| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Juan Idiaquez, Gustavo C Roma. Autonomic dysfunction in neurodegenerative dementias. Journal of the neurological sciences. vol 305. issue 1-2. 2012-04-03. PMID:21440258. |
syncope associated to orthostatic hypotension (oh), urinary incontinence and constipation is common symptoms in demented patients, mainly in dementia with lewy bodies (dlb) and in parkinson's disease dementia (pdd). |
2012-04-03 |
2023-08-12 |
Not clear |
| Mary Johnson, Antigoni Ekonomou, Carl Hobbs, Clive G Ballard, Robert H Perry, Elaine K Perr. Neurogenic marker abnormalities in the hippocampus in dementia with Lewy bodies. Hippocampus. vol 21. issue 10. 2012-04-02. PMID:20665591. |
dementia with lewy bodies (dlb) is associated with alpha synuclein pathology and slowly progressive dementia. |
2012-04-02 |
2023-08-12 |
Not clear |
| Yasuo Miki, Fumiaki Mori, Kunikazu Tanji, Akiyoshi Kakita, Hitoshi Takahashi, Koichi Wakabayash. Accumulation of histone deacetylase 6, an aggresome-related protein, is specific to Lewy bodies and glial cytoplasmic inclusions. Neuropathology : official journal of the Japanese Society of Neuropathology. vol 31. issue 6. 2012-03-16. PMID:21284752. |
previous studies have shown that hdac6 is concentrated in lewy bodies (lbs) in parkinson's disease (pd) and dementia with lbs (dlb) (cell 115: 727-738, 2003). |
2012-03-16 |
2023-08-12 |
human |
| Yumiko Yamane, Kazuo Sakai, Kiyoshi Maed. Dementia with Lewy bodies is associated with higher scores on the Geriatric Depression Scale than is Alzheimer's disease. Psychogeriatrics : the official journal of the Japanese Psychogeriatric Society. vol 11. issue 3. 2012-03-06. PMID:21951956. |
several reports suggest a higher morbidity of depression in patients with dementia with lewy bodies (dlb) than in patients with alzheimer's disease (ad). |
2012-03-06 |
2023-08-12 |
Not clear |
| Walter Maetzler, Anne Kathrin Stapf, Claudia Schulte, Ann-Kathrin Hauser, Stefanie Lerche, Isabel Wurster, Erwin Schleicher, Arthur Melms, Daniela Ber. Serum and cerebrospinal fluid uric acid levels in lewy body disorders: associations with disease occurrence and amyloid-β pathway. Journal of Alzheimer's disease : JAD. vol 27. issue 1. 2012-02-27. PMID:21765209. |
in this clinical study we were therefore interested in the role of ua in lewy body disorders (lbd), which includes parkinson's disease (pd) and a common form of neurodegenerative dementias, dementia with lewy bodies (dlb). |
2012-02-27 |
2023-08-12 |
Not clear |
| Flavio Nobili, Silvia Morbelli, Dario Arnaldi, Michela Ferrara, Claudio Campus, Andrea Brugnolo, Debora Mazzei, Naseri Mehrdad, Gianmario Sambuceti, Guido Rodrigue. Radionuclide brain imaging correlates of cognitive impairment in Parkinson's disease (PD). Journal of the neurological sciences. vol 310. issue 1-2. 2012-02-16. PMID:21762928. |
furthermore, deficit of acetylcholinesterase (ache) can be found by means of [11c]mp4a-pet already in early stage of pd, especially in posterior regions, then becoming more severe in pdd and in dementia with lewy bodies (dlb). |
2012-02-16 |
2023-08-12 |
Not clear |
| Marco Onofrj, Astrid Thomas, Pietro Tiraboschi, Gregor Wenning, Francesco Gambi, Gianna Sepede, Massimo Di Giannantonio, Caterina Di Carmine, Daniela Monaco, Valerio Maruotti, Fausta Ciccocioppo, Maria Chiara D'Amico, Laura Bonann. Updates on Somatoform Disorders (SFMD) in Parkinson's Disease and Dementia with Lewy Bodies and discussion of phenomenology. Journal of the neurological sciences. vol 310. issue 1-2. 2012-02-16. PMID:21813140. |
somatoform disorders (sfmd) were recently described in parkinson disease (pd) and dementia with lewy bodies (dlb). |
2012-02-16 |
2023-08-12 |
human |
| Marco Onofrj, Astrid Thomas, Pietro Tiraboschi, Gregor Wenning, Francesco Gambi, Gianna Sepede, Massimo Di Giannantonio, Caterina Di Carmine, Daniela Monaco, Valerio Maruotti, Fausta Ciccocioppo, Maria Chiara D'Amico, Laura Bonann. Updates on Somatoform Disorders (SFMD) in Parkinson's Disease and Dementia with Lewy Bodies and discussion of phenomenology. Journal of the neurological sciences. vol 310. issue 1-2. 2012-02-16. PMID:21813140. |
after 2-9 years of follow up, 488 patients were labelled as pd, 415 as alzheimer disease, 162 as dlb, 48 as progressive supranuclear palsy, 48 as multiple system atrophy and 49 as fronto-temporal dementia. |
2012-02-16 |
2023-08-12 |
human |
| Markus Weih, Umüt Degirmenci, Sebastian Kreil, Gerald Suttner, Daniela Schmidt, Johannes Kornhuber, Piotr Lewczuk, Torsten Kuwer. Nuclear medicine diagnostic techniques in the era of pathophysiology-based CSF biomarkers for Alzheimer's disease. Journal of Alzheimer's disease : JAD. vol 26 Suppl 3. 2012-02-09. PMID:21971454. |
numerous studies have shown the diagnostic value of reduced cbf and metabolic changes using perfusion-spect and fdg-pet in ad diagnosis as well as in differential diagnosis against frontotemporal dementia (ftd), dementia with lewy-bodies (dlb), and vascular cognitive disorders. |
2012-02-09 |
2023-08-12 |
Not clear |
| Zuzana Walker, Joanne Rodd. Dopaminergic imaging: clinical utility now and in the future. International psychogeriatrics. vol 23 Suppl 2. 2012-02-02. PMID:21843378. |
abnormalities in dopaminergic imaging measures are consistent features of dementia with lewy bodies (dlb) and other parkinsonian syndromes, and can be used to facilitate diagnosis, particularly in distinguishing between dlb and alzheimer's disease. |
2012-02-02 |
2023-08-12 |
Not clear |
| Michael J Firbank, Andrew M Blamire, Andrew Teodorczuk, Emma Teper, Emma J Burton, Dipayan Mitra, John T O'Brie. High resolution imaging of the medial temporal lobe in Alzheimer's disease and dementia with Lewy bodies. Journal of Alzheimer's disease : JAD. vol 21. issue 4. 2012-01-31. PMID:21504120. |
we used high resolution (0.3 mm in-plane) coronal 3t magnetic resonance (mr) imaging of the medial temporal lobe in 16 subjects with alzheimer's disease (ad), 16 with dementia with lewy bodies (dlb), and 16 similarly aged healthy subjects. |
2012-01-31 |
2023-08-12 |
human |
| Annika Ohrfelt, Henrik Zetterberg, Kerstin Andersson, Rita Persson, Dzemila Secic, Gunnar Brinkmalm, Anders Wallin, Ezra Mulugeta, Paul T Francis, Eugeen Vanmechelen, Dag Aarsland, Clive Ballard, Kaj Blennow, Ann Westman-Brinkmal. Identification of novel α-synuclein isoforms in human brain tissue by using an online nanoLC-ESI-FTICR-MS method. Neurochemical research. vol 36. issue 11. 2012-01-27. PMID:21674238. |
parkinson's disease (pd) and dementia with lewy bodies (dlb) are neurodegenerative diseases that are characterized by intra-neuronal inclusions of lewy bodies in distinct brain regions. |
2012-01-27 |
2023-08-12 |
human |
| Annika Ohrfelt, Henrik Zetterberg, Kerstin Andersson, Rita Persson, Dzemila Secic, Gunnar Brinkmalm, Anders Wallin, Ezra Mulugeta, Paul T Francis, Eugeen Vanmechelen, Dag Aarsland, Clive Ballard, Kaj Blennow, Ann Westman-Brinkmal. Identification of novel α-synuclein isoforms in human brain tissue by using an online nanoLC-ESI-FTICR-MS method. Neurochemical research. vol 36. issue 11. 2012-01-27. PMID:21674238. |
the different forms of α-syn were further studied by western blotting in brain tissue homogenates from the temporal cortex brodmann area 36 (ba36) and the dorsolateral prefrontal cortex ba9 derived from controls, patients with dlb and pd with dementia (pdd). |
2012-01-27 |
2023-08-12 |
human |
| R E J Musgrove, A E King, T C Dickso. Neuroprotective upregulation of endogenous α-synuclein precedes ubiquitination in cultured dopaminergic neurons. Neurotoxicity research. vol 19. issue 4. 2012-01-20. PMID:20617407. |
α-synuclein is the major protein component of lewy bodies--the pathological hallmark of parkinson's disease (pd) and dementia with lewy bodies (dlb). |
2012-01-20 |
2023-08-12 |
Not clear |
| Walter Maetzler, Daniela Berg, Matthis Synofzik, Kathrin Brockmann, Jana Godau, Arthur Melms, Thomas Gasser, Stephanie Hörnig, Markus Langkam. Autoantibodies against amyloid and glial-derived antigens are increased in serum and cerebrospinal fluid of Lewy body-associated dementias. Journal of Alzheimer's disease : JAD. vol 26. issue 1. 2012-01-10. PMID:21593566. |
there is increasing evidence that in lewy body-associated dementias (encompassing parkinson's disease with dementia (pdd) and dementia with lewy bodies (dlb)), the adaptive immune system is altered and the degenerative process includes glial cells in addition to neuronal structures. |
2012-01-10 |
2023-08-12 |
human |
| Walter Maetzler, Daniela Berg, Matthis Synofzik, Kathrin Brockmann, Jana Godau, Arthur Melms, Thomas Gasser, Stephanie Hörnig, Markus Langkam. Autoantibodies against amyloid and glial-derived antigens are increased in serum and cerebrospinal fluid of Lewy body-associated dementias. Journal of Alzheimer's disease : JAD. vol 26. issue 1. 2012-01-10. PMID:21593566. |
using a newly developed enzyme-linked immunosorbent assay (elisa), we measured levels of igg autoantibodies against neuronal and glial structures in serum and cerebrospinal fluid of a total of 91 subjects (13 pdd, 14 dlb, 11 alzheimer's disease (ad), 11 frontotemporal dementia (ftd), 11 vascular dementia patients (vad), and 31 healthy controls). |
2012-01-10 |
2023-08-12 |
human |
| V Camacho, M Marquié, A Lleó, L Alvés, C Artigas, A Flotats, J Duch, R Blesa, T Gómez-Isla, I Carrió, M Estorc. Cardiac sympathetic impairment parallels nigrostriatal degeneration in Probable Dementia with Lewy Bodies. The quarterly journal of nuclear medicine and molecular imaging : official publication of the Italian Association of Nuclear Medicine (AIMN) [and] the International Association of Radiopharmacology (IAR), [and] Section of the Society of.... vol 55. issue 4. 2012-01-03. PMID:21150861. |
dementia with lewy bodies (dlb) must be distinguished from other types of dementia because of important differences in patient management and outcome. |
2012-01-03 |
2023-08-12 |
Not clear |
| Mie Hirohata, Kenjiro Ono, Akiyoshi Morinaga, Tokuhei Ikeda, Masahito Yamad. Cerebrospinal fluid from patients with multiple system atrophy promotes in vitro α-synuclein fibril formation. Neuroscience letters. vol 491. issue 1. 2011-12-30. PMID:21215793. |
the aggregation of α-synuclein (αs) in the central nervous system (cns) is the hallmark of multiple system atrophy (msa) and lewy body diseases including parkinson's disease (pd) and dementia with lewy bodies (dlb) (α-synucleinopathies). |
2011-12-30 |
2023-08-12 |
Not clear |
| Harriet Quigley, Sean J Colloby, John T O'Brie. PET imaging of brain amyloid in dementia: a review. International journal of geriatric psychiatry. vol 26. issue 10. 2011-12-21. PMID:21905095. |
to review the rapidly expanding literature of amyloid pet imaging with particular attention to pittsburgh compound-b (pib) in alzheimer's disease (ad), dementia with lewy bodies (dlb), fronto-temporal dementia (ftd), mild cognitive impairment (mci) and cognitively normal volunteers. |
2011-12-21 |
2023-08-12 |
human |
| Isidro Ferrer, Ana Gómez, Margarita Carmona, Gema Huesa, Silvia Porta, Miquel Riera-Codina, Marta Biagioli, Stefano Gustincich, Ester As. Neuronal hemoglobin is reduced in Alzheimer's disease, argyrophilic grain disease, Parkinson's disease, and dementia with Lewy bodies. Journal of Alzheimer's disease : JAD. vol 23. issue 3. 2011-12-20. PMID:21157025. |
progressing with these studies, hemoglobin expression has been examined in selected cell population in the brains of alzheimer's disease (ad), argyrophilic grain disease (agd), parkinson's disease (pd) and dementia with lewy bodies (dlb). |
2011-12-20 |
2023-08-12 |
human |