| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Elizabeta B Mukaetova-Ladinska, John H Xuereb, Francisco Garcia-Sierra, Jenny Hurt, Herman-J Gertz, Richard Hills, Carol Brayne, Felicia A Huppert, Eugene S Paykel, Magnus A McGee, Ross Jakes, William G Honer, Charles R Harrington, Claude M Wischi. Lewy body variant of Alzheimer's disease: selective neocortical loss of t-SNARE proteins and loss of MAP2 and alpha-synuclein in medial temporal lobe. TheScientificWorldJournal. vol 9. 2010-02-24. PMID:20024519. |
lewy bodies (lbs) appear in the brains of nondemented individuals and also occur in a range of neurodegenerative disorders, such as dementia with lewy bodies (dlb) and parkinson's disease. |
2010-02-24 |
2023-08-12 |
human |
| Ryuichi Takahashi, Kazunari Ishii, Kenichi Shimada, Shingo Ohkawa, Yo Nishimur. Hypoperfusion of the motor cortex associated with parkinsonism in dementia with Lewy bodies. Journal of the neurological sciences. vol 288. issue 1-2. 2010-02-17. PMID:19854452. |
this study aimed to investigate the impact of parkinsonism on regional cerebral blood flow (rcbf) in dementia with lewy bodies (dlb). |
2010-02-17 |
2023-08-12 |
Not clear |
| Andrew O Koob, Kiren Ubhi, Johan F Paulsson, Jeffery Kelly, Edward Rockenstein, Michael Mante, Anthony Adame, Eliezer Maslia. Lovastatin ameliorates alpha-synuclein accumulation and oxidation in transgenic mouse models of alpha-synucleinopathies. Experimental neurology. vol 221. issue 2. 2010-02-16. PMID:19944097. |
alpha-synuclein (alpha-syn) aggregation is a neuropathological hallmark of many diseases including dementia with lewy bodies (dlb) and parkinson's disease (pd), collectively termed the alpha-synucleinopathies. |
2010-02-16 |
2023-08-12 |
mouse |
| Masaru Tateno, Seiju Kobayashi, Toshikazu Sait. Imaging improves diagnosis of dementia with lewy bodies. Psychiatry investigation. vol 6. issue 4. 2010-02-08. PMID:20140120. |
dementia with lewy bodies (dlb) is the second most common cause of degenerative dementia after alzheimer's disease (ad), and is clinically characterized by the progressive cognitive decline with fluctuations in cognition and alertness, recurrent visual hallucinations and parkinsonism. |
2010-02-08 |
2023-08-12 |
Not clear |
| Masaru Tateno, Seiju Kobayashi, Toshikazu Sait. Imaging improves diagnosis of dementia with lewy bodies. Psychiatry investigation. vol 6. issue 4. 2010-02-08. PMID:20140120. |
however, in the early disease stages, the clinical symptoms of various types of dementias largely overlap and it is difficult to distinguish dlb from other neurodegenerative dementias based on clinical manifestations alone. |
2010-02-08 |
2023-08-12 |
Not clear |
| M T Feitsma, T van Laar, P L J Dautzenber. [The possible value of diagnosing MCI-DLB and treatment options]. Tijdschrift voor gerontologie en geriatrie. vol 40. issue 4. 2010-02-02. PMID:20088343. |
dementia with lewy bodies (dlb) is a well-described clinical entity. |
2010-02-02 |
2023-08-12 |
Not clear |
| Carlo Rossi, Duccio Volterrani, Valentina Nicoletti, Gianpiero Manca, Daniela Frosini, Lorenzo Kiferle, Elisa Unti, Paola De Feo, Ubaldo Bonuccelli, Roberto Ceravol. "Parkinson-dementia" diseases: a comparison by double tracer SPECT studies. Parkinsonism & related disorders. vol 15. issue 10. 2010-01-27. PMID:19553153. |
we performed 123i-fp-cit/spect and ecd/spect in 30 patients with parkinson's disease with dementia (pdd) and 30 patients with dementia with lewy bodies (dlb) to evaluate whether presynaptic nigro-striatal function and/or cerebral perfusional pattern is different in these diseases. |
2010-01-27 |
2023-08-12 |
Not clear |
| Fredrik Boström, Oskar Hansson, Kaj Blennow, Lars Gerhardsson, Thomas Lundh, Lennart Minthon, Henrik Zetterberg, Elisabet Londo. Cerebrospinal fluid total tau is associated with shorter survival in dementia with Lewy bodies. Dementia and geriatric cognitive disorders. vol 28. issue 4. 2010-01-26. PMID:19844105. |
a pathology typical of dementia with lewy bodies (dlb) has been demonstrated to increase mortality to a greater extent than the pathology of alzheimer's disease (ad). |
2010-01-26 |
2023-08-12 |
human |
| Martin Köllensperger, Gregor K Wennin. Assessing disease progression with MRI in atypical parkinsonian disorders. Movement disorders : official journal of the Movement Disorder Society. vol 24 Suppl 2. 2010-01-26. PMID:19877233. |
the article reviews the current state of the art focusing on three atypical parkinsonian disorders: multiple system atrophy (msa), progressive supranuclear palsy (psp), and dementia with lewy bodies (dlb). |
2010-01-26 |
2023-08-12 |
Not clear |
| Rodney W H Walker, Zuzana Walke. Dopamine transporter single photon emission computerized tomography in the diagnosis of dementia with Lewy bodies. Movement disorders : official journal of the Movement Disorder Society. vol 24 Suppl 2. 2010-01-26. PMID:19877236. |
dementia with lewy bodies (dlb) is part of the spectrum of lewy body disorders. |
2010-01-26 |
2023-08-12 |
Not clear |
| David J Brook. Imaging amyloid in Parkinson's disease dementia and dementia with Lewy bodies with positron emission tomography. Movement disorders : official journal of the Movement Disorder Society. vol 24 Suppl 2. 2010-01-26. PMID:19877240. |
although parkinson's disease with later dementia (pdd) and dementia with lewy bodies (dlb) are pathologically characterized by the presence of intraneuronal lewy inclusion bodies, amyloid deposition is also associated to varying degrees with both these disorders. |
2010-01-26 |
2023-08-12 |
Not clear |
| David J Brook. Imaging amyloid in Parkinson's disease dementia and dementia with Lewy bodies with positron emission tomography. Movement disorders : official journal of the Movement Disorder Society. vol 24 Suppl 2. 2010-01-26. PMID:19877240. |
anti-amyloid strategies could be a relevant approach for slowing dementia in a number of dlb and pdd cases. |
2010-01-26 |
2023-08-12 |
Not clear |
| Seigo Nakano, Hiroshi Matsud. [Brain functional imaging of frontotemporal lobar degeneration]. Brain and nerve = Shinkei kenkyu no shinpo. vol 61. issue 11. 2010-01-21. PMID:19938684. |
regionally distinct patterns of hypoperfusion on single-photon emission computed tomography (spect) or hypometabolism on positron emission tomography (pet) are helpful in differentiation of ftld, alzheimer's disease (ad), dementia with lewy bodies (dlb), and corticobasal degeneration (cbd). |
2010-01-21 |
2023-08-12 |
Not clear |
| Leena Aho, Kari Karkola, Jari Juusela, Irina Alafuzof. Heavy alcohol consumption and neuropathological lesions: a post-mortem human study. Journal of neuroscience research. vol 87. issue 12. 2010-01-12. PMID:19382227. |
the present study evaluated the association between heavy alcohol intake and the neuropathological hallmark lesions of the three most common neurodegenerative disorders, i.e., alzheimer's disease (ad), dementia with lewy bodies (dlb), and vascular cognitive impairment (vci), in post-mortem human brains. |
2010-01-12 |
2023-08-12 |
human |
| Leena Aho, Kari Karkola, Jari Juusela, Irina Alafuzof. Heavy alcohol consumption and neuropathological lesions: a post-mortem human study. Journal of neuroscience research. vol 87. issue 12. 2010-01-12. PMID:19382227. |
our results indicate that alcohol-related dementia differs from vci, ad, and dlb; i.e., it has a different etiology and pathogenesis. |
2010-01-12 |
2023-08-12 |
human |
| Francesco Roselli, Nicola M Pisciotta, Robert Perneczky, Michele Pennelli, Maria S Aniello, Maria F De Caro, Ermanno Ferrannini, Bruno Tartaglione, Giovanni Defazio, Giuseppe Rubini, Paolo Livre. Severity of neuropsychiatric symptoms and dopamine transporter levels in dementia with Lewy bodies: a 123I-FP-CIT SPECT study. Movement disorders : official journal of the Movement Disorder Society. vol 24. issue 14. 2010-01-12. PMID:19705471. |
neuropsychiatric symptoms are frequent in dementia with lewy bodies (dlb). |
2010-01-12 |
2023-08-12 |
Not clear |
| Agnes Fehér, Anna Juhász, Agnes Rimanóczy, János Kálmán, Zoltán Jank. Association between BDNF Val66Met polymorphism and Alzheimer disease, dementia with Lewy bodies, and Pick disease. Alzheimer disease and associated disorders. vol 23. issue 3. 2010-01-08. PMID:19812463. |
apolipoprotein e (apoe) gene polymorphism is known to be associated with alzheimer disease (ad), dementia with lewy bodies (dlb), and pick disease (pid). |
2010-01-08 |
2023-08-12 |
Not clear |
| Jianshe Wei, Masayo Fujita, Akio Sekigawa, Kazunari Sekiyama, Masaaki Waragai, Makoto Hashimot. Gangliosides' protection against lysosomal pathology of synucleinopathies. Autophagy. vol 5. issue 6. 2010-01-06. PMID:19458475. |
in our recent publication, dementia with lewy bodies (dlb)-linked neuroblastoma cells were treated with d-threo-1-phenyl-2-decanoylamino-3-morpholino-1-propanol (pdmp), an inhibitor of glycosyl ceramide synthetase. |
2010-01-06 |
2023-08-12 |
Not clear |
| Seiju Kobayashi, Masaru Tateno, Hidetoshi Morii, Kumiko Utsumi, Toshikazu Sait. Decreased cardiac MIBG uptake, its correlation with clinical symptoms in dementia with Lewy bodies. Psychiatry research. vol 174. issue 1. 2009-12-29. PMID:19766460. |
recent studies have demonstrated the usefulness of 123i-meta-iodobenzylguanidine (mibg) myocardial scintigraphy for the diagnosis of dementia with lewy bodies (dlb). |
2009-12-29 |
2023-08-12 |
human |
| R Armstrong, N Cairns, P Lanto. The spatial patterns of Pick bodies, Pick cells and Alzheimer's disease pathology in Pick's disease. Neuropathology : official journal of the Japanese Society of Neuropathology. vol 19. issue 1. 2009-12-15. PMID:19519649. |
the data suggest that pb and pc in patients with pd exhibit essentially the same spatial patterns as sp and nft in alzheimer's disease (ad) and lewy bodies (lb) in dementia with lewy bodies (dlb). |
2009-12-15 |
2023-08-12 |
Not clear |