| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Kensaku Kasuga, Takeshi Ikeuch. [Cerebrospinal fluid and plasma biomarkers for dementia with lewy bodies]. Brain and nerve = Shinkei kenkyu no shinpo. vol 64. issue 5. 2012-07-17. PMID:22570064. |
dementia with lewy bodies (dlb) is the second most common cause of neurodegenerative dementia in the elderly. |
2012-07-17 |
2023-08-12 |
Not clear |
| Kensaku Kasuga, Takeshi Ikeuch. [Cerebrospinal fluid and plasma biomarkers for dementia with lewy bodies]. Brain and nerve = Shinkei kenkyu no shinpo. vol 64. issue 5. 2012-07-17. PMID:22570064. |
we have previously reported that the α-synuclein levels in cerebrospinal fluid (csf) are significantly lower in patients with dlb than in patients with other types of dementia. |
2012-07-17 |
2023-08-12 |
Not clear |
| Kelvin C Luk, Victoria M Kehm, Bin Zhang, Patrick O'Brien, John Q Trojanowski, Virginia M Y Le. Intracerebral inoculation of pathological α-synuclein initiates a rapidly progressive neurodegenerative α-synucleinopathy in mice. The Journal of experimental medicine. vol 209. issue 5. 2012-07-16. PMID:22508839. |
however, the factors that trigger aggregation of α-synuclein (α-syn), the principal component of the intraneuronal inclusions known as lewy bodies (lbs), and lewy neurites (lns), which characterize parkinson's disease (pd) and dementia with lbs (dlb), are poorly understood. |
2012-07-16 |
2023-08-12 |
mouse |
| L Warr, Z Walke. Identification of biomarkers in Lewy-body disorders. The quarterly journal of nuclear medicine and molecular imaging : official publication of the Italian Association of Nuclear Medicine (AIMN) [and] the International Association of Radiopharmacology (IAR), [and] Section of the Society of.... vol 56. issue 1. 2012-07-05. PMID:22460159. |
dementia with lewy bodies (dlb) may account for up to 30% of all dementia cases. |
2012-07-05 |
2023-08-12 |
Not clear |
| L Warr, Z Walke. Identification of biomarkers in Lewy-body disorders. The quarterly journal of nuclear medicine and molecular imaging : official publication of the Italian Association of Nuclear Medicine (AIMN) [and] the International Association of Radiopharmacology (IAR), [and] Section of the Society of.... vol 56. issue 1. 2012-07-05. PMID:22460159. |
the symptoms of dlb can be difficult to disentangle from other dementia subtypes, particularly alzheimer's disease (ad). |
2012-07-05 |
2023-08-12 |
Not clear |
| L Warr, Z Walke. Identification of biomarkers in Lewy-body disorders. The quarterly journal of nuclear medicine and molecular imaging : official publication of the Italian Association of Nuclear Medicine (AIMN) [and] the International Association of Radiopharmacology (IAR), [and] Section of the Society of.... vol 56. issue 1. 2012-07-05. PMID:22460159. |
like dlb, parkinson's disease dementia (pdd) also shares common features with dlb. |
2012-07-05 |
2023-08-12 |
Not clear |
| Sharon Ash, Corey McMillan, Rachel G Gross, Philip Cook, Delani Gunawardena, Brianna Morgan, Ashley Boller, Andrew Siderowf, Murray Grossma. Impairments of speech fluency in Lewy body spectrum disorder. Brain and language. vol 120. issue 3. 2012-07-03. PMID:22099969. |
we assessed the speech production of 35 patients with lewy body spectrum disorder (lbsd), including non-demented pd patients, patients with pd dementia (pdd), and patients with dementia with lewy bodies (dlb), in a semi-structured narrative speech sample in order to characterize impairments of speech fluency and to determine the factors contributing to reduced speech fluency in these patients. |
2012-07-03 |
2023-08-12 |
Not clear |
| Namrta Sinha, Michael Firbank, John T O'Brie. Biomarkers in dementia with Lewy bodies: a review. International journal of geriatric psychiatry. vol 27. issue 5. 2012-06-28. PMID:21721045. |
dementia with lewy bodies (dlb) shares common clinical, neuropsychological and pathological features with other dementia subtypes, such as alzheimer's disease (ad), making it difficult to differentiate in clinical practice. |
2012-06-28 |
2023-08-12 |
Not clear |
| Namrta Sinha, Michael Firbank, John T O'Brie. Biomarkers in dementia with Lewy bodies: a review. International journal of geriatric psychiatry. vol 27. issue 5. 2012-06-28. PMID:21721045. |
our aim was to review the literature to identify potential biomarkers that may distinguish dlb from other dementia subtypes, especially ad. |
2012-06-28 |
2023-08-12 |
Not clear |
| Maria Carmela Tartaglia, David Y Johnson, Julie Ngoc Thai, Tatiana Cattaruzza, Katherine Wong, Paul Garcia, Stephen J Dearmond, Bruce L Miller, Michael D Geschwin. Clinical overlap between Jakob-Creutzfeldt disease and Lewy body disease. The Canadian journal of neurological sciences. Le journal canadien des sciences neurologiques. vol 39. issue 3. 2012-06-22. PMID:22547509. |
sporadic jakob-creutzfeldt disease (scjd) and dementia with lewy bodies (dlb) have overlapping clinical symptoms that can lead to their misdiagnosis. |
2012-06-22 |
2023-08-12 |
Not clear |
| Tomoyuki Miyamot. [Olfactory dysfunction in Parkinson disease and REM sleep behavior disorder]. Brain and nerve = Shinkei kenkyu no shinpo. vol 64. issue 4. 2012-06-21. PMID:22481508. |
rem sleep behavior disorder (rbd) is indicative of the development of neurodegenerative diseases involving synuclein pathology, including pd, multiple system atrophy, and dementia with lewy bodies (dlb). |
2012-06-21 |
2023-08-12 |
human |
| Satoshi Orim. [The clinical significance of MIBG myocardial scintigraphy in Parkinson disease]. Brain and nerve = Shinkei kenkyu no shinpo. vol 64. issue 4. 2012-06-21. PMID:22481513. |
reduced cardiac mibg uptake on mibg myocardial scintigraphy has been reported in patients with parkinson disease (pd), dementia with lewy bodies (dlb), pure autonomic failure (paf), and familial pd linked to snca duplication. |
2012-06-21 |
2023-08-12 |
Not clear |
| Yuko Saito, Shigeo Murayam. [Braak's hypothesis and non-motor symptoms of Parkinson disease]. Brain and nerve = Shinkei kenkyu no shinpo. vol 64. issue 4. 2012-06-21. PMID:22481517. |
if dementia precedes or occurs less than 1 year after the onset of parkinsonism, a diagnosis of dementia with lewy bodies (dlb) is made. |
2012-06-21 |
2023-08-12 |
Not clear |
| Nikolaos D Papathanasiou, Anastasios Boutsiadis, John Dickson, Jamshed B Bomanj. Diagnostic accuracy of ¹²³I-FP-CIT (DaTSCAN) in dementia with Lewy bodies: a meta-analysis of published studies. Parkinsonism & related disorders. vol 18. issue 3. 2012-06-19. PMID:21975260. |
a systematic meta-analysis of published studies on the diagnostic accuracy of presynaptic dopaminergic imaging with ¹²³i-fp-cit (datscan) in dementia with lewy bodies (dlb). |
2012-06-19 |
2023-08-12 |
Not clear |
| Michal Rolinski, Chris Fox, Ian Maidment, Rupert McShan. Cholinesterase inhibitors for dementia with Lewy bodies, Parkinson's disease dementia and cognitive impairment in Parkinson's disease. The Cochrane database of systematic reviews. issue 3. 2012-06-07. PMID:22419314. |
previous cochrane reviews have considered the use of cholinesterase inhibitors in both parkinson's disease with dementia (pdd) and dementia with lewy bodies (dlb). |
2012-06-07 |
2023-08-12 |
Not clear |
| Michal Rolinski, Chris Fox, Ian Maidment, Rupert McShan. Cholinesterase inhibitors for dementia with Lewy bodies, Parkinson's disease dementia and cognitive impairment in Parkinson's disease. The Cochrane database of systematic reviews. issue 3. 2012-06-07. PMID:22419314. |
the clinical features of dlb and pdd have much in common and are distinguished primarily on the basis of whether or not parkinsonism precedes dementia by more than a year. |
2012-06-07 |
2023-08-12 |
Not clear |
| Koji Kasanuki, Eizo Iseki, Hiroshige Fujishiro, Ryoko Yamamoto, Shinji Higashi, Michiko Minegishi, Takashi Togo, Omi Katsuse, Hirotake Uchikado, Yoshiko Furukawa, Hiroaki Hino, Kenji Kosaka, Kiyoshi Sato, Heii Ara. Neuropathological investigation of the hypometabolic regions on positron emission tomography with [18F] fluorodeoxyglucose in patients with dementia with Lewy bodies. Journal of the neurological sciences. vol 314. issue 1-2. 2012-06-04. PMID:22041339. |
we performed a quantitative neuropathological examination of the hypometabolic regions on fdg pet in dementia with lewy bodies (dlb), alzheimer's disease (ad) and control cases. |
2012-06-04 |
2023-08-12 |
Not clear |
| Zuzana Walker, Jeffrey L Cumming. [123I]N-ω-fluoropropyl-2β-carbomethoxy-3β-(4-iodophenyl)nortropane single-photon emission computed tomography brain imaging in the diagnosis of dementia with Lewy bodies. Alzheimer's & dementia : the journal of the Alzheimer's Association. vol 8. issue 1. 2012-05-31. PMID:22024052. |
early, accurate diagnosis of dementia with lewy bodies (dlb), in particular its differentiation from alzheimer's disease, is important for optimal management, providing patients/carers with information about the likely symptomatology and illness course, allowing initiation of effective pharmacotherapy, and avoiding the consequences of neuroleptic sensitivity. |
2012-05-31 |
2023-08-12 |
Not clear |
| Zuzana Walker, Jeffrey L Cumming. [123I]N-ω-fluoropropyl-2β-carbomethoxy-3β-(4-iodophenyl)nortropane single-photon emission computed tomography brain imaging in the diagnosis of dementia with Lewy bodies. Alzheimer's & dementia : the journal of the Alzheimer's Association. vol 8. issue 1. 2012-05-31. PMID:22024052. |
[(123)i]fp-cit spect, by identifying the striatal dopaminergic deficit, can be a valuable diagnostic aid and can provide support to a clinical diagnosis of dlb in patients with dementia. |
2012-05-31 |
2023-08-12 |
Not clear |
| Masashi Takanashi, Nobutaka Hattor. [Neurodegenerative diseases]. Nihon rinsho. Japanese journal of clinical medicine. vol 70. issue 1. 2012-05-31. PMID:22413500. |
antipsychotic drugs may induce worsening of parkinsonism and neuroleptic malignant syndrome in pd and dementia lewy bodies(dlb). |
2012-05-31 |
2023-08-12 |
Not clear |