| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Ian McKeit. Dementia with Lewy bodies. Dialogues in clinical neuroscience. vol 6. issue 3. 2012-09-10. PMID:22033743. |
it is important to identify dlb patients accurately because they have specific symptoms, impairments, and functional disabilities thai differ from other common dementia syndromes such as alzheimer's disease, vascular cognitive impairment, and frontotemporal dementia. |
2012-09-10 |
2023-08-12 |
Not clear |
| Margarete Delazer, Birgit Högl, Laura Zamarian, Johanna Wenter, Laura Ehrmann, Viola Gschliesser, Elisabeth Brandauer, Werner Poewe, Birgit Frausche. Decision making and executive functions in REM sleep behavior disorder. Sleep. vol 35. issue 5. 2012-09-05. PMID:22547893. |
irbd is often seen as an early sign of later evolving neurodegenerative disease, most importantly parkinson disease (pd) and lewy body dementia (dlb). |
2012-09-05 |
2023-08-12 |
Not clear |
| Victor L Villemagne, Nobuyuki Okamura, Svetlana Pejoska, John Drago, Rachel S Mulligan, Gaël Chételat, Graeme O'Keefe, Gareth Jones, Hank F Kung, Michael Pontecorvo, Colin L Masters, Daniel M Skovronsky, Christopher C Row. Differential diagnosis in Alzheimer's disease and dementia with Lewy bodies via VMAT2 and amyloid imaging. Neuro-degenerative diseases. vol 10. issue 1-4. 2012-08-29. PMID:22261520. |
the noninvasive evaluation of nigrostriatal dopaminergic integrity by pet can provide useful information for the differential diagnosis between dementia with lewy bodies (dlb) and alzheimer's disease (ad). |
2012-08-29 |
2023-08-12 |
Not clear |
| S Pablo Sardi, Priyanka Singh, Seng H Cheng, Lamya S Shihabuddin, Michael G Schlossmache. Mutant GBA1 expression and synucleinopathy risk: first insights from cellular and mouse models. Neuro-degenerative diseases. vol 10. issue 1-4. 2012-08-29. PMID:22327140. |
heterozygous mutations in the glucocerebrosidase gene (gba1) are associated with increased risk for α-synuclein aggregation disorders ('synucleinopathies'), which include parkinson's disease (pd) and dementia with lewy bodies (dlb). |
2012-08-29 |
2023-08-12 |
mouse |
| Kajsa Stubendorff, Oskar Hansson, Lennart Minthon, Elisabet Londo. Differences in survival between patients with dementia with Lewy bodies and patients with Alzheimer's disease--measured from a fixed cognitive level. Dementia and geriatric cognitive disorders. vol 32. issue 6. 2012-08-28. PMID:22327504. |
the aim of this study was to compare survival in patients with alzheimer's disease (ad) and patients with dementia with lewy bodies (dlb). |
2012-08-28 |
2023-08-12 |
Not clear |
| Simone A van den Berge, Josta T Kevenaar, Jacqueline A Sluijs, Elly M Ho. Dementia in Parkinson's Disease Correlates with α-Synuclein Pathology but Not with Cortical Astrogliosis. Parkinson's disease. vol 2012. 2012-08-23. PMID:22577599. |
we have examined these proteins by immunohistochemistry in the frontal cortex and by western blot in csf of cases with pd, pd with dementia (pdd), dementia with lewy bodies (dlb) and nondemented controls. |
2012-08-23 |
2023-08-12 |
Not clear |
| Simone A van den Berge, Josta T Kevenaar, Jacqueline A Sluijs, Elly M Ho. Dementia in Parkinson's Disease Correlates with α-Synuclein Pathology but Not with Cortical Astrogliosis. Parkinson's disease. vol 2012. 2012-08-23. PMID:22577599. |
we were neither able to detect an increase in cortical astrogliosis in pd, pdd, or dlb nor could we observe a correlation between the extent of astrogliosis and the degree of dementia. |
2012-08-23 |
2023-08-12 |
Not clear |
| Christine Lund Kragh, Kiren Ubhi, Tony Wyss-Coray, Tony Wyss-Corey, Eliezer Maslia. Autophagy in dementias. Brain pathology (Zurich, Switzerland). vol 22. issue 1. 2012-08-20. PMID:22150925. |
alzheimer's disease (ad) is the most common cause of a progressive dementia, followed by dementia with lewy bodies (dlb), frontotemporal dementia (ftd), (vad) and hiv-associated neurocognitive disorders (hand). |
2012-08-20 |
2023-08-12 |
Not clear |
| Marjolein B Aerts, Rianne A J Esselink, Jugen A H R Claassen, Wilson Farid Abdo, Bastiaan R Bloem, Marcel M Verbee. CSF tau, Aβ42, and MHPG differentiate dementia with Lewy bodies from Alzheimer's disease. Journal of Alzheimer's disease : JAD. vol 27. issue 2. 2012-08-16. PMID:21841257. |
differentiating dementia with lewy bodies (dlb) from alzheimer's disease (ad) can be difficult because of the substantial overlap in clinical features. |
2012-08-16 |
2023-08-12 |
Not clear |
| David K Johnson, Amber S Watts, Benjamin A Chapin, RaeAnn Anderson, Jeffrey M Burn. Neuropsychiatric profiles in dementia. Alzheimer disease and associated disorders. vol 25. issue 4. 2012-08-13. PMID:22086220. |
we compared patterns of neuropsychiatric symptoms across 4 dementia types [alzheimer disease (ad), vascular dementia (vad), dementia with lewy bodies (dlb), and parkinson disease dementia], and 2 mixed groups (ad/vad and ad/dlb) in sample of 2,963 individuals from the national alzheimer's coordinating center uniform data set between september 2005 and june 2008. |
2012-08-13 |
2023-08-12 |
Not clear |
| David K Johnson, Amber S Watts, Benjamin A Chapin, RaeAnn Anderson, Jeffrey M Burn. Neuropsychiatric profiles in dementia. Alzheimer disease and associated disorders. vol 25. issue 4. 2012-08-13. PMID:22086220. |
dlb and the mixed dementias had more complex symptom profiles. |
2012-08-13 |
2023-08-12 |
Not clear |
| Giorgio Treglia, Ernesto Caso. Diagnostic performance of myocardial innervation imaging using MIBG scintigraphy in differential diagnosis between dementia with lewy bodies and other dementias: a systematic review and a meta-analysis. Journal of neuroimaging : official journal of the American Society of Neuroimaging. vol 22. issue 2. 2012-08-10. PMID:21091814. |
this study was designed to review the diagnostic performance of myocardial innervation imaging using iodine-123-metaiodobenzylguanidine (mibg) scintigraphy in differential diagnosis between dementia with lewy bodies (dlb) and other dementias. |
2012-08-10 |
2023-08-12 |
Not clear |
| P G Foulds, O Yokota, A Thurston, Y Davidson, Z Ahmed, J Holton, J C Thompson, H Akiyama, T Arai, M Hasegawa, A Gerhard, D Allsop, D M A Man. Post mortem cerebrospinal fluid α-synuclein levels are raised in multiple system atrophy and distinguish this from the other α-synucleinopathies, Parkinson's disease and Dementia with Lewy bodies. Neurobiology of disease. vol 45. issue 1. 2012-07-23. PMID:21856424. |
because pd (and the related disorder dementia with lewy bodies (dlb)) and msa are characterised by the deposition of aggregated forms of α-synuclein protein (α-syn) in the brain, whereas cbs and psp are tauopathies, we have developed immunoassays to detect levels of total and oligomeric forms of α-syn, and phosphorylated and phosphorylated oligomeric forms of α-syn, within body fluids, in an attempt to find a biomarker that will differentiate between these disorders. |
2012-07-23 |
2023-08-12 |
human |
| Hiroyasu Akatsu, Akira Hori, Takayuki Yamamoto, Mari Yoshida, Maya Mimuro, Yoshio Hashizume, Ikuo Tooyama, Eric M Yezdime. Transition metal abnormalities in progressive dementias. Biometals : an international journal on the role of metal ions in biology, biochemistry, and medicine. vol 25. issue 2. 2012-07-23. PMID:22080191. |
abnormal distributions of transition metals inside the brain are potential diagnostic markers for several central nervous system diseases, including alzheimer's disease (ad), parkinson's disease, dementia with lewy bodies (dlb), bipolar disorders and depression. |
2012-07-23 |
2023-08-12 |
Not clear |
| Katsuyoshi Mizukam. [Dementia with Lewy bodies and depressive state]. Seishin shinkeigaku zasshi = Psychiatria et neurologia Japonica. vol 114. issue 3. 2012-07-19. PMID:22568063. |
depressive states are often observed in patients with dementia with lewy bodies (dlb) during the clinical course and the prodromal stage. |
2012-07-19 |
2023-08-12 |
Not clear |
| Kensaku Kasuga, Takeshi Ikeuch. [Cerebrospinal fluid and plasma biomarkers for dementia with lewy bodies]. Brain and nerve = Shinkei kenkyu no shinpo. vol 64. issue 5. 2012-07-17. PMID:22570064. |
dementia with lewy bodies (dlb) is the second most common cause of neurodegenerative dementia in the elderly. |
2012-07-17 |
2023-08-12 |
Not clear |
| Kensaku Kasuga, Takeshi Ikeuch. [Cerebrospinal fluid and plasma biomarkers for dementia with lewy bodies]. Brain and nerve = Shinkei kenkyu no shinpo. vol 64. issue 5. 2012-07-17. PMID:22570064. |
we have previously reported that the α-synuclein levels in cerebrospinal fluid (csf) are significantly lower in patients with dlb than in patients with other types of dementia. |
2012-07-17 |
2023-08-12 |
Not clear |
| Kelvin C Luk, Victoria M Kehm, Bin Zhang, Patrick O'Brien, John Q Trojanowski, Virginia M Y Le. Intracerebral inoculation of pathological α-synuclein initiates a rapidly progressive neurodegenerative α-synucleinopathy in mice. The Journal of experimental medicine. vol 209. issue 5. 2012-07-16. PMID:22508839. |
however, the factors that trigger aggregation of α-synuclein (α-syn), the principal component of the intraneuronal inclusions known as lewy bodies (lbs), and lewy neurites (lns), which characterize parkinson's disease (pd) and dementia with lbs (dlb), are poorly understood. |
2012-07-16 |
2023-08-12 |
mouse |
| L Warr, Z Walke. Identification of biomarkers in Lewy-body disorders. The quarterly journal of nuclear medicine and molecular imaging : official publication of the Italian Association of Nuclear Medicine (AIMN) [and] the International Association of Radiopharmacology (IAR), [and] Section of the Society of.... vol 56. issue 1. 2012-07-05. PMID:22460159. |
dementia with lewy bodies (dlb) may account for up to 30% of all dementia cases. |
2012-07-05 |
2023-08-12 |
Not clear |
| L Warr, Z Walke. Identification of biomarkers in Lewy-body disorders. The quarterly journal of nuclear medicine and molecular imaging : official publication of the Italian Association of Nuclear Medicine (AIMN) [and] the International Association of Radiopharmacology (IAR), [and] Section of the Society of.... vol 56. issue 1. 2012-07-05. PMID:22460159. |
the symptoms of dlb can be difficult to disentangle from other dementia subtypes, particularly alzheimer's disease (ad). |
2012-07-05 |
2023-08-12 |
Not clear |