Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
Malin Wennström, Elisabet Londos, Lennart Minthon, Henrietta M Nielse. Altered CSF orexin and α-synuclein levels in dementia patients. Journal of Alzheimer's disease : JAD. vol 29. issue 1. 2012-09-21. PMID:22207004. |
neurodegenerative dementia, most frequently represented by alzheimer's disease (ad) and dementia with lewy bodies (dlb), is often accompanied by altered sleeping patterns and excessive daytime sleepiness. |
2012-09-21 |
2023-08-12 |
Not clear |
Yuko Saito, Shigeo Murayam. [Neuropathology]. Rinsho shinkeigaku = Clinical neurology. vol 51. issue 11. 2012-09-18. PMID:22277522. |
pathology of idiopathic parkinson disease (pd) can be summarized as a spectrum of lewy body (lb) disease (lbd) comprising pd, dementia with lb (dlb) and pure autonomic failure (paf). |
2012-09-18 |
2023-08-12 |
Not clear |
Joseph G Quinn, David T R Coulson, Simon Brockbank, Nancy Beyer, Rivka Ravid, Jan Hellemans, G Brent Irvine, Janet A Johnsto. α-Synuclein mRNA and soluble α-synuclein protein levels in post-mortem brain from patients with Parkinson's disease, dementia with Lewy bodies, and Alzheimer's disease. Brain research. vol 1459. 2012-09-18. PMID:22560502. |
α-synuclein is a neuronal protein implicated in the etiology of parkinson's disease (pd) and dementia with lewy bodies (dlb). |
2012-09-18 |
2023-08-12 |
human |
Monica Neri, Stefano Bonassi, Patrizia Russ. Genetic variations in CHRNA7 or CHRFAM7 and susceptibility to dementia. Current drug targets. vol 13. issue 5. 2012-09-17. PMID:22300029. |
the presence of memory impairment and cognitive deficits in the alzheimer's disease (ad), dementia with lewy bodies (dlb), and pick's disease (pid) has been associated to dysfunction of cholinergic transmission, possibly due to the loss of cholinergic neurons and to the elimination of nachr in dementia patients. |
2012-09-17 |
2023-08-12 |
Not clear |
K Kume, M Kikukawa, H Hanyu, Y Takata, T Umahara, H Sakurai, H Kanetaka, K Ohyashiki, J H Ohyashiki, T Iwamot. Telomere length shortening in patients with dementia with Lewy bodies. European journal of neurology. vol 19. issue 6. 2012-09-14. PMID:22288427. |
however, changes in telomere length in dementia with lewy bodies (dlb) remain unclear. |
2012-09-14 |
2023-08-12 |
Not clear |
Vikas Kotagal, Martijn L T M Müller, Daniel I Kaufer, Robert A Koeppe, Nicolaas I Bohne. Thalamic cholinergic innervation is spared in Alzheimer disease compared to parkinsonian disorders. Neuroscience letters. vol 514. issue 2. 2012-09-14. PMID:22414859. |
we investigated thalamic cholinergic afferent integrity by measuring ppn-thalamic (ppn-thal) acetylcholinesterase (ache) activity via pet imaging in alzheimer (ad), parkinson disease without dementia (pd), parkinson disease with dementia (pdd) and dementia with lewy bodies (dlb). |
2012-09-14 |
2023-08-12 |
human |
Hans Brunnström, Eva Lindberg, Elisabet Englun. Staging of Lewy-related pathology in dementia. Clinical neuropathology. vol 31. issue 4. 2012-09-14. PMID:22541783. |
lewy-related pathology is the characteristic feature of parkinson's disease with and without dementia and dementia with lewy bodies (dlb). |
2012-09-14 |
2023-08-12 |
Not clear |
Jin-Hyuck Kim, Jaeseol Park, Kyung-Ho Yu, Hyeo-Il Ma, Byung-Chul Lee, Imyel Kim, Yun Joong Ki. Prodromal dementia with lewy bodies manifesting as sertraline-induced parkinsonism: a case report. Alzheimer disease and associated disorders. vol 26. issue 2. 2012-09-13. PMID:21946016. |
to describe a patient with prodromal dementia with lewy bodies (dlb) manifesting as sertraline-induced parkinsonism. |
2012-09-13 |
2023-08-12 |
Not clear |
Ian McKeit. Dementia with Lewy bodies. Dialogues in clinical neuroscience. vol 6. issue 3. 2012-09-10. PMID:22033743. |
dementia with lewy bodies (dlb) is the second most common cause of neurodegenerative dementia in older people, accounting for 10% to 15% of all cases, it occupies part of a spectrum that includes parkinson's disease and primary autonomic failure. |
2012-09-10 |
2023-08-12 |
Not clear |
Ian McKeit. Dementia with Lewy bodies. Dialogues in clinical neuroscience. vol 6. issue 3. 2012-09-10. PMID:22033743. |
it is important to identify dlb patients accurately because they have specific symptoms, impairments, and functional disabilities thai differ from other common dementia syndromes such as alzheimer's disease, vascular cognitive impairment, and frontotemporal dementia. |
2012-09-10 |
2023-08-12 |
Not clear |
Margarete Delazer, Birgit Högl, Laura Zamarian, Johanna Wenter, Laura Ehrmann, Viola Gschliesser, Elisabeth Brandauer, Werner Poewe, Birgit Frausche. Decision making and executive functions in REM sleep behavior disorder. Sleep. vol 35. issue 5. 2012-09-05. PMID:22547893. |
irbd is often seen as an early sign of later evolving neurodegenerative disease, most importantly parkinson disease (pd) and lewy body dementia (dlb). |
2012-09-05 |
2023-08-12 |
Not clear |
Victor L Villemagne, Nobuyuki Okamura, Svetlana Pejoska, John Drago, Rachel S Mulligan, Gaël Chételat, Graeme O'Keefe, Gareth Jones, Hank F Kung, Michael Pontecorvo, Colin L Masters, Daniel M Skovronsky, Christopher C Row. Differential diagnosis in Alzheimer's disease and dementia with Lewy bodies via VMAT2 and amyloid imaging. Neuro-degenerative diseases. vol 10. issue 1-4. 2012-08-29. PMID:22261520. |
the noninvasive evaluation of nigrostriatal dopaminergic integrity by pet can provide useful information for the differential diagnosis between dementia with lewy bodies (dlb) and alzheimer's disease (ad). |
2012-08-29 |
2023-08-12 |
Not clear |
S Pablo Sardi, Priyanka Singh, Seng H Cheng, Lamya S Shihabuddin, Michael G Schlossmache. Mutant GBA1 expression and synucleinopathy risk: first insights from cellular and mouse models. Neuro-degenerative diseases. vol 10. issue 1-4. 2012-08-29. PMID:22327140. |
heterozygous mutations in the glucocerebrosidase gene (gba1) are associated with increased risk for α-synuclein aggregation disorders ('synucleinopathies'), which include parkinson's disease (pd) and dementia with lewy bodies (dlb). |
2012-08-29 |
2023-08-12 |
mouse |
Kajsa Stubendorff, Oskar Hansson, Lennart Minthon, Elisabet Londo. Differences in survival between patients with dementia with Lewy bodies and patients with Alzheimer's disease--measured from a fixed cognitive level. Dementia and geriatric cognitive disorders. vol 32. issue 6. 2012-08-28. PMID:22327504. |
the aim of this study was to compare survival in patients with alzheimer's disease (ad) and patients with dementia with lewy bodies (dlb). |
2012-08-28 |
2023-08-12 |
Not clear |
Simone A van den Berge, Josta T Kevenaar, Jacqueline A Sluijs, Elly M Ho. Dementia in Parkinson's Disease Correlates with α-Synuclein Pathology but Not with Cortical Astrogliosis. Parkinson's disease. vol 2012. 2012-08-23. PMID:22577599. |
we have examined these proteins by immunohistochemistry in the frontal cortex and by western blot in csf of cases with pd, pd with dementia (pdd), dementia with lewy bodies (dlb) and nondemented controls. |
2012-08-23 |
2023-08-12 |
Not clear |
Simone A van den Berge, Josta T Kevenaar, Jacqueline A Sluijs, Elly M Ho. Dementia in Parkinson's Disease Correlates with α-Synuclein Pathology but Not with Cortical Astrogliosis. Parkinson's disease. vol 2012. 2012-08-23. PMID:22577599. |
we were neither able to detect an increase in cortical astrogliosis in pd, pdd, or dlb nor could we observe a correlation between the extent of astrogliosis and the degree of dementia. |
2012-08-23 |
2023-08-12 |
Not clear |
Christine Lund Kragh, Kiren Ubhi, Tony Wyss-Coray, Tony Wyss-Corey, Eliezer Maslia. Autophagy in dementias. Brain pathology (Zurich, Switzerland). vol 22. issue 1. 2012-08-20. PMID:22150925. |
alzheimer's disease (ad) is the most common cause of a progressive dementia, followed by dementia with lewy bodies (dlb), frontotemporal dementia (ftd), (vad) and hiv-associated neurocognitive disorders (hand). |
2012-08-20 |
2023-08-12 |
Not clear |
Marjolein B Aerts, Rianne A J Esselink, Jugen A H R Claassen, Wilson Farid Abdo, Bastiaan R Bloem, Marcel M Verbee. CSF tau, Aβ42, and MHPG differentiate dementia with Lewy bodies from Alzheimer's disease. Journal of Alzheimer's disease : JAD. vol 27. issue 2. 2012-08-16. PMID:21841257. |
differentiating dementia with lewy bodies (dlb) from alzheimer's disease (ad) can be difficult because of the substantial overlap in clinical features. |
2012-08-16 |
2023-08-12 |
Not clear |
David K Johnson, Amber S Watts, Benjamin A Chapin, RaeAnn Anderson, Jeffrey M Burn. Neuropsychiatric profiles in dementia. Alzheimer disease and associated disorders. vol 25. issue 4. 2012-08-13. PMID:22086220. |
we compared patterns of neuropsychiatric symptoms across 4 dementia types [alzheimer disease (ad), vascular dementia (vad), dementia with lewy bodies (dlb), and parkinson disease dementia], and 2 mixed groups (ad/vad and ad/dlb) in sample of 2,963 individuals from the national alzheimer's coordinating center uniform data set between september 2005 and june 2008. |
2012-08-13 |
2023-08-12 |
Not clear |
David K Johnson, Amber S Watts, Benjamin A Chapin, RaeAnn Anderson, Jeffrey M Burn. Neuropsychiatric profiles in dementia. Alzheimer disease and associated disorders. vol 25. issue 4. 2012-08-13. PMID:22086220. |
dlb and the mixed dementias had more complex symptom profiles. |
2012-08-13 |
2023-08-12 |
Not clear |