| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Alain Robillar. Clinical diagnosis of dementia. Alzheimer's & dementia : the journal of the Alzheimer's Association. vol 3. issue 4. 2009-12-14. PMID:19595950. |
the separation of lewy body dementia (dlb) from parkinson's disease dementia (pdd) is based on the dominant clinical presenting feature of each syndrome, and relies on the duration of this feature: long duration of parkinsonian "motor" syndrome preceding dementia for pdd versus early/initial dementia accompanied by extrapyramidal symptoms for dlb. |
2009-12-14 |
2023-08-12 |
Not clear |
| Kurt A Jellinge. Formation and development of Lewy pathology: a critical update. Journal of neurology. vol 256 Suppl 3. 2009-12-11. PMID:19711116. |
filamentous protein inclusions in neurons (lewy bodies, lb) and dystrophic neurites containing pathologic alpha-synuclein (alpha syn) are the morphologic hallmarks of sporadic parkinson disease (pd) and dementia with lewy bodies (dlb), but are also found in aged subjects and in a variety of neurogenerative disorders. |
2009-12-11 |
2023-08-12 |
human |
| Paul T Franci. Biochemical and pathological correlates of cognitive and behavioural change in DLB/PDD. Journal of neurology. vol 256 Suppl 3. 2009-12-11. PMID:19711117. |
dementia with lewy bodies (dlb) and parkinson's disease dementia (pdd) are second only to alzheimer's disease (ad) in frequency. |
2009-12-11 |
2023-08-12 |
Not clear |
| Masayo Fujita, Akio Sekigawa, Kazunari Sekiyama, Shuei Sugama, Makoto Hashimot. Neurotoxic conversion of beta-synuclein: a novel approach to generate a transgenic mouse model of synucleinopathies? Journal of neurology. vol 256 Suppl 3. 2009-12-11. PMID:19711118. |
many groups have generated alpha-synuclein (alpha-syn) transgenic (tg) mice as a rodent model for human synucleinopathies, including parkinson's disease and dementia with lewy bodies (dlb). |
2009-12-11 |
2023-08-12 |
mouse |
| Cristina Sanchez-Castaneda, Ramon Rene, Blanca Ramirez-Ruiz, Jaume Campdelacreu, Jordi Gascon, Carles Falcon, Matilde Calopa, Serge Jauma, Montserrat Juncadella, Carme Junqu. Correlations between gray matter reductions and cognitive deficits in dementia with Lewy Bodies and Parkinson's disease with dementia. Movement disorders : official journal of the Movement Disorder Society. vol 24. issue 12. 2009-12-04. PMID:19569130. |
there is controversy regarding whether dementia with lewy bodies (dlb) and parkinson's disease with dementia (pdd) may or not be different manifestations of the same disorder. |
2009-12-04 |
2023-08-12 |
human |
| Ryuichi Harada, Natsuki Kobayashi, Jihoon Kim, Chikashi Nakamura, Sung-Woong Han, Kazunori Ikebukuro, Koji Sod. The effect of amino acid substitution in the imperfect repeat sequences of alpha-synuclein on fibrillation. Biochimica et biophysica acta. vol 1792. issue 10. 2009-11-25. PMID:19596443. |
human alpha-synuclein is the causative protein of several neurodegenerative diseases, such as parkinson's disease (pd) and dementia with lewy bodies (dlb). |
2009-11-25 |
2023-08-12 |
human |
| Agnes Fehér, Anna Juhász, Agnes Rimanóczy, Eva Csibri, János Kálmán, Zoltán Jank. Association between a genetic variant of the alpha-7 nicotinic acetylcholine receptor subunit and four types of dementia. Dementia and geriatric cognitive disorders. vol 28. issue 1. 2009-11-16. PMID:19641318. |
we tested the hypothesis whether the partially duplicated variant of alpha7 nicotinic acetylcholine receptor subunit gene (chrfam7a) 2-bp deletion (-2 bp) polymorphism and apolipoprotein e (apoe) epsilon4 allele confer susceptibility to alzheimer's disease (ad), dementia with lewy bodies (dlb), pick's disease (pid) and vascular dementia (vd). |
2009-11-16 |
2023-08-12 |
Not clear |
| Seok Ming Lim, Andrew Katsifis, Victor L Villemagne, Rene Best, Gareth Jones, Michael Saling, Jennifer Bradshaw, John Merory, Michael Woodward, Malcolm Hopwood, Christopher C Row. The 18F-FDG PET cingulate island sign and comparison to 123I-beta-CIT SPECT for diagnosis of dementia with Lewy bodies. Journal of nuclear medicine : official publication, Society of Nuclear Medicine. vol 50. issue 10. 2009-11-03. PMID:19759102. |
neuroimaging is increasingly used to supplement the clinical diagnosis of dementia with lewy bodies (dlb) by showing reduced occipital metabolism and perfusion and reduced striatal dopaminergic innervation. |
2009-11-03 |
2023-08-12 |
Not clear |
| Haruhiko Oda, Yasuji Yamamoto, Kiyoshi Maed. The neuropsychological profile in dementia with Lewy bodies and Alzheimer's disease. International journal of geriatric psychiatry. vol 24. issue 2. 2009-11-02. PMID:18615776. |
to demonstrate the exact nature of the cognitive profile of dementia with lewy bodies (dlb) on standardized neuropsychological tests including the wechsler adult intelligence scale--revised (wais-r) and the wechsler memory scale--revised (wms-r). |
2009-11-02 |
2023-08-12 |
Not clear |
| P T Nelson, R J Kryscio, G A Jicha, E L Abner, F A Schmitt, L O Xu, G Cooper, C D Smith, W R Markesber. Relative preservation of MMSE scores in autopsy-proven dementia with Lewy bodies. Neurology. vol 73. issue 14. 2009-10-30. PMID:19805729. |
recent studies raised questions about the severity of cognitive impairment associated with dementia with lewy bodies (dlb). |
2009-10-30 |
2023-08-12 |
Not clear |
| Paul Edison, David J Brooks, Federico E Turkheimer, Hilary A Archer, Rainer Hin. Strategies for the generation of parametric images of [11C]PIB with plasma input functions considering discriminations and reproducibility. NeuroImage. vol 48. issue 2. 2009-10-28. PMID:19591948. |
however the observed signal difference in other forms of dementia such as dementia with lewy bodies (dlb) is smaller, and mild cognitively impaired (mci) subjects and some healthy elderly normals may show intermediate levels of [11c]pib binding. |
2009-10-28 |
2023-08-12 |
human |
| Monica Ricci, Silvia Vittoria Guidoni, Micaela Sepe-Monti, Giuseppe Bomboi, Giovanni Antonini, Carlo Blundo, Franco Giubile. Clinical findings, functional abilities and caregiver distress in the early stage of dementia with Lewy bodies (DLB) and Alzheimer's disease (AD). Archives of gerontology and geriatrics. vol 49. issue 2. 2009-10-15. PMID:19084284. |
clinical findings, functional abilities and caregiver distress in the early stage of dementia with lewy bodies (dlb) and alzheimer's disease (ad). |
2009-10-15 |
2023-08-12 |
human |
| Sho Takahashi, Katsuyoshi Mizukami, Fumihiko Yasuno, Takashi Asad. Depression associated with dementia with Lewy bodies (DLB) and the effect of somatotherapy. Psychogeriatrics : the official journal of the Japanese Psychogeriatric Society. vol 9. issue 2. 2009-10-13. PMID:19604326. |
depression associated with dementia with lewy bodies (dlb) and the effect of somatotherapy. |
2009-10-13 |
2023-08-12 |
Not clear |
| Sho Takahashi, Katsuyoshi Mizukami, Fumihiko Yasuno, Takashi Asad. Depression associated with dementia with Lewy bodies (DLB) and the effect of somatotherapy. Psychogeriatrics : the official journal of the Japanese Psychogeriatric Society. vol 9. issue 2. 2009-10-13. PMID:19604326. |
dementia with lewy bodies (dlb) is a common type of dementia. |
2009-10-13 |
2023-08-12 |
Not clear |
| Haruhiko Oda, Yasuji Yamamoto, Kiyoshi Maed. Neuropsychological profile of dementia with Lewy bodies. Psychogeriatrics : the official journal of the Japanese Psychogeriatric Society. vol 9. issue 2. 2009-10-13. PMID:19604331. |
dementia with lewy bodies (dlb) accounts for 10-25% of all dementia cases in clinical populations and is considered to be the second most common degenerative dementia in elderly people after alzheimer's disease (ad). |
2009-10-13 |
2023-08-12 |
Not clear |
| Osamu Yokot. Frontotemporal lobar degeneration and dementia with Lewy bodies: clinicopathological issues associated with antemortem diagnosis. Psychogeriatrics : the official journal of the Japanese Psychogeriatric Society. vol 9. issue 2. 2009-10-13. PMID:19604332. |
currently, the clinical diagnostic criteria of frontotemporal lobar degeneration (ftld) and dementia with lewy bodies (dlb) are well known to neurologists and psychiatrists. |
2009-10-13 |
2023-08-12 |
Not clear |
| Robert Perneczky, Alexander Drzezga, Henning Boecker, Stefan Wagenpfeil, Hans Förstl, Alexander Kurz, Peter Häusserman. Right prefrontal hypometabolism predicts delusions in dementia with Lewy bodies. Neurobiology of aging. vol 30. issue 9. 2009-10-09. PMID:18255191. |
delusions (del) are frequent in dementia with lewy bodies (dlb); however, the neural equivalent is poorly understood. |
2009-10-09 |
2023-08-12 |
Not clear |
| Elisabetta Farina, Francesca Baglio, Paolo Caffarra, Giuseppe Magnani, Elio Scarpini, Ildebrando Appollonio, Cristina Bascelli, Antonella Cheldi, Raffaello Nemni, Massimo Franceschi, G Messa, F Mantovani, M Bellotti, F Olivotto, M Alberoni, V Isella, R Regazzoni, E Schiatti, C Vismara, M Falautano, A Barbieri, I Restelli, V Fetoni, M Donato, M Zuffi, S Castiglion. Frequency and clinical features of Lewy body dementia in Italian memory clinics. Acta bio-medica : Atenei Parmensis. vol 80. issue 1. 2009-10-08. PMID:19705622. |
the latest developments in lewy body dementia (dlb) raise some controversies on clinical features, neuroimaging and therapy. |
2009-10-08 |
2023-08-12 |
Not clear |
| Katerina E Paleologou, Christine L Kragh, David M A Mann, Sultan A Salem, Rania Al-Shami, David Allsop, Ahmed H Hassan, Poul H Jensen, Omar M A El-Agna. Detection of elevated levels of soluble alpha-synuclein oligomers in post-mortem brain extracts from patients with dementia with Lewy bodies. Brain : a journal of neurology. vol 132. issue Pt 4. 2009-10-01. PMID:19155272. |
a number of neurodegenerative diseases including parkinson's disease, dementia with lewy bodies (dlb) and multiple system atrophy are characterized by the formation and intraneuronal accumulation of fibrillar aggregates of alpha-synuclein (alpha-syn) protein in affected brain regions. |
2009-10-01 |
2023-08-12 |
human |
| Ana Navarro, Alberto Boveris, Manuel J Bández, María Jesús Sánchez-Pino, Carmen Gómez, Gerard Muntané, Isidro Ferre. Human brain cortex: mitochondrial oxidative damage and adaptive response in Parkinson disease and in dementia with Lewy bodies. Free radical biology & medicine. vol 46. issue 12. 2009-09-17. PMID:19298851. |
frontal cortex samples from frozen human brains were used to assess tissue respiration; content of mitochondria; mitochondrial oxygen uptake; activity of respiratory complexes and of mitochondrial nitric oxide synthase (mtnos); content of cytochromes a, b, and c; oxidative damage (protein carbonyls and tbars); and expression of mn-sod in patients with parkinson disease (pd) and with dementia with lewy bodies (dlb) in comparison with those of normal healthy controls. |
2009-09-17 |
2023-08-12 |
human |