| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Olivier Piguet, Glenda M Halliday, Helen Creasey, G Anthony Broe, Jillian J Kri. Frontotemporal dementia and dementia with Lewy bodies in a case-control study of Alzheimer's disease. International psychogeriatrics. vol 21. issue 4. 2009-09-17. PMID:19493380. |
the clinical presentations in dementia with lewy bodies (dlb) and frontotemporal dementia (ftd) overlap considerably with that of alzheimer's disease (ad) despite different pathological processes. |
2009-09-17 |
2023-08-12 |
Not clear |
| H Shimada, S Hirano, H Shinotoh, A Aotsuka, K Sato, N Tanaka, T Ota, M Asahina, K Fukushi, S Kuwabara, T Hattori, T Suhara, T Iri. Mapping of brain acetylcholinesterase alterations in Lewy body disease by PET. Neurology. vol 73. issue 4. 2009-09-09. PMID:19474411. |
to characterize brain cholinergic deficits in parkinson disease (pd), pd with dementia (pdd), and dementia with lewy bodies (dlb). |
2009-09-09 |
2023-08-12 |
Not clear |
| Karen Koopman, Nathalie Le Bastard, Jean-Jacques Martin, Guy Nagels, Peter P De Deyn, Sebastiaan Engelborgh. Improved discrimination of autopsy-confirmed Alzheimer's disease (AD) from non-AD dementias using CSF P-tau(181P). Neurochemistry international. vol 55. issue 4. 2009-09-02. PMID:19524111. |
optimal p-tau(181p) cut-off levels for differentiating ad from pooled non-ad dementias, dementia with lewy bodies (dlb) and frontotemporal dementia (ftd) were 50.4pg/ml (acc=0.73), 52.8pg/ml (acc=0.73) and 35.3pg/ml (acc=0.90), respectively. |
2009-09-02 |
2023-08-12 |
Not clear |
| Fredrik Boström, Oskar Hansson, Lars Gerhardsson, Thomas Lundh, Lennart Minthon, Erik Stomrud, Henrik Zetterberg, Elisabet Londo. CSF Mg and Ca as diagnostic markers for dementia with Lewy bodies. Neurobiology of aging. vol 30. issue 8. 2009-08-31. PMID:18191875. |
however, few investigations have addressed this issue in dementia with lewy bodies (dlb). |
2009-08-31 |
2023-08-12 |
human |
| Kurt A Jellinge. A critical evaluation of current staging of alpha-synuclein pathology in Lewy body disorders. Biochimica et biophysica acta. vol 1792. issue 7. 2009-08-25. PMID:18718530. |
the two most frequent synucleinopathies, parkinson disease (pd) or brainstem predominant type of lewy body disease, and dementia with lewy bodies (dlb), are neurodegenerative multisystem disorders with widespread occurrence of alpha-synuclein containing deposits in the central, peripheral, and autonomic systems. |
2009-08-25 |
2023-08-12 |
human |
| Kurt A Jellinge. A critical evaluation of current staging of alpha-synuclein pathology in Lewy body disorders. Biochimica et biophysica acta. vol 1792. issue 7. 2009-08-25. PMID:18718530. |
there is considerable clinical and pathologic overlap between pd (with or without dementia) and dlb, corresponding to braak lb stages 5 and 6, both frequently associated with variable alzheimer-type pathology. |
2009-08-25 |
2023-08-12 |
human |
| M E Kalaitzakis, R K B Pearce, S M Gentlema. Clinical correlates of pathology in the claustrum in Parkinson's disease and dementia with Lewy bodies. Neuroscience letters. vol 461. issue 1. 2009-08-24. PMID:19523504. |
we studied alpha-synuclein (alphasyn), tau and amyloid-beta (abeta) pathology in the claustrum of 20 pd cases without dementia, 12 pd cases with dementia (pdd) and 7 cases with dementia with lewy bodies (dlb). |
2009-08-24 |
2023-08-12 |
Not clear |
| M E Kalaitzakis, R K B Pearce, S M Gentlema. Clinical correlates of pathology in the claustrum in Parkinson's disease and dementia with Lewy bodies. Neuroscience letters. vol 461. issue 1. 2009-08-24. PMID:19523504. |
alphasyn positivity was observed in 75% of pd cases without dementia and in 100% of pdd and dlb cases. |
2009-08-24 |
2023-08-12 |
Not clear |
| M E Kalaitzakis, R K B Pearce, S M Gentlema. Clinical correlates of pathology in the claustrum in Parkinson's disease and dementia with Lewy bodies. Neuroscience letters. vol 461. issue 1. 2009-08-24. PMID:19523504. |
in addition, dlb cases showed a significantly increased alphasyn deposition when compared to pdd (p=0.02) and pd without dementia (p=0.0002). |
2009-08-24 |
2023-08-12 |
Not clear |
| M E Kalaitzakis, R K B Pearce, S M Gentlema. Clinical correlates of pathology in the claustrum in Parkinson's disease and dementia with Lewy bodies. Neuroscience letters. vol 461. issue 1. 2009-08-24. PMID:19523504. |
we demonstrate that pathology in the claustrum, a region of largely obscure physiological function, strongly relates to the presence of dementia in parkinson's disease and dlb. |
2009-08-24 |
2023-08-12 |
Not clear |
| Philip Schelten. Imaging in Alzheimer's disease. Dialogues in clinical neuroscience. vol 11. issue 2. 2009-08-20. PMID:19585954. |
from being used for exclusive purposes only, neuroimaging is now in the forefront of aiding in the diagnosis of alzheimer's disease (ad), frontotemporal dementia, vascular dementia, and and dementia with lewy bodies (dlb). |
2009-08-20 |
2023-08-12 |
Not clear |
| Philip Schelten. Imaging in Alzheimer's disease. Dialogues in clinical neuroscience. vol 11. issue 2. 2009-08-20. PMID:19585954. |
with the exception of dopamine transporter single photon-emission computed tomography imaging in dlb, imaging has not yet been incorporated into the diagnostic criteria for the various dementia syndromes, but that will soon change. |
2009-08-20 |
2023-08-12 |
Not clear |
| L Parnetti, C Balducci, L Pierguidi, C De Carlo, M Peducci, C D'Amore, C Padiglioni, S Mastrocola, E Persichetti, S Paciotti, G Bellomo, N Tambasco, A Rossi, T Beccari, P Calabres. Cerebrospinal fluid beta-glucocerebrosidase activity is reduced in Dementia with Lewy Bodies. Neurobiology of disease. vol 34. issue 3. 2009-08-17. PMID:19303930. |
clinical and genetic studies indicate that mutations of beta-glucocerebrosidase represent genetic risk factors for synucleinopathies, including parkinson's disease (pd) and dementia with lewy bodies (dlb). |
2009-08-17 |
2023-08-12 |
Not clear |
| L Parnetti, C Balducci, L Pierguidi, C De Carlo, M Peducci, C D'Amore, C Padiglioni, S Mastrocola, E Persichetti, S Paciotti, G Bellomo, N Tambasco, A Rossi, T Beccari, P Calabres. Cerebrospinal fluid beta-glucocerebrosidase activity is reduced in Dementia with Lewy Bodies. Neurobiology of disease. vol 34. issue 3. 2009-08-17. PMID:19303930. |
we have thus measured the activity of these enzymes - alpha-mannosidase (ec 3.2.1.24), beta-mannosidase (ec 3.2.1.25), beta-glucocerebrosidase (ec 3.2.1.45), beta-galactosidase (ec 3.2.1.23) and beta-hexosaminidase (ec 3.2.1.52) - in cerebrospinal fluid of patients suffering from dlb, alzheimer's disease (ad), fronto-temporal dementia (ftd) and controls. |
2009-08-17 |
2023-08-12 |
Not clear |
| Y Akaogi, M Asahina, Y Yamanaka, Y Koyama, T Hattor. Sudomotor, skin vasomotor, and cardiovascular reflexes in 3 clinical forms of Lewy body disease. Neurology. vol 73. issue 1. 2009-08-17. PMID:19564585. |
to elucidate the differences among dementia with lewy bodies (dlb), parkinson disease with dementia (pdd), and parkinson disease without dementia (pd), with respect to the involvement of the autonomic nervous system, we clinically investigated the cutaneous and cardiovascular autonomic functions in patients with lewy body disease. |
2009-08-17 |
2023-08-12 |
Not clear |
| Dag Aarsland, Clive Ballard, Zuzana Walker, Fredrik Bostrom, Guido Alves, Katja Kossakowski, Iracema Leroi, Francisco Pozo-Rodriguez, Lennart Minthon, Elisabet Londo. Memantine in patients with Parkinson's disease dementia or dementia with Lewy bodies: a double-blind, placebo-controlled, multicentre trial. The Lancet. Neurology. vol 8. issue 7. 2009-08-14. PMID:19520613. |
dementia with lewy bodies (dlb) and parkinson's disease dementia (pdd) are common forms of dementia that substantially affect quality of life. |
2009-08-14 |
2023-08-12 |
Not clear |
| Jennifer C Hanson, Carol F Lipp. Lewy body dementia. International review of neurobiology. vol 84. 2009-08-12. PMID:19501720. |
dementia with lewy bodies (dlb) is thought to be the second most common subtype. |
2009-08-12 |
2023-08-12 |
Not clear |
| Jennifer C Hanson, Carol F Lipp. Lewy body dementia. International review of neurobiology. vol 84. 2009-08-12. PMID:19501720. |
the clinical features of dlb are strikingly similar to those of dementia in parkinson's disease (pd). |
2009-08-12 |
2023-08-12 |
Not clear |
| Jennifer C Hanson, Carol F Lipp. Lewy body dementia. International review of neurobiology. vol 84. 2009-08-12. PMID:19501720. |
pd dementia shares these pathological findings with dlb, as well as neural degeneration of the substantia nigra. |
2009-08-12 |
2023-08-12 |
Not clear |
| Jennifer C Hanson, Carol F Lipp. Lewy body dementia. International review of neurobiology. vol 84. 2009-08-12. PMID:19501720. |
dlb and dementia in pd may represent the same pathological process along a disease spectrum. |
2009-08-12 |
2023-08-12 |
Not clear |