Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
Mirko Bibl, Hermann Esselmann, Piotr Lewczuk, Claudia Trenkwalder, Markus Otto, Johannes Kornhuber, Jens Wiltfang, Brit Mollenhaue. Combined Analysis of CSF Tau, Aβ42, Aβ1-42% and Aβ1-40% in Alzheimer's Disease, Dementia with Lewy Bodies and Parkinson's Disease Dementia. International journal of Alzheimer's disease. vol 2010. 2011-07-14. PMID:20862375. |
we studied the diagnostic value of csf aβ42/tau versus low aβ1-42% and high aβ1-40(ox)% levels for differential diagnosis of alzheimer's disease (ad) and dementia with lewy bodies (dlb), respectively. |
2011-07-14 |
2023-08-12 |
Not clear |
Mirko Bibl, Hermann Esselmann, Piotr Lewczuk, Claudia Trenkwalder, Markus Otto, Johannes Kornhuber, Jens Wiltfang, Brit Mollenhaue. Combined Analysis of CSF Tau, Aβ42, Aβ1-42% and Aβ1-40% in Alzheimer's Disease, Dementia with Lewy Bodies and Parkinson's Disease Dementia. International journal of Alzheimer's disease. vol 2010. 2011-07-14. PMID:20862375. |
csf of 45 patients with ad, 15 with dlb, 21 with parkinson's disease dementia (pdd), and 40 nondemented disease controls (ndc) was analyzed by aβ-sds-page/immunoblot and elisas (aβ42 and tau). |
2011-07-14 |
2023-08-12 |
Not clear |
Elizabeta B Mukaetova-Ladinska, Rachael Monteith, Elaine K Perr. Cerebrospinal fluid biomarkers for dementia with lewy bodies. International journal of Alzheimer's disease. vol 2010. 2011-07-14. PMID:21048932. |
of these, 5-20% will have dementia with lewy bodies (dlb). |
2011-07-14 |
2023-08-12 |
human |
Elizabeta B Mukaetova-Ladinska, Rachael Monteith, Elaine K Perr. Cerebrospinal fluid biomarkers for dementia with lewy bodies. International journal of Alzheimer's disease. vol 2010. 2011-07-14. PMID:21048932. |
clinico-pathological studies have shown that it is the low frequency of dlb clinical core features that makes the dlb diagnosis hardly recognisable during life, and easily misdiagnosed for other forms of dementia. |
2011-07-14 |
2023-08-12 |
human |
Elizabeta B Mukaetova-Ladinska, Rachael Monteith, Elaine K Perr. Cerebrospinal fluid biomarkers for dementia with lewy bodies. International journal of Alzheimer's disease. vol 2010. 2011-07-14. PMID:21048932. |
however, a combination of csf measures appear to emerge, that may well be able to differentiate dlb from other dementias: α-synuclein reduction in early dlb, a correlation between csf α-synuclein and aβ42 measures (characteristic for dlb only), and t-tau and p-tau181 profile (differentiating ad from dlb). |
2011-07-14 |
2023-08-12 |
human |
Clive Bate, Steve Gentleman, Alun William. α-synuclein induced synapse damage is enhanced by amyloid-β1-42. Molecular neurodegeneration. vol 5. 2011-07-14. PMID:21138585. |
the pathogenesis of parkinson's disease (pd) and dementia with lewy bodies (dlb) is associated with the accumulation of aggregated forms of the α-synuclein (αsn) protein. |
2011-07-14 |
2023-08-12 |
Not clear |
Avrom L Kurtz, Daniel I Kaufe. Dementia in Parkinson's disease. Current treatment options in neurology. vol 13. issue 3. 2011-07-14. PMID:21461668. |
dementia in parkinson's disease encompasses a spectrum relating to motor, psychiatric, and cognitive symptoms that are classified as either dementia with lewy bodies (dlb) (initial cognitive symptoms) or parkinson's disease dementia (pdd) (initial motor signs preceding cognitive symptoms by at least a year). |
2011-07-14 |
2023-08-12 |
Not clear |
Kyung Won Park, Hyun Sook Kim, Sang-Myung Cheon, Jae-Kwan Cha, Sang-Ho Kim, Jae Woo Ki. Dementia with Lewy Bodies versus Alzheimer's Disease and Parkinson's Disease Dementia: A Comparison of Cognitive Profiles. Journal of clinical neurology (Seoul, Korea). vol 7. issue 1. 2011-07-14. PMID:21519522. |
it is particularly difficult to differentiate dementia with lewy bodies (dlb) from the related dementias of alzheimer's disease (ad) and parkinson's disease dementia (pdd). |
2011-07-14 |
2023-08-12 |
Not clear |
H Brunnström, N Friberg, E Lindberg, E Englun. Differential degeneration of the locus coeruleus in dementia subtypes. Clinical neuropathology. vol 30. issue 3. 2011-07-12. PMID:21545773. |
neuronal loss in the locus coeruleus (lc) is common in alzheimer's disease (ad), dementia with lewy bodies (dlb) and parkinson's disease dementia (pdd). |
2011-07-12 |
2023-08-12 |
Not clear |
Paul M Kemp, Katie Clyde, Clive Holme. Impact of 123I-FP-CIT (DaTSCAN) SPECT on the diagnosis and management of patients with dementia with Lewy bodies: a retrospective study. Nuclear medicine communications. vol 32. issue 4. 2011-06-20. PMID:21278615. |
to assess the impact of imaging the presynaptic dopaminergic terminal using datscan single-photon emission computed tomography (spect) on the clinical diagnosis and subsequent management of patients with possible dementia with lewy bodies (dlb), who were referred for imaging. |
2011-06-20 |
2023-08-12 |
Not clear |
Kengo Maeda, Nobuhiro Ogaw. Amitriptyline and lorazepam improved catatonia and occipital hypoperfusion in a patient with DLB. Internal medicine (Tokyo, Japan). vol 50. issue 4. 2011-06-14. PMID:21325773. |
she was diagnosed as probable dementia with lewy bodies (dlb). |
2011-06-14 |
2023-08-12 |
Not clear |
Dawn P Gill, Thomas D Koepsell, Rebecca A Hubbard, Walter A Kukul. Risk of decline in functional activities in dementia with Lewy bodies and Alzheimer disease. Alzheimer disease and associated disorders. vol 25. issue 1. 2011-06-08. PMID:21192240. |
we examined the risk of 1-year decline in 4 everyday activities in patients with dementia with lewy bodies (dlb), relative to patients with alzheimer disease (ad). |
2011-06-08 |
2023-08-12 |
human |
Dawn P Gill, Thomas D Koepsell, Rebecca A Hubbard, Walter A Kukul. Risk of decline in functional activities in dementia with Lewy bodies and Alzheimer disease. Alzheimer disease and associated disorders. vol 25. issue 1. 2011-06-08. PMID:21192240. |
participants (n=1880) were: aged 60+ years, demented with a primary clinical diagnosis of probable ad or dlb, and had a global clinical dementia rating of 0.5 to 2. |
2011-06-08 |
2023-08-12 |
human |
Daniel O Claassen, Val J Lowe, Patrick J Peller, Ronald C Petersen, Keith A Joseph. Amyloid and glucose imaging in dementia with Lewy bodies and multiple systems atrophy. Parkinsonism & related disorders. vol 17. issue 3. 2011-06-07. PMID:21195652. |
multiple systems atrophy (msa) and dementia with lewy bodies (dlb) can present with both rem behavior disorder and severe autonomic dysfunction. |
2011-06-07 |
2023-08-12 |
Not clear |
Satoshi Ueda, Keiko Koyama, Hiroki Kocha, Yoshiro Okub. [Dementia with Lewy bodies (DLB) accompanied by symptoms of late catatonia: what to consider and how to treat]. Seishin shinkeigaku zasshi = Psychiatria et neurologia Japonica. vol 113. issue 2. 2011-06-02. PMID:21485531. |
[dementia with lewy bodies (dlb) accompanied by symptoms of late catatonia: what to consider and how to treat]. |
2011-06-02 |
2023-08-12 |
Not clear |
Satoshi Ueda, Keiko Koyama, Hiroki Kocha, Yoshiro Okub. [Dementia with Lewy bodies (DLB) accompanied by symptoms of late catatonia: what to consider and how to treat]. Seishin shinkeigaku zasshi = Psychiatria et neurologia Japonica. vol 113. issue 2. 2011-06-02. PMID:21485531. |
dementia with lewy bodies (dlb) has recently often been reported to exhibit various psychiatric symptoms. |
2011-06-02 |
2023-08-12 |
Not clear |
Shinji Higashi, Darren J Moore, Michiko Minegishi, Koji Kasanuki, Hiroshige Fujishiro, Tomohiro Kabuta, Takashi Togo, Omi Katsuse, Hirotake Uchikado, Yoshiko Furukawa, Hiroaki Hino, Kenji Kosaka, Kiyoshi Sato, Heii Arai, Keiji Wada, Eizo Isek. Localization of MAP1-LC3 in vulnerable neurons and Lewy bodies in brains of patients with dementia with Lewy bodies. Journal of neuropathology and experimental neurology. vol 70. issue 4. 2011-05-27. PMID:21412173. |
we investigated potential neuropathologic and biochemical alterations of autophagy-lysosome pathway-related proteins in the brains of patients with dementia with lewy bodies (dlb), alzheimer disease (ad), and control subjects using antibodies against ras-related protein rab-7b (rab7b), lysosomal-associated membrane protein 2 (lamp2), and microtubule-associated protein 1a/1b light chain 3 (lc3). |
2011-05-27 |
2023-08-12 |
human |
A Golimstok, J I Rojas, M Romano, M C Zurru, D Doctorovich, E Cristian. Previous adult attention-deficit and hyperactivity disorder symptoms and risk of dementia with Lewy bodies: a case-control study. European journal of neurology. vol 18. issue 1. 2011-05-25. PMID:20491888. |
previous reports have shown that in dementia with lewy body (dlb) and attention-deficit and hyperactivity disorder (adhd) a hypodopaminergic and noradrenergic substrate seems to play a central role in developing the diseases. |
2011-05-25 |
2023-08-12 |
Not clear |
A Golimstok, J I Rojas, M Romano, M C Zurru, D Doctorovich, E Cristian. Previous adult attention-deficit and hyperactivity disorder symptoms and risk of dementia with Lewy bodies: a case-control study. European journal of neurology. vol 18. issue 1. 2011-05-25. PMID:20491888. |
we investigated the hypothesis that attention deficit may precede dlb expressed as adult adhd symptoms long before the clinical onset of dementia. |
2011-05-25 |
2023-08-12 |
Not clear |
David T R Coulson, Nancy Beyer, Joe G Quinn, Simon Brockbank, Jan Hellemans, G Brent Irvine, Rivka Ravid, Janet A Johnsto. BACE1 mRNA expression in Alzheimer's disease postmortem brain tissue. Journal of Alzheimer's disease : JAD. vol 22. issue 4. 2011-05-25. PMID:20930286. |
rna was prepared from five brain regions in three study groups: controls, individuals with ad, and another neurodegenerative disease group affected by either parkinson's disease (pd) or dementia with lewy bodies (dlb). |
2011-05-25 |
2023-08-12 |
Not clear |