nicolas Nicastro, Giovanni B Frisoni, Afina W Lemstra, Bart N M van Berckel, Andrea Pilotto, Alessandro Padovani, Miguel A Ochoa-Figueroa, Anette Davidsson, Valle Camacho, Enrico Peira, Dario Arnaldi, Matteo Pardini, Maria Isabella Donegani, Stefano Raffa, Alberto Miceli, Gianmario Sambuceti, Dag Aarsland, Flavio Nobili, Silvia Morbell. Associations among education, age, and the dementia with Lewy bodies (DLB) metabolic pattern: A European-DLB consortium project. Alzheimer's & dementia : the journal of the Alzheimer's Association. vol 17. issue 8. 2021-11-19. PMID:33528089. |
associations among education, age, and the dementia with lewy bodies (dlb) metabolic pattern: a european-dlb consortium project. |
2021-11-19 |
2023-08-13 |
Not clear |
| Matteo Bauckneht, Andrea Chincarini, Matthias Brendel, Axel Rominger, Leonie Beyer, Rose Bruffaerts, Rik Vandenberghe, Milica G Kramberger, Maja Trost, Valentina Garibotto, Nicolas Nicastro, Giovanni B Frisoni, Afina W Lemstra, Bart N M van Berckel, Andrea Pilotto, Alessandro Padovani, Miguel A Ochoa-Figueroa, Anette Davidsson, Valle Camacho, Enrico Peira, Dario Arnaldi, Matteo Pardini, Maria Isabella Donegani, Stefano Raffa, Alberto Miceli, Gianmario Sambuceti, Dag Aarsland, Flavio Nobili, Silvia Morbell. Associations among education, age, and the dementia with Lewy bodies (DLB) metabolic pattern: A European-DLB consortium project. Alzheimer's & dementia : the journal of the Alzheimer's Association. vol 17. issue 8. 2021-11-19. PMID:33528089. |
we assessed the influence of education as a proxy of cognitive reserve and age on the dementia with lewy bodies (dlb) metabolic pattern. |
2021-11-19 |
2023-08-13 |
Not clear |
| Keita Sakurai, Daita Kaneda, Yuto Uchida, Shohei Inui, Masahiko Bundo, Akio Akagi, Takashi Nihashi, Yasuyuki Kimura, Takashi Kato, Kengo Ito, Wataru Ohashi, Yoshio Hashizum. Can Medial Temporal Impairment Be an Imaging Red Flag for Neurodegeneration in Disproportionately Enlarged Subarachnoid Space Hydrocephalus? Journal of Alzheimer's disease : JAD. vol 83. issue 3. 2021-11-19. PMID:34420966. |
the differentiation of idiopathic normal pressure hydrocephalus (inph) from neurodegenerative diseases such as alzheimer's disease (ad) and dementia with lewy bodies (dlb) is often challenging because of their non-specific symptoms. |
2021-11-19 |
2023-08-13 |
Not clear |
| Clare Tweedy, Nathan Kindred, Joshua Curry, Christopher Williams, John-Paul Taylor, Peter Atkinson, Fiona Randall, Daniel Erskine, Christopheer M Morris, Amy K Reeve, Gavin J Clowry, Fiona E N LeBea. Hippocampal network hyperexcitability in young transgenic mice expressing human mutant alpha-synuclein. Neurobiology of disease. vol 149. 2021-11-18. PMID:33347975. |
whether hyperexcitability is a core feature of alpha(α)-synucleinopathies, including dementia with lewy bodies (dlb) is unclear. |
2021-11-18 |
2023-08-13 |
mouse |
| Stefanie Smolders, Stéphanie Philtjens, David Crosiers, Anne Sieben, Elisabeth Hens, Bavo Heeman, Sara Van Mossevelde, Philippe Pals, Bob Asselbergh, Roberto Dos Santos Dias, Yannick Vermeiren, Rik Vandenberghe, Sebastiaan Engelborghs, Peter Paul De Deyn, Jean-Jacques Martin, Patrick Cras, Wim Annaert, Christine Van Broeckhove. Contribution of rare homozygous and compound heterozygous VPS13C missense mutations to dementia with Lewy bodies and Parkinson's disease. Acta neuropathologica communications. vol 9. issue 1. 2021-11-18. PMID:33579389. |
dementia with lewy bodies (dlb) and parkinson's disease (pd) are clinically, pathologically and etiologically disorders embedded in the lewy body disease (lbd) continuum, characterized by neuronal α-synuclein pathology. |
2021-11-18 |
2023-08-13 |
Not clear |
| Wojciech Kozubski, Kevin Ong, Wioletta Waleszczyk, Matthew Zabel, Jolanta Dorszewsk. Molecular Factors Mediating Neural Cell Plasticity Changes in Dementia Brain Diseases. Neural plasticity. vol 2021. 2021-11-18. PMID:33854544. |
vascular dementia (vad), parkinson's disease dementia (pdd), dementia with lewy bodies (dlb), and frontotemporal dementia (ftd) constitute much of the remaining cases. |
2021-11-18 |
2023-08-13 |
Not clear |
| Parichita Choudhury, Jonathan Graff-Radford, Jeremiah A Aakre, Lincoln Wurtz, David S Knopman, Neill R Graff-Radford, Kejal Kantarci, Leah K Forsberg, Julie A Fields, Otto Pedraza, Qin Chen, Toji Miyagawa, Gregory S Day, Philip Tipton, Rodolfo Savica, Hugo Botha, Christian Lachner, Brynn Dredla, R Ross Reichard, Ronald C Petersen, Dennis W Dickson, Bradley F Boeve, Tanis J Ferma. The temporal onset of the core features in dementia with Lewy bodies. Alzheimer's & dementia : the journal of the Alzheimer's Association. 2021-11-18. PMID:34761850. |
we examined the temporal sequence of the core features in probable dementia with lewy bodies (dlb). |
2021-11-18 |
2023-08-13 |
Not clear |
| Paz Cartas-Cejudo, Mercedes Lachén-Montes, Joaquín Fernández-Irigoyen, Enrique Santamarí. Tackling the Biological Meaning of the Human Olfactory Bulb Dyshomeostatic Proteome across Neurological Disorders: An Integrative Bioinformatic Approach. International journal of molecular sciences. vol 22. issue 21. 2021-11-18. PMID:34768771. |
for that, an integrative analysis was performed using ob proteomics datasets derived from subjects with alzheimer's disease (ad), parkinson's disease (pd), mixed dementia (mixd), dementia with lewy bodies (dlb), frontotemporal lobar degeneration (ftld-tdp43), progressive supranuclear palsy (psp) and amyotrophic lateral sclerosis (als) with respect to ob proteome data from neurologically intact controls. |
2021-11-18 |
2023-08-13 |
human |
| Masatoshi Inden, Ayaka Takagi, Hazuki Kitai, Taisei Ito, Hisaka Kurita, Ryo Honda, Yuji O Kamatari, Sora Nozaki, Xiaopeng Wen, Masanori Hijioka, Yoshihisa Kitamura, Isao Hozum. Kaempferol Has Potent Protective and Antifibrillogenic Effects for α-Synuclein Neurotoxicity In Vitro. International journal of molecular sciences. vol 22. issue 21. 2021-11-18. PMID:34768913. |
aggregation of α-synuclein (α-syn) is implicated in the pathogenesis of parkinson's disease (pd), dementia with lewy bodies (dlb), and multiple system atrophy (msa). |
2021-11-18 |
2023-08-13 |
Not clear |
| Sumita Raha, Debashis Dutta, Avik Roy, Kalipada Paha. Reduction of Lewy Body Pathology by Oral Cinnamon. Journal of neuroimmune pharmacology : the official journal of the Society on NeuroImmune Pharmacology. vol 16. issue 3. 2021-11-17. PMID:32889602. |
α-synucleinopathies in a broader sense comprise of several neurodegenerative disorders that primarily include parkinson's disease (pd), dementia with lewy bodies (dlb) and multiple system atrophy (msa). |
2021-11-17 |
2023-08-13 |
mouse |
| Nicolas Nicastro, Giedre Stripeikyte, Frédéric Assal, Valentina Garibotto, Olaf Blank. Premotor and fronto-striatal mechanisms associated with presence hallucinations in dementia with Lewy bodies. NeuroImage. Clinical. vol 32. 2021-11-17. PMID:34461436. |
presence hallucinations (ph) are frequent in dementia with lewy bodies (dlb), but their cortico-subcortical origin is unknown. |
2021-11-17 |
2023-08-13 |
human |
| Claudia Carrarini, Mirella Russo, Giada Pagliaccio, Fedele Dono, Raffaella Franciotti, Giulia Deluca, Stefania Nanni, Antonio Saracino, Marco Onofrj, Laura Bonann. Visual evoked potential abnormalities in dementia with Lewy bodies. Neurophysiologie clinique = Clinical neurophysiology. vol 51. issue 5. 2021-11-16. PMID:33653623. |
visuo-perceptual deficits and visual hallucinations (vhs) are common disturbances in patients with dementia with lewy bodies (dlb) and those with parkinson's disease (pd). |
2021-11-16 |
2023-08-13 |
Not clear |
| Izabela Winkel, Natalia Ermann, Agnieszka Żelwetro, Bożydar Sambor, Barbara Mroczko, Johannes Kornhuber, Bogusław Paradowski, Piotr Lewczu. Cerebrospinal fluid α synuclein concentrations in patients with positive AD biomarkers and extrapyramidal symptoms. Journal of neural transmission (Vienna, Austria : 1996). vol 128. issue 6. 2021-11-16. PMID:34036433. |
total α synuclein (αsyn) concentrations are frequently increased in the cerebrospinal fluid (csf) of ad patients, but are decreased in parkinson's disease (pd) and dementia with lewy bodies (dlb). |
2021-11-16 |
2023-08-13 |
human |