| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Jennifer L Imm, Joshua Harvey, Ehsan Pishva, Byron Creese, Leonidas Chouliaras, Emma Dempster, Clive Ballard, John T O'Brien, Dag Aarsland, Jonathan Mill, Katie Lunno. A role for epigenetic mechanisms in Lewy body dementias. Alzheimer's & dementia : the journal of the Alzheimer's Association. vol 17 Suppl 3. 2022-02-03. PMID:35108855. |
the lewy body diseases, dementia with lewy bodies (dlb), parkinson's disease (pd) and parkinson's disease dementia (pdd) are all neurodegenerative diseases classified by the accumulation of alpha-synuclein in neurons, forming lewy bodies (lb). |
2022-02-03 |
2023-08-13 |
Not clear |
| Konstantin Senkevich, Daria Nikanorova, Ludmila Protsenko, Eric Yu, Lynne Krohn, Kheireddin Mufti, Mehrdad A Estiar, Ziv Gan-O. Transcriptome analysis highlights common pathways between Alzheimer's disease, dementia with Lewy bodies and Parkinson's disease. Alzheimer's & dementia : the journal of the Alzheimer's Association. vol 17 Suppl 3. 2022-02-03. PMID:35108973. |
dementia with lewy bodies (dlb) has common clinical and pathological features with both ad and pd. |
2022-02-03 |
2023-08-13 |
Not clear |
| Usman Saeed, M Amin Banihashemi, Sandra E Black, Mario Maselli. The association of APOE-ε4 with clinicopathological, cognitive, neuropsychiatric, and neuroimaging features in α-synucleinopathies. Alzheimer's & dementia : the journal of the Alzheimer's Association. vol 17 Suppl 3. 2022-02-03. PMID:35109377. |
the ε4-allele of apolipoprotein e (apoe-ε4) presents an elevated risk not only for alzheimer's disease (ad), but also for parkinson's disease dementia (pdd) and dementia with lewy bodies (dlb). |
2022-02-03 |
2023-08-13 |
Not clear |
| Alberto Benussi, Andrea Pilotto, Valentina Cantoni, Elisabetta Ferrari, Barbara Borroni, Alessandro Padovan. Neurophysiological Correlates of Motor and Cognitive Dysfunction in Prodromal and Overt Dementia with Lewy Bodies. Journal of Alzheimer's disease : JAD. 2022-01-31. PMID:35094996. |
the neurophysiological correlates of cognitive and motor symptoms in prodromal and overt dementia with lewy bodies (dlb) are still to be elucidated. |
2022-01-31 |
2023-08-13 |
Not clear |
| Kyoko Numahata, Tomoyuki Miyamoto, Yasuhisa Akaiwa, Masayuki Miyamot. Brain Perfusion Single-Photon Emission Computed Tomography Using an Easy Z-Score Imaging System Predicts Progression to Neurodegenerative Dementia in Rapid Eye Movement Sleep Behavior Disorder. Dementia and geriatric cognitive disorders. 2022-01-31. PMID:35100582. |
longitudinal studies have reported that patients with idiopathic rapid eye movement sleep behavior disorder (irbd) have an increased risk of developing synucleinopathies, such as parkinson's disease and dementia with lewy bodies (dlb). |
2022-01-31 |
2023-08-13 |
Not clear |
| L J Li, J Yang, Y P Yuan, Y Y Wang, X J Liu, C Y Jiang, Y M X. [Application of skin phosphorylated synuclein in the diagnosis of dementia with Lewy body]. Zhonghua yi xue za zhi. vol 102. issue 5. 2022-01-30. PMID:35092980. |
patients with dementia with lewy body(dlb), alzheimer disease (ad), frontotemporal dementia (ftp), progressive supranuclear palsy (psp) and healthy controls in the department of neurology, the first affiliated hospital of zhengzhou university from august 2019 to march 2021 were recruited, with 3 in each group. |
2022-01-30 |
2023-08-13 |
Not clear |
| Daniela Gerovska, Marcos J Araúzo-Brav. The common incidence-age multistep model of neurodegenerative diseases revisited: wider general age range of incidence corresponds to fewer disease steps. Cell & bioscience. vol 12. issue 1. 2022-01-30. PMID:35093175. |
previously, we collected age-stratified incidence data of 404 epidemiological datasets of 10 neurodegenerative diseases (nds), namely amyotrophic lateral sclerosis (als), alzheimer's disease (ad), parkinson's disease (pd), huntington's disease (hd), fronto temporal dementia (ftd), dementia with lewy bodies (dlb), parkinsonism (pdm), parkinson's disease with dementia (pdd), creutzfeldt-jakob disease (cjd), and multiple sclerosis (ms). |
2022-01-30 |
2023-08-13 |
Not clear |
| Takashi Nakata, Kenichi Shimada, Akiko Iba, Haruhiko Oda, Akira Terashima, Yutaka Koide, Ryota Kawasaki, Takahiro Yamada, Kazunari Ishi. Correlation between noise pareidolia test scores for visual hallucinations and regional cerebral blood flow in dementia with Lewy bodies. Annals of nuclear medicine. 2022-01-29. PMID:35092551. |
this study aimed at investigating the correlation between recurrent visual hallucinations (vhs) and regional cerebral blood flow (rcbf) in patients with dementia with lewy bodies (dlb). |
2022-01-29 |
2023-08-13 |
Not clear |
| Bryan A Killinger, Lee L Marshall, Diptaman Chatterjee, Yaping Chu, Jose Bras, Rita Guerreiro, Jeffrey H Kordowe. In situ proximity labeling identifies Lewy pathology molecular interactions in the human brain. Proceedings of the National Academy of Sciences of the United States of America. vol 119. issue 5. 2022-01-27. PMID:35082147. |
the intracellular misfolding and accumulation of alpha-synuclein into structures collectively called lewy pathology (lp) is a central phenomenon for the pathogenesis of synucleinopathies, including parkinson's disease (pd) and dementia with lewy bodies (dlb). |
2022-01-27 |
2023-08-13 |
human |
| Marleen van de Beek, Floor A H Ooms, Jarith L Ebenau, Frederik Barkhof, Philip Scheltens, Charlotte E Teunissen, Argonde C van Harten, Wiesje M van der Flier, Afina W Lemstr. Association of the ATN Research Framework With Clinical Profile, Ccognitive Decline, and Mortality in Patients With Dementia With Lewy Bodies. Neurology. 2022-01-25. PMID:35074893. |
since ad pathology often coincides with dementia with lewy bodies (dlb), we aimed to investigate the distribution of atn profiles in dlb and associate atn-profiles in dlb to prognosis. |
2022-01-25 |
2023-08-13 |
Not clear |
| T S Usenko, K A Senkevich, A I Bezrukova, G V Baydakova, K S Basharova, A S Zhuravlev, E V Gracheva, A V Kudrevatykh, I V Miliukhina, I V Krasakov, L A Khublarova, I V Fursova, D V Zakharov, A A Timofeeva, Y A Irishina, E I Palchikova, N M Zalutskaya, A K Emelyanov, E Y Zakharova, S N Pchelin. Impaired Sphingolipid Hydrolase Activities in Dementia with Lewy Bodies and Multiple System Atrophy. Molecular neurobiology. 2022-01-23. PMID:35066761. |
the aim of the current study was to assess changes in activities of enzymes involved in ceramide metabolism in patients with different synucleinopathies (parkinson's disease (pd), dementia with lewy bodies (dlb), and multiple system atrophy (msa)). |
2022-01-23 |
2023-08-13 |
Not clear |
| Carla Abdelnour, Daniel Ferreira, Marleen van de Beek, Nira Cedres, Ketil Oppedal, Lena Cavallin, Frédéric Blanc, Olivier Bousiges, Lars-Olof Wahlund, Andrea Pilotto, Alessandro Padovani, Mercè Boada, Javier Pagonabarraga, Jaime Kulisevsky, Dag Aarsland, Afina W Lemstra, Eric Westma. Parsing heterogeneity within dementia with Lewy bodies using clustering of biological, clinical, and demographic data. Alzheimer's research & therapy. vol 14. issue 1. 2022-01-22. PMID:35063023. |
dementia with lewy bodies (dlb) includes various core clinical features that result in different phenotypes. |
2022-01-22 |
2023-08-13 |
Not clear |
| Shiori Awa, Genjiro Suzuki, Masami Masuda-Suzukake, Takashi Nonaka, Minoru Saito, Masato Hasegaw. Phosphorylation of endogenous α-synuclein induced by extracellular seeds initiates at the pre-synaptic region and spreads to the cell body. Scientific reports. vol 12. issue 1. 2022-01-22. PMID:35064139. |
accumulation of phosphorylated α-synuclein aggregates has been implicated in several diseases, such as parkinson's disease (pd) and dementia with lewy bodies (dlb), and is thought to spread in a prion-like manner. |
2022-01-22 |
2023-08-13 |
mouse |
| Yevgenia Rosenblum, Tamara Shiner, Noa Bregman, Firas Fahoum, Nir Giladi, Inbal Maidan, Anat Mirelma. Event-related oscillations differentiate between cognitive, motor and visual impairments. Journal of neurology. 2022-01-19. PMID:35043223. |
parkinson's disease (pd) and dementia with lewy bodies (dlb) share pathological and clinical similarities while differing in the timing and severity of motor cognitive and visual impairment. |
2022-01-19 |
2023-08-13 |
Not clear |
| Changyoun Kim, Armine Hovakimyan, Karen Zagorski, Tatevik Antonyan, Irina Petrushina, Hayk Davtyan, Gor Chailyan, Jonathan Hasselmann, Michiyo Iba, Anthony Adame, Edward Rockenstein, Marcell Szabo, Mathew Blurton-Jones, David H Cribbs, Anahit Ghochikyan, Eliezer Masliah, Michael G Agadjanya. Efficacy and immunogenicity of MultiTEP-based DNA vaccines targeting human α-synuclein: prelude for IND enabling studies. NPJ vaccines. vol 7. issue 1. 2022-01-11. PMID:35013319. |
dementia with lewy bodies (dlb) and parkinson's disease (pd) are characterized by the aberrant accumulation of α-syn intracytoplasmic lewy body inclusions and dystrophic lewy neurites resulting in neurodegeneration associated with inflammation. |
2022-01-11 |
2023-08-13 |
mouse |
| b' Kate\\xc5\\x99ina Men\\xc5\\xa1\\xc3\\xadkov\\xc3\\xa1, Radoslav Mat\\xc4\\x9bj, Carlo Colosimo, Raymond Rosales, Lucie Tu\\xc4\\x8dkov\\xc3\\xa1, Ji\\xc5\\x99\\xc3\\xad Ehrmann, Dominik Hrabo\\xc5\\xa1, Krist\\xc3\\xbdna Kola\\xc5\\x99\\xc3\\xadkov\\xc3\\xa1, Radek Vodi\\xc4\\x8dka, Radek Vrt\\xc4\\x9bl, Martin Proch\\xc3\\xa1zka, Martin Nevrl\\xc3\\xbd, Michaela Kaiserov\\xc3\\xa1, Sandra Kur\\xc4\\x8dov\\xc3\\xa1, Pavel Otruba, Petr Ka\\xc5\\x88ovsk\\xc3\\xb. Lewy body disease or diseases with Lewy bodies? NPJ Parkinson\'s disease. vol 8. issue 1. 2022-01-11. PMID:35013341.' |
the current nosological concept of α-synucleinopathies characterized by the presence of lewy bodies (lbs) includes parkinson's disease (pd), parkinson's disease dementia (pdd), and dementia with lewy bodies (dlb), for which the term "lewy body disease" (lbd) has recently been proposed due to their considerable clinical and pathological overlap. |
2022-01-11 |
2023-08-13 |
Not clear |
| Amina Nasri, Ikram Sghaier, Alya Gharbi, Saloua Mrabet, Mouna Ben Djebara, Amina Gargouri, Imen Kacem, Riadh Gouide. Role of Apolipoprotein E in the Clinical Profile of Atypical Parkinsonian Syndromes. Alzheimer disease and associated disorders. 2022-01-10. PMID:35001031. |
atypical parkinsonian syndromes (aps) encompass a spectrum of neurodegenerative diseases including dementia with lewy bodies (dlb), progressive supranuclear palsy (psp), multiple system atrophy (msa), and corticobasal syndrome (cbs). |
2022-01-10 |
2023-08-13 |
Not clear |
| Laiba Azhar, Raphael W Kusumo, Giovanni Marotta, Krista L Lanctôt, Nathan Herrman. Pharmacological Management of Apathy in Dementia. CNS drugs. 2022-01-10. PMID:35006557. |
the objective of this review was to summarize the drugs that have been studied for apathy treatment in patients with dementia (specifically alzheimer's disease [ad], huntington's disease [hd] and parkinson's disease [pd] dementia; dementia with lewy bodies [dlb]; vascular dementia [vad]; and frontotemporal dementia [ftd]) based on their putative mechanisms of action. |
2022-01-10 |
2023-08-13 |
Not clear |
| Laiba Azhar, Raphael W Kusumo, Giovanni Marotta, Krista L Lanctôt, Nathan Herrman. Pharmacological Management of Apathy in Dementia. CNS drugs. 2022-01-10. PMID:35006557. |
a total of 52 studies that included patients with ad (n = 33 studies), pd (n = 5), hd (n = 1), dlb (n = 1), ftd (n = 3), vad (n = 1), vad and ad (n = 4), vad and mixed dementia (n = 1), and ad, vad and mixed dementia (n = 3) were eligible for inclusion. |
2022-01-10 |
2023-08-13 |
Not clear |
| Yoshio Tsuboi, Kenji Kochi, Hidenori Maruyama, Yuji Matsumot. Zonisamide improves axial symptoms in dementia with Lewy bodies with parkinsonism: Post hoc analysis of clinical trials. eNeurologicalSci. vol 26. 2022-01-06. PMID:34988303. |
patients with dementia with lewy bodies (dlb) experience worsening axial symptoms with disease progression, which can negatively affect quality of life. |
2022-01-06 |
2023-08-13 |
Not clear |